scholarly journals A Review on Synthesis of Silver Nanoparticles and their Biomedical Applications

2021 ◽  
Vol 11 (1) ◽  
pp. 3218-3231

The silver (Ag) metal is considered a very useful metal for treating consume wound diseases, open wounds, and cuts, respectively. Nowadays, nanotechnology has created a surprising effect by changing over metallic silver into silver nanoparticles (AgNPs) for better applications. However, according to advanced technology, the synthesis of nanoparticles occurs by using organic or biological techniques rather than physical and chemical techniques. Also, the synthesis of silver nanoparticles (AgNPs) using biological or organic sources is cost-effective and eco-friendly. Silver nanoparticles (AgNPs) are broadly used as antibacterial specialists, helping us cure novel diseases and questionable sicknesses. In biomedicine, silver nanoparticles have huge points of interest because of their physical and synthetic flexibility. The uses of silver nanoparticles (AgNPs) in nano-gels, nano-fluids, silver-based coating over food and medical devices are advancing. Still, there is a need to innovate a better version of silver nanoparticles for vigorous use in an eco-friendly way. So, this review describes the methods of synthesis, activities under various conditions, and different biomedical uses of silver nanoparticles (AgNPs) in detail.

2019 ◽  
Vol 25 (24) ◽  
pp. 2650-2660 ◽  
Author(s):  
Rajasree Shanmuganathan ◽  
Indira Karuppusamy ◽  
Muthupandian Saravanan ◽  
Harshiny Muthukumar ◽  
Kumar Ponnuchamy ◽  
...  

Generally, silver is considered as a noble metal used for treating burn wound infections, open wounds and cuts. However, the emerging nanotechnology has made a remarkable impact by converting metallic silver into silver nanoparticles (AgNPs) for better applications. The advancement in technology has improved the synthesis of NPs using biological method instead of physical and chemical methods. Nonetheless, synthesizing AgNPs using biological sources is ecofriendly and cost effective. Till date, AgNPs are widely used as antibacterial agents; therefore, a novel idea is needed for the successful use of AgNPs as therapeutic agents to uncertain diseases and infections. In biomedicine, AgNPs possess significant advantages due to their physical and chemical versatility. Indeed, the toxicity concerns regarding AgNPs have created the need for non-toxic and ecofriendly approaches to produce AgNPs. The applications of AgNPs in nanogels, nanosolutions, silver based dressings and coating over medical devices are under progress. Still, an improvised version of AgNPs for extended applications in an ecofriendly manner is the need of the hour. Therefore, the present review emphasizes the synthesis methods, modes of action under dissipative conditions and the various biomedical applications of AgNPs in detail.


2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Ram Prasad

Nanobiotechnology is emerging as a field of applied biological science and nanotechnology. Synthesis of nanoparticles is done by various physical and chemical methods but the biological methods are relatively simple, cost-effective, nontoxic, and environmentally friendly methods. The present review focuses on the synthesis of nanoparticles with special emphasis on the use of plants parts for the synthesis process, its applications, and future prospectus.


Author(s):  
M. Linga Rao ◽  
Bhumi G ◽  
Savithramma N

Silver nanoparticles (SNPs) exhibit tremendous applications in medicine as antimicrobial agent.  The use of different parts of plants for the synthesis of nanoparticles is considered as a green technology as it does not involve any harmful chemicals.  In the present study, we report a rapid biosynthesis of silver nanoparticles from aqueous leaf extract of medicinal plant Allamanda cathartica.  The active phytochemicals present in the plant were responsible for the quick reduction of silver ion to metallic silver nanoparticles. The reduced silver nanoparticles were characterized by using UV-Vis spectrophotometry, Scanning Electron Microscope (SEM), Energy Dispersive Analysis of X-ray (EDAX) and Atomic Force Microscopy (AFM).  The spherical shaped silver nanoparticles were observed and it was found to 19-40 nm range of size.  These phytosynthesized SNPs were tested for their antimicrobial activity and it analyzed by measuring the inhibitory zone. A. cathartica aqueous leaf extract of SNPs showed highest toxicity to Pseudomonas followed by Klebsiella, Bacillus and E. coli and lowest toxicity towards Proteus. In fungal species, highest inhibition zone was noted against Rhizopus followed by Curvularia, Aspergillus flavus and Aspergillus niger and minimum inhibition zone was observed against Fusarium species.  These results suggest a promising potential of Indian plant-based green chemistry for production of SNPs for biomedical and nanotechnology applications.


