scholarly journals Relationship of HbA1c to Diabetic Retinopathy in Type 2 DM Patients at Haji Adam Malik General Hospital 2017-2018

2021 ◽  
Vol 3 (3) ◽  
Author(s):  
Yuni Silalahi ◽  
Ricke Loesnihari

Diabetic retinopathy is a microvascular complication of diabetes mellitus. This complication can occur due to hyperglycemia that occurs in blood vessels for a long period of time. To determine whether there is a relationship between HbA1c levels on the incidence of diabetic retinopathy on pationts with type 2 diabetes mellitus in Haji Adam Malik General Hospital Medan period of 2017 until 2018. This research is an analitical study with retrospective method (case control) and conducted at the General Hospital of Haji Adam Malik Medan. Data collection was performed on medical records of diabetic retinopathy patients at Haji Adam Malik General Hospital Medan in the period January 2017 to December 2018. Data were collected by using medial records of patients with simple random sampling technique with a total sample is 46 samples, 23 samples of diabetic retinopathy, and 23 samples that were not diabetic retinopathy. The results of this study indicate that of 23 diabetic retinopathy samples, 2 of them had controlled HbA1c and the other 21 are not controlled. As well as of the 23 samples were not diabetic retinopathy, 5 of them had HbA1c controlled HbA1c and 18 were uncontrolled. The result of the analysis with chi square test showed no relationship between HbA1c levels to the incidemce of diabetic retinopathy in Type 2 DM patients with a p value of 0,06. From this study it was found that there was no relationship between HbA1c levels and the incidence of diabetic retinopathy for Haji Adam Malik General Hospital in the 2017-2018 period.

Author(s):  
Vinay Kumar G. ◽  
Usha N. S. ◽  
Sandyashree B.

Background: Diabetes is major cause of morbidity and mortality worldwide. It is among the top 10 causes of death in adults. There are number of factors that influence the development of Type 2 DM, the most influential are lifestyle behaviors commonly associated with urbanization. Affordable, quick and easily available validated tools are required for assessment of risk factors for type 2 DM .Using one such questionnaire tool we have conducted a descriptive study in OPD patients of JSS hospital Chamarajanagara to identify and assess the risk of development of Type 2 DM. Objective: The objective of the study is to assess the risk of developing Type 2 diabetes mellitus among OPD patients attending at JSS hospital Chamarajanagara and to find the association between risk of developing Type 2 diabetes mellitus among OPD patients attending at JSS hospital chamarajanagara with their selected personal variables Methodology: Questionnaire on demographic profoma. Finnish diabetes risk score was used to collect data. An explorative descriptive method has been adopted and 90 patients were selected for the study using simple random sampling technique Results: The result of the study revealed that 51.1% of participants have moderate risk, 33.3% of participants have high risk and 15.6% of participants have slightly elevated risk. Conclusion: The participants of this study have moderate risk of getting type 2 DM and Gender, Age, Occupation and BMI are significantly associated in contributing the risk of developing type 2 DM.


2019 ◽  
Vol 4 (1) ◽  
pp. 14
Author(s):  
Rika Meldy Agustina ◽  
Noor Diani ◽  
Agianto Agianto

Introduction: In patients with type 2 diabetes mellitus (DM), sufficient knowledge and behavior are important for adherence to the lifelong treatment. The aim of this study is to measure the correlation between knowledge and behavior about the treatment of DM in diabetic patients in Kelurahan Cempaka.Methods: This is a cross-sectional study using a simple random sampling technique, with a total of 60 participants. We used a questionnaire on patients’ knowledge and behavior pertaining the treatment of type 2 DM.Result: From this study, we found that there is a significant correlation between knowledge and behaviour regarding the treatment in patients with type 2 DM (p<0.001).Conclusion: Knowledge has an important role in tailoring people’s behavior to carry out appropriate treatment in order to optimize the health status.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xujia Liu ◽  
Zehua Jiang ◽  
Guihua Zhang ◽  
Tsz Kin Ng ◽  
Zhenggen Wu

