scholarly journals Endothelin1 Levels in Pregnant Women with Severe Preeclampsia and Normal Pregnant Women

2017 ◽  
pp. 77
Author(s):  
Yosiana Wijaya ◽  
John JE Wantania ◽  
Bismarck J Laihad
Keyword(s):  
Pregnant Women ◽  
Normal Pregnancy ◽  
Severe Preeclampsia ◽  
Cross Sectional ◽  
Endothelin 1 ◽  
Significant Difference ◽  
The Mean ◽  
Spss Software ◽  
Literature Theory ◽  
Normotensive Pregnancy

Objective: To determine the ratio of serum endothelin-1 levels between severe preeclampsia and normotensive pregnancy. Methods: Observational analytic study using cross-sectional. Sixteen woman with normal pregnancy and sixteen others with severe preeclampsia who met the inclusion and exclusion criteria, were tested for ET-1. The serum was analyzed at Prodia Laboratory, Manado. The ET-1 level was examined using ELISA (R&D Systems, Inc., Minneapolis, MN 55413, USA). The data obtained was analyzed using SPSS software version 20.0.and discussions were held using the existing literature theory. Results: The mean and median levels of endothelin-1 plasma in patients with severe preeclampsia is 2:46 ± 1:44 pg/ml, 1:09 ±  0:26 pg/ml, whereas in normotensive pregnancy is 1:03 ±  0:26 pg/ml, 1.95 ± 1:44 pg/ml with p < 0:05 (0000). Conclusion: There was a significant difference between endothelin- 1 level in severe preeclampsia and normotensive pregnancies. [Indones J Obstet Gynecol 2017; 5-2: 77-82] Keywords: endothelin-1, normotensive, preeclampsia

scholarly journals Comparative Study of Ultrasound with Transvaginal Finger Examination in Diagnosis of Abnormal Position and Presentation of Fetal Head

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Batool Teimoori ◽  
Azar Khaefi Ashkzari ◽  
Farahnaz Farzaneh
Keyword(s):  
Pregnant Women ◽  
Abdominal Ultrasound ◽  
Cross Sectional Study ◽  
Fetal Head ◽  
Cross Sectional ◽  
Abnormal Position ◽  
Significant Difference ◽  
The Mean ◽  
Spss Software ◽  
Fetal Head Position

Background: Abnormal position and presentation are challenges for obstetricians in about 10% of all pregnancies. Objectives: The purpose of this study was to compare ultrasound with transvaginal finger examination in detecting abnormal position and presentation of fetal head. Methods: This was a cross-sectional study performed in Ali ibn-e Abitaleb Hospital of Zahedan in 2018. The women underwent vaginal finger examination in the first phase of delivery, and then trans-abdominal ultrasound was performed for pregnant women. All examinations and ultrasounds were performed by one person with the same ultrasound device. Data were analyzed with SPSS software. Results: In this study, 100 pregnant women were studied in the first phase of pregnancy. The mean age of the subjects was 24.7 ± 5.5 years old. Fetal head position was determined in 81 and 93% of women with vaginal examination and ultrasound, respectively. There was weak agreement (kappa = 0.416). Fetal presentation was determined by finger examination in 93% of cases and by ultrasound in 100% of cases. There was moderate agreement (kappa = 0.783). Conclusions: In general, the results of this study showed that there was no significant difference between ultrasound and finger examination in the presentation and position of fetal head.

scholarly journals PERBEDAAN KADAR ZINC SERUM PENDERITA PREEKLAMPSIA BERAT DENGAN KEHAMILAN NORMAL

2018 ◽  
Vol 2 (1) ◽  
pp. 44-52
Author(s):  
Ermawati Ermawati ◽  
Hafni Bachtiar
Keyword(s):  
Serum Zinc ◽  
Normal Pregnancy ◽  
Severe Preeclampsia ◽  
Cross Sectional ◽  
Increased Risk ◽  
Significant Difference ◽  
Maternal Morbidity And Mortality ◽  
Anti Oxidant ◽  
The Mean ◽  
Risk Of Preeclampsia

