scholarly journals Observation on the Effect of Local Flap Transfer and Sclera Transplantation in Repairing Skin Defect after Eyelid Tumor Operation

2020 ◽  
Vol 4 (1) ◽  
pp. 28-31
Author(s):  
Ying-Hui Ma ◽  
Gang Liu ◽  
Jie Yang

Introduction: Eyelid tumor refers to the primary eyelid skin and accessory tumors, which not only affects the appearance and vision, and even local infiltration and distant metastasis, thereby threatening life. Surgical resection is the most important and effective treatment, but tumor resection often leads to a wide range of eyelid defects, significantly affecting the shape and function of the eyelid. Therefore, the eyelid defect must be repaired after resection to achieve the purpose of aesthetic appearance and protection of the eyeball. The objective of the study was to analyze the clinical results of local flap transfer and scleral transplantation in repairing skin defect after eyelid tumor operation. Methods: Forty patients with postoperative skin defects of eyelid tumors admitted from December 2008 to December 2018 were taken for analysis and divided into two groups, 20 cases in each group. The control group underwent autologous lip mucous membrane transfer and nearby skin flap, while the experimental group received local skin flap rotation and scleral allograft repair. The clinical effect of repair of the two groups were compared. Results: In the experimental group, the effect of clinical repairs were better, the difference of height of palpebralfissure and the length of palpebral fissure were compared with the control group, which showed statistical significance favoring the experimental group. Conclusion: Local flap transfer and scleral transplantation has better clinical outcome to repair the skin defect after operation of eyelid tumor.

2019 ◽  
Vol 25 (10) ◽  
pp. 1601-1623
Author(s):  
Sandeep W. Dahake ◽  
Abhaykumar M. Kuthe ◽  
Mahesh B. Mawale

Purpose This study aims to find the usefulness of the customized surgical osteotomy guide (CSOG) for accurate mandibular tumor resection for boosting the accuracy of prefabricated customized implant fixation in mandibular reconstructions. Design/methodology/approach In all, 30 diseased mandibular RP models (biomodels) were allocated for the study (for experimental group [n = 15] and for control group [n = 15]). To reconstruct the mandible with customized implant in the experimental group, CSOGs and in control group, no CSOG were used for accurate tumor resections. In control group, only preoperative virtual surgical planning (VSP) and reconstructed RP mandible model were used for the reference. Individually each patient’s preoperative mandibular reconstructions data of both the groups were superimposed to the preoperative VSP of respective patient by registering images with the non-surgical side of the mandible. In both the groups, 3D measurements were taken on the reconstructed side and compared the preoperative VSP and postoperative reconstructed mandible data. The sum of the differences between pre and postoperative data was considered as the total error. This procedure was followed for both the groups and compared the obtained error between the two groups using statistical analysis. Findings The use of CSOG for accurate tumor resection and exact implant fixation in mandibular reconstruction produced a smaller total error than without using CSOG. Originality/value The results showed that, benefits provided with the use of CSOG in mandibular reconstruction justified its use over the without using CSOG, even in free hand tumor resection using rotating burr.


Author(s):  
Bambang Setiawan ◽  
M. Solehuddin ◽  
Anne Hafina

Triggered by the importance of self-regulation, then this research was conducted in order to test the effectiveness of group guidance with self-instruction technique in order to enhance self-regulation of the students. Self-regulation is considered as the As card of human personality as it is assumed to be able to strenghten and increase the ability of a person to face the demand of live as well as act as a guide of behaviours of the person himself. In addition, lack of self-regulation will also cause wide range of problems specifically for the students as it may affect the academic achivement of the students themselves. Quantitative approach with quasy-experimental design was used in this research. Meanwhile, the research method used was Nonequivalent Pretest-Posttest Control Group Design. The selection of the sample of the study was by using the purposive sampling technique, the total samples taken were 69 students, 39 students were placed in experimental group and other 30 students were in control group. The study found that in general the profile of the students’ self-regulation was on the moderate category, and empirically the group guidance with self-instruction technique was proven to be able to enhance students’ self-regulation.  


