scholarly journals Low-Intensity Scheduled Morning Exercise for Adolescents with a Late Chronotype: A Novel Treatment to Improve Sleep Health

2021 ◽  
Author(s):  
Christin Lang ◽  
Cele Richardson ◽  
Michelle Short ◽  
Michael Gradisar
Keyword(s):  
Real Life ◽  
Exercise Group ◽  
Health Concern ◽  
Control Group ◽  
Contributing Factors ◽  
Laboratory Findings ◽  
Daytime Functioning ◽  
Circadian Timing ◽  
Low Intensity ◽  
Dim Light

Study Objectives. During adolescence, an interplay between biological and environmental factors leads to constrained sleep duration and timing. Given the importance of restorative sleep for cognitive, emotional, and physical health during this developmental period, the high prevalence of sleep deprivation is a public health concern. One of the primary contributing factors is the normative delay of the circadian rhythm. Therefore, the present study aimed to evaluate the effect of a gradually advanced morning exercise schedule (30 min shift each day) completed for 45 minutes on 5 consecutive mornings, on circadian timing and daytime functioning of adolescents with a late chronotype, compared to a sedentary control group. Methods. 19 sedentary male adolescents aged 15-18 years spent one week of school holiday at the sleep laboratory. Morning procedure included either 45 min walking on a treadmill or sedentary activities in dim light. Saliva dim light melatonin onset (DLMO), evening sleepiness and daytime functioning were assessed during the first and last night of laboratory attendance. Results. The morning exercise group had significantly advanced (earlier) circadian timing (27.5 min ± 32.0), while sedentary activity resulted in a phase delay (-34.3 min ± 53.2). Morning exercise also led to higher evening sleepiness in the earlier hours of the night, but not at bedtime. Mood measures reduced meaningfully in both study conditions.Conclusions. These findings highlight the preventative effect of low-intensity morning exercise among this population. Future studies are needed to test the transference of these laboratory findings to adolescents’ real life.

Synergistic Effects of Low-Intensity Exercise Conditioning and β-Blockade on Cardiovascular and Autonomic Adaptation in Pre- and Postmenopausal Women With Hypertension

2012 ◽  
Vol 15 (4) ◽  
pp. 433-442 ◽  
Author(s):  
Catherine L. Goldie ◽  
C. Ann Brown ◽  
Sylvia M. J. Hains ◽  
Joel L. Parlow ◽  
Richard Birtwhistle
Keyword(s):  
Baroreflex Sensitivity ◽  
Synergistic Effects ◽  
Exercise Group ◽  
Rate Pressure Product ◽  
Control Group ◽  
Cardiac Autonomic Function ◽  
Low Intensity ◽  
Walking Program ◽  
Low Intensity Exercise ◽  
Sedentary Women

The effects of a 12-week low-intensity exercise conditioning program (walking) on blood pressure (BP), heart rate (HR), rate–pressure product (RPP), and cardiac autonomic function were measured in 40 sedentary women with hypertension. Women were assigned to either an exercise group ( n = 20) or a control group ( n = 20), matched for β-blockade treatment. They underwent testing at the beginning and at the end of the 12-week study period in three conditions: supine rest, standing, and low-intensity steady state exercise. The exercise group participated in a 12-week, low-intensity walking program, while the control group continued with usual sedentary activity. Compared with the control group, women in the exercise group showed reductions in systolic and diastolic BP and RPP (i.e., the estimated cardiac workload). β-Blockers increased baroreflex sensitivity and lowered BP and HR in all participants; however, those in the exercise group showed the effects of both treatments: a greater reduction in HR and RPP. The combination of exercise training and β-blockade produces cardiac and autonomic adaptations that are not observed with either treatment alone, suggesting that β-blockade enhances the conditioning effects of low-intensity exercise in women with hypertension.

