scholarly journals Investigating the impact of structural factors upon that/zero complementizer alternation patterns in verbs of cognition: a diachronic corpus-based multifactorial analysis

2018 ◽  
pp. 83-112
Author(s):  
Christopher Shank ◽  
Koen Plevoets
Keyword(s):  
Predictive Power ◽  
Structural Features ◽  
Stepwise Logistic Regression ◽  
Large Set ◽  
Structural Factors ◽  
Quantitative Methodology ◽  
Stepwise Logistic Regression Analysis ◽  
Conditioning Factors ◽  
The Impact ◽  
Over Time

This corpus-based study examines the diachronic development of the that/zero alternation with nine verbs of cognition, viz. think, believe, feel, guess, imagine, know, realize, suppose and understand by means of a stepwise logistic regression analysis. The data comprised a total of (n=5,812) think, (n=3,056) believe, (n=1,273) feel, (n=1,885) guess, (n=2,225) imagine, (n=1,805) know, (n=1,244) realize, (n=2,836) suppose and (n=3,395) understand tokens from both spoken and written corpora from 1580–2012. Taking our cue from previous research suggesting that there has been a diachronic increase in the use of the zero complementizer form from Late Middle / Early Modern to Present-day English, we use a large set of parallel spoken and written diachronic data and a rigorous quantitative methodology to test this claim with the nine aforementioned verbs. In addition, we also investigate the impact of eleven structural features, which have been claimed to act as predictors for the use or presence of the zero complementizer form for ‘panchronic’ (i.e. effects are aggregated over all time periods) and diachronic effects. The objectives of this study are to examine the following: (i) whether there is indeed a diachronic trend towards more zero use; (ii) whether the conditioning factors proposed in the literature indeed predict the zero form; (iii) to what extent these factors interact; and (iv) whether the predictive power of the conditioning factors becomes stronger or weaker over time. The analysis shows that, contrary to the aforementioned belief that the zero form has been on the increase, there is in fact a steady decrease in zero use, but the extent of this decrease is not the same for all verbs. In addition, the analysis of interactions with verb type indicates differences between verbs in terms of the predictive power of the conditioning factors. Additional significant interactions emerged, notably with verb, mode (i.e. spoken or written data) and period. The interactions with period show that certain factors that are good predictors of the zero form overall lose predictive power over time.

scholarly journals Evaluating polymer interplay after hot water pretreatment to investigate maize stem internode recalcitrance

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Amandine Leroy ◽  
Xavier Falourd ◽  
Loïc Foucat ◽  
Valérie Méchin ◽  
Fabienne Guillon ◽  
...  
Keyword(s):  
Cell Wall ◽  
Negative Impact ◽  
Lignin Content ◽  
Structural Features ◽  
Hot Water ◽  
Condensed State ◽  
Structural Factors ◽  
Water Pretreatment ◽  
Hot Water Pretreatment ◽  
The Impact

Abstract Background Biomass recalcitrance is governed by various molecular and structural factors but the interplay between these multiscale factors remains unclear. In this study, hot water pretreatment (HWP) was applied to maize stem internodes to highlight the impact of the ultrastructure of the polymers and their interactions on the accessibility and recalcitrance of the lignocellulosic biomass. The impact of HWP was analysed at different scales, from the polymer ultrastructure or water mobility to the cell wall organisation by combining complementary compositional, spectral and NMR analyses. Results HWP increased the kinetics and yield of saccharification. Chemical characterisation showed that HWP altered cell wall composition with a loss of hemicelluloses (up to 45% in the 40-min HWP) and of ferulic acid cross-linking associated with lignin enrichment. The lignin structure was also altered (up to 35% reduction in β–O–4 bonds), associated with slight depolymerisation/repolymerisation depending on the length of treatment. The increase in $${T}_{1\rho }^{H}$$ T 1 ρ H , $${T}_{HH}$$ T HH and specific surface area (SSA) showed that the cellulose environment was looser after pretreatment. These changes were linked to the increased accessibility of more constrained water to the cellulose in the 5–15 nm pore size range. Conclusion The loss of hemicelluloses and changes in polymer structural features caused by HWP led to reorganisation of the lignocellulose matrix. These modifications increased the SSA and redistributed the water thereby increasing the accessibility of cellulases and enhancing hydrolysis. Interestingly, lignin content did not have a negative impact on enzymatic hydrolysis but a higher lignin condensed state appeared to promote saccharification. The environment and organisation of lignin is thus more important than its concentration in explaining cellulose accessibility. Elucidating the interactions between polymers is the key to understanding LB recalcitrance and to identifying the best severity conditions to optimise HWP in sustainable biorefineries.

