scholarly journals Serum zinc status of neonates with seizure

2016 ◽  
Vol 7 (2) ◽  
pp. 99
Author(s):  
Olia Sharmeen ◽  
Md. Abid Hossain Mollah ◽  
Md. Hasanur Rasbid ◽  
Shamshad B. Quaraishi
Keyword(s):  
Early Recognition ◽  
Venous Blood ◽  
Serum Zinc ◽  
Zinc Level ◽  
Neonatal Seizure ◽  
Zinc Status ◽  
Metabolic Derangement ◽  
Chemistry Division ◽  
Apparent Reasons

<p><strong>Background:</strong> Seizure is a common neurological disorder in neonatal age group!. Primary metabolic derangement is one of the important reason behind this convulsion during this period. Among primary metabolic derangement hypoglycemia, is most common followed by bypocalcaemia, hypomagnesaemia, low zinc status etc. As causes of many cases of convul­sion remain unknown in neonate. <strong>Objectives: </strong>To see the zinc status in the sera of neonate with convulsion. So that if needed early intervention can be taken up and thereby prevent complications. <strong>Method:</strong> A total of 50 neonates (1-28 days) who had convulsion with no apparent reasons of convulsion were enrolled as cases and 50 healthy age and sex matched neonates were enrolled as controls. After a quick clinical evaluation serum zinc status was estimated from venous blood by atomic absorption method in Chemistry Division, Atomic Energy Centre. Low zinc was considered if serum value was &lt;0.7mg/L. <strong>Results:</strong> Among a total of 50 cases 6% had low zinc value &amp; 2% of controls also had low zinc level. The mean serwu zinc level of cases and controls were 1.57±0.95 and 2.37±1.06 mmol/1 respectively (p&lt;0.01). <strong>Conclusion:</strong> From the study it is seen that low zinc value is an important cause of neonatal seizure due to primary metabolic abnormalities. So early recognition and treatment could save these babies from long term neurological sequelies.</p>

scholarly journals Hyponatremia And Disability, Prevalence And Prognosis In Babol Stroke Patients.

2017 ◽  
pp. 11
Author(s):  
Alijan Ahmadi Ahangar ◽  
Bahareh Bazuiar ◽  
Payam Saadat ◽  
Tahereh Haghshenas ◽  
Hamed Hosseinzadeh ◽  
...  
Keyword(s):  
Latex Particle ◽  
Venous Blood ◽  
Serum Zinc ◽  
Zinc Level ◽  
Stroke Severity ◽  
Stroke Patients ◽  
Normal Range ◽  
Cross Sectional ◽  
Disability Prevalence

Background: Stroke is the leading cause of serious long-term disability. In recent studies hyponatremia as a risk factor for stroke.Methods: This cross-sectional descriptive study was to evaluate serum zinc level in serum sodium over the first 24 hours after the onset of stroke. Different intensities were determined on Stroke Scale NIH (National Institute of Health) (mild 4-1) and (average moderate 15-5) and (moderate to severe 20-16) and (extreme severe 42- 21). Determination intensity of stroke after admission and discharge with Modified Rankin Scale and Barthel index. Blood serum concentrations of sodium 0.5 mL of venous blood were taken and sodium serum level was performed with Latex particle agglutination test in Ayatollah Rouhani Hospital. That normal range was defined 136-146 meq / LFindings: 125 patients were entered into this study; the prevalence of hyponatremia in female was 70% vs 60% in male. Of stroke patients included in this study 66% of them had hyponatremia and the frequency of hyponatremia in ischemic and hemorrhagic was 82% and 63%, respectively. Increase in hyponatremia with disability period of admission had statistically significant (10(12) mild vs 40(32) moderate, 32(25.6) severe, p=0.01) also with disability before discharge (24(19.2) mild, 26(20.8) moderate, 32(25.6) severe, p=0.03).Conclusions: Hyponatremia can effect on severity of the stroke and can be considered as a predictor of increased stroke severity and disability at admission and discharge.     

