scholarly journals Clinical case of associative course of panleukopenia and intestinal yersiniosis in cats

2021 ◽  
Vol 23 (103) ◽  
pp. 88-95
Author(s):  
O. O. Truba ◽  
G. A. A. Zon
Keyword(s):  
Clinical Case ◽  
Abiotic Factors ◽  
Clinical Signs ◽  
Rapid Test ◽  
Complete Recovery ◽  
Biological Properties ◽  
Modern Problem ◽  
Antibacterial Drugs ◽  
Antimicrobial Sensitivity ◽  
The Status

The study of the course and manifestation of mixed infections is an important modern problem of both humane and veterinary medicine because their diagnosis is quite complex and time-consuming. The clinical manifestation of double and sometimes triple infection has its characteristics, which depend on various biotic and abiotic factors. To date, it has been proven that the associative course of several infectious diseases is registered more and more often, which confirms the case of simultaneous manifestation of panleukopenia and intestinal yersiniosis in domestic outbred cats. Diagnosis of mixed infection was comprehensive through general clinical and laboratory studies, the use of rapid test systems to confirm the diagnosis of panleukopenia and RNGA with specific yersinia antigens to determine the status of intestinal yersiniosis in cats. The latter was caused by serovar Y. enterocolitica O: 9 with a diagnostic titer of 1: 400. Thanks to microbiological studies, the causative agent of intestinal yersiniosis Y. enterocolitica was isolated. Its biological properties were determined, and antimicrobial sensitivity to enrofloxacin and doxycycline was established against the background of polyresistance to ceftriaxone and tetracycline. During treatment, it was found that the clinical case of intestinal yersiniosis was also due to the simultaneous infection of Y. enterocolitica with two types of serotypes O: 3 and O: 9. Which also have their own specific features. But in most cases, we have different sensitivity to antibacterial drugs, in contrast to the case we described. Clinical signs of the associated course of panleukopenia and intestinal yersiniosis in domestic outbred cats were characterized by prolonged diarrhea, streaks of blood and mucus, apathy, refusal to feed, general weakness. Therapeutic measures containing antibacterial drugs, energy sources, crystalloids, buffer infusions which were aimed at reducing dehydration and maintaining water-salt balance in the complex, were effective, clinical signs of the disease disappeared on the eighth day of treatment, and complete isolation of the pathogen in the environment ceased on the thirteenth day, which indicated the complete recovery of the animal. However, to prevent re-infection, it was recommended to treat disinfectants with care items and utensils. And also to avoid direct contact with animals that have pronounced clinical signs of disease. To prevent the occurrence of panleukopenia, scheduled mass vaccinations with mandatory observance of time limits.

Thyroidectomy in a patient with a giant multinodular nontoxic cervical retrosternal goiter

2020 ◽  
pp. 97-99
Author(s):  
U. V. Kukhtenko ◽  
O. A. Kosivtsov ◽  
L. A. Ryaskov ◽  
E. I. Abramian
Keyword(s):  
Surgical Treatment ◽  
Clinical Case ◽  
Clinical Signs ◽  
Disease Relapse ◽  
Cardiac Pathology ◽  
Nontoxic Goiter ◽  
Retrosternal Goiter

A clinical case of successful surgical treatment of a patient with a giant cervical retrosternal nontoxic goiter with severe cardiac pathology is presented. Thyroidectomy from cervical access without sternotomy was performed. At the follow-up examination 5 months after the operation, instrumental and clinical signs of disease relapse were not detected.

Hypoglycemic Hemiparesis Masquerading As Ischemic Stroke: When Guideline Fails

2020 ◽  
Vol 15 (4) ◽  
pp. 420-422
Author(s):  
Dhruvkumar M. Patel ◽  
Mukundkumar V. Patel ◽  
Jayanti K. Gurumukhani ◽  
Maitri M. Patel ◽  
Himal J. Mahadevia ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Thrombolytic Therapy ◽  
Neurological Deficit ◽  
Clinical Case ◽  
Complete Recovery ◽  
Acute Onset ◽  
Diabetic Patients ◽  
Focal Neurological Deficit ◽  
Random Blood Sugar ◽  
Resident Doctor

