scholarly journals The premorbid background and the most significant predictors of the development chronic gastroduodenal pathology in children

2021 ◽  
pp. 78-85
Author(s):  
Sh. T. Turdieva
Keyword(s):  
Helicobacter Pylori ◽  
Relative Risk ◽  
Confidence Interval ◽  
Fast Food ◽  
Overweight And Obesity ◽  
School Age ◽  
Spicy Food ◽  
Intestinal Infections ◽  
History Of ◽  
Confidence Interval Limit

The study features of premorbid background and the most significant predictors of the development of chronic gastroduodenal pathology in children and adolescents of school age. Materials and methods. The results of screening questioning of schoolchildren with chronic gastroduodenal pathology (CGDP) - n=286, and practically healthy schoolchildren - n=1023, from 6 to 15 years agо. The survey conducted according to the questionnaire developed by us, which includes 24 questions. The relative risk (RR) calculated using traditional statistical formulas with a confidence interval limit 95% CI (confidence interval). Results. In this study, it was found that the main nutritional reason for the development of СGDP in schoolchildren is a malnutrition - 69.2%, RR=2.25 (CI=1.81-2.79), and food for fast food - 65.0%, RR=4.19 (CI=3.45-5.09). The least observed was the abuse of spicy food - 4.9%, RR=1.24 (CI=0.80-1.91). The 42.7% of patients were constantly in a state of heightened psychoemotional stress - RR=1.6 (CI=1.32-1.93). Helicobacter pylori (HP) - infection was diagnosed in 57.7% of patients - RR=4.84 (CI=4.04-5.79), 29.0% of patients underwent acute intestinal infections - RR=2.74 (CI=2.29-3.27), and 62.3% had a history of hereditary burden of chronic diseases of the gastrointestinal tract - RR=1.65 (CI=1.34-2.02) Conclusion. The most significant predictors and premorbid backgrounds for the development of СGDP in schoolchildren are HP-infection (RR=4.84; CI=4.04-5.79; RRR=3.84), food for fast food (RR=4.19; CI=3.45-5,09; RRR=3.20) with the development of overweight and obesity (RR=3.64; CI=2.97-4.47; RRR=2.64), the presence of chronic foci of infection (RR=2.58; CI=2.05-3.23; RRR=1.58).

Diet, Lifestyle and Venous Thromboembolism (VTE) in Thai Population.

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 1414-1414
Author(s):  
Ponlapat Rojnuckarin ◽  
Lantarima Bhoopat ◽  
Narin Hiransuthikul ◽  
Tanin Intragumtornchai
Keyword(s):  
Venous Thromboembolism ◽  
National Health ◽  
Fast Food ◽  
Conflicts Of Interest ◽  
Health Examination ◽  
Thai Population ◽  
P Values ◽  
Spicy Food ◽  
Prevalence Of Obesity ◽  
History Of

Abstract Abstract 1414 Poster Board I-437 Introduction: Previous studies demonstrated that the incidence of venous thromboembolism (VTE) was very low among Thais (Lancet. 1975; 1: 1357-8, Arch Intern Med. 1988; 148: 1349-53). However, recent investigations in Asian countries strongly indicated that VTE is currently much more common, approaching rates in the western countries. Meanwhile, the latest National Health Surveys showed the inadequate vegetable and fruit intakes, as well as an obvious rise in prevalence of obesity in Thai population. Therefore, changing diet and behaviors are suspected to contribute to this marked increase in the VTE incidence. Patients and Methods The case-control study was conducted. Cases were objectively confirmed venous thromboembolism. Patients with underlying cancer, antiphospholipid syndrome and arterial thrombosis were excluded. Controls are age- and sex-matched healthy volunteers. Body mass indices, history of alcohol intake, smoking and exercise were obtained. Food consumptions were interviewed using a food frequency questionnaire modified from the Thailand National Health Examination Survey III previously validated in Thai population. Results: There were 97 cases and 195 controls. The mean age was 54.6 yr, ranging from 17-93 yr, and 70% were female. VTE was significantly associated with low vegetable intakes (below 3.5 standard servings per day) compared with controls (Odd ratio [OR] 2.5, 95% confidence interval [CI] 1.37-4.67), while there was no difference in fruit consumption (p values =0.53). Notably, low fish intakes (below 0.1 serving per day, OR 3.9, 95%CI 1.58-9.71) and having spicy food less than once a week (OR 1.9, 95%CI 1.15-3.18) also increased the risk. The meat, fat, carbohydrate, fast food or alcohol consumptions were similar. In addition, VTE was associated with overweight (OR 2.1, 95%CI 1.21-3.62) and obesity (OR 3.1, 95%CI 1.46-6.74, p values = 0.002 and 0.001, respectively). Furthermore, estrogen uses also increased the risk of VTE (OR 3.7, 95% CI 1.05-13.20, p=0.02), while smoking and lack of exercise did not. Conclusions: Low vegetable, fish and spicy food intakes, as well as obesity and hormonal uses, are the risk factors for VTE in Thai population. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Hubungan Obesitas dengan Usia, Jenis Kelamin, Genetik, Asupan Makanan dan Kebiasaan di Dusun Bangkan

