scholarly journals The Mean Difference of Hemostatic Factors in Severe Preeclampsia and Eclampsia

2020 ◽  
Vol 4 (1) ◽  
pp. 22-27
Author(s):  
Dyhan Purna Setia ◽  
Ferdinal Ferry ◽  
Dovy Djanas

The aim of this study was to see the difference in the mean ratio of sodium levels between pregnancy with severe preeclampsia and eclampsia. The method in this research is an analytical study using a cross sectional design. The research was conducted in the delivery room Dr. M. Djamil Padang from 15 January 2016 to 31 December 2017. There were 60 patients as research subjects, the sample was divided into 2 groups, namely severe preeclampsia (PEB) and eclampsia. Anamnesis and physical examination were then carried out to obtain data and clinical diagnosis. The data were recorded in a research form that had been provided, then the blood electrolytes were examined for sodium and potassium. Statistical analysis to assess meaning using the T-test. The results showed that in the PEB and Eclampsia groups, it was found that multiparity parity had the highest respondents. This is in accordance with the literature where the incidence of preeclampsia is more often found at gestational age near term. The conclusion of this study there was no significant difference in the mean sodium ratio between preeclampsia, PEB and eclampsia. Keywords: pregnancy condition, PEB, eclampsia, platelet, PT, APTT, and D-Dimer

2019 ◽  
Vol 2 (1) ◽  
pp. 16-20
Author(s):  
Gunawan Efri ◽  
Dovy Djanas

Objective: To determine the difference in mean ratio of sodium content between pregnancy with severe preeclampsia and eclampsia.Method: This is an analytical study using a cross sectional study design. The study was conducted inMaternity room of Dr. M. Djamil Padang from January 15th, 2016 to December 31st, 2017, there were 60 patients as subjects, the sample was divided into 2 groups: severe preeclampsia and eclampsia. Furthermore, history and physical examination to obtain data and clinical diagnosis. Data is recorded in a research form that has been provided, then performed blood electrolytes of Sodium and Potassium. Statistical analysis to assess significance using T-test.Results: In the severe preeclampsia and eclampsia, multiparous parity had the highest respondent. This is consistent with the literature in which the incidence of preeclampsia is more common in late pregnancy.Conclusions: There was no significant difference in the mean sodium ratio between normal severe preeclampsia pregnancy and normal pregnancy.Keywords: pregnancy condition, severe preeclampsia, eclampsia, and sodium.


2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Berliana Irianti ◽  
Ermawati Ermawati ◽  
Arni Amir

Abstrak Penyebab dismenore belum semuanya diketahui, ada dugaan peningkatan proses peroksida lipid yang akan mengaktivasi mediator inflamasi pada endometrium yang menimbulkan rasa nyeri haid (dismenore). Tujuan penelitian ini adalah menentukan perbedaan kadar malondialdehide dan tromboksan B 2  pada dismenore dan tanpa dismenore. Studi observasional ini menggunakan desain potong lintang komparatif. Subjek penelitian terdiri dari dua kelompok yaitu 23 remaja dismenore dan 23 remaja tanpa dismenore dengan waktu penelitian dari Juni sampai Juli 2014. Analisis sampel dilakukan di Laboratorium Biomedik dan Biokimia Universitas Andalas Padang. Pemeriksaan kadartromboksan B 2  menggunakan metode ELISA dan kadar malondialdehide menggunakan metode Asam Thiobarbiturat (TBA). Hasil penelitian diperoleh bahwa rerata kadar malondialdehid pada remaja dengan dismenore yaitu 2,60±0,63 µmol/ml, rerata remaja tanpa dismenore 1,98±0,12 µmol/ml dengan probabilitas p<0,05 (0,000), sedangkan reratakadar Tromboksan B 2  pada remaja dengan dismenore 20,043±9,56 ng/ml, rerata remaja tanpa dismenore 19,222±10,79 ng/ml, dengan probabilitas p>0,05 (0,786). Kesimpulan penelitian ini adalah terdapat perbedaan yang signifikan rerata kadar malondialdehid pada remaja dengan dismenore dan tanpa dismenore dan tidak terdapatperbedaan signifikan pada kadar tromboksan B 2 pada remaja dengan dismenore dan tanpa dismenore.Kata kunci: remaja, dismenore, malondialdehide, tromboksan B2 Abstract The precise cause of dysmenorrhea is still unclear, there may be increased lipid peroxidation process will activate the inflammatory mediators at endometrium that cause menstrual cramps (dysmenorrhea). The objective of this study was to determine the difference of malondialdehyde levels and thromboxane B 2  levels in dysmenorrhea and without dysmenorrhea. It was an observational study with comparative cross-sectional design. The subjects consisted of two groups, they are 23 adolescent with dysmenorrhea and 23 adolescents without dysmenorrhea, done in Juny -July 2014. Sample analysis was conducted in Laboratory of Biochemistry and Biomedical Laboratory of Andalas University Padang. The examination of Thromboxane B 2  levels used ELISA and the examination of malondialdehyde levels used a Thiobarbituric acid method. The results showed the mean of malondialdehyde levels in adolescents withdysmenorrhea was 2.60±0.63 µmol/ml, the mean level in adolescent without dysmenorrhea was 1.98±0.12 µmol/ml with probability p<0.05 (0.000), while the mean levels of thromboxane B 2  in adolescents with dysmenorrhea was 20.043±9.56 ng/ml, the mean level in adolescent without dysmenorrhea was 19.222±10.79 ng/ml, with probabilityp>0.05 (0.786). It can be concluded that there is a significant difference in the mean of malondialdehyde levels between adolescents with dysmenorrhea and without dysmenorrhea and there is no significant differences in thromboxane B 2 level between adolescents with dysmenorrhea and without dysmenorrheaKeywords: adolescent, dysmenorrhea, malondialdehyde, thromboxane B2