Preeclampsia is a major obstruction complication with increasing incidence and is associated with maternal morbidity and mortality. One theory regarding preeclampsia is the development of oxidative stress due to the benefits of pro-oxidant and anti-oxidant functions that consequently results in free radicals, active oxygen, or reactive nitrogen. The deacrease of Zinc as a cofactor of anti-oxidant enzymes is reported to be associated with an increased risk of preeclampsia. Cross sectional comparative study was conducted in Dr. M. DjamilPadangHospital, SolokDistrict Hospital, PainanDistrict Hospital, BatusangkarDistrict Hospital, and Biomedicallaboratoryof Medical Faculty of Andalas University from September 2014 to February 2015. There were 40 samples with pregnancy beyond 20 weeks which were then divided into two groups; severe preeclampsia and normal pregnancy. Serum zinc wasexamined in both groups. Serum zinc in severe preeclampsia and normal pre-stressed demonstrated a significant difference (p <0.05). The mean concentration of serum zinc in severe preeclampsia and in normal pregnancy were 0.45 ± 0.09 μg / ml and 0.78 ± 0.55 μg / ml with p = 0.02. This difference is statistically significant with p <0.005. There was a significant difference between serum zinc concentration in normal pregnant women and that in severe preeclamptic women.Keywords: severe preeclampsia, normal pregnancy, zinc serum

scholarly journals Maternal-Fetal Attachment and Domestic Violence in Iranian and Afghan Pregnant Women: A Cross-Cultural Study

2020 ◽  
Author(s):  
Mahlagha Dehghan ◽  
Hakimeh Ferdosi ◽  
Faroukh Abazari ◽  
Jamileh Farokhzadian
Keyword(s):  
Domestic Violence ◽  
Pregnant Women ◽  
Inverse Correlation ◽  
Psychological Violence ◽  
Cross Sectional ◽  
Afghan Women ◽  
Maternal Fetal Attachment ◽  
Significant Difference ◽  
The Mean ◽  
Fetal Attachment

Abstract Background: Domestic violence against pregnant women is becoming more frequent and intense. Studies have shown that women who were under more physical and psychological violence experienced a lot of stress and depression and had less ability to communicate with their fetuses. International statistics show a high prevalence of violence against Afghan women and the communities migrated to Afghanistan. Therefore, the present study aimed to compare the maternal-fetal attachment and domestic violence between Iranian and Afghan pregnant women.Methods: This study has a descriptive-comparative cross-sectional design. The study population consisted of Iranian and Afghan pregnant women referred to Kerman Health Centers in 2018-2019. One hundred-forty-six Iranian pregnant women and 142 Afghan pregnant women were enrolled in the study by the quota sampling. Data collection tools were demographic and clinical information questionnaire, questionnaires of domestic violence against women, and maternal-fetal attachment scale. Results: The mean score of maternal-fetal attachment in Iranian and Afghan pregnant women was higher than the average. Also, scores of maternal-fetal attachment and its dimensions in Afghan pregnant women were significantly higher than that of Iranian pregnant women (P < 0.001). The mean score of domestic violence was low in Iranian and Afghan pregnant women. There was no significant difference between Iranian and Afghan pregnant women in the total score of domestic violence (P > 0.05). There was a significant inverse correlation between maternal-fetal attachment and domestic violence in Iranian pregnant women (P < 0.05). In Afghan pregnant women, there was a positive and significant correlation between maternal-fetal attachment and sexual violence in while there was a significant and reverse relationship between other dimensions of attachment and violence (P < 0.05).Conclusion: This study showed that the rate of violence in the studied populations was low, and maternal-fetal attachment rate is appropriate. The relationship between violence and mother-fetal attachment had a different pattern in Iranian and Afghan women. Therefore, further studies are needed to investigate the factors affecting maternal-fetal attachment, especially in Afghan women.

scholarly journals Heme Oxygenase1 Level in Normotensive Pregnancy and Preeclampsia with Severe Features

2017 ◽  
pp. 128
Author(s):  
Christian Homenta ◽  
John J Wantania ◽  
Juneke J Kaeng
Keyword(s):  
Pregnant Women ◽  
Heme Oxygenase ◽  
P Value ◽  
Heme Oxygenase 1 ◽  
Cross Sectional ◽  
Whitney Test ◽  
Mann Whitney Test ◽  
Significant Difference ◽  
The Relationship ◽  
Normotensive Pregnancy

Objective: To understand the relationship of heme oxygenase-1 (HO-1) level between normotensive pregnancy and preeclampsia with severe features. Method: The cross sectional study was conducted in the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sam Ratulangi/Prof. Dr. R. D. Kandou General Hospital Manado. The subjects consisted of 26 pregnant women with normal blood pressure and 26 women with severe features of preeclampsia. We took the patients’ history, general physical examination, and laboratory assessment. The blood samples were taken from normotensive women more than 20 weeks of pregnancy and preeclamptic women with severe features more than 20 weeks of pregnancy. The data obtained was processed using SPSS 20.0 software. We did the nonparametric Mann-Whitney test to analyze the relationship between heme oxygenase-1 (HO-1) level in normotensive pregnancy and preeclampsia with severe features. Result: The level of heme oxygenase-1 (HO-1) in normotensive pregnant women was at 3.24 (SD 0.58) ng/ml (95% CI 3.00-3.47), and the level of heme oxygenase-1 (HO-1) of preeclamptic women with severe features was 3.92 (SD 0.73) ng/ml (95% CI 3.62-4.21). The result of Mann-Whitney test showed p value of 0.001 which meant that there was significant difference in the level of heme oxygenase- 1 (HO-1) between normotensive women and pre-eclamptic women with severe features. Conclusion: There was the relationship between the level of heme oxygenase-1 (HO-1) and the incidence of preeclampsia with severe features. Keywords: heme oxygenase-1 (HO-1), normotensive pregnancy, preeclampsia with severe features