2021 ◽  
pp. 55-67
Author(s):  
Eka Risdayani ◽  
Armanto Makmun
Keyword(s):  
Physical Activity ◽  
Family History ◽  
Fast Food ◽  
Overweight And Obesity ◽  
Bivariate Analysis ◽  
Sleep Habits ◽  
Sugary Drinks ◽  
History Of ◽  
History Of Obesity ◽  
The Relationship

Background: Obesity is a condition of excess fat accumulation in the body's adipose tissue which can be influenced by physical activity, food intake, genetic factors, sleep habits, age and gender. The incidence rate in Indonesia tends to increase as seen from the Riskesdas 2007, 2013 and 2018 data, namely 10.5%, 14.8%, and 21.8%. Objective: To determine the relationship between obesity and age, gender, level of physical activity, eating habits, genetics and sleep duration. Methods: This research is a quantitative study with a cross sectional approach. Data collection was carried out through a questionnaire. The research sample is a sample with overweight and obesity obtained a sample of 80 samples. The data analysis was conducted, namely univariate and bivariate analysis using the chi-square test. Results: 36.3% of respondents are overweight and 63.8% obese. Most of the respondents were> 18 years old. The results showed that obesity was significantly associated with age (p = 0.016), gender (p = 0.010), physical activity (p = 0.025), frequency of eating (p = 0.015), frequency of heavy eating (p = 0.040), drinking- sugary drinks (0.025), fast food (p = 0.025) daily portions of food (p = 0.025) and a family history of obesity (p = 0.007). Conversely, consumption of snacks (p = 0.731), consumption of fibrous foods (p = 0.089), the relationship between breakfast (p = 0.776), the relationship between sleep time (p = 0.243). Conclusion: Age, gender, physical activity, frequency of eating, frequency of heavy eating, drinking sugary drinks, consumption of fast food, daily food portions and a family history of obesity have a significant relationship which can be a contributing factor to obesity

Preservation of the Greater Occipital Nerve During Suboccipital Craniectomy Results in a Paradoxical Increase in Postoperative Headaches

Neurosurgery ◽  
2015 ◽  
Vol 76 (4) ◽  
pp. 435-440 ◽  
Author(s):  
Tomas Garzon-Muvdi ◽  
Christopher Jackson ◽  
Alfred P. See ◽  
Graeme F. Woodworth ◽  
Rafael J. Tamargo
Keyword(s):  
Relative Risk ◽  
Confidence Interval ◽  
Wound Infection ◽  
Univariate Analysis ◽  
Multivariate Logistic Regression Analysis ◽  
Occipital Nerve ◽  
Suboccipital Craniectomy ◽  
Greater Occipital Nerve ◽  
History Of ◽  
Nature Preservation

Abstract BACKGROUND: Injury to the greater occipital nerve (GON) during suboccipital/retrosigmoid craniectomy (SOC) has been postulated as an etiology of postoperative headaches (HAs). We hypothesized that severe postoperative HAs may be due to the division of the GON during dissection. OBJECTIVE: To determine whether the GON plays an important role in the development of postoperative HAs. METHODS: A retrospective review of prospectively accrued patients undergoing SOC by 1 neurosurgeon at Johns Hopkins from 1995 to 2009 was performed. A total of 280 patients were included in the study. HA was categorized into 3 groups according to the severity and impact on daily activities. Data were analyzed using a stepwise multivariate logistic regression analysis to identify independent factors associated with HA development. Patients with a history of preoperative HAs and migraine were excluded from the analysis. RESULTS: In this cohort, new postoperative severe HAs at last follow-up visit were found in 19% of patients. By multivariate analysis, only GON preservation (relative risk: 1.49; 95% confidence interval: 1.00-2.34; P = 0.05) and wound infection (relative risk: 2.29; 95% confidence interval: 0.91-4.25; P = 0.07) were statistically significant. By univariate analysis, positive dependent associations included GON preservation (P < .01), reconstruction of the porus with hydroxyapatite cement (P = 0.02), and wound infection (P < 0.01). Statistically significant differences in the incidence of HA after surgery were found in patients in whom the GON was preserved compared with patients in whom the GON was divided (P = 0.035). CONCLUSION: Postoperative debilitating HAs are a common complication after SOC. Although these HAs are probably multifactorial in nature, preservation of the GON during SOC is independently associated with postoperative debilitating HAs.