2021 ◽  
Vol 7 (1) ◽  
pp. 16-18
Author(s):  
Yuni Selfiana Br. Sembiring ◽  
Rudyn Reymond Panjaitan ◽  
Kristo A Nababan

Background: Acne vulgaris is a disease of the pilosebaceous unit that often occurs in adolescents and young adults. The pathogenesis of acne vulgaris involves several factors, one of which is the acidity (pH) of the skin.  Objective: This study aimed to determine the difference in the degree of acidity of facial skin, chest and back of patients with acne vulgaris.  Methods: This was a comparative analytic study with cross sectional design. The sample collection technique was consecutive sampling. Data were analyzed using ANOVA-test.  Results: The majority of patients with acne vulgaris who came to Murni Teguh Memorial Hospital Medan and the private clinic of dr. Rudyn Reymond Panjaitan, M.Ked (KK), Sp.KK was a 17-25 year old. The mean acidity of facial skin with acne vulgaris was 5.66, the mean acidity of chest skin was 5,84 and the mean acidity of back skin was 6.09. There was a significant difference in the mean value of acidity in facial, chest and back skin of patients with acne vulgaris (p = 0,000). Conclusion: There is a significant difference in average degree of acidity on the facial, chest and back skin in patients with acne vulgaris.


2019 ◽  
Vol 2 (1) ◽  
pp. 10-15
Author(s):  
Dyhan Purna Setia ◽  
Ferdinal Ferry ◽  
Dovy Djanas

Objective : To find the difference in mean hemostatic factors in severe preeclampsia and eclampsia.Method : The study was analytic descriptive using a cross sectional study design by looking at the subject's Medical Record according to the time and place of research. The sample is the entire medical record of pregnant women who suffer from preeclampsia and eclampsia in the obstetric and gynecology departments of Dr. M. Djamil Padang Hospital in the period 15 January 2016 to 31 December 2017. The assessment was in the form of assessed platelet levels, PT, APTT and D-Dimer. Samples were taken from populations that met the inclusion criteria and did not have exclusion criteria. Sampling using consecutive sampling techniques taken from the Medical Record Dr. M.Djamil Padang. Statistical analysis to assess significance using the T-Test.Result : The severity the condition of pregnancy the lower the platelet mean and PT. Significant differences were obtained between platelets in PEB and eclampsia (p> 0.05). The mean PT, APTT and D-Dimer showed no significant differences in pregnancy conditions. Statistical test with T-Test did not show significant differences in mean PT, APTT, and D-dimer between eclampsia and PEB (p> 0.05).Conclusion : There were significant differences in mean in platelets, whereas in PT, APTT, and D-dimers in PEB and eclampsia there were no significant differences.Keywords: Pregnancy, severe preeclampsia, eclampsia, platelets, PT, APTT, D-Dimer.