scholarly journals The Impact of Syringe Services Program Policy on Risk Behaviors Among Persons Who Inject Drugs in 3 US Cities, 2005-2015

2020 ◽  
Vol 135 (1_suppl) ◽  
pp. 138S-148S
Author(s):  
Tanner Nassau ◽  
Alia Al-Tayyib ◽  
William T. Robinson ◽  
Jennifer Shinefield ◽  
Kathleen A. Brady
Keyword(s):  
New Orleans ◽  
Risk Behaviors ◽  
Syringe Sharing ◽  
Stepwise Logistic Regression ◽  
Stepwise Logistic Regression Analysis ◽  
Persons Who Inject Drugs ◽  
National Hiv Behavioral Surveillance ◽  
Program Policy ◽  
The Impact ◽  
Us Cities

Objectives The impact of a syringe services program (SSP) policy on risk behaviors and its durability are not as well studied as the impact of the SSPs themselves. We examined whether trends in syringe sharing among persons who inject drugs (PWID) were associated with changes to syringe access policies in 3 US cities: Denver, New Orleans, and Philadelphia. Methods PWID were surveyed through National HIV Behavioral Surveillance System surveys in each city in 2005, 2009, 2012, and 2015. We assessed changes in syringe sharing from 2005 to 2015 by city. We used multivariable stepwise logistic regression analysis to measure the associations among syringe sharing and injection works sharing, time, and SSP access. Results From 2005 to 2015, syringe sharing decreased significantly from 49.1% to 33.1% in Denver ( P < .001), increased significantly from 32.0% to 50.5% in New Orleans ( P < .001), and remained unchanged in Philadelphia (30.4% to 31.5%; P = .87). Compared with persons who obtained syringes from any nonsterile source, the adjusted odds of syringe sharing among PWID were significantly lower in each city if syringes were obtained from sterile sources only: Denver adjusted odds ratio (aOR) = 0.23 (95% confidence interval [CI], 0.18-0.30; New Orleans aOR = 0.26 (95% CI, 0.19-0.35), and Philadelphia aOR = 0.43 (95% CI, 0.33-0.57). Conclusions The lowest proportion of PWID reporting syringe sharing was in Philadelphia, which has a long-standing legal SSP. Implementation of a legal SSP in Denver in 2012 corresponded to a decrease in sharing, whereas the lack of a legal SSP in New Orleans corresponded to an increase in sharing. Universal long-term access to legal SSPs could further the progress made in HIV prevention among PWID.

Risk Factors for Delirium in Trauma Patients: The Impact of Ethanol Use and Lack of Insurance

2011 ◽  
Vol 77 (5) ◽  
pp. 621-626 ◽  
Author(s):  
Bernardino C. Branco ◽  
Kenji Inaba ◽  
Marko Bukur ◽  
Peep Talving ◽  
Matthew Oliver ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Logistic Regression ◽  
Chronic Ethanol ◽  
Ethanol Ingestion ◽  
Stepwise Logistic Regression ◽  
Trauma Patients ◽  
Stepwise Logistic Regression Analysis ◽  
Independent Risk Factors ◽  
The Impact