Background: Hypoglycemia may rarely present as hemiparesis and sometimes it is difficult to differentiate from ischemic stroke. When random blood sugar (RBS) value is between 50 and 80 mg % in patients presenting with focal neurological deficit, no guideline exists to consider the possibility of hypoglycemia before initiating thrombolytic therapy. Clinical Case: A 58-year-old male, who was a known case of diabetes and hypertension, was brought to the emergency room with acute onset of right hemiparesis and dysarthria of 90 minutes duration. His NIHSS Score was 9, blood pressure was 150/90 mm of Hg and RBS was 79 mg% on admission. His CT scan brain was normal and was considered for thrombolysis. Resident doctor not aware of previous sugar repeated RBS before thrombolysis which was surprisingly 60 mg% 60 minutes after the first RBS. Even though he was a candidate for thrombolysis, intravenous 25 % dextrose was administered considering the possibility of hypoglycemia. He made a complete recovery within 20 minutes and thrombolytic therapy was withheld. : In Diabetic patients with focal neurological deficit and RBS less than 80 mg% on admission, RBS should be rechecked and in appropriate cases should be challenged with IV dextrose considering the possibility of hypoglycemia before commencing thrombolytic therapy.

scholarly journals Deletion of the L7L-L11L Genes Attenuates ASFV and Induces Protection against Homologous Challenge

Viruses ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 255
Author(s):  
Jingyuan Zhang ◽  
Yanyan Zhang ◽  
Teng Chen ◽  
Jinjin Yang ◽  
Huixian Yue ◽  
...  
Keyword(s):  
African Swine Fever Virus ◽  
Clinical Signs ◽  
African Swine Fever ◽  
Biological Properties ◽  
High Dose ◽  
Swine Industry ◽  
Epidemic Disease ◽  
Intramuscular Inoculation ◽  
Homologous Challenge

African swine fever (ASF), caused by the African swine fever virus (ASFV), is a major epidemic disease endangering the swine industry. Although a number of vaccine candidates have been reported, none are commercially available yet. To explore the effect of unknown genes on the biological characteristics of ASFV and the possibility of a gene-deleted isolate as a vaccine candidate, the strain SY18ΔL7-11, with deletions of L7L–L11L genes from ASFV SY18, was constructed, and its biological properties were analyzed. The results show that deletion of genes L7L-L11L did not affect replication of the virus in vitro. Virulence of SY18△L7-11 was significantly reduced, as 11 of the 12 pigs survived for 28 days after intramuscular inoculation with a low dose (103 TCID50) or a high dose (106 TCID50) of SY18ΔL7-11. All 11 surviving pigs were completely protected against challenge with the parental ASFV SY18 on 28 days postinoculation (dpi). Transient fever and/or irregularly low levels of genomic DNA in the blood were monitored in some pigs after inoculation. No ASF clinical signs or viremia were monitored after challenge. Antibodies to ASFV were induced in all pigs from 14 to 21 days postinoculation. IFN-γ was detected in most of the inoculated pigs, which is usually inhibited in ASFV-infected pigs. Overall, the results demonstrate that SY18ΔL7-11 is a candidate for further constructing safer vaccine(s), with better joint deletions of other gene(s) related to virulence.

scholarly journals Changes in the oral cavity caused by scurvy

2003 ◽  
Vol 60 (6) ◽  
pp. 753-756 ◽  
Author(s):  
Dragana Dakovic ◽  
Besir Ljuskovic ◽  
Ivan Mileusnic ◽  
Vesna Tepsic
Keyword(s):  
Vitamin C ◽  
Oral Cavity ◽  
Rare Disease ◽  
Clinical Examination ◽  
Psychiatric Patient ◽  
Clinical Signs ◽  
Complete Recovery ◽  
Vitamin C Deficiency ◽  
Plaque Control ◽  
Prompt Diagnosis

This report presents a case of a psychiatric patient with scurvy. Upon the clinical examination of the oral cavity, dry and pale lips were noted. Gingiva was highly edematous, soft, purple blue with ulcerated margins. Bleeding was noted upon slightest provocation. Teeth were also affected by the vitamin C deficiency with multiple caries. The patient was asthenic and adynamic. Petechial bleeding and hematomas were present on the skin of extremities. Therapy consisted of rehydration and vitamin C compensation - 2 g daily i.v. during 10 days period, and 1.5 g daily orally during the following 2 months. The patient maintained only partial plaque control, and complete recovery of the oral cavity was not established because the patient didn?t comply. Concerning that scurvy is a rare disease nowadays, it is very important to recognize its clinical signs, and to establish a valid and prompt diagnosis, because, when untreated, scurvy can have severe consequences on the entire organism.

scholarly journals Clinico-epidemiological features of Japanese encephalitis patients hospitalized in a tertiary care center