Risk Factors of Preeclampsia among Pregnant Women in Khorramabad (West of Iran)

2020 ◽  
Vol 16 (4) ◽  
pp. 313-317
Author(s):  
Mahnaz Mardani ◽  
Farshad Teymouri ◽  
Maryam Rezapour
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Cross Sectional Study ◽  
Smoking History ◽  
Cross Sectional ◽  
Factors Associated ◽  
Significant Difference ◽  
Spss Software ◽  
Health Care Centers ◽  
Risk Of Preeclampsia

Background: Preeclampsia occurs in 2-10% of pregnancies, worldwide, and is characterized as a combination of hypertension and proteinuria. Objective: The purpose of this study is to determine the risk factors associated with the incidence of preeclampsia in the west of Iran and associated factors. Methods: This is a cross sectional study that was performed on 740 pregnant women between 2014- 2017, who were referred to different health care centers of Khorramabad. The data was collected from these centers and a questionnaire was filled for every woman that included age, height, gender of the neonate, number of pregnancies, multiparity, season of the pregnancy, birth weight, mothers’ body mass index (BMI) before delivery, smoking history and diagnosis of preeclampsia. The data obtained was statistically analyzed using SPSS software. Results: Of the 760 subjects included, 1.1% (8 cases) were reported to be presented with preeclampsia. We found a significant difference between non pre-eclamptic and pre-eclamptic patients in terms of BMI (p=0.006), number of pregnancies (p<0.05), maternal age (p<0.05) and weight (p=0.004). With an increase in BMI and the number of pregnancies, the risk of preeclampsia was elevated. Pre-eclamptic mothers had higher body weight than non-pre-eclamptic ones (75.9 kg vs. 65.6 kg) and the prevalence of preeclampsia increased with age. Conclusion: The prevalence of preeclampsia was seen to be positively associated with higher BMI, pregnancy rate, mother weight and age are associated with higher prevalence of preeclampsia.

scholarly journals PERBEDAAN RERATA FAKTOR HEMOSTASIS PADA PEB, EKLAMPSIA DAN KEHAMILAN NORMAL

2019 ◽  
Vol 3 (1) ◽  
pp. 27-36
Author(s):  
Yogi Syofyan ◽  
Joserizal Serudji ◽  
Hafni Bachtiar
Keyword(s):  
Normal Pregnancy ◽  
Cross Sectional Study ◽  
Severe Preeclampsia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Multiple Organs ◽  
Significant Difference ◽  
Keywords Pregnancy ◽  
Post Hoc ◽  
D Dimer

There will be multiple organs changes in preeclampsia and eclampsia. One of them is a change in hemostasis system which is platelet activation, extrinsic and intrinsic cascade reaction and increasing of fibrinolytic activation. This is a cross sectional study conducted at Obstetric and Gynecologic Departement of Medical Faculty of Andalas University/ M Djamil Central Hospital in Padang on July 2014 with the number of samples are 44 persons. Samples are divided into 3 groups: Severe preeclampsia, eclampsia, and normal pregnancy. Platelet, PT,APTT, and D-Dimer counting were conducted and statistic analyzed was done with Anova dan Post Hoc Bonferoni. The more severe pregnancy, the lower platelet count and PT, but the dif- ference is not statistically significant between three groups: severe preeclampsia, eclampsia, and normal pregnancy (p < 0,05). Mean of APTT and D-Dimer is statistically significant due to condition of pregnancy. Post Hoc Bonferroni analysis showed a significant difference of APTT mean in the eclampsia, severe pre-eclampsia, and normal pregnancy (p <0,05 ). D-Dimer Mean shows a significant difference between normal pregnancy, severe preeclampsia, and eclampsia (p <0,05).Keywords: Pregnancy condition, severe preeclampsia, eclampsia, normal pregnancy, platelet, PT, APTT, and D-Dimer

scholarly journals Serum Calcium Levels in Preeclampsia

2021 ◽  
pp. 127-131
Author(s):  
Feriha Fatima Khidri ◽  
Hina Riaz ◽  
Farah Naz ◽  
. Almas ◽  
Arsalan Ahmed Uqaili ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Serum Calcium ◽  
Calcium Concentration ◽  
Normal Pregnancy ◽  
Cross Sectional Study ◽  
Severe Preeclampsia ◽  
P Value ◽  
Cross Sectional ◽  
Mild Preeclampsia