Abstract Background Genetic association of uncoupling proteins (UCPs) variants with the susceptibility of diabetic retinopathy (DR) in diabetes mellitus (DM) patients has been reported but with controversy. Here we aimed to conduct a meta-analysis to confirm the association of different UCPs variants with DR. Methods Three databases (Medline Ovid, Embase Ovid and CENTRAL) were applied in the literature search. Five genetic models, including allelic, homozygous, heterozygous, dominant and recessive models, were evaluated. Odds ratios (OR) were estimated under the random or fixed-effects models. Subgroup analyses, publication bias and sensitivity analyses were also conducted. Results Eleven studies on 2 UCPs variants (UCP1 rs1800592 and UCP2 rs659366) were included. Our meta-analysis showed that UCP1 rs1800592 was not associated with DR in type-2 DM patients, and UCP2 rs659366 also showed no association with DR. In the subgroup analyses on the stage of DR, allele G of UCP1 rs1800592 significantly increased the susceptibility of proliferative diabetic retinopathy (PDR) in type-2 DM patients in the allelic (OR = 1.26, P = 0.03) and homozygous models (OR = 1.60, P = 0.04). Subgroup analysis on ethnicity did not found any significant association of rs1800592 and rs659366 with DR. Conclusion Our meta-analysis confirmed the association of UCP1 rs1800592 variant with PDR in patients with type-2 DM, suggesting its potential as a genetic marker for PDR prediction in population screening.


e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Rixi Gahung ◽  
Karel Pandelaki ◽  
Emma Sy. Moeis

Abstract: Diabetes mellitus is still increasing in number in the future. Type 2 diabetes mellitus type 2 (T2DM) often appears in adults and the cause is due to a shortage of the hormone insulin on a relative basis, generally appears slowly and gradually worsens. One of the parameters to control blood sugar level is HbA1c. The high HbA1c increases the risks and complications in T2DM patients. This study aimed to obtain the relationship between HbA1c level and GFR among T2DM patients. This was an analytical study using the patient's medical record data. This study was conducted at the Endocrine Clinic and Heart and Hypertension Clinic with a total samples of 65 patients. The results showed that of the 65 subjects, there were 40 male patients and 25 female patients. The Pearson correlation test showed that the relationship of the HbA1c level and GFR had a p value = 0.05 > 0.462 and the correlation r = 0.093. Conclusion: There was no significant relationship between HbA1c level and GFR in type 2 DM patients. Keywords: HbA1c, GFR, type 2 DM Abtsrak: Diabetes merupakan suatu penyakit tidak menular yang akan terus meningkat jumlahnya di masa datang. Diabetes Melitus tipe 2 (DMT2) sering muncul pada orang dewasa dan penyebabnya oleh karena kekurangan hormon insulin secara relatif , umumnya muncul perlahan dan secara bertahap akan bertambah berat. Salah satu parameter kontrol kadar gula darah ialah HbA1c. Jika HbA1c meningkat terjadi pula peningkatan resiko komplikasi. Penelitian ini bertujuan untuk mengetahui hubungan kadar HbA1c dengan eLFG pada pasien DMT2. Jenis penelitian ini analitik dengan mengevaluasi data rekam medik pasien. Penelitian dilakukan di Poliklinik Endokrin dan Poliklinik Jantung dan Hipertensi dengan jumlah subyek penelitian 65 pasien DMT2. Hasil penelitian ini menunjukkan bahwa dari 65 orang subjek terdapat 40 laki-laki dan 25 perempuan. Untuk mengetahui adanya hubungan kadar HbA1c dengan LFG digunakan analisis bivariat Pearson correlation yang mendapatkan nilai p hitung = 0,462> 0,05 dengan kekuatan korelasi r = 0,093. Simpulan: Tidak terdapat hubungan bermakna antara kadar HbA1c dengan eLFG pada pasien DM tipe 2.Kata kunci: HbA1c, eLFG, DM tipe 2


