scholarly journals The features of the course and some diagnostic aspects of pancreatitis in cats

2018 ◽  
Vol 20 (88) ◽  
pp. 94-97
Author(s):  
O. M. Kovalchuk ◽  
I. Y. Horalska
Keyword(s):  
Alkaline Phosphatase ◽  
Red Blood Cells ◽  
Total Protein ◽  
Blood Cells ◽  
Total Bilirubin ◽  
The Body ◽  
Endocrine Function ◽  
Glucose Content ◽  
Blood Tests ◽  
Diagnostic Aspects

The results of clinical examination of patients of animals, collected history and conducted laboratory blood tests with determination of the number of red blood cells, leukocytes, platelets, hemoglobin, glucose, total protein, total bilirubin, activity of ALT, AST, alkaline phosphatase and α-amylase enzymes are presented in the article. The features of the course and some diagnostic aspects of pancreatitis in cats are described. According to the results of the studies and their detailed analysis, it has been established that the clinical manifestation of pancreatitis in cats has certain differences from the manifestation of this disease in other carnivores, namely dogs, and is characterized by nonspecific clinical features - inhibition, anorexia, cachexia, occasionally – vomiting. Dehydration, pallor of visible mucous membranes of the conjunctiva and skin, or, in severe cases, their jaundice, abdominal pain, fever, or hypothermia are typical for sick animals. Thus, according to the results of own research and the collected information on the clinical condition of cats, the manifestation of the disease in the form of oppression and cachexia was observed in 100% of patients, vomiting – in 10%, anorexia – in 80% of patients. In 33% of diseased animals, a fever of constant type was diagnosed to 41.6 °C, in the rest of the animals the temperature of the body was normal or at its lower limit. Laboratory tests of anemia showed anemia with a decrease in the number of red blood cells and hemoglobin to 4.6 ± 0.57 T/L and 91.7 ± 5.62 g/l, respectively. Anemia was not regenerative, confirmation of why there was no blood in sick animals of reticulocytes. As a manifestation of the compensatory possibilities of the body of sick cats for the development of pancreatitis can be considered not significantly expressed thrombocytopenia. Thus, the number of blood platelets in experimental animals was in the range of 136.8 ± 32.2 G/L, at a rate of 250–600 G/L. This can be explained by the fact that platelets are also involved in protecting the body from microorganisms and toxins, and this pathological process is accompanied by their reduction. Hyperproteinemia, hypoalbuminemia, hyperbilirubinemia, hyperglycemia, hyperbilirubinemia, and hyperfermentemia of transaminases and α-amylase were determined by biochemical blood tests in cats for pancreatitis. Therefore, in 67% of patients in cats hyperglycemia with elevated values of glucose content up to 8.9 ± 0.85 g/l was detected, indicating a violation of the endocrine function of the pancreas. In 100% of the sick animals, an increase in the total protein content was observed on average up to 86.2 ± 3.7 g/l, which can be considered as a consequence of the dehydration of the patient's body and an increase in the proportion of blood globulin. Most number of oll cats has a violation of the function of the liver. Thus, the damage to the integrity of membranes and hepatocyte cytolysis was indicative of an increase in the activity of blood serum enzymes – ALT (up to 186.3 ± 23.1 OD/L) and AST (up to 159.2 ± 31.6 OD/l). In violation of the delay in the removal of bile, the permeability of membranes of the epithelium of the biliary tract indicated an increase in the activity of alkaline phosphatase to 230.2 ± 10.5 ODP/l in 67% of cases. For other cases, it was characterized by a decrease in its activity to 9.3 ± 0.3 Od/liter, which can be explained by the development of an imbalance in the nutritional intestinal microflora, that is, the presence in the sick of cats of dysbiosis, also caused by a violation of the metabolism of vitamin C in their body. Swelling resulting from inflammation of the pancreas and tissues surrounding it has probably led to mechanical obstruction of the total bile duct, which was confirmed by an increase in the total bilirubin level to 14.2 ± 2.4 μmol/l.