2018 ◽  
Vol 48 (4) ◽  
pp. 495-512
Author(s):  
Daphne Tan ◽  
Frank M. Diaz ◽  
Peter Miksza

Previous research suggests that musicians modulate a predictable set of acoustic cues to convey distinct emotions. The current study focuses on singers, testing the validity of cues previously reported for a wide range of instruments. The study also asks: What effect might a musician’s mindfulness have on their expressive performance? Two groups of highly skilled vocalists recorded performances of a novel melody with four distinct emotions. Prior to the performance task, an experimental group took part in a guided mindfulness induction, while a control group engaged in a self-selected relaxation activity; state mindfulness was assessed immediately after. Recordings were analyzed for tempo, temporal variation, intensity, mean centroid, vibrato rate, vibrato extent, and attack slope; individual notes with particular scale-degree functions were also compared. Results show that the two groups of participants had similar cue usage, although those in the experimental condition had higher mindfulness scores and attributed improvements in focus and awareness to the induction task. Participants as a whole used cues in the predicted directions, and significant differences were found on all acoustical measures, except vibrato rate, as a function of expressed emotion. Results also indicate that participants modified intonation to distinguish between positive and negative emotions.


2021 ◽  
Vol 37 (3) ◽  
Author(s):  
Xin Li ◽  
Zhen-jie Liu ◽  
Liang Liang ◽  
Hai-qing Dong

Objective: To observe application values of intraoperative ultrasound combined with neuro electrophysiological detection in the spinal cord glioma surgery. Methods: Sixty patients with spinal cord glioma hospitalized in Baoding First Central Hospital from January 2016 to January 2018 were selected, randomly divided into two groups by the random number table method, with 30 cases of each group. PASS software was used to calculate the sample size. The control group was treated with traditional microsurgery, while the experimental group was treated with intraoperative ultrasound combined with neuro electrophysiological testing. The operation time, intraoperative blood loss, postoperative hospital stays, degree of tumor resection, clinical efficacy, recovery of neurological function, recovery of health status, quality of life score, and 2-year recurrence rate of the two groups of patients were observed and compared. Results: The operation time of the experimental group was longer than that of the control group, and the postoperative hospital stay was shorter than that of the control group. The complete tumor resection rate, complete remission rate and postoperative scale scores of the experimental group were significantly higher than those of the control group, while the recurrence rate within two years was significantly lower than that of the control group. The above differences were statistically significant (p<0.05). Conclusions: Intraoperative ultrasound combined with neuro-electrophysiological detection for spinal glioma has more adequate protection of nerve function, high clinical complete remission rate, more thorough tumor resection, and lower recurrence rate than traditional microsurgery, which is worthy of clinical application. doi: https://doi.org/10.12669/pjms.37.3.3638 How to cite this:Li X, Liu ZJ, Liang L, Dong HQ. Application evaluation of intraoperative ultrasound combined with neuro electrophysiological detection in the spinal cord glioma surgery. Pak J Med Sci. 2021;37(3):---------. doi: https://doi.org/10.12669/pjms.37.3.3638 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Author(s):  
P. Mayilshami ◽  
U. Pandian

The present day students are in a digital era of learning. During their course of study they acquire a wide range of information from various sources like Internet, books and journals. They came into contact with worldwide friends using Twitter, Face book and Google Groups etc. The researcher observed that the students face many problems on learning the subject; Commerce, especially advertising, because of its vague and critical nature. Majority of the content in the said subject are in advertising which develops unwanted boredom in the minds of the students. If it is taught with the help of software packages, the teacher can explain the learning more interesting and meaningful. The investigator intends to prepare a multimedia package using video lessons and animation covering the commerce subject and it’s tested on the students of experimental group and compared with the control group whom were taught chalk and talk method. The study proved that The control and experimental post-test group students differ in their achievement of commerce. The students in the experimental group are better in their commerce achievement than the Control group.


