scholarly journals EVALUATION OF RENAL FUNCTION BEFORE AND AFTER CHEMOTHERAPY IN NASOPHARYNGEAL CANCER IN LOMBOK

2019 ◽  
Vol 1 (1) ◽  
pp. 01-02
Author(s):  
Hamsu Kadriyan ◽  
Muhammad Alfian Sulaksana ◽  
Nurhidayati ◽  
Baiq Endang Suprihartini
Keyword(s):  
Renal Function ◽  
Serum Level ◽  
Blood Urea Nitrogen ◽  
Nasopharyngeal Cancer ◽  
The Other ◽  
P Value ◽  
Urea Nitrogen ◽  
Other Hand ◽  
Significant Difference ◽  
Before And After

Introduction Combination of chemotherapy and radiation are the treatment of choice in advance stage of nasopharyngeal cancer. Cisplatin-based chemotherapy is a regiment of choice in those cases. Several studies show that cisplatin-based chemotherapy affect renal function. Aims of the study to evaluate and compare the renal function before and after chemotherapy through comparing the blood urea nitrogen and creatinine serum level in patients with nasopharyngeal cancer who receive cisplatin and paclitaxel chemotherapy. Methods Design of this study is before and after using medical records data in West Nusa Tenggara General Hospital in Lombok. Result There were 33 patients who fulfill the inclusion and exclusion criteria in this study. Most of the patients are male with male and female ratio 3:1. The youngest patient age is eight years old, on the other hand, the oldest is 70 years old with the average age 46,6 years old. According to histopathology finding, on this study researcher didn't found WHO type I and most the patients were WHO type III (89,9 %). The mean blood urea nitrogen concentration before chemotherapy is 25,00 and after the treatment 33,33 with the p-value 0,01 with the paired t-test. On the other hand, creatinine serum level before and after chemotherapy consecutively 0,99 and 1,10. p-value 0,15, or there is no significant difference. Conclusion Blood urea nitrogen and creatinine serum are increase after cisplatin-based chemotherapy. However, only BUN has a significant difference.

scholarly journals The Effect of Geogebra on Students’ Conceptual and Procedural Knowledge: The Case of Applications of Derivative

2017 ◽  
Vol 7 (2) ◽  
pp. 67 ◽  
Author(s):  
Mehmet Fatih Ocal
Keyword(s):  
Conceptual Knowledge ◽  
Teaching And Learning ◽  
Procedural Knowledge ◽  
Dynamic Geometry ◽  
The Other ◽  
Control Group ◽  
Other Hand ◽  
Significant Difference ◽  
Before And After ◽  
Post Test

Integrating the properties of computer algebra systems and dynamic geometry environments, Geogebra became an effective and powerful tool for teaching and learning mathematics. One of the reasons that teachers use Geogebra in mathematics classrooms is to make students learn mathematics meaningfully and conceptually. From this perspective, the purpose of this study was to investigate whether instruction with Geogebra has effect on students’ achievements regarding their conceptual and procedural knowledge on the applications of derivative subject. This study adopted the quantitative approach with pre-test post-test control group true experimental design. The participants were composed of two calculus classrooms involving 31 and 24 students, respectively. The experimental group with 31 students received instruction with Geogebra while the control group received traditional instruction in learning the applications of derivative. Independent samples t-test was used in the analysis of the data gathered from students’ responses to Applications of Derivative Test which was subjected to them before and after teaching processes. The findings indicated that instruction with Geogebra had positive effect on students’ scores regarding conceptual knowledge and their overall scores. On the other hand, there was no significant difference between experimental and control group students’ scores regarding procedural knowledge. It could be concluded that students in both groups were focused on procedural knowledge to be successful in learning calculus subjects including applications of derivative in both groups. On the other hand, instruction with Geogebra supported students’ learning these subjects meaningfully and conceptually.

scholarly journals Prediction of Foetal Well-being with Non-stress Test

2016 ◽  
Vol 33 (2) ◽  
pp. 65-69
Author(s):  
Jahanara Rahman ◽  
Hosne Ara Begum
Keyword(s):  
Caesarean Section ◽  
Vaginal Delivery ◽  
Gestational Age ◽  
Apgar Score ◽  
Stress Test ◽  
The Other ◽  
P Value ◽  
Mild Depression ◽  
Other Hand ◽  
Significant Difference