scholarly journals BIOLOGICAL EFFECTS OF SILICON OXIDE NANOPARTICLES ON BROILER CHICKEN

2020 ◽  
Vol 5 (2) ◽  
pp. 63-71
Author(s):  
Vladimir Nikulin ◽  
Aleksandra Mustafina
Keyword(s):  
Red Blood Cells ◽  
Total Protein ◽  
Blood Cells ◽  
Broiler Chickens ◽  
Broiler Chicken ◽  
Silicon Oxide ◽  
The Body ◽  
Control Group ◽  
The Third ◽  
Experimental Group

The aim of the study is to increase the productive qualities of broiler chickens by including ultrafine silicon oxide into main diet. During the experiment, the biological effect of ultrafine silicon oxide on broiler chickens was estab-lished. Use of ultrafine SiO2 particles for poultry feeding contributed to an increase in the number of red blood cells and content of total protein and albumins. By the end of the experiment, the number of red blood cells in birds in-creased by 17.43% (P≤0.001) – in the blood of birds of the first experimental group, 16.51% (P≤0.01) – the second one, 20.80% (P≤0.001) – the third experimental and 21.71% (P≤0.001) – the fourth experimental group, compared with the indicator of the control group. The amount of total protein in blood serum of chickens of the first and the second experimental groups increased by 1.36-1.39 %, in the third and fourth ones there was a significant (P≤0.05) increase by 5.45 and 3.05%, respectively. The blood glucose content of chickens in the experimental groups is higher by 8.04-23.65% compared to this indicator with ones in the control group. During the experiment feed con-sumption per 1 kg gain of live weight decreased: in the first experimental group by 3.00 % in the second by – 0.50 %, the third – 6.00 % the fourth– by 4.50 %, compared to this with the control group. The chicken’s vibrancy of the first the experimental group was higher by 4.77 %, the second – by 6.20 %, the third – by 19.25 % and the fourth– by 11.59% than in the control one. Consequently, when converting the feed energy into the body energy of a broiler chicken, the energy conversion coefficient of the experimental group of poultry is higher than that of the control one by 7.16-21.76 %. Thus, the most optimal dose for further research was determined.

scholarly journals DOSE-DIFFERENTIATED CORRELATION INTERACTIONS BETWEEN INDICES OF HEMOGLOBIN EXCHANGE IN TURKEYS UNDER THE INFLUENCE OF THE PROBIOTIC FORMULATION VETOM 1.2

2020 ◽  
pp. 82-91 ◽  
Author(s):  
M. S. Yakovleva ◽  
N. S. Yakovleva ◽  
N. A. Gotovchikov ◽  
S. N. Tishkov ◽  
L. P. Ermakova
Keyword(s):  
Serum Albumin ◽  
Red Blood Cells ◽  
Total Protein ◽  
Blood Cells ◽  
Bacillus Amyloliquefaciens ◽  
Total Bilirubin ◽  
Inverse Correlation ◽  
Direct Bilirubin ◽  
Subsequent Decrease ◽  
Probiotic Preparation

The effect of the probiotic preparation Vetom 1.2 on the basis of Bacillus subtilis VKPM B-10641, Bacillus amyloliquefaciens VKPM B-10642 and Bacillus amyloliquefaciens VKPM B-10643 in different doses on the correlation interactions between the parameters of turkey hemoglobin exchange, blood erythrocytes and blood red blood cells direct and total bilirubin, total protein and serum albumin was studies. Correlations were calculated using Spearman formula, the reliability of correlations was checked by Student. The formulation was used for turkeys once a day for 30 days in doses of 12.5; 25; fifty; 75 and 100 mg / kg body weight. It was found that Vetom 1.2 in minimal doses leads to an inverse correlation between iron and total bilirubin, direct bilirubin, total protein and albumin, an increase in the concentration of the formulation leads to the disappearance of this effect with a gradual subsequent decrease in this indicator. Vetom 1.2 in doses up to 50 mg / kg leads to an inverse correlation between the concentrations of hemoglobin and direct bilirubin, total protein and serum albumin, at a dose of 75 mg / kg there is a direct correlation between these indicators, and at a dose of 100 mg / kg returns a negative correlation. The probiotic preparation Vetom 1.2 leads to a direct dependence of the concentration of bilirubins (total and direct) in serum on the concentrations of hemoglobin and red blood cells when used in most doses, except 75 mg / kg, which reduces the correlation.