2018 ◽  
Vol 5 (10) ◽  
pp. 4548
Author(s):  
Abu Hasan Sarkar ◽  
Bishnu Ram Das
Keyword(s):  
Japanese Encephalitis ◽  
Care Center ◽  
Tertiary Care ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Complete Recovery ◽  
High Morbidity ◽  
Medical College ◽  
Clinical Signs And Symptoms ◽  
One Year

Background: Japanese encephalitis (JE) is of particular interest as it has a high morbidity and mortality. Neurological sequale is the most dreaded damage caused by JE. It is a preventable disease with specific interventions. The objective of the study was to study the demography, clinical profile and outcome of patients with Japanese Encephalitis admitted to the wards of Internal Medicine and Pediatrics at Jorhat Medical College Hospital.Methods: Hospital based observational study for one year in Jorhat Medical College, Jorhat, Assam.Results: The mean age for JE was 32.25±27 years for male, 27.47±22 years for female and 29.94±24 years overall. Assessment of clinical signs and symptoms showed that fever and change in mental status were present in 100% of JE cases followed by neck rigidity in 79.3% and headache in 68.9%. 44.8% of JE cases had history of seizure, 37.9% had vomiting, 34.5% had irritability, 13.8% were unconscious. The peak of JE incidence occurred in the month of July (77.6%). Complete recovery was seen in 39.2%, followed by death in 32.6% and recovery with neurological sequalae in 28.2% at the time of discharge.Conclusions: Vigorous awareness activities should be carried out to sensitize people on prevention of JE. 

scholarly journals Paediatric Hypophosphatasia in Real-Life Clinical Practise.

Doctor Ru ◽  
2020 ◽  
Vol 19 (10) ◽  
pp. 57-60
Author(s):  
A.V. Vitebskaya ◽  
◽  
Chernova E.V. Chernova ◽  
Keyword(s):  
Alkaline Phosphatase ◽  
Clinical Case ◽  
Clinical Signs ◽  
Real Life ◽  
Compound Heterozygous Mutation ◽  
Heterozygous Mutation ◽  
Compound Heterozygous ◽  
Milk Teeth ◽  
Motor Retardation ◽  
Gait Disturbances

Objective of the Paper: to describe a clinical case of paediatric hypophosphatasia (HPP) and identify clinical signs, most characteristic of the paediatric HPP form. Key Points. HPP is an congenital rickets-like disease caused by reduced activity of tissue-nonspecific alkaline phosphatase (ALP). According to the time of manifestation, there are perinatal, infant, paediatric, and adult HPPs. The article describes a clinical case of paediatric HPP in a 3.5-year old boy. HPP was diagnosed due to reduced ALP and characteristic X-ray findings. The diagnosis was confirmed with DNA testing: compound heterozygous mutation in с.571 G>A/с.144_148dup of ALPL was found. Conclusion. Typical findings in paediatric HPP are growth retardation and muscular hypotonia, motor retardation; gait disturbances, myalgia, marked fatigue causing limited period of walking; rachitic deformations, premature loss of milk teeth with unchanged roots, respiratory disturbances, and frequent bronchopulmonary disorders. Keywords: hypophosphatasia, children, alkaline phosphatase.

scholarly journals CYSTOSTOMY DUE TO URETHRAL OBSTRUCTION IN A CAT: CLINICAL CASE

2021 ◽  
Vol 245 (1) ◽  
pp. 215-218
Author(s):  
N.V. Shamsutdinova ◽  
◽  
Keyword(s):  
Veterinary Medicine ◽  
Clinical Case ◽  
Complete Recovery ◽  
Treatment Method ◽  
Anatomical Structure ◽  
Urethral Obstruction ◽  
Common Reason ◽  
Adequate Treatment ◽  
Urgent Task

Violation of the process of urination in cats is a fairly common reason for owners to contact veterinary clinics. The development of an adequate treatment method for urethral obstruction, based on the pathogenesis of the disease and taking into account the anatomical structure of the cat's urinary sys-tem, remains an urgent task of modern veterinary medicine. Cystotomy with suturing of the catheter and subsequent detoxification therapy can achieve complete recovery, as the cause of blockage of the urethra is eliminated.

scholarly journals Biomarkers as predictive tools to test the in vivo anti-sarcoptic mange activity of propolis in naturally infested rabbits

2018 ◽  
Vol 38 (6) ◽  
Author(s):  
Dina M. Metwally ◽  
Ebtesam M. Al-Olayan ◽  
Reem A. Alshalhoop ◽  
Shatha A. Eisa
Keyword(s):  
Microscopic Examination ◽  
Clinical Signs ◽  
Serum Cortisol ◽  
Complete Recovery ◽  
Sarcoptic Mange ◽  
Serum Total Protein ◽  
Predictive Tools ◽  
Aspartate Amino Transferase ◽  
The Impact