scholarly journals Correlation between Serum Zinc Level and Erythrocyte Superoxide Dismutase (SOD) Activity in Non-frail and Frail Geriatric Patients

2017 ◽  
Vol 1 (1) ◽  
pp. 34
Author(s):  
Rosnah Pinontoan ◽  
Savitri Sayogo ◽  
Arya Govinda Roosheroe
Keyword(s):  
Oxidative Stress ◽  
Superoxide Dismutase ◽  
Venous Blood ◽  
Serum Zinc ◽  
Zinc Level ◽  
Zn Deficiency ◽  
Serum Zinc Level ◽  
Physical Measurements ◽  
Significant Difference ◽  
The Mean

Introduction: Frailty syndrome (FS), as a health problem in elderly, can interfere with the quality of life. Many factors play roles in its occurrence, one of which is oxidative stress. Superoxide dismutase (SOD), in which one of its components is zinc (Zn), is one of the endogenous antioxidants that plays a role in preventing oxidative stress. This study was aimed to know the correlation between serum zinc level (sZn) and erythrocyte SOD (eSOD) activity in non-frail and frail geriatric patients.Methods: This was cross-sectional study with consecutive sampling method conducted in the Geriatric Clinic Cipto Mangunkusumo hospital, from August through September 2014, on 60 patients (30 patients for each group of non-frail and frail). Data were collected from interviews, physical measurements, and venous blood sampling.Results: Among 90% of the subjects had low Zn intake, at the same time, the mean of sZn was 8.41 ± 1.36mol/l and 93.3% of the subjects had experienced Zn deficiency. The mean of eSOD activity was 1526 ± 508U/gHb, and there was no significant difference between the groups. There were no significant correlation between sZn and eSOD activity both in the overall subject (r = -0.04; p = 0.076), as well as the non-frail group (r = -0.099; p=0.604) and frail  group (r = 0.01; p = 0.957).Conclusion: Serum zinc level did not have any significant correlation with the eSOD activity, neither on overall or both non-frail and frail groups.

scholarly journals Asupan seng dan status seng yang rendah sebagai faktor risiko kejadian infeksi filariasis (studi kasus di kota pekalongan)

2016 ◽  
Vol 4 (1) ◽  
pp. 67-70
Author(s):  
Dewi Nugraheni Restu Mastuti
Keyword(s):  
Immune Response ◽  
Risk Factor ◽  
Venous Blood ◽  
Serum Zinc ◽  
P Value ◽  
Zinc Status ◽  
Th2 Response ◽  
Zinc Intake ◽  
Control Approach ◽  
A Value

Background: Microfilariae infections in the human body does not always cause symptoms. filaria infected humans would induce a Th2 response by increasing the production of IL-4, IL-5, IL-13 and increased serum levels of IgE. Zinc deficiency is directly related to the regulation of immune response that is reduced due to decline in lymphopoesis as well as the effect on the immune response and the production of antibodies in people with normal nutritional status.Objective: This research is analytic survey with case control approach. Samples were selected with a total engineering sample of 42 people infected with filariasis of the samples taken by Comparing the number of 1 : 1. The subjects of the study were obtained when only 30 cases and 30 controls chosen. Zinc intake assessment is done by using a food frequency ( FFQ ) and food recall 3 x 24 hours later treated with Nutrisoft program. Assessment of serum zinc performed with venous blood sampling as much as 3 cc made 1 time. Statistical analysis was performed with chi square test.Results: Group infected and not infected with filariasis less zinc intake was 54.7 % and 45.3 % , zinc status is lacking in both infected and uninfected group was 50.0 % and 50.0 %. Thus intake of zinc and zinc status were less does not constitute a risk factor in the study group ( zinc intake : Value- p = 0.103 ; OR = 7.250 with a value 95 % CI = 0.815 to 64.45 and zinc status : p - value = 1.000 ; OR = 1,000 with a value 95 % CI = 0.131 to 7.605 ).Conclusion: The intake of zinc and low zinc status is not a risk factor incidence of filariasis infection in areas of research.