The purpose of this study was to examine independent risk factors, and in particular the impact of alcohol on the development of delirium, in a cohort of trauma patients screened for ethanol ingestion on admission to hospital. The National Trauma Databank (v. 7.0) was used to identify all patients 18 years or older screened for ethanol on admission. Patients who developed delirium were compared with those who did not. Stepwise logistic regression analysis was used to identify independent risk factors for the development of delirium. A total of 504,839 patients with admission ethanol levels were identified. Of those, 2,909 (0.6%) developed delirium. Patients developing delirium were significantly older, more frequently male, and more likely to sustain thermal injuries and falls. Patients developing delirium had more comorbidities including chronic ethanol use (19.1% vs 4.5%, P < 0.001) and cardiovascular disease (21.5% vs 12.2%, P < 0.001). On admission, patients developing delirium were more likely to be intoxicated with ethanol (55.4% vs 26.5%, P < 0.001) and were more likely to be uninsured (17.8% vs 0.9%, P < 0.001). A stepwise logistic regression model identified lack of insurance, positive ethanol on admission, chronic ethanol use, Intensive Care Unit admission, age ≥ 55 years, burns, Medicare insurance, falls, and history of cardiovascular disease as independent risk factors for the development of delirium. The incidence of delirium in this trauma patient cohort was 0.6 per cent. The above risk factors were independently associated with the development of delirium. This data may be helpful in designing interventions to prevent delirium.

scholarly journals The Relationship Democracy with Health and Governance Indicators: Panel Probit Approach

2021 ◽  
Author(s):  
Tuğçe Acar ◽  
Ebru Çağlayan Akay
Keyword(s):  
Freedom Of Expression ◽  
Political Stability ◽  
Probit Analysis ◽  
Infant Mortality Rate ◽  
Structural Factors ◽  
Explanatory Variables ◽  
Governance Indicators ◽  
The Impact ◽  
The Relationship ◽  
Over Time

The relationship of politics with health has been documented in Greece and Rome in ancient times and has been the center of attention from past to present. The difficulty of interpreting the causal relationships between politics and democracy and outcome measures as the macro-social determinants of population health has limited the studies in the field. On the other hand, in the state-society relationship, governance and indicators representing the traditions and institutions in which authority is applied in a country are used as a tool to evaluate the tendencies of countries in the field of democracy over time. Accordingly, the study aims to address the issue in the relationship between democracy and health, together with governance indicators, within the framework of broader structural factors. For this aim, panel probit analysis was carried out for 144 countries between 2010 and 2018, examining the effect of explanatory variables on the probability of occurrence of the dependent variable. The limited number of studies dealing with the impact of democracy studies on the international level and over time makes the method used advantageous. According to the findings, the variables of freedom of expression and accountability, political stability and regulatory quality, which are among the indicators of governance, were found to be statistically significant on the democracy index, along with the variables of domestic general government health expenditures, infant mortality rate, GDP per capita, and the reasons for the results obtained were discussed.

scholarly journals Intraoperative magnesium infusion during carotid endarterectomy: a double-blind placebo-controlled trial

2009 ◽  
Vol 110 (5) ◽  
pp. 961-967 ◽  
Author(s):  
William J. Mack ◽  
Christopher P. Kellner ◽  
Daniel H. Sahlein ◽  
Andrew F. Ducruet ◽  
Grace H. Kim ◽  
...  
Keyword(s):  
Carotid Endarterectomy ◽  
Low Dose ◽  
Controlled Trial ◽  
Control Group ◽  
Stepwise Logistic Regression ◽  
High Dose ◽  
Stepwise Logistic Regression Analysis ◽  
Intravenous Magnesium ◽  
The Impact ◽  
Magnesium Therapy