scholarly journals Pattern and Determinants of Overweight and Obesity Among Future Physicians

2014 ◽  
Vol 4 (1) ◽  
pp. 323-329
Author(s):  
M Basu ◽  
P Das ◽  
G Dhar ◽  
S Datta ◽  
S Chattopaddhyay ◽  
...  
Keyword(s):  
Family History ◽  
Fast Food ◽  
Fruits And Vegetables ◽  
Dietary Habits ◽  
General Pattern ◽  
Simple Random Sampling ◽  
Overweight And Obesity ◽  
Medical Group ◽  
Medical Undergraduate ◽  
History Of

Background   Overweight including obesity is a leading cause of present day morbidity and kills more people than underweight. Keeping this background in mind this study had been conducted to establish the pattern of overweight and obesity in the midst of undergraduate medical group and to find out the association of overweight (plump) and obesity with probable hazardous factors. Materials and Methods This descriptive observational study had been conducted among undergraduate medical group for the duration of May to June 2011. Simple random sampling was adopted to select the students under study. A pretested, predesigned self-administered questionnaire was utilized for data collection. Body Mass Index (BMI) was assessed through weight and height and acted as forecaster of heavy figure and or obesity. Overweight and or obesity were analyzed to see the association with certain socio-demographic variables, dietary habits, family history of overweight and or obesity, life style issues, computer use etc. After collection of data, these were analyzed using tabulation, proportion and Chi square through Epi-Info software. Results The study subjects were young adults. The general pattern of overweight (plump) and obesity was 18.0 percent and 4.0 percent respectively. Overweight and or obesity was found significantly high among male students, fast food and soft drinks takers, low takers of fruits and vegetables, alcohol consumers, students with lack of exercise and family history of obesity. Overweight and obesity were not found associated with type of diet (vegetarian or non-vegetarian) and smoking. Conclusion Presence of probable associated factors with regard to overweight (plump) and obesity exists amid medical undergraduate pupils.DOI: http://dx.doi.org/10.3126/nje.v4i1.10134 Nepal Journal of Epidemiology 2014;4 (1): 323-329

Natural history of helicobacter pylori infection from infancy to adulthood: A 21-year follow-up cohort study

2001 ◽  
Vol 120 (5) ◽  
pp. A128-A128 ◽  
Author(s):  
H MALATY ◽  
D GRAHAM ◽  
A ELKASABANY ◽  
S REDDY ◽  
S SRINIVASAN ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Cohort Study ◽  
Natural History ◽  
Helicobacter Pylori Infection ◽  
History Of

scholarly journals Efficacy of two-week therapy with doxycycline-based quadruple regimen versus levofloxacin concomitant regimen for helicobacter pylori infection: a prospective single-center randomized controlled trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Marouf Alhalabi ◽  
Mohammed Waleed Alassi ◽  
Kamal Alaa Eddin ◽  
Khaled Cheha
Keyword(s):  
Clinical Trial ◽  
Helicobacter Pylori ◽  
Confidence Interval ◽  
Odds Ratio ◽  
Controlled Trial ◽  
Helicobacter Pylori Infection ◽  
First Line ◽  
Link Type ◽  
Syrian Population

Abstract Background Antibiotic-resistance reduces the efficacy of conventional triple therapy for Helicobacter Pylori infections worldwide, which necessitates using various treatment protocols. We used two protocols, doxycycline-based quadruple regimen and concomitant levofloxacin regimen. The aim was to assess the effectiveness of doxycycline-based quadruple regimen for treating Helicobacter Pylori infections compared with levofloxacin concomitant regimen as empirical first-line therapy based on intention-to-treat (ITT) and per-protocol analyses (PPA) in Syrian population. Settings and design An open-label, randomised, parallel, superiority clinical trial. Methods We randomly assigned 78 naïve patients who tested positive for Helicobacter Pylori gastric infection, with a 1:1 ratio to (D-group) which received (bismuth subsalicylate 524 mg four times daily, doxycycline 100 mg, tinidazole 500 mg, and esomeprazole 20 mg, each twice per day for 2 weeks), or (L-group) which received (levofloxacin 500 mg daily, tinidazole 500 mg, amoxicillin 1000 mg, and esomeprazole 20 mg each twice per day for two weeks). We confirmed Helicobacter Pylori eradication by stool antigen test 8 weeks after completing the treatment. Results Thirty-nine patients were allocated in each group. In the D-group, 38 patients completed the follow-up, 30 patients were cured. While in the L-group, 39 completed the follow-up, 32patients were cured. According to ITT, the eradication rates were 76.92%, and 82.05%, for the D-group and L-group respectively. Odds ratio with 95% confidence interval was 1.371 [0.454–4.146]. According to PPA, the eradication rates were 78.9%, and 82.05% for the D-group and L-group respectively. The odds ratio with 95% confidence interval was 1.219 [0.394–3.774]. We didn’t report serious adverse effects. Conclusions Levofloxacin concomitant therapy wasn’t superior to doxycycline based quadruple therapy. Further researches are required to identify the optimal first-line treatment for Helicobacter-Pylori Infection in the Syrian population. Trial registration We registered this study as a standard randomized clinical trial (Clinicaltrial.gov, identifier-NCT04348786, date:29-January-2020).