Introduction: Non-stress test (NST) is the most common antenatal test performed to assess the foetus at risk of intrauterine hypoxia. On the other hand non-reactivity detected by NST increases the interferences of pregnancy by Caesarean section.Methodology: A cross sectional descriptive study was carried out in the department of Obstetrics and Gynaecology at Dhaka National Medical College between July2007 and June 2008.Objectives: The objectives of the study were (1) To observe the mode of delivery in cases of non-reactive non stress test (NST) and (2) To evaluate perinatal outcome of non-reactive NST.Results: A total 137 high risk pregnant women were included in the study. Age of the women ranges from 16 to 32 years. The mean age of the women was 23.74 ± 3.71 year. Among them 44.53% were primaegravida and 55.47% were multigravida. Gestational age was between 35 and 42 weeks and mean gestational age was 38.34±1.42 weeks. Regarding foetal reactivity 61.3% (n=84) were reactive and 38.7 % (n=53) were non-reactive. Among the babies of non reactive NST 98.11% and 1.89% were delivered by caesarean section and vaginal delivery respectively. Whereas, 48.81% and 51.19% babies of reactive NST were delivered by caesarean section and vaginal delivery respectively. The percentage of caesarean section was much higher in non-reactive NST cases in comparison to that of reactive NST which was statistically highly significant (p value 0.0000). One minute after birth APGAR scoring revealed that 56.6% and 43.4% newborn of non-reactive NST had no depression( APGAR score 7-10) and mild depression ( APGAR score 4-6) respectively. On the other hand 65.47% and 34.5% newborn of reactive NST had no depression and mild depression respectively at one minute after birth. Therefore, small difference was noticed in the neonatal status between the reactive and non-reactive NST which had no statistical significance (p value 0.507). Evaluation of the neonates with APGAR scoring done 5 minutes after birth revealed mild depression (APGAR score 4-6) in 24.53% and 20.24% of non-reactive and reactive NST cases respectively and no depression (APGAR score 7- 10) was found in 75.47% and 70.76% in reactive and nonreactive NST respectively. So, 5 minutes after birth the neonatal status among reactive and non-reactive NST made no significant difference (p value 0.9266).Conclusion: Neonatal evaluation revealed that all foetuses were not compromised as detected by NST. Relying on NST the rate of Caesarean section has been increased. Reassessment of the foetal conditions was needed with the help of other techniques. Therefore NST alone is insufficiently predictive of neonatal outcome.J Bangladesh Coll Phys Surg 2015; 33(2): 65-69

scholarly journals Comparison between Ormeloxifene and Norethisterone in reducing menorrhagia in dysfunctional uterine bleeding

2018 ◽  
Vol 7 (12) ◽  
pp. 4966
Author(s):  
Swati Gett ◽  
Shruti Singh
Keyword(s):  
Endometrial Thickness ◽  
Mean Value ◽  
Uterine Bleeding ◽  
The Other ◽  
P Value ◽  
Loss Assessment ◽  
Dysfunctional Uterine Bleeding ◽  
Significant Difference ◽  
Before And After

Background: Dysfunctional Uterine Bleeding (DUB) is a condition that affects nearly every woman at some point in her life. This study aims to compare the efficacy of Ormeloxifene and Norethisterone in reducing menorrhagia in such patients.Methods: This prospective study was done on 100 women presenting with dysfunctional uterine bleeding, of 20-50 years of age, who were ready for follow-up and were allocated into two equal groups, one was given Ormeloxifene and the other was given Norethisterone for a period of 3 months. Haemoglobin levels, endometrial thickness on ultrasound and Pictorial Blood loss Assessment Chart (PBAC) scores were assessed before and after the treatment.Results: It was found that both Ormeloxifene and Norethisterone reduced menorrhagia, with a significant difference in PBAC scores (p value <0.05). There was a notable reduction in PBAC scores in Ormeloxifene group (66.53% change from pretreatment mean value) as compared to Norethisterone group (31.38% change from pretreatment mean value); and same holds true for the change in haemoglobin levels as well as endometrial thickness. Ormeloxifene was found to have a greater effect on heavy menstrual bleeding in comparison to Norethisterone.Conclusions: Ormeloxifene is a new modality and is found to be a better option in reducing menorrhagia in DUB in respect to a greater success rate, better compliance and cost effectiveness.