The present study was designed to investigate the use of specific biomarkers, such as albumin, serum total protein, aspartate amino transferase (AST), globulin, alanine amino transferase (ALT), serum cortisol and alkaline phosphatase (ALP), as predictive tools for sarcoptic mange in rabbits. A total of 40 naturally infested rabbits were equally divided into four groups.Thirty infested rabbits were administered with three different treatments (propolis,ivermectin, and propolis with ivermectin) and were compared to10 infested un-treated rabbits. The impact of treatment was assessed via microscopic examination of skin scrapings, clinical signs, and blood measurements relating to the liver. The present study demonstrated that topical application of 10% propolis ointment resulted in complete recovery from clinical signs and complete absence of mites based on microscopic examination after 10–15 days of treatment. Moreover, AST, ALP, ALT, and cortisol were determined to be acceptable biomarkers to track the response of diseased rabbits to the therapeutic use of propolis.

Clinical case of diagnosis of primary open-angle glaucoma in a patient after previously performed anterior radial keratotomy

2021 ◽  
pp. 126-131
Author(s):  
R.A. Burya ◽  
◽  
A.A. Fil ◽  
E.L. Sorokin ◽  
◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Clinical Case ◽  
Primary Open Angle Glaucoma ◽  
Low Vision ◽  
Open Angle Glaucoma ◽  
Clinical Signs ◽  
Primary Diagnosis ◽  
Applanation Tonometry ◽  
Open Angle ◽  
Radial Keratotomy

The article describes a clinical case of diagnosis and detection of primary open-angle glaucoma (POAG) in a patient after previously performed anterior dosed radial keratotomy (ADRK). The reasons that hampered the primary diagnosis of POAG in the presented patient at an outpatient appointment with an ophthalmologist were: inadequate assessment of the ratio of the state of the lenses and low vision; a falsely underestimated level of tonometric intraocular pressure (IOP), as well as the absence of an in-depth ophthalmoscopic assessment of the condition of the optic nerve head, failure to comply with the mandatory perimetric examination in such cases. It should be especially remembered that there is a high likelihood of underestimation of applanation tonometry indices after performing ADRK, therefore, the assessment of its results should be treated with caution, identifying other clinical signs characteristic of glaucoma. This will make it possible to diagnose glaucoma in time and prescribe pathogenetic treatment in a timely manner. Key words: anterior dosed radial keratotomy, primary open-angle glaucoma, intraocular pressure.

scholarly journals Study on prevalence of bovine diseases at sadar upazila in dinajpur district of Bangladesh

2018 ◽  
Vol 3 (4) ◽  
pp. 446-453 ◽  
Author(s):  
Moktar Omar Mohammed ◽  
Md Shajedur Rahman ◽  
Md Fazlul Hoque ◽  
Nazmi Ara Rumi ◽  
Osman Hassan Afrah
Keyword(s):  
Venereal Disease ◽  
Winter Season ◽  
Clinical Signs ◽  
Disease Diagnosis ◽  
Summer Season ◽  
Viral Diseases ◽  
Parasitic Diseases ◽  
Bacterial Diseases ◽  
Cattle Diseases ◽  
The Status

The study was conducted to investigate the status of cattle diseases with relation to seasonal variation in Dinajpur district of Bangladesh. A total of 11402 clinical cases were registered for the clinical diagnosis and therapeutic purposes at sadar upazila veterinary hospital in Dinajpur district of Bangladesh during the period of March, 2016 to February, 2017. Disease diagnosis was made on the basis of owner’s statement, general examination and clinical signs. Diagnosed diseases were categorized as general clinical disorders, parasitic diseases, viral diseases, bacterial diseases, venereal disease, and metabolic disorders. According to study the highest (64.15%) prevalence was by parasitic disease followed by bacterial diseases (10.67%), viral diseases (8.97%), metabolic disease (7.61%), and venereal disease (6.60%). In respect of seasons, the prevalence of both bacterial diseases and viral diseases were significantly (p<0.01) higher (13.88%) and (12.10%) in summer season respectively. Whereas the parasitic diseases were significantly (p<0.01) higher (68.65%) in winter season. On the basis of season, it was found that the overall prevalence of diseases was highest in summer season (47.87%) followed by rainy season (30.10%) and comparatively lower in winter season (22.03%).Asian J. Med. Biol. Res. December 2017, 3(4): 446-453

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