ACTIVITIES OF CARBONIC ANHYDRASE I (CA I) AND II (CA II) IN ERYTHROCYTES OF A PATIENT WITH CROHN’S DISEASE

1992 ◽  
Vol 02 (04) ◽  
pp. 505-510 ◽  
Author(s):  
TOSHIRO KUMAKAWA ◽  
TAKAHITO KONDO
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Specific Activity ◽  
Serum Zinc ◽  
Zinc Level ◽  
Sweat Glands ◽  
Acrodermatitis Enteropathica ◽  
Serum Zinc Level ◽  
Nutritional Disturbances

A 22-year-old male was hospitalized with mild fever, diarrhea, abdominal pain, and weight loss and was diagnosed as having Crohn’s disease. Total parenteral nutrition was administered to reduce bowel inflammation and correct nutritional disturbances. During long term intravenous hyperalimentation, the serum zinc level fell to 27 μg/dl and the patient developed acrodermatitis enteropathica and pancreatitis. Zinc supplementation resulted in the disappearance of these complications. Erythrocyte CA I-specific activity was 0.35 units/mg before zinc replacement, and recovered to 0.62 units/mg when the serum zinc level reached 124 μg/dl. CA I is present not only in erythrocytes but also in gastrointestinal epithelia, vascular endothelium, and sweat glands. To date there are no specific laboratory tests that reliably document tissue zinc deficiency. However, erythrocyte CA I activity may reflect the actual zinc status.

scholarly journals ETIOLOGICAL PROFILE OF NEONATAL SEIZURES WITH SPECIAL REFERENCE TO BIOCHEMICAL ABNORMALITIES

2019 ◽  
Vol 8 (6) ◽  
Author(s):  
Gurdeep Singh Dhanjal ◽  
Vikramjot Singh ◽  
Gurnoor Singh
Keyword(s):  
Seizure Activity ◽  
Early Recognition ◽  
Birth Asphyxia ◽  
Neurological Dysfunction ◽  
Neonatal Seizure ◽  
Neonatal Seizures ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Biochemical Abnormalities

Introduction: Neonatal seizure are the most frequent manifestation of neurological dysfunction in a neonate.  Detection of seizure and its etiology is important for guiding therapy. In the presence of biochemical abnormalities, it is difficult to control seizures and there is a risk of further brain damage. Early recognition and treatment of biochemical abnormalities are essential for optimal management and satisfactory long term outcome. The aim was to determine the etiology of neonatal seizures and to study the biochemical abnormalities. Material and Methods: The present study included 70 inborn neonates presenting with seizures admitted to the neonatal unit in MMIMSR, Mullana, Ambala, Haryana, India over a period of one and a half years. A detailed history was taken and clinical examination of the neonate was done. Etiological causes and various biochemical parameters were evaluated. Results:  Neonatal seizures occurred more commonly in males. The most common cause of neonatal seizures was birth asphyxia seen in 26 (37.1%) neonates followed by sepsis in 24 (34.3%) neonates. The Primary Biochemical abnormalities were seen in 12 (17.1%) neonates with seizures. Among these neonates, hypoglycemia was most commonly seen in 4 (33.3%) neonates followed by hypocalcemia seen in 3 (25%) neonates. Conclusion: Biochemical abnormalities are common in neonatal seizures and often go unrecognized. These abnormalities may significantly contribute to seizure activity and hence a biochemical workup is necessary for all cases of neonatal seizures.

scholarly journals Relationships between plasma zinc and ferritin with nutritional status in thalassemic children

2016 ◽  
Vol 46 (5) ◽  
pp. 220
Author(s):  
Luszy Arijanty ◽  
Sri Sudaryati Nasar ◽  
Bambang Madiyono ◽  
Djajadiman Gatot
Keyword(s):  
Nutritional Status ◽  
Negative Correlation ◽  
Ferritin Level ◽  
Venous Blood ◽  
Zinc Level ◽  
The Body ◽  
Zinc Status ◽  
Plasma Zinc ◽  
Cross Sectional ◽  
The Impact