scholarly journals Effects of Fluoride Release on Enamel Color Alteration

2017 ◽  
Vol 13 (24) ◽  
pp. 462
Author(s):  
Mahmoud Nabil El-Saafin ◽  
Firas Hadad ◽  
Victor Suciu ◽  
Marioara Moldovan ◽  
Mariana Pacurar
Keyword(s):  
Color Change ◽  
Statistical Significance ◽  
The Other ◽  
P Value ◽  
Fluoride Release ◽  
Adhesive Material ◽  
Universal Adhesive ◽  
Significance Level ◽  
Other Hand ◽  
Significant Difference

The aim of this study is to evaluate teeth discoloration after the usage of adhesive fluoride release. Material and Method: 80 extracted healthy premolars divided into two groups were used in the study, with metal brackets being bonded in both groups,. The first group universal adhesive was applied (transbond light cure adhesive paste-Transbond XT), whereas in the second group fluoride releasing bonding material was used (opal bond MV composite and opal seal). The measurement of color parameters was performed using the spectrophotometer vita easyshade 4.0 to calculate ΔL, Δa, Δb, and ΔE. Statistical Analysis: 3-way mixed analysis of variances (ANOVA) was used to compare ΔE before using adhesive material and after the procedure. On the other hand, it was used to compare Δa, Δb, and ΔL before and after using adhesive material. The statistical significance level was established at P< 0.05. Boferroni correction was used to create mean differences between the results. Results: The result of this study showed that ΔE* values were increased in all groups. The mean difference of ΔE* value in the first group (3M adhesive material) was 2.54± 1.57. At the same time, the ΔE value in opal adhesive group was 4.43±5.4. These results showed that fluoride seal had direct effect on enamel color after a period of three months teeth storage. Results showed above the normal limit and produced visible color change on the surface of the teeth after finishing procedure. On the other hand, ΔL values were increased in both groups, with a significant difference in the first group (p value 0.04) and with no significant difference in the second group (p value 0.239). Conclusion: The highest color changes were observed after the finishing procedure in opal bond MV composites and the opal seal groups. This was done by increasing ΔE value due to the presence of fluoride release adhesive structure. Transbond light cure adhesive past-Transbond XT had acceptable clinical change after the debonding and finishing procedure by increasing ΔE value.

scholarly journals Combination of Deep Breathing Relaxation and Murottal Reducing Post Chemotherapy Nausea Intensity in Nasopharyngeal Cancer (NPC) Patients

2020 ◽  
Vol 3 (1) ◽  
pp. 24 ◽  
Author(s):  
Agus Suryono ◽  
Fredi Setia Nugraha ◽  
Fakhruddin Akbar ◽  
Yunie Armiyati
Keyword(s):  
Breast Cancer ◽  
Research Method ◽  
Nasopharyngeal Cancer ◽  
Common Type ◽  
P Value ◽  
Test Design ◽  
Deep Breathing ◽  
Significant Difference ◽  
Before And After ◽  
Post Test

Nasopharyngeal Cancer (NPC) is the 3rd most common type of cancer in Indonesia after cervical and breast cancer. The method for controlling the growth of cancer cells is chemotherapy which has side effects of nausea. Post-chemotherapy nausea makes the patient uncomfortable and if not treated properly will cause complications. Management of nausea can be done with a combination of deep breathing relaxation and murottal.  The objective of the study to analyze the effect of a combination of deep breathing relaxation and murottal on the intensity of nausea in NPC patients after chemotherapy. The research method was a quasi-experiment one group pre-post-test design on 30 samples of post-chemotherapy NPC patients.  The results of the study showed that nausea intensity before and after given a combination of deep breathing and murottal obtained p-value 0,000 (p-value <0.05). There is a significant difference between nausea intensity before and after the combination of deep breathing and murottal relaxation. The combination of deep breathing and murottal breathing can reduce the intensity of nausea in NPC patients after chemotherapy.

scholarly journals Improvement of renal profile in Gentamicin-induced Nephrotoxicity in albino wistar rats by edible macrofungi Dacryopinax spathularia and Schizophyllum commune