2021 ◽  
Author(s):  
Sunil T. Galatage ◽  
Aditya S. Hebalkar ◽  
Shradhey V. Dhobale ◽  
Omkar R. Mali ◽  
Pranav S. Kumbhar ◽  
...  

Nanotechnology is an expanding area of research where we use to deal with the materials in Nano-dimension. The conventional procedures for synthesizing metal nanoparticles need to sophisticated and costly instruments or high-priced chemicals. Moreover, the techniques may not be environmentally safe. Therefore “green” technologies for synthesis of nanoparticles are always preferred which is simple, convenient, eco-friendly and cost effective. Green synthesis of nanoparticle is a novel way to synthesis nanoparticles by using biological sources. It is gaining attention due to its cost effective, ecofriendly and large scale production possibilities. Silver nanoparticles (AgNPs) are one of the most vital and fascinating nanomaterials among several metallic nanoparticles that are involved in biomedical applications. It has vital importance in nanoscience and naomedicines to treat and prevent vital disease in human beings especially in cancer treatment. In current work we discussed different methods for synthesis of AgNPs like biological, chemical and physical along with its characterization. We have also discussed vital importance of AgNPs to cure life threatnign diseases like cancer along with antidiabetic, antifungal, antiviral and antimicrobial alog with its molecular mode of action etc. Finally we conclude by discussing future prospects and possible applications of silver nano particles.


2021 ◽  
Vol 09 ◽  
Author(s):  
Sarvat Zafar ◽  
Aiman Zafar ◽  
Fakhra Jabeen ◽  
Miad Ali Siddiq

: Nanotechnology studies the various phenomena of physio-chemical procedures and biological properties for the generation of nanosized particles, and their rising challenges in the various sectors, like medicine, engineering, agriculture, electronic, and environmental studies. The nanosized particles exhibit good anti-microbial, anti-inflammatory, cytotoxic, drug delivery, anti-parasitic, anti-coagulant and catalytic properties because of their unique dimensions with large surface area, chemical stability and higher binding density for the accumulation of various bio-constituents on their surfaces. Biological approaches for the synthesis of silver nanoparticles (AgNPs) have been reviewed because it is an easy and single-step protocol and a viable substitute for the synthetic chemical-based procedures. Physical and chemical approaches for the production of AgNPs are also mentioned herein. Biological synthesis has drawn attention because it is cost-effective, faster, non-pathogenic, environment-friendly, easy to scale-up for large-scale synthesis, and having no demand for usage of high pressure, energy, temperature, or noxious chemical ingredients, and safe for human therapeutic use. Therefore, the collaboration of nanomaterials with bio-green approaches could extend the utilization of biological and cytological properties compatible with AgNPs. In this perspective, there is an immediate need to develop ecofriendly and biocompatible techniques, which strengthen efficacy against microbes and minimize toxicity for human cells. The present study introduces the biological synthesis of silver nanoparticles, and their potential biomedical applications have also been reviewed.


2013 ◽  
Vol 756 ◽  
pp. 106-111 ◽  
Author(s):  
Selvaraj Arokiyaraj ◽  
Udaya Prakash Nyayiru Kannaian ◽  
Vijay Elakkya ◽  
T. Kamala ◽  
S. Bhuvaneswari ◽  
...  

The aim of the present study is to synthesize silver nanoparticles, using an aqueous floral extract of common Lotus, i.e Nelumbo nucifera. The synthesized nanoparticles were characterized using UV, TEM, EDX, AFM & XRD. The synthesized AgNPs were confirmed due to the colour change from colourless to reddish brown just after the addition of the aqueous floral extract of Nelumbo nucifera. The UV results of AgNPs showed the excitation of surface Plasmon resonance band at 427 nm. TEM results showed that the synthesized AgNPs were uniformed; monodispersed,spherical in shape and the particle size were found to be 77.81 ± 3.54 nm. EDX spectrum of AgNPs confirms strong signals from Ag (64%) and other elements such as C, O and Cl. The morphology of the synthesized AgNPs by AFM analysis resembled the TEM micrograph. The crystalline nature of the AgNPs was confirmed by XRD. The present study concludes that the aqueous floral extract of Nelumbo nucifera could be used as an effective reducing agent for the synthesis of AgNP. The green synthesis ofsilver nanoparticles is non-toxic and cost-effective and thus remains to be an alternative method to other physical and chemical reduction methods.