scholarly journals The Effect of Low and Moderate Exercise on Hyperuricemia: Protocol for a Randomized Controlled Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Yuning Hou ◽  
Renyan Ma ◽  
Song Gao ◽  
Keneilwe Kenny Kaudimba ◽  
Hongmei Yan ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Heart Rate ◽  
Exercise Group ◽  
Moderate Intensity ◽  
Controlled Study ◽  
Control Group ◽  
Maximum Heart Rate ◽  
Moderate Intensity Exercise ◽  
Low Intensity ◽  
Low Intensity Exercise

BackgroundHyperuricemia (HUA) is a metabolic disease by purine metabolism disorders. It is a risk factor for many chronic diseases, including diabetes, hypertension, and heart disease. Studies have shown that exercise can effectively reduce serum uric acid (SUA), but the optimal exercise dose, intensity, and mode of exercise for improving HUA have not been verified in clinical studies. Therefore, this study aims to explore the effect of different exercise intensities in improving SUA of patients with HUA.Methods and AnalysisA randomized, single-blind, parallel controlled trial will be conducted in this study. 186 HUA patients who meet the inclusion criteria will be randomly divided into a 1:1:1 ratio (1): control group (2), low-intensity exercise group (brisk walking, 57-63% maximum heart rate, 150 min/week, 12 months), and (3) moderate-intensity exercise group (jogging, 64-76% maximum heart rate, 150 min/week, 12 months). The three groups of subjects will receive the same health education and prohibition of high-purine diet during the intervention period. The primary outcomes will be SUA concentration, SUA concentration change (mg/dL), SUA change rate (%), and the proportion of HUA patients. Secondary outcomes will include anthropometric parameters (body weight, waist circumference, hip circumference, BMI); physiological indicators (blood pressure, grip, vital capacity, maximum oxygen); biochemical indicators (blood lipid, blood sugar, liver enzyme, creatinine, and blood urea nitrogen). Each group of patients will go through an assessment at baseline, 3rd, 6th, and 12th months.DiscussionThis study will evaluate the effect of 12-month low-intensity exercise and moderate-intensity exercise on HUA patients. We hypothesize that both low-intensity and moderate-intensity exercise would improve HUA as compared with no-exercise control, and that moderate-intensity exercise would be more effective than low-intensity exercise in improving HUA. These results can provide a basis for the current physical activity guidelines for HUA’s healthy lifestyle management.Ethics and DisseminationThis study has been approved by the Ethical Review Committee of the Shanghai University of Sport (approval number: 102772020RT005). Informed consent will be obtained from all participants or their guardians. The authors intend to submit the study findings to peer-reviewed journals or academic conferences to be published.Clinical Trial RegistrationChinese Clinical Trial Registry, identifier ChiCTR2100042643.

scholarly journals Feasibility of a Home-Based Task-Switching Training in Middle-Aged Caregivers

2022 ◽  
Author(s):  
Sarah Susanne Lütke Lanfer ◽  
Sören Enge ◽  
Marlen Melzer ◽  
Jürgen Wegge ◽  
Matthias Kliegel
Keyword(s):  
Task Switching ◽  
Real Life ◽  
Cognitive Tasks ◽  
Control Group ◽  
Laboratory Studies ◽  
Working Population ◽  
Middle Aged ◽  
Laboratory Findings ◽  
Home Based ◽  
Switching Task

AbstractThe current study aimed at investigating feasibility of a self-administered task-switching training in a middle-aged working population. Eighty-one caregivers (41–62 years old) were instructed to train at home 8 times either within a 7- or 14-day interval. Only 56.7% performed more than 50% of the instructed number of training sessions. However, compliant caregivers (who completed more than 4 training sessions) showed significant training gains and transfer to an untrained task-switching task. Although transfer effects to other cognitive tasks were not found, trained participants tended to report fewer everyday memory failures than a control group. In conclusion, the implementation of a home-based task-switching training in everyday life of caregivers is possible. However, there is only limited evidence for generalization of results of previous laboratory studies. Adherence and transfer to other cognitive tasks are discussed as important challenges in conveying laboratory findings into real life.