2020 ◽  
Vol 8 (2) ◽  
pp. 66-72
Author(s):  
Angiesta Pinakesty ◽  
Restu Noor Azizah

Introduction: Diabetes mellitus (DM) is a non-communicable disease that has increased from year to year. Type 2 diabetes mellitus is not caused by lack of insulin secretion, but is caused by the failure of the body's cells to respond to the hormone insulin (insulin resistance). Insulin resistance was found to be a major contributor to atherogenic dyslipidemia. Dyslipidemia in DM risks 2 to 4 times higher than non-DM. Although dyslipidemia has a great risk for people with type 2 diabetes mellitus, this conventional risk factor only explains a portion (25%) of excess cardiovascular risk in type 2 DM. Discussion: In uncontrolled type 2 DM patients, LDL oxidation occurs faster which results from an increase in chronic blood glucose levels. Glycemic control as a determinant of DM progressivity is determined through HbA1c examination. HbA1c levels are associated with blood triglyceride levels. Meanwhile, triglyceride levels are associated with total cholesterol and HDL cholesterol levels. HbA1c levels are also associated with LDL cholesterol levels. Conclusion: There is a relationship between lipid profile and the progression of type 2 diabetes mellitus.   Keywords: type 2 diabetes mellitus, dyslipidemia, HbA1c, glycemic control, lipid profile


2020 ◽  
Vol 8 (01) ◽  
pp. 52-69
Author(s):  
Nurul Kartika Sari ◽  
Rivan Firdaus

Background: Diabetes Mellitus (DM) cases increased by 776 cases from the previous year based on data from Abdul Wahab Sjahranie Regional Hospital. There are many changes that occur in the life of people with type 2 diabetes, such as stress, anxiety, anger, and feeling useless. These problems can be minimized if the patient also has the knowledge and ability as well as good self-efficacy to manage the disease by doing self-care. Aim: To analyze the factors associated with the self-efficacy of type 2 DM patients. Methods: a quantitative study with a cross sectional approach. The purposive sampling technique for Type 2 DM patients at Abdul Wahab Sjahranie Hospital Samarinda, totaling 60 respondents from September-October 2018. Results: showed a significant relationship between duration of suffering and self-efficacy of DM patients with a p value <0.001, and there was no significant relationship between age, sex, education level, knowledge, motivation and self-efficacy with a p value> 0.001. Conclusion: The duration of type 2 diabetes is related to the patient's self-efficacy ability.  


2018 ◽  
Vol 1 (1) ◽  
pp. 69
Author(s):  
Citra Windani Mambang Sari ◽  
Fitri Nurul Khotimah ◽  
Sri Pratiwi Hartati