2012 ◽  
Vol 24 (03) ◽  
pp. 237-244 ◽  
Author(s):  
Yu-Lin Zhang ◽  
Shu-Dong Wang ◽  
Long-Xiao Sun ◽  
Yuan-Yuan Zhang ◽  
Da-Zhi Meng

Gene networks research has grown steadily because of its potential to represent, characterize and model a wide range of systems and phenomena on the molecular level. Especially the studies on the cancer-related gene networks through complex interactions can help to provide better understanding of the formation and development of cancer. In this work, using the expressions data of normal and lung adenocarcinoma stage, mutual information networks of cancer-related genes are constructed first. Then a model for cascading failures with DNA repair function of weighted gene networks is built. Furthermore, comparisons of numerical experiments show that deleting nodes in the networks of adenocarcinoma experimental group is more likely to cause larger scales of cascading failure than the one of control group. In addition, we find that 13 genes of control group and 12 genes of experimental group are of very strong destructibility for the two networks, respectively. The failures of these genes can lead to the paralysis of the whole network. Therefore, we conclude that these genes might play important roles in keeping normal level or developing lung adenocarcinoma of organisms. The results may have certain significance for the interpretation of lung cancer development and provide beneficial inspirations to clarify lung cancer occurrence of biological mechanism.


2019 ◽  
Vol 16 (Number 2) ◽  
pp. 187-200
Author(s):  
Abdo Mohamed Al-Mekhlafi ◽  
Mohamed El Tahir Osman

Purpose - This study examined the impact of a holistic school improvement model on overall school effectiveness, More specifically, it attempted to answer two questions: 1) Are there any significant differences in school performance between the control group and the experimental group before and after the experiment? 2) Is there any significant improvement in the experimental group school effectiveness before and after the experiment? Methodology - As a part of a four-year longitudinal research project, the study used a quasi experimental research design to examine the impact of a holistic school improvement model on enhancing overall school effectiveness in Oman. The sample consisted of 16 intact classes selected from 8 schools (4 experimental and 4 control groups), with a total of 2378 students (1157 from grade nine classes and 1221 from grade seven classes). The experimental group schools were exposed to a wide range of school improvement activities within a four-year period. A series of workshops on activating the 13 elements of the Innovation Sustainability Wheel (ISW) were delivered to all administrators and teachers at the target experimental group schools, in addition to empowering students through enrichment programs in five subject areas. Data was collected from the Omani Ministry of Education school performance indicators, which included five subject matter achievement tests aggregated over three years. Findings - The study revealed significant differences in overall school performance across the four years between the control and experimental schools, in favour of the experimental group. Moreover, a significant progression of school effectiveness was observed in the two grade levels of the experimental group. Significance - The findings are significant in terms of providing educational systems with a workable mechanism for identifying key areas of weaknesses and means of improvement; establishing a chain of actions for activating all interrelated elements that act as driving forces for sustainable change; ensuring that the indicators of school improvement should include both operational processes and students’ learning outcomes; and contributing to the knowledge base in the area of school improvement in terms of a research-based model that has potential implications for practitioners and policy makers.


2019 ◽  
Vol 21 (94) ◽  
pp. 92-96 ◽  
Author(s):  
Y. Y. Lavryshyn ◽  
B. V. Gutyj

The article presents the results of studies on the influence of cadmium load on the body of young cattle. The adverse effect of Cadmium on the liver causes a wide range of pathological changes at various levels of its organization. The purpose of the work was to investigate protein synthesize function on the liver of bulls for experimental chronic cadmium toxicity. The research was carried out on the basis of a farm at the village Ivanivtsi, Zhydachiv district of Lviv region, on 10 bulls of six months old, Ukrainian black-and-white milk breed, which were formed in 2 groups of 5 animals in each: control and experimental. Bulls of the control group were in the usual diet. Bulls of the experimental group were fed with forage with cadmium chloride at a dose of 0.04 mg/kg body weight of the animal. The research lasted for 30 days. Protein synthesize function of the liver was determined by the level of serum total protein and protein fractions. It was established that when feeding cows with feed of cadmium chloride in a dose of 0.04 mg/kg of body weight of an animal for 30 days in animals suppressed protein synthesize function of the liver, which manifests itself by lowering the total protein of blood. It reached the lowest level at the 20th day of the experiment, where, accordingly, it fluctuated within the limits of 61.9 ± 1.14 g/l. Reducing the level of total protein in the blood of the bulls of the experimental group under cadmium loading was due to lowering the level of albumin. At day 20 of the experiment, the level of albumin in the blood of animals in the experimental group decreased by 16.5%. On the background of general hypoproteinemia there is a significant imbalance between albumins and globulins in serum of diseased animals. It was established that the level of globulins increased in the blood of Bulls, which were under cadmium load. Increasing the level of globulins in blood serum of bulls reflects the intensity of inflammatory processes in their body for cadmium loading.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Yongxiang Yan ◽  
Jianwei Luo ◽  
Liuming Pei ◽  
Jianfeng Zeng ◽  
Wenchan Yan ◽  
...  