scholarly journals Effectiveness of a home-based exercise program on anthropometric and metabolic changes among school cooks

2015 ◽  
Vol 20 (12) ◽  
pp. 3943-3950 ◽  
Author(s):  
Mauro Felippe Felix Mediano ◽  
Rita Adriana Gomes de Souza ◽  
Amanda Moura Souza ◽  
Rosely Sichieri
Keyword(s):  
Weight Loss ◽  
Weight Control ◽  
Statistical Significance ◽  
Exercise Program ◽  
Exercise Group ◽  
Metabolic Changes ◽  
Moderate Intensity ◽  
Control Group ◽  
Low Intensity ◽  
Home Based

Abstract The scope of this study was to evaluate the anthropometric and metabolic changes after low intensity home-based exercise. In the school year of 2007, 95 school cooks in the city of Niteroi (State of Rio de Janeiro, Brazil) were randomly assigned to one of the following groups: home-based exercise (n = 47) or control group (n = 48). The home-based exercise program was performed three times a week, during 40 minutes at moderate intensity. Anthropometric variables were collected at the baseline and after 4 and 8 months, whereas biochemical and individual food intake were measured at the baseline and after 8 months. Energy expenditure was evaluated only at the baseline. The home-based exercise group exhibited a greater weight loss (-0.9 vs. -0.2; p = 0.05) in comparison with controls during the follow-up and the same pattern was found for BMI (-0.1 vs. +0.1; p = 0.07), although without statistical significance. Exercise showed no effects on waist circumference, lipid profile and glucose. In conclusion, greater weight loss was observed in the group that performed low intensity home-based exercise and this strategy can assist in body weight control even without alterations in terms of lipids and glucose.

Feasibility of an Exercise Program for Older Depressive Inpatients

GeroPsych ◽  
2015 ◽  
Vol 28 (4) ◽  
pp. 163-171 ◽  
Author(s):  
Andreas Heissel ◽  
Anou Vesterling ◽  
Stephanie A. White ◽  
Gunnar Kallies ◽  
Diana Behr ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Pilot Trial ◽  
Exercise Program ◽  
Exercise Group ◽  
Neurocognitive Functioning ◽  
Control Group ◽  
Active Control Group ◽  
Major Depressive ◽  
Older Inpatients ◽  
Relaxation Exercises

Abstract. Twelve older inpatients (M age = 66.8) with Major Depressive Disorder (MDD) participated in this controlled pilot trial either in a physical exercise group (PEG; n = 6; aerobic, strength, and coordination exercises) or an active control group (ACG; n = 6; relaxation exercises) twice a week for four weeks. While depressive symptoms decreased in both groups, reduction of symptoms was significantly larger in the PEG. However, the PEG had higher BDI scores compared to the ACG at pretest. Neurocognitive functioning and brain-derived neurotrophic factor (BDNF) concentration did not change significantly. A four-week exercise program may be a feasible adjunct therapy in older MDD patients but the efficacy of the program needs to be proven with larger samples.

Differences in Suicidal Thoughts and Behaviors Among Three Racial Groups

Crisis ◽  
2020 ◽  
Vol 41 (3) ◽  
pp. 172-178
Author(s):  
Brooke A. Ammerman ◽  
Martha K. Fahlgren ◽  
Kristen M. Sorgi ◽  
Michael S. McCloskey
Keyword(s):  
Suicide Attempts ◽  
Health Concern ◽  
Future Research ◽  
Racial Groups ◽  
Contributing Factors ◽  
Suicidal Thoughts ◽  
Final Sample ◽  
And Behaviors ◽  
Assessment Procedures ◽  
Suicidal Thoughts And Behaviors