Object Recent data from both experimental and clinical studies have supported the use of intravenous magnesium as a potential therapy in the setting of cerebral ischemia. This study assessed whether intraoperative magnesium therapy improves neuropsychometric testing (NPT) following carotid endarterectomy (CEA). Methods One hundred eight patients undergoing CEA were randomly assigned to receive placebo infusion or 1 of 3 magnesium-dosing protocols. Neuropsychometric testing was performed 1 day after surgery and compared with baseline performance. Assessment was also performed on a set of 35 patients concurrently undergoing lumbar laminectomy to serve as a control group for NPT. A forward stepwise logistic regression analysis was performed to evaluate the impact of magnesium therapy on NPT. A subgroup analysis was then performed, analyzing the impact of each intraoperative dose on NPT. Results Patients treated with intravenous magnesium infusion demonstrated less postoperative neurocognitive impairment than those treated with placebo (OR 0.27, 95% CI 0.10–0.74, p = 0.01). When stratified according to dosing bolus and intraoperative magnesium level, those who were treated with low-dose magnesium had less cognitive decline than those treated with placebo (OR 0.09, 95% CI 0.02–0.50, p < 0.01). Those in the high-dose magnesium group demonstrated no difference from the placebo-treated group. Conclusions Low-dose intraoperative magnesium therapy protects against neurocognitive decline following CEA.

scholarly journals Leadership in Educational

2020 ◽  
pp. 85-96
Author(s):  
Mehmet Toprak
Keyword(s):  
Teacher Leadership ◽  
Future Research ◽  
Quantitative Methodology ◽  
Analysis Method ◽  
Leadership Models ◽  
Content Analysis Method ◽  
Depth Analysis ◽  
Research Leadership ◽  
The Impact ◽  
Over Time

The aim of this study is to show the extent to which different models of leadership in education are studied, including changes in the trends of research on each model over time, the most prominent scholars working on each model, and the countries in which the articles are based. The analysis of related literature was first conducted using a bibliometric analysis of research and review papers indexed in the Science Database Web between 1980 and 2014. A more in-depth analysis of the selected papers was then carried out using the content analysis method. Results have shown that there has been an increasing interest in educational research leadership models over time. Distributed leadership, educational leadership, teacher leadership and transformational leadership are the most studied leadership models in education research. It was also found that related research increasingly focuses on the impact of leaders on organizational behaviors/conditions and student achievement. As a result, the use of quantitative methodology has increased significantly over the last decade. Possible reasons for such changes, implications and recommendations for future research are also discussed.

scholarly journals Potential predictors of adoption of the Tobacco Heating System by U.S. adult smokers: An actual use study

F1000Research ◽  
2021 ◽  
Vol 8 ◽  
pp. 214
Author(s):  
Steve Roulet ◽  
Christelle Chrea ◽  
Claudia Kanitscheider ◽  
Gerd Kallischnigg ◽  
Pierpaolo Magnani ◽  
...  
Keyword(s):  
Population Level ◽  
Heating System ◽  
Tobacco Consumption ◽  
Tobacco Product ◽  
Ease Of Use ◽  
Stepwise Logistic Regression ◽  
Stepwise Logistic Regression Analysis ◽  
Actual Use ◽  
Post Marketing ◽  
The Impact

Background: This was a pre-market, observational, actual use study with the Tobacco Heating System (THS), a candidate modified risk tobacco product. The main goal of the study was to describe THS adoption within current adult daily smokers by replicating the usage of THS in real-world conditions with participants being able to consume cigarettes, THS, and any other nicotine-containing products (e.g., e-cigarettes, cigars, etc.) ad libitum. Methods: This study assessed self-reported stick-by-stick consumption of THS compared with the use of commercial cigarettes over six weeks. The aim of the analysis was to identify potential predictors for adoption of THS using stepwise logistic regression analysis. Results: By the end of the observational period (in Week 6), 14.6% of participants (n=965) had adopted THS meaning that THS formed 70% or more of their total tobacco consumption. The main predictors of adoption were the liking of the smell, taste, aftertaste, and ease of use of THS. The proportion of adoption was higher in participants aged 44 years and older and in Hispanic or Latino adult smokers. Additionally, adoption of THS was more likely in participants who had never attempted to quit smoking and in participants who smoked up to 10 cigarettes per day. Finally, the adoption of THS was higher in participants who consumed both regular and menthol THS compared with those who consumed only one THS variant. Conclusions: The findings suggest that the introduction of THS in the U.S. has the potential to result in adoption by current adult smokers who would otherwise continue to smoke cigarettes, and that the adoption of THS is unlikely to result in an increase of tobacco consumption. Post-marketing studies will provide further insights on THS adoption and THS use patterns to allow assessment of the impact of the THS at the individual and the overall population level.