scholarly journals THE INFLUENCE OF NEW BEDDING MATERIAL ON MORPHOBIOCHEMICAL AND IMMUNOLOGICAL PARAMETERS OF BLOOD OF GOSLINGS OF BROILERS

2021 ◽  
Vol 247 (3) ◽  
pp. 244-248
Author(s):  
V.G. Sofronov ◽  
◽  
R.N. Fayzrakhmanov ◽  
N.I. Danilova ◽  
E.L. Kuznetsova ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Total Protein ◽  
Blood Cells ◽  
Inorganic Phosphorus ◽  
The Body ◽  
Allergic Reactions ◽  
Bedding Material ◽  
Total Calcium ◽  
Immunological Parameters ◽  
Mucous Membranes

The harmlessness of the new hygienic bedding material and the effect of broilers on the body have been studied. During the experiment, it was found that the new hygienic litter material, representing waste from the woodworking industry, treated with thermochemical and biotechnological methods, does not have an irritating effect on the skin, does not irritate the mucous membranes of the eyes and allergic reactions in rabbits, but, on the contrary, improves certain morphobiochemical and immunological parameters of the body’s blood are goslings. Ultimately, this was reflected in an increase in red blood cells by 7.04 %, hemoglobin – 5.20 %, total protein – 6.3 %, total calcium – 5.8 %, inorganic phosphorus – 5.1 %, glucose – 5,4 % compared with the control.

scholarly journals Гематологічні і біохімічні показники крові собак за умов застосування «Неоверму» та протекторів-антитоксикантів

2017 ◽  
Vol 19 (73) ◽  
pp. 46-49
Author(s):  
I.O. Zhukova ◽  
I.O. Kostyuk ◽  
Yu.S. Svitlychna-Kulak
Keyword(s):  
Alkaline Phosphatase ◽  
Red Blood Cells ◽  
Toxic Effect ◽  
Functional State ◽  
Blood Cells ◽  
Negative Impact ◽  
Hematological Parameters ◽  
The Body ◽  
Feed Additive ◽  
Control Group

The article presents the data on the effect of antihelmintic and imunomodulating drug «Neoverm» on the dogs’ body when the drug was administered into the stomach of the animals within three days and the results of its application in the combination with the drugs that contain antioxidant and membrane stabilizing substances. To protect the body from toxic action of «Neoverm» the drugs were used under two schemes: «E-Selenium» and «Quercetin», phospholipid hepaprotector «Lesphal» and «green buckwheat» (a feed additive – pre-ground raw buckwheat as a natural source of quercetin). The result a were compared with the control group and the group that received only «Neoverm». It has been found out that the use of «Neoverm» for the dogs both on the 7th and 14th days had a negative impact on the hematological parameters and the activity of blood enzymes that reflects the functional state of the liver. In particular, the reduction in the number of erythrocytes and the level of hemoglobin as well as the significant increase in the activity of diagnostic enzymes: alanine (ALT), asparagine (AST), gammaglutamyl (GGT) transferases and alkaline phosphatase (ALP) have been revealed. The proposed schemes to correct the toxic effect of the drug «Neoverm» in dogs led to the restoration of endogenous antitoxic resources, that is, to a gradual normalization of hematological parameters and the activity of indicatory enzymes of blood (the decrease in the activity of AST, ALT, GGT, ALP and LDH and the normalization of the number of red blood cells and hemoglobin) and that is the basis for the use of the above drugs as protectors-antioxidants when «Neoverm» is used.