Abstract. Background: Despite being a major public health concern, it is unclear how suicidal thoughts and behaviors differentially impact separate racial groups. Aims: The aim of the current study was to examine the occurrence of nonlethal suicide events, in addition to suicide attempt characteristics and factors contributing to suicide attempts. Method: A final sample of 7,094 undergraduates from a large northeastern university, identifying as members of three racial groups (White [67.30%], Black [17.30%], and Asian [15.40%]), completed online questionnaires. Results: White participants reported increased likelihood of endorsing lifetime suicidal ideation and plan, whereas Black participants reported decreased likelihood of these events; no differences were found in rates of lifetime suicide attempts. Black participants' suicidal behavior may involve greater ambivalence of intent. A higher proportion of Asian participants endorsed interpersonal factors as contributing to their suicide attempts, whereas a greater percentage of White participants reported internal contributing factors. Limitations: Findings are limited by the sample size and assessment of lifetime suicidal thoughts and behaviors. Conclusion: The findings present a more nuanced look at attitudes and actions related to suicidal thoughts and behaviors that may inform future research and risk assessment procedures.

Effect of Early Low-Intensity Exercise on Rat Hind-Limb Muscles Following Acute Ischemic Stroke

2006 ◽  
Vol 7 (3) ◽  
pp. 163-174 ◽  
Author(s):  
Myoung-Ae Choe ◽  
Gyeong Ju An ◽  
Yoon-Kyong Lee ◽  
Ji Hye Im ◽  
Smi Choi-Kwon ◽  
...  
Keyword(s):  
Hind Limb ◽  
Gastrocnemius Muscle ◽  
Exercise Group ◽  
Cross Sectional Area ◽  
Type I ◽  
Sectional Area ◽  
Muscle Type ◽  
Cross Sectional ◽  
Low Intensity ◽  
Low Intensity Exercise

This study examined the effects of daily low-intensity exercise following acute stroke on mass, Type I and II fiber cross-sectional area, and myofibrillar protein content of hind-limb muscles in a rat model. Adult male Sprague-Dawley rats were randomly assigned to 1 of 4 groups (n = 7-9 per group): stroke (occlusion of the right middle cerebral artery [RMCA]), control (sham RMCA procedure), exercise, and stroke-exercise. Beginning 48 hours post-stroke induction/sham operation, rats in the exercise group had 6 sessions of exercise in which they ran on a treadmill at grade 10 for 20 min/day at 10 m/min. At 8 days poststroke, all rats were anesthetized and soleus, plantaris, and gastrocnemius muscles were dissected from both the affected and unaffected sides. After 6 sessions of exercise following acute ischemic stroke, the stroke-exercise group showed the following significant (p < .05) increases compared to the stroke-only group: body weight and dietary intake, muscle weight of affected soleus and both affected and unaffected gastrocnemius muscle, Type I fiber cross-sectional area of affected soleus and both affected and unaffected gastrocnemius muscle, Type II fiber cross-sectional area of the unaffected soleus, both affected and unaffected plantaris and gastrocnemius muscle, Type II fiber distribution of affected gastrocnemius muscle, and myofibrillar protein content of both affected and unaffected soleus muscle. Daily low-intensity exercise following acute stroke attenuates hind-limb muscle atrophy in both affected and unaffected sides. The effects of exercise are more pronounced in the soleus and gastrocnemius as compared to the plantaris muscle.

Motorcyclist injury risk as a function of real-life crash speed and other contributing factors

2019 ◽  
Vol 123 ◽  
pp. 374-386 ◽  
Author(s):  
Chengkai Ding ◽  
Matteo Rizzi ◽  
Johan Strandroth ◽  
Ulrich Sander ◽  
Nils Lubbe
Keyword(s):  
Injury Risk ◽  
Real Life ◽  
Contributing Factors

scholarly journals Pediatric Residents and Interns in an Italian Hospital Perform Improved Bibliographic Searches when Assisted by a Biomedical Librarian

2013 ◽  
Vol 8 (1) ◽  
pp. 76
Author(s):  
Mathew Stone
Keyword(s):  
Teaching Hospital ◽  
Assessment Tool ◽  
Controlled Trial ◽  
Intervention Group ◽  
Real Life ◽  
Boolean Logic ◽  
Bibliographic Databases ◽  
Control Group ◽  
Pediatric Residents ◽  
Clinical Scenarios