Objectives: To determine the serum calcium levels in mild and severe preeclampsia and compare it with normal pregnancy. Methods: It was a comparative cross sectional study. Thirty five normotensive pregnant women, n=30 women with mild preeclampsia and n=70 with severe preeclampsia were recruited at Liaquat University of Medical and Health Sciences, Hospital. The serum calcium was measured and levels were compared among three groups. The data was analysed on SPSS v. 20. Results: The gestational age was more in the normal pregnancy compared to mild and severe preeclampsia (38.7±2.1 vs 36.7±3.6 and 36.2±2.8, p-value=0.0002). The calcium concentration was less in the both groups of preeclampsia i.e., 8.41± 0.96 mg/dl in mild and 8.02± 0.77 mg/dl in severe preeclampsia vs 9.2± 0.32 mg/dl in normal pregnant women, (p-value <0.001). Conclusion: We found lower levels of serum calcium in preeclampsia, suggesting its possible role in pathogenesis. Further studies to investigate the potential role of dietary supplementation of micronutrients during pregnancy are recommended.

scholarly journals Higher Cortisol Level Would Increase the Risk of Spontaneous Abortion

2016 ◽  
Author(s):  
Christian Sastra
Keyword(s):  
Spontaneous Abortion ◽  
Cortisol Level ◽  
Gestational Age ◽  
Normal Pregnancy ◽  
Equation Model ◽  
Cross Sectional ◽  
Significant Difference ◽  
Version 2.0 ◽  
The Mean ◽  
Logistic Regression Equation

Objective: To understand the correlation between cortisol level and spontaneous abortion in normal pregnancy with gestational age less than 20 weeks. Method: The study design was a correlative analytic prospective study with cross sectional observational approach. This study started from June 2012 until the number of participant sufficiently from Prof. Dr. R.D. Kandou General Hospital. The data then processed SPSS version 2.0, ROC and logistic regression equation model (chance model). Result: The study included 50 cases consisted of 25 spontaneous abortion cases and 25 normal pregnancies with gestational age less than 20 weeks, and got result if cortisol level for 18.52 μg/dl so spontaneously abortion chance for 35.7% and if cortisol level for 24.0 μg/dl would chance for spontaneous abortion for 99.3%. Conclusion: In this study, there was a significant difference in cortisol level in women with spontaneous abortion and < 20 weeks normal pregnancy. Higher cortisol level would increase spontaneous abortion risk. The mean cortisol level in spontaneous abortion was 27.28892 μg/dl. While the mean cortisol level in women with normal pregnancy was 11.7660 μg/dl. Analysis of the correlation between cortisol level and spontaneous abortion gave a cut off point for cortisol level of 19.1 μg/dl with sensitivity of 92% and specificity of 92%. [Indones J Obstet Gynecol 2013; 37-1: 17-20] Keywords: cortisol level, normal pregnancy, spontaneous abortion

scholarly journals The Mean Difference of Hemostatic Factors in Severe Preeclampsia and Eclampsia

2020 ◽  
Vol 4 (1) ◽  
pp. 22-27
Author(s):  
Dyhan Purna Setia ◽  
Ferdinal Ferry ◽  
Dovy Djanas
Keyword(s):  
Severe Preeclampsia ◽  
Research Subjects ◽  
Cross Sectional ◽  
Blood Electrolytes ◽  
Significant Difference ◽  
Hemostatic Factors ◽  
The Mean ◽  
The Difference ◽  
Near Term ◽  
Cross Sectional Design

The aim of this study was to see the difference in the mean ratio of sodium levels between pregnancy with severe preeclampsia and eclampsia. The method in this research is an analytical study using a cross sectional design. The research was conducted in the delivery room Dr. M. Djamil Padang from 15 January 2016 to 31 December 2017. There were 60 patients as research subjects, the sample was divided into 2 groups, namely severe preeclampsia (PEB) and eclampsia. Anamnesis and physical examination were then carried out to obtain data and clinical diagnosis. The data were recorded in a research form that had been provided, then the blood electrolytes were examined for sodium and potassium. Statistical analysis to assess meaning using the T-test. The results showed that in the PEB and Eclampsia groups, it was found that multiparity parity had the highest respondents. This is in accordance with the literature where the incidence of preeclampsia is more often found at gestational age near term. The conclusion of this study there was no significant difference in the mean sodium ratio between preeclampsia, PEB and eclampsia. Keywords: pregnancy condition, PEB, eclampsia, platelet, PT, APTT, and D-Dimer

scholarly journals PERBANDINGAN KADAR ZINC PADA PERSALINAN PRETERM DAN KEHAMILAN NORMAL