Pickled olives neutralize vicine and convicine glycosides in Vicia faba and protect from favism

2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Khaled M. M. Koriem ◽  
Mahmoud S.S. Arbid
Keyword(s):  
Alkaline Phosphatase ◽  
Liver Function ◽  
Oral Administration ◽  
Total Protein ◽  
Blood Cells ◽  
Total Bilirubin ◽  
Serum Glucose ◽  
Liver Protein ◽  
Content Type ◽  
Serum Aspartate Aminotransferase

Purpose This paper aims to evaluate hematological parameters, blood glutathione (GSH), serum glucose-6-phosphate dehydrogenase (G6-PD) and liver function in favism animals' models after oral intake with a mixture of pickled olives and Vicia faba (V. faba) seeds. Design/methodology/approach Favism is a life-threatening hemolytic crisis. It results from the ingestion of V. faba by the individuals. The hemoglobin (Hb), hematocrit (Hct), red blood cells (RBCs), white blood cells (WBCs), serum glucose, blood GSH, serum G6-PD, serum thiobarbaturic acid reactive substances (TBARS), liver protein and liver function were evaluated after oral administration with a mixture of pickled olives with V. faba seeds in favism animals' models. Findings The favism-, vicine- and convicine-treated animals showed a significant decrease (p < 0.01) in Hb (6.42, 7.23 and 5.96 g/dl), Hct (25.4, 26.4 and 25.1%), RBCs (2.56, 2.45 and 2.60 106 cells/mm3, WBCs (4.35, 4.25 and 4.30 103 cells/mm3), serum glucose (95.8, 97.1 and 96.5 mg/dl), blood GSH (24.7, 26.6 and 23.8 mg/dl), serum G6-PD (15.8, 15.9 and 15.7 U/L), serum aspartate aminotransferase (6.35, 6.59 and 5.97 U/L), alanine aminotransferase (4.49, 4.61 and 4.50 U/L), total protein (6.54, 6.59 and 6.40 g/dl), albumin (3.84, 3.91 and 3.75 g/dl), globulin (2.70, 2.48 and 2.65 g/dl) and liver protein (3.37, 3.10 and 3.42 g/g tissue) but a significant increase (p < 0.01) in serum TBARS (38.7, 38.9 and 39.4 nmol/dl), alkaline phosphatase (275, 271 and 281 U/L) and total bilirubin (0.93, 0.89 and 0.91 mg/dl) compared to Hb (16.3 g/dl), Hct (45.3%), RBCs (5.80 106 cells/mm3), WBCs (9.45 103 cells/mm3), serum glucose (96.5 mg/dl), blood GSH (39.7 mg/dl), serum G6-PD (36.1 U/L), serum TBARS (18.0 nmol/dl), serum aspartate aminotransferase (19.8 U/L), alanine aminotransferase (9.23 U/L), alkaline phosphatase (214 U/L), total bilirubin (0.57 mg/dl), total protein (8.76 g/dl), albumin (4.85 g/dl), globulin (3.91 g/dl) and liver protein (6.28 g/g tissue) in control group. The oral administration with pickled olives + V. faba, pickled olives + vicine and pickled olives + convicine into favism animals' models, vicine-treated animals and convicine-treated animals, respectively pushed all the above-mentioned parameters to near the control levels. Originality/value V. faba contains vicine and convicine glycosides. Vicine and convicine glycosides in V. faba are hydrolyzed by intestinal microflora to aglycones divicine and isouramil, respectively. Divicine and isouramil are highly reactive compounds generating free radicals where divicine and isouramil are the main factors of favism. The ß-glucosidase in pickled olives converts both vicine and convicine glycosides into aglycones divicine and isouramil, respectively, in aerobic condition outside the human body (in inactive forms) and prevent these glycosides to cause favism.

scholarly journals НЕСПЕЦІФІЧНА РЕЗИСТЕНТНІСТЬ КОЗЕНЯТ ЗА ДІЇ ПРОБІОТИКА «ЕВІТАЛІЯ» В УМОВАХ НЕ РЕГУЛЬОВАНОГО МІКРОКЛІМАТУ