A Review of: Gardois, P., Calabrese, R., Colombi, N., Lingua, C., Longo, F., Villanacci, M., Miniero, R., & Piga, A. (2011). Effectiveness of bibliographic searches performed by paediatric residents and interns assisted by librarian. A randomised controlled trial. Health Information and Libraries Journal, 28(4), 273-284. doi: 10.1111/j.1471-1842.2011.00957.x Objective – To establish whether the assistance of an experienced biomedical librarian delivers an improvement in the searching of bibliographic databases as performed by medical residents and interns. Design – Randomized controlled trial. Setting – The pediatrics department of a large Italian teaching hospital. Subjects – 18 pediatric residents and interns. Methods – 23 residents and interns from the pediatrics department of a large Italian teaching hospital were invited to participate in this study, of which 18 agreed. Subjects were then randomized into two groups and asked to spend between 30 and 90 minutes searching bibliographic databases for evidence to answer a real-life clinical question which was randomly allocated to them. Each member of the intervention group was provided with an experienced biomedical librarian to provide assistance throughout the search session. The control group received no assistance. The outcome of the search was then measured using an assessment tool adapted for the purpose of this study from the Fresno test of competence in evidence based medicine. This adapted assessment tool rated the “global success” of the search and included criteria such as appropriate question formulation, number of PICO terms translated into search terms, use of Boolean logic, use of subject headings, use of filters, use of limits, and the percentage of citations retrieved that matched a gold standard set of citations found in a prior search by two librarians (who were not involved in assisting the subjects) together with an expert clinician. Main Results – The intervention group scored a median average of 73.6 points out of a possible 100, compared with the control group which scored 50.4. The difference of 23.2 points in favour of the librarian assisted group was a statistically significant result (p value = 0.013) with a 95% confidence interval of between 4.8 and 33.2. Conclusion – This study presents credible evidence that assistance provided by an experienced biomedical librarian improves the quality of the bibliographic database searches performed by residents and interns using real-life clinical scenarios.

scholarly journals Exercise Ameliorates Spinal Cord Injury by Changing DNA Methylation

Cells ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 143
Author(s):  
Ganchimeg Davaa ◽  
Jin Young Hong ◽  
Tae Uk Kim ◽  
Seong Jae Lee ◽  
Seo Young Kim ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Motor Cortex ◽  
Functional Recovery ◽  
Treadmill Exercise ◽  
Exercise Group ◽  
Control Group ◽  
Epigenetic Changes ◽  
Cord Injury ◽  
The Brain

Exercise training is a traditional method to maximize remaining function in patients with spinal cord injury (SCI), but the exact mechanism by which exercise promotes recovery after SCI has not been identified; whether exercise truly has a beneficial effect on SCI also remains unclear. Previously, we showed that epigenetic changes in the brain motor cortex occur after SCI and that a treatment leading to epigenetic modulation effectively promotes functional recovery after SCI. We aimed to determine how exercise induces functional improvement in rats subjected to SCI and whether epigenetic changes are engaged in the effects of exercise. A spinal cord contusion model was established in rats, which were then subjected to treadmill exercise for 12 weeks. We found that the size of the lesion cavity and the number of macrophages were decreased more in the exercise group than in the control group after 12 weeks of injury. Immunofluorescence and DNA dot blot analysis revealed that levels of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) in the brain motor cortex were increased after exercise. Accordingly, the expression of ten-eleven translocation (Tet) family members (Tet1, Tet2, and Tet3) in the brain motor cortex also elevated. However, no macrophage polarization was induced by exercise. Locomotor function, including Basso, Beattie, and Bresnahan (BBB) and ladder scores, also improved in the exercise group compared to the control group. We concluded that treadmill exercise facilitates functional recovery in rats with SCI, and mechanistically epigenetic changes in the brain motor cortex may contribute to exercise-induced improvements.

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