scholarly journals Associations of community, famliy and early individual factors with body mass index z-scores trajectories among Chinese children and adolescents

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jing Liang ◽  
Si Zheng ◽  
Xuyang Li ◽  
Dianmin Xiao ◽  
Peigang Wang
Keyword(s):  
Overweight And Obesity ◽  
Growth Patterns ◽  
Chinese Children ◽  
School Age ◽  
Critical Window ◽  
Community Factors ◽  
Targeted Interventions ◽  
Individual Family ◽  
Class 1 ◽  
Z Scores

AbstractThe prevalence of childhood overweight and obesity is increasing. This study aimed to examine trajectories of BMI z-scores among Chinese children and the potential determinants including early individual, family and community factors. Group-based trajectory modeling was employed to identify BMI z-scores trajectories of children aged 2–18 years using the five waves data (2010, 2012, 2014, 2016, and 2018) of the China Family Panel Studies (CFPS). Multivariate logistic regression was conducted to determine the association between early individual, family, community factors and BMI z-scores trajectories of children. We identified three trajectories for boys and girls, named Class 1 as “not-overweight”, Class 2 as “persistent rapid descending but overweight during pre-school age”, and Class 3 as “rapid rising up to school age and then become-overweight” class. Macrosomia (OR 1.772; 95% CI 1.188–2.644) and being a single child (OR 2.038; 95% CI 1.453–2.859) were more likely to belong in Class 3 among boys. Girls living in the advantaged communities (OR 1.539; 95% CI 1.052–2.252), rural-living (OR 1.558; 95% CI 1.133–2.142) and with none social integration (OR 1.496; 95% CI 1.07–2.091) were more likely to belong in Class 2. There are heterogeneous BMI z-scores trajectories of children aged 2–18, and pre-school age is a critical window that could predict the long-term growth patterns. BMI z-scores trends need to be monitored during pre-school age, focusing on those at higher risk of later overweight obesity status, and targeted interventions at the early individual, family, community levels are essential.

scholarly journals Descriptive Epidemiology of Rescue-Related Fatal Drowning in Turkey

2021 ◽  
Vol 18 (12) ◽  
pp. 6613
Author(s):  
Ali Işın ◽  
Adnan Turgut ◽  
Amy E. Peden
Keyword(s):  
Public Health ◽  
Retrospective Study ◽  
Relative Risk ◽  
Confidence Interval ◽  
Descriptive Epidemiology ◽  
Death Registry ◽  
Public Health Threat ◽  
Reduction Strategies ◽  
Media Reports ◽  
Risk Reduction Strategies

Drowning is a public-health threat and a leading cause of injury-related death. In Turkey, drowning results in 900 fatalities annually, and the rate is rising. As data on rescue-related drowning are scarce, this retrospective study explores the epidemiology of fatal drowning among rescuers in Turkey. As there are no routinely collected death registry data on drowning in Turkey, data were sourced from media reports of incidents between 2015 and 2019. Rescuer fatalities were analysed by age, sex, activity prior to rescue, location, incident day of week and season, and place of death. Statistical analyses comprised X2 tests of significance (p < 0.05) and calculation of relative risk (95% confidence interval) using fatality rates. In total, 237 bystander rescuers drowned (90% male; 35% 15–24 years). In 33% of cases, the primary drowning victim (PDV) was successfully rescued, while in 46% of cases the rescue resulted in multiple drowning fatalities (mean = 2.29; range 1–5 rescuers). Rescues were more likely to be successful in saving the PDV if undertaken at the beach/sea (X2 = 29.147; p < 0.001), while swimming (X2 = 12.504; p = 0.001), or during summer (X2 = 8.223; p = 0.029). Risk of bystander rescue-related fatal drowning was twice as high on weekdays compared to on weekends (RR = 2.04; 95%CI: 1.56–2.67). While bystanders play an important role in reducing drowning, undertaking a rescue is not without risk and can lead to multiple drowning incidents. Training in rescue and resuscitation skills (especially the prioritization of non-contact rescues) coupled with increasing awareness of drowning risk, are risk-reduction strategies which should be explored in Turkey.

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