Background Repeated blood transfusions in thalassemic chil-dren can lead to iron overload in the body. High ferritin level leadsto low plasma zinc status because of their competitive inhibition.Previous study found that there was a correlation between plasmazinc level and nutritional status.Objective To obtain plasma zinc level, to investigate the correla-tion between plasma zinc and ferritin, and the impact of plasmazinc on nutritional status in children with thallasemia.Methods A cross sectional study was conducted on 67 thalas-semic children. This study was performed at Thalassemia Center,Cipto Mangunkusumo Hospital, Jakarta, from 1 st until 31 st of March2005. The age of the patients ranged from 4 to 18 years, with fer-ritin levels more than 2000 ng/ml during the last 6 months or totaltransfusion more than 5 liters. The subjects were divided into 2groups, i.e. group 1 (4-10 years) and group 2 (>10-18 years). Di-etary intake was assessed by 3 day-dietary recall. The nutritionalstatus were judged by mid upper arm circumference (MUAC) forage and height for age (H/A). Venous blood was obtained to mea-sure plasma zinc and ferritin levels. Statistical analysis was doneby Student’s t-test (2-tailed) and linear regression analysis.Results We found that 42% subjects were well-nourished, 51%were undernourished, and 7% were severely malnourished. All sub-jects had low plasma zinc status 31.9 (SD 16.9) μg/dl. There was aweak negative correlation between plasma zinc and ferritin level (r= -0.282, P=0.021). Lower zinc intake was detected in 65 out of 67subjects.Conclusion All thalassemic children in our hospital had low plasmazinc level. There was a weak negative correlation between plasmazinc level and ferritin level. There was no significant correlationbetween plasma zinc status and nutritional status

Zinc Status of Filipinos by Serum Zinc Level: 7th National Nutrition Survey, Philippine 2008

2015 ◽  
Vol 5 (5) ◽  
pp. 565-566
Author(s):  
Mario Capanzana ◽  
Juanita Marcos ◽  
Leah Perlas ◽  
Phoebe Trio ◽  
Joselita Ulanday ◽  
...  
Keyword(s):  
Serum Zinc ◽  
Zinc Level ◽  
Zinc Status ◽  
Serum Zinc Level ◽  
Nutrition Survey ◽  
National Nutrition Survey

scholarly journals ASSESSMENT OF SERUM ZINC LEVEL IN CHILDHOOD EPILEPSY TREATED WITH LONG-TERM ANTI EPILEPTIC DRUG (AED

2020 ◽  
Vol 1 (1) ◽  
pp. 1-9
Author(s):  
Shamin-Ara Sarkar ◽  
Habibur Rahman ◽  
Israt Jahan ◽  
Sharmin Parveen ◽  
Md Ranzu Ahmed
Keyword(s):  
Antiepileptic Drugs ◽  
Serum Zinc ◽  
Zinc Level ◽  
Case Group ◽  
Childhood Epilepsy ◽  
Serum Zinc Level ◽  
Anti Epileptic Drug ◽  
Epileptic Child ◽  
Multiple Drugs

Almost 85% of epilepsy patients which is a common neurolotical disease lives in developing world. Mostly the disease start in childhoold in more than half o the cases. Long term use of antiepileptic drugs may alter serum zinc level.   The purpose of the present study was to assess the serum zinc level in childhood epilepsy treated with long-term Anti Epileptic Drug (AED). This cross-sectional study was carried out in the outdoor and indoor patient department of Pediatric neurology, BSMMU during the period from March 2013 to August 2013. Sample size was one hundred, among these fifty were case e.g. epileptic child who had received  anti epileptic drugs (Carbamazepine and/or Valproic acid) for more than three months and fifty werecontrol e.g. newly diagnosed epileptic child, who have not yet received antiepileptic drugs.  In this study, among100 epileptic child, mean serum zinc level in case group was 0.36(±0.20)(µg/ml)and incontrol group was 0.52(±0.26) (µg/ml),which was statistically significant (p<0.05). The use of one drug or multiple drugs in the treatment of epileptic patients has made the significant low serum zinc level.