2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Helen Evelina Siringoringo ◽  
Yusrawati Yusrawati ◽  
Eva Chundrayetti

AbstrakPreeklampsia-eklampsia sampai saat ini masih merupakan disease of theory. Kelainan yang terjadi pada penyakit ini adalah disfungsi endotel yang dapat disebabkan oleh perubahan kadar profil lipid. Tujuan penelitian ini adalah mengetahui perbedaan rerata kadar profil lipid pada preeklampsia dengan kehamilan normal pada etnik Minangkabau. Penelitian observasional dengan rancangan cross sectional ini dilakukan di RSUP dr. M. Djamil Padang, RS Reksodiwiryo Padang dan UPTD Laboratorium Kesehatan Daerah Sumatera Barat. Subjek terdiri dari 2 kelompok yang diambil secara consecutive sampling dengan jumlah masing-masing 27 orang. Pemeriksaan profil lipid dilakukan dengan metode kalorimetri. Analisis data dilakukan secara uji statistik independent t-test. Hasil penelitian diperoleh rerata kadar total kolesterol pada kelompok preeklampsia dan kehamilan normal adalah 270,19+68,955 mg/dL dan 247,56+44,415 mg/dL dengan nilai p=0,158, rerata kadar trigliserida pada kelompok preeklampsia dan kehamilan normal adalah 296,07±157,993 mg/dL dan 272,89±84,608 mg/dL dengan nilai p=0,504, rerata kadar HDL pada kelompok preeklampsia dan kehamilan normal adalah 51,93±19,882 mg/dL dan 63,33±11,222 mg/dL dengan nilai p=0,012, rerata kadar LDL pada kelompok preeklampsia dan kehamilan normal adalah 159±52,038 mg/dL dan 129,67±38,692 mg/dL dengan nilai p=0,023, rasio perbandingan LDL/HDL pada kelompok preeklampsia dan kehamilan normal adalah 3,86 dan 2,04. Dari hasil penelitian dapat disimpulkan pada kedua kelompok tidak ada perbedaan kadar kolesterol total dan trigliserida, tetapi ada perbedaan kadar HDL dan LDL , rasio perbandingan LDL/HDL lebih tinggi pada preeklampsia daripada kehamilan normal.Kata kunci: preeklampsia, total kolesterol, trigliserida, HDL, LDL, etnik Minangkabau AbstractPreeclampsia-eklampsia still being a disease of theory. One of abnormality accured in preeclampsia is endothelial disfunction that is caused by changes in lipid profile. The objective of this study was to find out the difference of lipid profile mean level in preeclampsia and normal pregnancy at Minangkabau Ethnic. This was an observational study with cross-sectional design at  dr. M.djamil Padang Hospital, dr Reksodiwiryo Hospital and UPTD regional health laboratory of West Sumatera. The subjects consist of two groups, choosen by consecutiteve sampling. Each group consist of 27 subjects. Lipid profile was examined by using independent calorimetric methode. The data analyzed statistically by independent t-test. The result of this study showed mean level of total cholesterol in preeclamsia and normal pregnancy were 270.19±68.955 mg/dL and 247.56±44.415 mg/dL with p-value 0.158. The mean levels of triglyceride in preeclampsia and normal pregnancy were 296.07±157.993 and 272.89±44.415 mg/dL with p-value 0.504. The mean level of HDL in preeclampsia and normal pregnancy were 51.93±19.882 mg/dL and 63.33 mg/dL p-value 0.012. The mean level of LDL in two groups were 159±52.038 mg/dL and 129.67±38.692 mg/dL with p-value 0.023 and the mean levels of LDL/HDL ratio were 3.86±3,09 mg/dLin  preeclampsia and 2,08±0,64 in normal pregnancy. It can be concluded that there is no significant difference in total cholesterol and triglyseride between preeclampsia and normal in HDL and LDL and there is significant difference in LDL/HDL ratio between preeclampsia and normal pregnancy at Minangkabau Ethnic.Keywords: preeclampsia, total cholesterol, triglyceride, HDL, LDL, Minangkabau Ethnic


e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Marianne C. Jacobus ◽  
Max F.J Mantik ◽  
Adrian . Umboh