2019 ◽  
Vol 11 (2) ◽  
pp. 436-439
Author(s):  
Amar Kumar ◽  
Manoj Kumar ◽  
Sukumar Dandapat ◽  
Rakesh Ranjan ◽  
M. P. Sinha
Keyword(s):  
Renal Function ◽  
Body Weight ◽  
Uric Acid ◽  
Blood Urea Nitrogen ◽  
Wistar Rats ◽  
Renal Damage ◽  
Schizophyllum Commune ◽  
The Other ◽  
High Dose ◽  
Urea Nitrogen

he present work has been taken to assess the pharmacological efficacy of two edible macrofungi Dacryopinax spathularia and Schizophyllum commune in the improvement of renal profile of Gentamicin-induced nephrotoxicity in albino wistar rats. The intra-peritoneal administration of gentamicin 80 mg/Kg Body Weight per day had resulted in alterations in renal function and renal damage which was reflected by abnormal and significant (p=0.05) increase in renal function parameters of blood like Urea, Creatinine, Uric Acid and Blood Urea Nitrogen (BUN). On administration of high dose (500 mg/Kg BW) of D. Spathularia extract to the nephrotoxic group of rats the concentration of urea, creatinine, uric acid and BUN significantly decreased from 104.26±7.45 to 76.27±7.24, 1.17±0.43 to 0.68±0.47, 3.68±1.34 to 2.58±0.56 and 48.72±4.36 to 31.14±3.76 respectively, in comparison to the nephrotoxic group of rats. On the other hand, the administration of high dose (500 mg/Kg BW) of S. commune extract to the nephrotoxic group of rats resulted into significant (p=0.05) decrease in the concentration of urea, creatinine, uric acid and BUN, from 104.26±7.45 to 51.42±6.15, 1.17±0.43 to 0.62±0.14, 3.68±1.34 to 2.36±0.74 and 48.72±4.36 to 28.65±3.85 respectively, in comparison to the nephrotoxic group of rats. The results also revealed that S. commune extract showed comparatively more efficacy in the renal profile improvement of nephrotoxic rats in comparison to the D. spathularia extract.

Effectiveness of Virtual Resilience Training on Assertiveness in Student Girls Aged 9–10 Years: A 1-Month Follow-Up

2021 ◽  
pp. 105984052110135
Author(s):  
Shima Gadari ◽  
Jamile Farokhzadian ◽  
Parvin Mangolian Shahrbabaki
Keyword(s):  
Experimental Study ◽  
Internal Stress ◽  
Intervention Group ◽  
The Other ◽  
Hormonal Changes ◽  
Emotional Instability ◽  
Other Hand ◽  
Significant Difference ◽  
Resilience Training

Girls between the ages of 9 and 10 begin to experience physical, physiological, and hormonal changes that may lead to internal stress. At this age, children are struggling for autonomy; on the other hand, they may experience emotional instability, and for these reasons, they may be vulnerable in many ways. This experimental study aimed to investigate the effect of resilience training on assertiveness in student girls aged 9–10. Data were collected before, immediately after, and 1 month after the intervention in the control ( n = 40) and intervention ( n = 37) groups. There was a significant difference between the assertiveness of the intervention immediately (26.80 ± 3.73) and 1 month after the intervention (27.05 ± 3.73), and assertiveness significantly increased in the intervention group ( p = .0001). Resilience training leads to improvements in assertiveness in student girls aged 9–10.

scholarly journals Correlation between vitamin D serum level and total IgE in asthmatic children

2020 ◽  
Vol 12 (2) ◽  
pp. 37-45
Author(s):  
Vesna Micevska ◽  
Tatjana Jakovska Mareti ◽  
Ilija Kirovski ◽  
Olivera Jordanova
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
P Value ◽  
Healthy Children ◽  
Total Ige ◽  
Asthmatic Children ◽  
Significant Difference ◽  
Children With Asthma ◽  
The Mean ◽  
Chronical Disease