Diet is one of the main factors related to various diseases including Diabetes Mellitus (DM). High carbohydrate, fat, protein, and low fiber diets can increase the risk of type 2 DM occurrence, especially in the patient’s family as a risk group. Previous research on students with DM families in Central Java still had a high-calorie food consumption pattern. The diversity of population, culture, and age may affect the results. Therefore, this study aimed to describe the diet in the family of patients with type 2 DM in the working area of Puskemas (Community Health Center) Garuda Bandung.This research used a quantitative descriptive method by purposive sampling technique. The respondents in this study involved 46 people who were the children of type 2 DM patients in the working area of Puskesmas Garuda. Dietary data obtained from the food record sheet for 3 days and was calculated using Nutrisurvey software in kilocalories (kcal) as the unit of measurement then the results were categorized based on Consensus Perkeni 2015. Data analysis was using frequency distribution.The results showed that 39 (84.8%) respondents in the diet category less than body requirements, 37 (80.4%) respondents in the category of sufficient carbohydrate intake, 39 (84.6%) respondents in the category of excess fat intake, 45 (97.8%) respondents in the category of adequate protein intake, and 41 (89.1%) respondents in the category of less fiber.The conclusions from this study that almost all families of patients with type 2 DM in the work area of Puskesmas Garuda were in the diet category less than body requirement but with the excess fat intake and less fiber. Based on these results, the nurses in Puskesmas are expected to optimize the outreach programs by addressing families of DM patients to make the diet as an attempt to prevent the risk in the family of patients with type 2 DM.Key words: Diet, DM patients’ families, food record. Gambaran Diet pada Keluarga Pasien Diabetes Melitus Tipe 2AbstrakDiet adalah salah satu faktor utama yang berhubungan dengan berbagai penyakit termasuk Diabetes Melitus (DM). Diet tinggi karbohidrat, lemak, protein, serta rendah serat dapat meningkatkan risiko kejadian DM tipe 2 terutama pada keluarga pasien sebagai kelompok berisiko. Penelitian sebelumnya pada mahasiswa dengan keluarga DM di Jawa Tengah masih memiliki pola konsumsi makanan yang tinggi kalori. Perbedaan populasi, budaya, serta usia mungkin akan mempengaruhi hasil. Oleh karena itu, tujuan penelitian ini untuk menggambarkan diet pada keluarga pasien DM tipe 2 di wilayah kerja Puskemas Garuda Kota Bandung.Penelitian ini menggunakan metode deskriptif kuantitatif dengan teknik purposive sampling. Responden dalam penelitian ini berjumlah 46 orang yang merupakan anak kandung pasien DM tipe 2 di Wilayah Kerja Puskesmas Garuda. Data diet diperoleh melalui lembar food record selama 3 hari dihitung mengunakan software Nutrisurvey dengan hasil ukur dalam kilokalori (kcal) yang kemudian hasilnya dikategorikan berdasarkan Konsensus Perkeni 2015. Analisis data menggunakan distribusi frekuensi.Hasil penelitian menujukkan bahwa sebanyak 39 (84,8%) responden dalam kategori diet kurang dari kebutuhan, sebanyak 37 (80,4%) responden dalam kategori asupan karbohidrat cukup, sebanyak 39 (84,6%) responden dalam kategori asupan lemak berlebih, sebanyak 45 (97,8%) responden dalam kategori asupan protein cukup, dan 41 (89,1%) responden dalam kategori serat kurang.Simpulan dari penelitian ini bahwa hampir seluruh keluarga pasien DM tipe 2 di wilayah kerja Puskesmas Garuda berada pada kategori diet kurang dari kebutuhan tetapi dengan asupan lemak berlebih dan serat yang kurang. Berdasarkan hasil tersebut, maka perawat puskesmas diharapkan dapat mengoptimalkan program luar gedung dengan menyasar keluarga penderita DM untuk menjadikan diet sebagai upaya untuk mencegah risiko DM pada keluarga pasien DM tipe 2.Kata kunci : Diet, food record, keluarga pasien DM.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Rosliana Dewi ◽  
Fanny Dwi Agustina ◽  
Johan Budhiana ◽  
Syiva Dwi Fatmala

Diabetes mellitus (DM) can cause physical and psychological changes for sufferers. Psychological changes include changes in self-concept and depression. Psychological changes can be treated with nonpharmacological therapies, one of which is five-finger relaxation technique. The research aimed to reveal the effect of five-finger relaxation technique on depression experienced by type 2 DM patients. The five-finger relaxation technique is one of the generalist relaxation techniques by recalling pleasant experiences. This research is a quasi-experiment. Samples of this research were 34 respondents whom were selected using purposive sampling.  The intervention was carried out once a day for 3 consecutive days.  In order to measure depression, a valid and reliable questionnaire of Indonesian version of the Beck Depression Inventory (BDI) was employed.  Data were analyzed using the Wilcoxon Test and the Mann-Whitney Test. The results showed the was a decrease in depression in the control group (p-value of 0.008) and the intervention group (p-value of 0.000) and there were differences in depression in the control group and the intervention group (p-value of 0.000). It can be concluded that there is an effect of five-finger relaxation technique on depression in type 2 DM patients<em>.</em>