Abstract: Haemoglobin is the main component of red blood cells that serves as a transporter of oxygen and carbon dioxide in the blood. The normal range of haemoglobin values can be used to determine the degree of anemia according to age and gender. Geographical condition such as altitude influences the haemoglobin value. This study aimed to obtain the difference of haemoglobin levels between teenagers with good nutrition status who live at the highland and those at the seaside. This was an observational analytical study with a cross sectional design. Samples were students with good nutrition status of SMPN 3 Tomohon (living at the highland) and those of SMP Kristen Nazaret Tuminting (living at the seaside). There were 60 students who met the inclusion criteria as follows: adolescent, good nutrition status, healthy, aged 13-15 years, lived at the highland or at the seaside ≥ 6 month, and willing to be performed blood examinations, and had been approved by their parents. The Mann-Whitney test for the difference between haemoglobin levels of the two groups showed a p value < 0,001. Conclusion: There was a very significant difference between haemoglobin levels of good nutrition teenagers who lived at the highland and at the seaside. Keywords: haemoglobin levels, good nutrition, teenagers, highland, seaside  Abstrak: Hemoglobin merupakan komponen utama sel darah merah dan berfungsi sebagai transporter oksigen dan karbon dioksida dalam darah. Batas normal nilai hemoglobin dapat digunakan untuk menetapkan derajat anemia, dengan distribusi usia dan jenis kelamin spesifik didasarkan pada sampel referensi sehat. Kondisi geografis, seperti ketinggian tempat dari permukaan laut menjadi faktor pertimbangan dalam distribusi nilai normal hemoglobin. Penelitian ini bertujuan untuk mendapatkan perbedaan kadar hemoglobin antara remaja gizi baik yang tinggal di pegunungan dengan yang tinggal di tepi pantai. Jenis penelitian ini analitik-observasional dengan desain potong lintang. Sampel penelitian yaitu remaja gizi baik yang tinggal di pegunungan yaitu siswa SMPN 3 Tomohon dan yang di tepi pantai yaitu siswa SMP Kristen Nazaret Tuminting. Subjek penelitian berjumlah 60 remaja yang memenuhi kriteria inklusi yaitu gizi baik, sehat, berumur 13-15 tahun, berdomisili di pegunungan atau tepi pantai ≥6 bulan, bersedia dilakukan pemeriksaan darah, dan telah disetujui oleh orang tua. Data yang diperoleh dianalisis menggunakan uji Mann-Whitney dengan bantuan program SPSS. Hasil uji Mann-Whitney mengenai perbedaan kadar hemoglobin antara kedua kelompok menunjukkan nila p <0,001. Simpulan: Terdapat perbedaan yang sangat bermakna kadar hemoglobin remaja gizi baik yang tinggal di pegunungan dengan di tepi pantai.Kata kunci: kadar hemoglobin, remaja gizi baik, pegunungan, tepi pantai


2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Dr. Syeda Razia Bukhari ◽  
Syeda Ishrat Fatima ◽  
Amenah Rashid ◽  
Farhana Saba

The aim of the research is to investigate that emotional intelligence and self-esteem in male and female school students. The present research design is research cross sectional design.  Sample contained 200 students (100 =male, 100= female)   (mean age = 14.16, SD = 0.740) all belonging to the upper, middle and lower Scio economic status. Whole sample was collected from different schools of Karachi, Pakistan with the help of convenient sampling technique. First, the confidentiality about the participants demographic information was assured after that about the purpose and procedure of research explained to participants. The participants who given consent of participation in research, the demographic form, Urdu version of Rosenberg Self-Esteem Scale (Rosenberg, 1965), and Trait Emotional Intelligence Questionnaire (TEIQue) (K.V. Petrides) were administered on them. Statistical Analysis (t-Test for independent) applied to assess the difference of emotional intelligence and self esteem among male and female.The results reveals there is significant difference among emotional intelligence of male and female school students (t (198) = 6.597, P< .05) and there is also significant difference in self esteem of male and female school students (t (198) = 2.837, P< .05).


2021 ◽  
Vol 21 (1) ◽  
pp. 59-65
Author(s):  
Alfun Dhiya An ◽  
Supriyatiningsih Supriyatiningsih

Endometrioma on the ovaries is a benign gynecological disorder that is often found in women of reproductive age. The approach was made to the malignant transformation through the study of cyclin-D1 expression. This research aim to analyze differences in the level of Cyclin-D1 expression in ovarian endometriosis and ovarian carcinoma associated with the pathogenesis of endometrioma and ovarian carcinoma. Analytical observational study with cross sectional approach to cyclin-D1 expression between endometrioma and ovarian carcinoma with good and bad differentiation. The research subjects were 20 cases of endometrioma, each of the 20 cases of ovarian carcinoma were well and poorly differentiated. Statistical analysis using the ANOVA test on the level of cyclin-D1 expression between groups. The mean cyclin-D1 expression in endometrioma was 67.25. The mean of well-differentiated ovarian carcinoma was 132.41. The mean of poorly differentiated ovarian carcinoma was 128.83. Anova test resulted in a significant difference between the expression of cyclin-D1 endometrioma and ovarian carcinoma with good and bad differences (p = 0.00 0.05). There is a significant difference between endometrioma and ovarian carcinoma with good and bad differentiation. Endometrioma cyclin-D1 expression was lower than ovarian carcinoma with good and bad differentiation.