Understanding epidermal growth factor receptor mutation (EGFRm) testing in patients (pts) with non-small cell lung cancer (NSCLC) in a large community oncology network.

2018 ◽  
Vol 36 (30_suppl) ◽  
pp. 9-9
Author(s):  
Eric Nadler ◽  
Ancilla Fernandes ◽  
Melissa Pavilack ◽  
Susan Amirian ◽  
Jamyia Clark ◽  
...  
Keyword(s):  
Growth Factor Receptor ◽  
Stage Iv ◽  
Stepwise Logistic Regression ◽  
Stepwise Logistic Regression Analysis ◽  
Nccn Guidelines ◽  
Practice Size ◽  
Site Characteristics ◽  
Community Oncology ◽  
Epidermal Growth ◽  
Over Time

9 Background: EGFR TKI therapy improves outcomes in pts with EGFRm+ NSCLC. NCCN guidelines recommend EGFRm testing for pts with NSCLC. Testing patterns and predictors of documented EGFRm testing were studied in a real-world setting. Methods: Adult pts with stage IV NSCLC treated from 1/1/2012 to 8/31/2017, identified from the iKnowMed (US Oncology Network) EHR were analyzed. Rates of documented EGFRm testing were calculated. Multivariable stepwise logistic regression analysis was conducted to identify characteristics associated with documented EGFRm testing. Results: Of 14,461 pts, 59.8% had adenocarcinoma and 17.5% had squamous cell carcinoma. Median age of pts was 69.3 years, 52.3% were male, and 14.6% were non-smokers. Testing rates were ~36% overall, an increase in rates was seen over time: ~30% in 2012 to 41% in 2016 (p < .001). Histology, practice size, and several characteristics were associated with documented EGFRm testing (Table). Conclusions: Testing rates steadily increased over time, but were still low, implying suboptimal/under-documented testing. This analysis presents practice site characteristics to target educational programs to improve testing and/or documentation in community settings. [Table: see text]

The Therapist’s Reaction to a Patient’s Suicide

Crisis ◽  
2011 ◽  
Vol 32 (2) ◽  
pp. 99-105 ◽  
Author(s):  
Friedrich Martin Wurst ◽  
Isabella Kunz ◽  
Gregory Skipper ◽  
Manfred Wolfersdorf ◽  
Karl H. Beine ◽  
...  
Keyword(s):  
Emotional Responses ◽  
Well Being ◽  
Emotional Reaction ◽  
Emotional Reactions ◽  
Analog Scale ◽  
General Hospitals ◽  
Item Questionnaire ◽  
Retrospective Nature ◽  
The Impact ◽  
Over Time

Background: A substantial proportion of therapists experience the loss of a patient to suicide at some point during their professional life. Aims: To assess (1) the impact of a patient’s suicide on therapists distress and well-being over time, (2) which factors contribute to the reaction, and (3) which subgroup might need special interventions in the aftermath of suicide. Methods: A 63-item questionnaire was sent to all 185 Psychiatric Clinics at General Hospitals in Germany. The emotional reaction of therapists to patient’s suicide was measured immediately, after 2 weeks, and after 6 months. Results: Three out of ten therapists suffer from severe distress after a patients’ suicide. The item “overall distress” immediately after the suicide predicts emotional reactions and changes in behavior. The emotional responses immediately after the suicide explained 43.5% of the variance of total distress in a regression analysis. Limitations: The retrospective nature of the study is its primary limitation. Conclusions: Our data suggest that identifying the severely distressed subgroup could be done using a visual analog scale for overall distress. As a consequence, more specific and intensified help could be provided to these professionals.

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