2018 ◽  
Vol 12 (3) ◽  
pp. 212
Author(s):  
Visti Delvina ◽  
Arni Amir ◽  
Ermawati Ermawati
Keyword(s):  
Preterm Labor ◽  
Normal Pregnancy ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
T Test ◽  
Cross Sectional ◽  
Consecutive Sampling ◽  
Significant Difference ◽  
The Mean ◽  
Zinc Levels

<p><strong><em>The Comparative   Zinc Levels in Preterm Labor and Normal Pregnancy</em></strong></p><h1 align="center"><em>ABSTRACT</em><em></em></h1><p><em> </em></p><p><em>               </em><em>Preterm labor occurs between 20 weeks and before 37 weeks of pregnancy. It is indicated by regular contractions of the uterus and it may cause the thinning and flattening of the cervix. Preterm labor also causes the high rates of perinatal morbidity and mortality. Deficiency zinc during pregnancy can stimulate the preterm labor. The design of this reseacrh was a comparative cross sectional study. It was conducted in Rasidin District Hospital, Siti Rahmah Hospital and Biomedical Laboratory, Faculty of Medicine, Andalas University, Padang on Februari 2017 to June 2018. There were 50 samples in this reseach. It was selected by consecutive sampling. The samples were divided into two groups: preterm labor and normal pregnancy. Zinc levels are examined by the ELISA method. Then, the data were analyzed by using the t test. The results of this reseach showed that the mean zinc level in the preterm labor group was 12.22 ± 0.41 μmol / L and 13.96 ± 0.64 μmol / L of the mean zinc level in the normal pregnancy group with P= 0.000. Moreover, statistical test inffered that there was significant difference between zinc levels in preterm labor and normal pregnancy. In short, it can be concluded that zinc levels group in the preterm labor were lower than the normal pregnancy group.</em><em></em></p><p><em> </em></p><p><em> </em></p><p><strong><em>Keywords</em></strong><em>: Zinc, Preterm Labor</em><em></em></p><p align="center"><em> </em></p><p><em> </em></p><p><em> </em></p><p><em> </em></p><p><em> </em></p><p><em> </em></p><p><strong><em>Perbandingan Kadar Zinc Pada Persalinan Preterm dan Kehamilan Normal</em></strong></p><h1 align="center"><em>ABSTRAK</em><em></em></h1><p><em> </em></p><p><em>Persalinan</em><em> </em><em>preterm adalah persalinan yang terjadi antara 20 minggu dan sebelum 37 minggu kehamilan yang ditandai</em><em> </em><em>adanya kontraksi teratur dari </em><em>uterus</em><em> </em><em>yang dapat</em><em> </em><em>menyebabkan</em><em> </em><em>penipisan dan pendataran</em><em> </em><em>serviks. Persalinan preterm menyebabkan tingginya angka morbiditas dan mortalitas perinatal. Defiseiensi zinc selama kehamilan dapat menstimulasi terjadinya persalinan preterm. Desain penelitian ini adalah cross sectional komparatif, penelitian dilakukan di RSUD Rasidin, RSI Siti Rahmah dan Laboratorium Biomedik Fakultas Kedokteran Universitas Andalas Padang pada bulan Februari 2017 – Juni 2018. Jumlah sampel sebanyak 50 yang dipilih secara consecutive sampling, yang dibagi menjadi dua kelompok yaitu persalinan preterm dan kehamilan normal. Kadar zinc diperiksa dengan metode ELISA. Data dianalisa menggunakan uji t test. </em><em>Hasil penelitian rerata kadar zinc pada kelompok persalinan preterm 12,22 ± 0,41 µmol/L dan rerata kadar zinc pada kelompok kehamilan normal adalah 13,96 ± 0,64 µmol/L dengan nilai p 0,000. Secara statistik terdapat perbedaan yang bermakna antara kadar zinc  pada persalinan preterm dan kehamilan normal. Kesimpulan, kadar zinc pada kelompok persalinan preterm lebih rendah daripada kelompok kehamilan normal.</em><em></em></p><p><em> </em><em></em></p><p><em> </em></p><p><strong><em>Kata Kunci</em></strong><em> : Zinc, Persalinan Preterm</em></p>

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