Author(s):  
Shilpa Pal ◽  
Anita Sharma ◽  
Sagar Modi

Introduction: Patients with Type 2 Diabetes Mellitus (T2DM) are at higher risk to develop depression. Depression in turn adversely affects glycaemic control and increases the risk of diabetes-related complications and mortality. There is a large variation among Indian studies on prevalence of depression in T2DM and associated risk factors. Aim: To assess the prevalence, severity, and determinants of depression among patients with T2DM. Materials and Methods: The study was conducted at a Tertiary Care Hospital during February 2018-February 2019, in North-Indian state of Uttarakhand. Study subjects were patients with T2DM, age >18 years. Based on exclusion and inclusion criterias, a total sample of 290 patients were studied. Presence of depression was assessed using Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria. Hamilton Depression Rating Scale (HAM-D) was used to estimate the severity of depression. Unpaired t-test and Mann-Whitney U test were used to compare continuous variables between subjects with and without depression. Chi-Square test was used to analyse categorical data. Binary logistic regression analysis was used to study the association between likelihood of depression and predictor variables. Results: Among 290 (155 males and 135 females, mean age of all subjects 58.2±11.08 years) study subjects with T2DM, 64 (22.1%) were found to have depression using DSM-5 criteria. Out of these 64 patients with depression, 46 were detected to have mild depression, 14 moderate depression and 4 severe depression using HAM-D scale. Subjects with T2DM and depression had: higher proportion of females (62.5% vs. 42.0%; p-value 0.004); lower literacy level (53.1% vs. 67.3%; p-value 0.037); higher frequency of diabetic retinopathy (85.9% vs. 62.8%; p-value <0.001) and diabetic kidney disease (43.8% vs. 27.4%; p-value 0.013); higher Fasting Plasma Glucose (FPG) (217.7±94.62 vs. 190.0±76.45 mg/dL; p-value 0.040); and lower haemoglobin (10.8±2.49 vs. 11.7±2.37 gm/dL; p-value 0.010) compared to the subjects without depression. On binary logistic regression analysis, female gender (OR 2.457, 95% CI 1.368-4.413, p-value 0.003) and diabetic retinopathy (OR 3.842, 95% CI 1.788-8.255, p-value 0.001) remained significantly associated with likelihood of depression. Conclusion: Depression was present in one-fifth of the study subjects with T2DM. Majority of them had mild depression. Female gender and diabetic retinopathy were associated with increased likelihood of depression.


2020 ◽  
Vol 11 (2) ◽  
pp. 197
Author(s):  
Yanuarita Tursinawati ◽  
Arum Kartikadewi ◽  
Kamala Nuriyah ◽  
Setyoko Setyoko ◽  
Ari Yuniastuti

<p>Diabetes mellitus (DM) often give a macrovascular complication such as Peripheral arterial disease (PAD). Ankle-brachial index (ABI) is a sensitive and specific examination for PAD. Obesity can be a risk factor of PAD. Obesity can be classified by the BMI (Body Mass Index) classification. The purpose of this research is to analyze the relationship of BMI with ABI in Type 2 DM (T2DM) patients of Javanese ethnicity. This study was an observational analytic research with case-control design and used a purposive sampling technique. There were 40 case samples and 40 control samples. Data analysis used the Independent T-test and Chi-square test. There was a significant differences on age (p=0,000), METs (p-value=0,003), and ABI (p-value=0,002) between the two groups. In the DM group was found that most abnormal ABIs were found in the higher BMI, even though there was no significant correlation by the statistic (p-value=0,255). BMI contributed less to the ABI value of Javanese ethnic T2DM patients.</p>


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