Asthma is a chronical disease of the airways characterized by reversible obstruction of the bronchi and airway inflammation. In recent decades, the scientific interest of the vitamin D system and its role in development of asthma and other alergic diseases has been increased. Aims of this study are to mesure and compare the serum level of 25 OHD in asthmatic and healthy children and corelate the level of 25OHD and total IgE in asthmatic children. This prospective study includes 70 children at age 2 to 14, of which 32 are children with diagnosed asthma and 38 healthy children. In both  of the groups the serum level of 25 OHD was measured  and by the results 18 % of the healthy children (C) and 28% of the asthma children (E) had 25OHD  deficiency, 45%  of C and 50% of E were insufficient and 37 % of C / 22% of E were with normal 25 OHD serum level. The mean level of 25OHD in C was 27,83 +/- 10,24 and in E 20,9 ng/ml +/- 10,72. The mean levels in both groups had statistic significant difference with p-value < 0,05. According to age no statistic significant difference was found in both of the groups. There was a statisticaly significant decreased serum level of 25 OHD in asthmatic females.In the examined group (children with asthma) there was a negative linear correlation (association) of the level of 25OHD and total IgE serum level with r=- 0,55  Vitamin D serum level measurements in asthma patients gives the possibility for discovering the connection between its deficiency and development of asthma symptoms.

scholarly journals EFFECT OF MINDFULNESS INTERVENTION ON THE INTENSITY OF PAIN IN NASOPHARINGEAL CANCER PATIENTS UNDERGOING RADIATION TREATMENT

2018 ◽  
Vol 4 (2) ◽  
pp. 195-201
Author(s):  
Anna Jumatul Laely ◽  
Awal Prasetyo ◽  
Chandra Bagus Ropyanto
Keyword(s):  
Cancer Patients ◽  
Radiation Treatment ◽  
Nasopharyngeal Cancer ◽  
Psychological Trauma ◽  
Control Group ◽  
Intensity Level ◽  
Control Group Design ◽  
Mindfulness Intervention ◽  
Significant Difference ◽  
Before And After

Background: Physical responses that occur in patients with nasopharyngeal cancer are the emergence of pain due to the effects of treatment. The problem of pain in these patients at the stage of treatment remains critical to solve because it can cause comorbidity, psychological trauma and mortality. Mindfulness intervention is considered useful in transforming consciousness into the stage of acceptance.Objective: This study aims to determine the effect of mindfulness intervention on the intensity of pain in nasopharyngeal cancer patients undergoing radiation treatment.Methods: This was a quasy-experimental study with pretest posttest control group design. Thirty patients were selected using consecutive sampling, which divided into experiment and control group. Visual Analogue Scale (VAS) was used to measure pain. Each respondent received mindfulness intervention for 6 sessions, divided into 3 meetings. Paired t-test was used for data analysis.Results: The results showed a significant reduction of pain from 4.12 (moderate pain) to 3.06 (mild pain) in the experiment group. There was a significant difference in pain level before and after mindfulness intervention (p= 0.001).Conclusion: Mindfulness is effective in reducing pain intensity level in nasopharyngeal cancer patients undergoing radiation therapy.

scholarly journals PENGARUH TERAPI AKUPRESUR TERHADAP PENINGKATAN PRODUKSI ASI PADA IBU POST PARTUM DI PKU MUHAMADIYAH BANTUL

2020 ◽  
Vol 8 (4) ◽  
pp. 416
Author(s):  
Anita Liliana ◽  
Melania Wahyuningsih
Keyword(s):  
Breast Milk ◽  
Milk Production ◽  
Post Partum ◽  
Control Group ◽  
P Value ◽  
Breast Milk Production ◽  
Significant Difference ◽  
Before And After ◽  
Increase Milk Production ◽  
Postpartum Mothers

Abstract Adequacy of milk production in the newborns will affect the success of exclusive breastfeeding. Not all postpartum mothers are able to increase milk production in the postpartum period. Acupressure at the meridian points is one way to increase milk production in postpartum mothers. This study aims to determine the effect of acupressure therapy on increasing breast milk production in postpartum mothers at PKU Muhamadiyah Bantul. This study was a quantitative study  a quasi-experimental research design with pre-test and post-test nonequivalent control group. The number of respondents in each group was 17 people. The treatment given was acupressure at the meridian points for 5 minutes on days 2 and 3of poatpartum. Breastfeeding adequacy was assessed before treatment and on day 4 postpartum. Data were analyzed by Mc Nemar analysis. The results showed that there was a significant difference in breast milk production before and after acupressure with p value of 0.000 (p value <0.05). There was a significant difference in breast milk production in the control group before and after being given the breastfeeding technique leaflet p value 0.001 (p value <0.05). Conclusion: There is no significant difference in breast milk production after being given acupressure and after being given leaflets about breastfeeding techniques at PKU Muhamadiyah Bantul p value 0.100 (p value> 0.05).  Keywords: acupressure, breast milk production, postpartum

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