e-GIGI ◽  
2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Lidia A. Kewo ◽  
Damajanty H.C. Pangemanan ◽  
Aurelia Supit

Abstract: To date, there are lots of documentations about the adverse effects of smoking on the oral cavity. Albeit, smoking is still considered as a casual thing in our community. Chemicals contained in the cigarette smoke can irritate the gums and soft tissues of the mouth, thus inhibiting wound healing after tooth extraction. This study was aimed to determine the difference in post-extraction dental wound healing between smokers and non-smokers. This was a comparative analytical study with a cross sectional design. Samples were obtained by using total sampling method. Subjects consisted of 16 smokers and 16 non-smokers that fulfilled the study eligibility criteria. Their oral cavities were examined to check the signs of inflammation (calor, dolor, rubor, tumor, and functio laesa). The results showed that there was a difference in post-extraction wound healing in inflammatory phase between smokers and non-smokers. As many as 9.4% of smoker patients and 34.4% of non-smoker patients recovered at 7 days post extraction. The Mann Whitney U test showed a p-value of 0.005. In conclusion, there was a significant difference in post-extraction wound healing between smokers and non-smokers.Keywords: smokers, non-smokers tooth extraction, wound healing Abstrak: Kebiasaan merokok bukan merupakan hal asing di masyarakat walaupun banyak dokumentasi mengenai akibat buruk dari merokok terhadap rongga mulut. Bahan kimia yang terdapat dalam asap rokok dapat mengiritasi gusi dan jaringan lunak mulut sehingga menghambat penyembuhan luka pasca ekstraksi gigi. Penelitian ini bertujuan untuk mengetahui perbedaan penyembuhan luka pasca ekstraksi gigi antara pasien perokok dengan bukan perokok. Jenis penelitian ialah analitik komparatif dengan desain potong lintang. Pengambilan sampel menggunakan total sampling yang memenuhi kriteria penelitian. Terdapat sebanyak 16 orang perokok dan 16 orang bukan perokok sebagai subyek penelitian. Pemeriksaan rongga mulut dilakukan untuk melihat tanda-tanda inflamasi (kalor, dolor, rubor, tumor, dan fungsio laesa). Hasil penelitian menunjukkan terdapat perbedaan penyembuhan luka 7 hari pasca ekstraksi gigi pada fase inflamasi antara pasien perokok dengan yang bukan perokok; sebanyak 9,4% pasien perokok dan 34,4% pasien bukan perokok yang sudah sembuh. Hasil uji Mann Whitney U mendapatkan nilai p=0,005. Simpulan penelitian ini ialah terdapat perbedaan bermakna dalam penyembuhan luka pasca ekstraksi gigi antara pasien perokok dengan yang bukan perokokKata kunci: perokok, bukan perokok, ekstraksi gigi, penyembuhan luka


2019 ◽  
Vol 7 (14) ◽  
pp. 2277-2281 ◽  
Author(s):  
Rinang Mariko ◽  
Eryati Darwin ◽  
Yanwirasti Yanwirasti ◽  
Sri Rezeki Hadinegoro

BACKGROUND: Dengue virus infection is an infectious disease caused by the dengue virus and transmitted by the Aedes aegypti mosquito. Dengue virus (DEN-V) consists of 4 serotypes, namely DEN-1, DEN-2, DEN-3, and DEN-4. The most feared result of DHF is death. Death in children is caused by hypovolemic shock due to plasma leakage from intravascular to extravascular space due to endothelial dysfunction. AIM: This study aims to analyse difference in sVE-Cadherin levels in Dengue Hemorrhagic Fever (DHF) with and without shock. MATERIAL AND METHODS: The method of taking samples is consecutive sampling, namely the research subjects obtained based on the order of entry in the hospital with a comparative cross-sectional design. From the results of the calculation using the sample formula, the sample size for each group is set at 32 people. So that the total sample size used for both groups is 64 people. The serum sVE-Cadherin levels using the ELISA method. The statistical test used is the independent t-test. The value of p < 0.05 was said to be statistically significant. RESULTS: The result showed that there was no difference in mean sVE-Cadherin levels between DHF patients with shock and without shock (p > 0.05). CONCLUSION: This study concluded that there was no difference in mean of sVE-Cadherin level in DHF patients with shock and without shock.


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