Serum Zinc Level and Its Effect on Anthropometric Measurements in 7–11 Year-Old Children with Different Socioeconomic Backgrounds

2004 ◽  
Vol 74 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Tanzer ◽  
Yaylac_ ◽  
Üstdal ◽  
Yönem
Keyword(s):  
Primary Schools ◽  
Middle Eastern ◽  
Venous Blood ◽  
Serum Zinc ◽  
Atomic Absorption Spectrophotometry ◽  
Zinc Level ◽  
Z Score ◽  
School Students ◽  
Anthropometric Parameters ◽  
Serum Zn

This study was performed in order to determine the serum zinc (Zn) level of primary school students, to show the effect of socioeconomic status (SES) on the zinc level, and finally to show the effect of zinc deficiency on the anthropometric parameters. Ten different primary schools were included in the study according to SES. Four-mL venous blood samples were obtained under fasting conditions using disposable plastic syringes. Four hundred thirty-two randomly chosen students between 7 and 11 years of age were investigated. All the children were living in Sivas, a city located in the middle eastern part of Turkey. Serum Zn level was measured by atomic absorption spectrophotometry (Hitachi 2-800). The weight and height of each child was recorded. The SES of children included in this study was as follows: 43.1% low (n = 186), 34.3% middle (n = 148), and 22.7% high (n = 98). Mean serum Zn levels of low and middle SES subjects were 56.3 ± 17.50 mug/dL and 86.6 ± 26.8 mug/dL respectively, while in children with high SES the mean serum Zn was 110.7 ± 24.50 mug/dL. The difference between the groups was found to be statistically significant (F = 19.545, p < 0.05). When height-for-age z-scores were calculated according to SES, 105 of 186 children (56.4%) with low SES were found to have a z-score of –2 or lower and 14 of 147 children with middle SES had a z-score of –2 or lower. None of the children in the high SES group had a z-score of –2 or lower.

scholarly journals Evaluation of Serum Zinc Concentration in Vitiligo, A Case-Control Study

2020 ◽  
Author(s):  
Ahmed Abdul-Aziz Ahmed ◽  
Hayder Saad Ahmed ◽  
Ahmed Talib Abdulqader ◽  
Wisam Suhail Najem
Keyword(s):  
Rural Area ◽  
Case Control Study ◽  
Venous Blood ◽  
Serum Zinc ◽  
Zinc Level ◽  
Case Control ◽  
P Value ◽  
Serum Zinc Level ◽  
The Mean ◽  
Control Study

AbstractBackgroundVitiligo is an acquired autoimmune pigmentary disorder characterized by ivory white patches. Zinc is proposed to have an immune modulatory, antioxidant and antiapoptotic properties in vitiligo patients. The aim of this study is to evaluate serum zinc in vitiligo patients.Patients and methodsThis is case–control study conducted from December 2019 to May 2020. The study included 50 patient with vitiligo and 50 age- and sex-matched controls. A 2 ml venous blood sample was taken from patients and controls by zinc-free syringe and was measured by atomic absorption spectrophotometry.ResultsThe mean serum zinc level was 73.14±19.32 in patients group and 85.36±14.14 in controls group (p-value=0.005). It also was 77.65±22.07 and 82.84±14.32 in male patients and controls, respectively. In female patients, it was 70.82±17.65and in female controls was 82.88±13.79(p-value=0.02). Regarding the residence, the mean serum zinc level in patients group was 70.13±21.4 in urban and 76.39±17.73 in rural area. In controls group, mean serum zinc was 83.25±14.12 and 89.11±13.77 in urban and rural area, respectively (p-value=0.003). According to the clinical patterns of vitiligo, the mean serum zinc observed was 75.32±19.64 in vitiligo vulgaris, 70.45±21.23 in acrofacial vitiligo and 68.7±17.61 in segmental vitiligo (p-value=0.68).ConclusionSerum zinc level was significantly low in patients with vitiligo but not associated with the type of vitiligo or family history of autoimmune diseases. It was even lower when vitiligo is associated with nail changes than vitiligo without any nail abnormalities.

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