2016 ◽  
Vol 18 (3(70)) ◽  
pp. 196-200
Author(s):  
A.N. Petrenko ◽  
L.L. Kushch
Keyword(s):  
Relative Humidity ◽  
Red Blood Cells ◽  
Total Protein ◽  
Blood Cells ◽  
White Blood Cells ◽  
The Body ◽  
Natural Resistance ◽  
Total Protein Content ◽  
Humoral Factors ◽  
Freeze Dried

Probiotic «Evitaliya» is freeze–dried, specific strains of lactic acid microorganisms (Lactococcus lactis, Streptococcus thermophilus, Lactobacillus acidophilus, Lactobacillus helveticus, Propionibacterium fredenreichii ssp shernanii), they contain vitamins B1, B2, B6, B12, A, E, C iron minerals, calcium, magnesium.The purpose of the study was to clarify the effect of the probiotic ferment «Evitaliya» on nonspecific resistance of kids zaanovskoy breed microclimate conditions according VNTP (for sheep and goat breeding enterprises): the room temperature 12–14 °C, relative humidity of 55 – 70%, the carbon dioxide content – 1.5 – 1.8 l/m3 and ammonia – 10 – 15mg/m3 air bacterial contamination 15 – 20 tys. KOE/m3. Implementation of this goal was decided to use hygienic (temperature, relative humidity, air velocity); hematological (red blood cells, white blood cells, hemoglobin), biochemical (total protein, albumin, globulin); immune (humoral factors – lysozyme and bactericidal activity of blood serum, cell – the neutrophil phagocytic activity), statisticsGetting results and their novelty: for the first time tested the new probiotic yeast «Evitaliya», with its goats orally at a dose of – 200 ml/head in the morning and evening, 100 ml.It was found that the use of «Evitaliya» promotes activation of redox processes in the body kids, stimulation of erythropoiesis: increase in hemoglobin concentration of 0.56% (P ≤ 0.05), the number of red blood cells to – 10.2% (P ≤ 0.05).Use of the drug is moderately activates metabolic processes in the body of kids: increases total protein content by 7.14% (P ≤ 0.05), globulin – by 1.76% (P ≤ 0.05). Use of the drug «Evitaliya» at the indicated doses helps stimulate natural resistance olrganіzmu kids: humoral protection indicators (BASK) rose by 1.52% (LASK) by 1.81%, the cell indices (FA) compared to the control were higher – 4.97%. 

scholarly journals The effectiveness of the use of a biologically active additive ekobentokorm in the diets of cattle

2021 ◽  
Vol 273 ◽  
pp. 02007
Author(s):  
Galina Zelenkova ◽  
Sergei Tresnitskii ◽  
Pavel Bykadorov ◽  
Anna Pecinovsky ◽  
Aleksandr Yenin ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Total Protein ◽  
Blood Cells ◽  
Physiological State ◽  
The Body ◽  
Biologically Active ◽  
Protein Fractions ◽  
Natural Resistance ◽  
Neutrophil Granulocytes ◽  
High Biological Activity

Studies have established the effect of ekobentokorm (TU 9283-199-10514645-13-2013) on the metabolism of cows and the natural resistance of young black-and-white breed. The physiological state of cows was assessed by morphological and biochemical studies of blood, in which changes in the body’s metabolic processes were tracked in dynamics according to the following indicators: the number of red blood cells and hemoglobin level, total protein and protein fractions, glucose, urea, aminotransferases (AST, ALT), total calcium and inorganic phosphorus, trace elements (Mg, Zn, Fe, Cu) and carotene. The indicators characterizing the natural resistance of young animals were studied: red blood cells, white blood cells, hemoglobin, color index, total protein and protein fractions, phagocytic activity of neutrophil granulocytes, bactericidal and lysozyme activity of blood serum, the content and concentration of T-and B-lymphocytes, the level of circulating immune complexes (CIC). As a result of the conducted research, it was found that ekobentokorm has high biological activity, improves morphological and biochemical parameters of cows blood, and also increases milk productivity. It has a pronounced stimulating effect on the immunocompetent systems of the body of young animals, as a result of which the level of non-specific protection of the animal increases.