The usage of various plant extracts for green synthesis of magnetite nanoparticles, these plant extracts gaining importance day today when compared to the physical and chemical methods of synthesis due to its various advantages such as low cost, biocompatible, biodegradable, non-toxic. They also act as both reducing and capping agents during the synthesis of nanoparticles and this association achieved various pharmaceutical, and other biomedical applications. this study investigates the Plant mediated green synthesized Magnetite Nanoparticles (Fe3O4 NPs) for Antioxidant, antibacterial, Anticancer activities


2018 ◽  
Vol 6 (4) ◽  
pp. 294-301
Author(s):  
Dipesh Shahi ◽  
Elisha Bhattarai ◽  
Milan Poudel ◽  
Prarthana Pradhan ◽  
Raja Ram Pradhananga ◽  
...  

The green route of metal nanoparticles synthesis has received significant attention in recent years due to it's cost-effective, non-toxic and eco-friendly nature in comparison to other physical and chemical methods. This study reports on the synthesis of silver nanoparticles (Ag-NPs) from bio-reduction of 1mM aqueous silver nitrate (AgNO3) by extracts prepared from three different plants namely, Brassica oleracea L. var. italica Plenck (Broccoli), Capsicum annuum L. (Chili) and Parthenium hysterophorus L. (Carrot grass). The synthesized Ag-NPs were characterized using UV- visible spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). Ag-NPs synthesized showed the surface plasmon resonance with the appearance of absorption peaks around the range of 410-430 nm. The possible biomolecules involved in the reduction and the stabilization of synthesized Ag-NPs were found to be alcoholic, phenolic, amine and carbonyl groups. SEM study revealed that Ag-NPs were spherical in shape with varied size about 10-40 nm. Besides, the analysis of antioxidant and antibacterial activities of Ag-NPs was carried out. The Ag-NPs synthesized using B. oleracea extract showed the higher antioxidant activity than Ag-NPs synthesized from both C. annuum & P. hysterophorus extracts. Ag-NPs exhibited good antibacterial activity against both Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria. The higher antibacterial activity was shown by Ag-NPs synthesized from P. hysterophorus extract in comparison to Ag-NPs synthesized from both C. annuum & B. oleracea extracts. Hence, it can be concluded that Ag-NPs synthesized following the green route could be the source for potential antioxidant and antibacterial agents. Int. J. Appl. Sci. Biotechnol. Vol 6(4): 294-301


2020 ◽  
Vol 9 (1) ◽  
pp. 503-514 ◽  
Author(s):  
Khaleeq Uz-Zaman ◽  
Jehan Bakht ◽  
Bates Kudaibergenova Malikovna ◽  
Eman R. Elsharkawy ◽  
Anees Ahmed Khalil ◽  
...  

AbstractSynthesis of nanoparticles is a fast-growing area of interest in the current development in science and technology. Nanoparticles are also used in biomedical applications. Green synthesis of nanoparticles is an environmental friendly and cost-effective technique. Trillium govanianum Wall. Ex. Royle crude extract was used for the eco-friendly genesis of silver nanoparticles (AgNPs). Aromatic amines were the functional groups involved in the bio-fabrication and synthesis of the AgNPs. The production of AgNPs was established by the appearance of brown color. The manufactured AgNPs were characterized by UV-Vis spectrophotometer, X-ray diffractometer, and FTIR spectrophotometer. AgNPs were face-centered cubic in nature with an average size of 9.99 nm. The produced AgNPs (18 µL disc−1) showed substantial antibacterial (53.74, 52.75, 51.61, 43.00, 36.84, and 36.84%) and antifungal (54.05, 42.11, 41.10, 40.85, 30.55, and 29.73%) potential against the tested bacterial (X. campestris, P. aeruginosa, S. aureus, E. coli, B. subtilis, and K. pneumoniae) and fungal (A. alternaria, Paecilomyces, C. albicans, Curvularia, A. niger, and Rhizopus) strains, respectively.


2021 ◽  
Vol 37 (3) ◽  
pp. 667-672
Author(s):  
A. Arputharaj ◽  
P. Anbarasu

The nanotechnology has reached a greater extent of the research and now it is considered as the best source of alternative in the present world. Nowadays, the contaminants present in the water should be very difficult to remove and it leads to several health issues. It is the primary requisite to know about the different physico-chemical parameters to check the quality of water. Currently, the nanotechnology has been the emerging technology and the green synthesis is acclimating to eco-friendly, non-toxic and this method reduces the pollution. This biological approach is undertaken to diminish toxicity and to reduce pollution. In these current studies, the silver nanoparticles can be synthesized from chrysopogan zizanioides root extract. The synthesised silver nanoparticles were characterized by UV-Vis, TEM, physical and chemical parameters of water quality. The synthesised silver nanoparticles were used to reduce the chemical effluents. The outcome of the synthesis silver nanoparticles is using the vital route of wastewater treatment and also effectively reduces the water contaminations.


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