Objective. To study the effect of a care bundle combined with continuous positive airway pressure (CPAP) in the postanesthesia care unit (PACU) on rapid recovery after pulmonary tumor resection. Methods. A total of 135 patients requiring anesthesia resuscitation after pulmonary tumor resection in our hospital from June 2020 to February 2021 were selected. They were randomly divided into three groups: the PACU experimental group, PACU control group, and operating room resuscitation (OR) group. Subsequently, their intraoperative clinical symptoms, parameters in monitoring postoperative respiratory status, and follow-up results were compared among the three groups. Results. The PACU experimental group had the highest number of right lesions, while the OR group had the highest intraoperative blood transfusion volume, urine volume, intraoperative colloid volume, intrapulmonary shunt, and intraoperative physician handover rate ( P < 0.05 ). Before surgery, serum potassium (K) in the PACU experimental group was significantly higher than that in the OR group but lower than that in the PACU control group ( P < 0.01 ). During the time in the PACU, blood partial pressure of oxygen (PO2) and oxygen index (OI) levels in the PACU experimental group were significantly higher than those in the other groups ( P < 0.01 ). After surgery, total PACU stay time, time from PACU to extubation, and stay after extubation were markedly reduced in the PACU experimental group ( P < 0.05 ). The highest number of patients with drainage was found in the PACU experimental group, while the highest number of patients without drainage was found in the PACU control group. Conclusion. A care bundle combined with CPAP in the PACU can improve the monitoring time of respiratory status and improve blood gas parameters, thus accelerating the postoperative rehabilitation process of patients undergoing pulmonary tumor resection.


2020 ◽  
Vol 3 (2) ◽  
pp. 47-52
Author(s):  
Y. Y. Lavryshyn ◽  
B. V. Gutyj ◽  
K. Y. Leskiv ◽  
I. I. Hariv ◽  
L. H. Yevtukh ◽  
...  

The article presents the results of research on the effect of cadmium load on the body of young cattle. The negative effect of Cadmium on the liver causes a wide range of pathological changes at different levels of its organization. The impact of heavy metals on the immune system is particularly significant, because it performs a leading role in maintaining health and is recognized as one of the most sensitive to adverse factors, even in relatively low concentrations. The aim of the study was to investigate the influence of cadmium on the cellular part of the immune system of young cattle. The research was carried out on 10 bulls of six months of age, Ukrainian black-and-white dairy breed, which were formed into 2 groups of 5 animals each: control and experimental. The bulls of the control group were on a normal diet. Animals of the experimental group were administered cadmium chloride at a dose of 0.04 mg/kg body weight of the animal. It was found that feeding bulls with a diet of cadmium chloride, the number of B-lymphocytes on the 5th day of the experiment was 17.54 ± 0.95 %. The lowest number of B-lymphocytes was on the 20th day of testing – 15.12 ± 0.37 %. The study of the number of T-lymphocytes shows that at the beginning of analysis the number of T-lymphocytes in the blood of animals of the control and experimental groups ranged from 40.70 ± 3.62 and 40.85 ± 2.54 %. Subsequently, the number of T-lymphocytes in the blood of the experimental group began to decline. The lowest number of T-lymphocytes was in the experimental group of animals on the 20th day of the research, compared with the control group, this figure decreased by 3.63 %. The state of immunity of animals under cadmium load significantly depends on the ratio of T-helpers to T-suppressors. It was found that the immunoregulatory index of blood of bulls of the experimental group probably decreased from 10 days of the research. The number of T-helper lymphocytes in the blood of the experimental group of bulls under cadmium loading is probably reduced by 15, 20 and 30 days of testing. A probable increase in the number of T-suppressors was noted in the bull's blood of the experimental group on the 20th day of the research. Immunoglobulins of different classes are crucial among bull’s serum proteins under cadmium loading. The concentration of immunoglobulins in the blood under cadmium load decreased by 15.9 % relative to the control group on the 20th day of analysis.


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