Clock gene-independent daily regulation of haemoglobin oxidation in red blood cells

2021 ◽  
Author(s):  
Andrew D. Beale ◽  
Priya Crosby ◽  
Utham K. Valekunja ◽  
Rachel S. Edgar ◽  
Johanna E. Chesham ◽  
...  
Keyword(s):  
Circadian Rhythms ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Human Subjects ◽  
Developmental Regulation ◽  
Physiological Role ◽  
Cell Types ◽  
The Body

AbstractCellular circadian rhythms confer daily temporal organisation upon behaviour and physiology that is fundamental to human health and disease. Rhythms are present in red blood cells (RBCs), the most abundant cell type in the body. Being naturally anucleate, RBC circadian rhythms share key elements of post-translational, but not transcriptional, regulation with other cell types. The physiological function and developmental regulation of RBC circadian rhythms is poorly understood, however, partly due to the small number of appropriate techniques available. Here, we extend the RBC circadian toolkit with a novel biochemical assay for haemoglobin oxidation status, termed “Bloody Blotting”. Our approach relies on a redox-sensitive covalent haem-haemoglobin linkage that forms during cell lysis. Formation of this linkage exhibits daily rhythms in vitro, which are unaffected by mutations that affect the timing of circadian rhythms in nucleated cells. In vivo, haemoglobin oxidation rhythms demonstrate daily variation in the oxygen-carrying and nitrite reductase capacity of the blood, and are seen in human subjects under controlled laboratory conditions as well as in freely-behaving humans. These results extend our molecular understanding of RBC circadian rhythms and suggest they serve an important physiological role in gas transport.

EFEKTIVITAS PEMBERIAN INFUSED WATER KURMA TERHADAP PENINGKATAN KADAR HEMOGLOBIN REMAJA PUTRI KEBIDANAN POLTEKKES MEDAN TAHUN 2020

2021 ◽  
Vol 2 (1) ◽  
pp. 64-69
Author(s):  
HIJRA HIDAYANA ◽  
Suswati Suswati
Keyword(s):  
Red Blood Cells ◽  
Adolescent Girls ◽  
Blood Cells ◽  
The Body ◽  
Rank Test ◽  
Plain Water ◽  
P Value ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Signed Rank Test

Hemoglobin is the red pigment-protein contained in red blood cells. The function of hemoglobin is to transport oxygen from the lungs and in the bloodstream to be carried to the tissues. Hemoglobin can increase by increasing the intake of iron in the body. One way to increase hemoglobin can be done by giving method Infused Water Dates. Infused water is a drink consisting of plain water with fresh fruit added and soaking or settling together for a certain time. The making of infused water is carried out by soaking for a period of 0 to 12 hours, so that the infused water becomes a liquid medium that carries more nutrients than ordinary water and will be more easily absorbed by cells and distributed throughout the body (Sidauruk, 2018 ). In several studies, it is stated that dates can increase hemoglobin levels in the blood. Where dates contain iron, vitamin A, vitamin C, protein to form red blood cells. With the method, Infused Water the date palm water becomes alkaline so that it can accelerate the absorption process in the body. The purpose of this study was to determine the effectiveness of dates infused water provision to increase hemoglobin levels of midwifery adolescent girls at Medan Health Polytechnic in 2020. This research was quasi-experimental study using the One Group Pretest-Posttest Without Control Design approach. The sample in this study were 20 respondents of midwifery adolescent girls from Medan Health Polytechnic, using the technique of purposive sampling. The statistical test used wa the Wilcoxon Signed Rank Test because the data was not normal. The results of the Wilcoxon Signed Rank Test obtained the value of P-Value = 0.001. So it can be concluded that the date infused water  is effective in increasing hemoglobin levels of midwifery adolescent girls at Medan Health Polytechnic in 2020.   Keywords: Dates Infused Water, Increased Hemoglobin Levels, Girls Adolescent

Sign in / Sign up

Export Citation Format

Share Document