scholarly journals Evaluation of anti-coccidial drug sensitivity against experimental coccidiosis in broiler chicks

2016 ◽  
Vol 14 (1) ◽  
pp. 57-61 ◽  
Author(s):  
MA Lovelu ◽  
MH Talukder ◽  
MZ Alam ◽  
MA Karim

This study was undertaken to investigate the effect of sulphaclozine sodium and toltrazuril for the treatment of experimentally induced caecal coccidosis. Day-old chicks (n=96) reared in a coccidia free condition divided into six Groups (A, B, C, D, E and F) each having 4 subgroups of 4 chicks in each. At the age of 23 days the chicks were infected with 104 sporulated oocysts of E. tenella except control Group F and treated for 4 consecutive days from 3 days post infection. Then treatment was given in Group A (2 gm/L), B (3 gm/L) with sulphaclozine sodium and in Group C (1 ml/L), D (1.5 ml/L) with toltrazuril. Group E was maintained as infected, but untreated and Group F as negative control. After treatment Group A gained almost similar weight with Group F. A significantly higher (P<0.05) weight gain was recorded in Group A and B compared with Group C and D.The infected untreated chicks passed a large number of oocysts from day 5 till the end of the experiment. Chicks receiving sulphaclozine sodium (Groups A and B) had large oocysts count compared with the Groups C and D treated with toltrazuril but lower than the untreated chicks. At the end of experiment the lowest oocysts count was found in Group D (31.32 x 106) and highest in Group E (53.59 x106). Hence this study recommends to use sulphaclozine sodium and toltrazuril for chicken coccidiosis.J. Bangladesh Agril. Univ. 14(1): 57-61, June 2016

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Koernia H. Yonathan ◽  
Poppy M. Lintong ◽  
Meilany F. Durry

Abstract: Excessive exposure of sunlight may cause hyperpigmentation. Cocoa is a beneficial plant to the skin. This study was aimed to reveal the effect of cocoa bean extracts on the number of melanin pigments in rat skin after sun exposure. This was an experimental study using 25 Wistar rats (Rattus norvegicus) divided into one control group and four treatment groups. The treatment consisted of sunlight exposure for one hour/day and application of cocoa bean extract 1600 mg/day that varied among treatment groups. Group A was the negative control group (terminated at day 21). Group B, the treatment group 1, was exposed to sunlight for 30 days (terminated at day 31). Group C, the treatment group 2, was exposed to sunlight for 20 days (terminated at day 31). Group D, the treatment group 3, was divided into group D1 consisted of 2 rats and group D2 consisted of 3 rats. Group D1 was exposed to sunlight 30 minutes after the application of cocoa bean extract for 20 days (terminated at day 21). Group D2 was exposed to sunlight 30 minutes after the application of cocoa bean extract for 30 days (terminated at day 31). Group E was exposed to sunlight for 20 days and continued with the application of cocoa bean extract for the next 10 days (terminated at day 3). The results showed that sunlight exposure increased the number of melanin pigments in group B and C compared to group A. Group D showed fewer melanin pigments than group B and C. Group E showed fewer melanin pigments than group B, C, and D. Conclusion: Cocoa bean extract could reduce the number of skin melanin pigments in rats exposed to sunlight.Keywords: cocoa beans extract, sunlight, melanin pigment, skin Abstrak: Paparan sinar matahari yang berlebihan dapat menyebabkan hiperpigmentasi. Kakao merupakan tanaman yang berkhasiat untuk pemeliharaan kesehatan kulit. Penelitian ini bertujuan untuk mengetahui pengaruh pengolesan ekstrak biji kakao dan pemaparan sinar matahari terhadap jumlah pigmen melanin kulit tikus Wistar. Jenis penelitian ialah eksperimental dengan menggunakan 25 tikus Wistar (Rattus norvegicus) yang dibagi menjadi satu kelompok kontrol dan empat kelompok perlakuan. Perlakuan yang diberikan ialah paparan sinar matahari selama 1 jam/hari dan aplikasi ekstrak biji kakao dosis 1600 mg/hari yang bervariasi untuk masing-masing kelompok perlakuan. Kelompok A merupakan kontrol negatif (diterminasi hari ke-21). Kelompok B ialah kelompok perlakuan 1, diberi paparan sinar matahari selama 30 hari (diterminasi pada hari ke-31). Kelompok C ialah kelompok perlakuan 2, diberi paparan sinar matahari selama 20 hari (diterminasi hari ke-31). Kelompok D ialah kelompok perlakuan 3 yang dibagi menjadi kelompok D1 terdiri dari 2 tikus dan D2 dari 3 tikus. Kelompok D1 diberi paparan sinar matahari setelah diolesi ekstrak biji kakao 30 menit sebelumnya selama 20 hari (diterminasi hari ke-21). Kelompok D2 diberi paparan sinar matahari selama 1 jam setelah diolesi ekstrak biji kakao 30 menit sebelumnya selama 30 hari (diterminasi pada hari ke-31). Kelompok E ialah kelompok perlakuan 4 yang diberi paparan sinar matahari 20 hari dan dilanjutkan dengan pengolesan ekstrak biji kakao untuk 10 hari berikutnya (diterminasi hari ke-31). Hasil penelitian memperlihatkan bahwa kelompok B dan C menunjukkan peningkatan jumlah pigmen melanin dibandingkan kelompok A. Kelompok D menunjukkan jumlah pigmen melanin yang lebih sedikit dibandingkan kelompok B dan C. Kelompok E menunjukkan jumlah pigmen melanin yang lebih sedikit dibandingkan kelompok B, C, dan D. Simpulan: Ekstrak biji kakao dapat mengurangi jumlah pigmen melanin kulit tikus Wistar yang dipapar sinar matahari. Kata kunci: ekstrak biji kakao, sinar matahari, pigmen melanin kulit


Biomedika ◽  
2014 ◽  
Vol 6 (1) ◽  
Author(s):  
Adhimass Wicaksono ◽  
Retno Sintowati ◽  
Sa’idatul Fitriyah

The using of plant-based medicine is a popular approach to health care. A study presented by American Hearth Association showing that brown rice can lower cholesterol level in bood serum. To know the benefi ts of Angkak’s steeping water to decrease serum cholesterol levels in mice and determine the effects of Angkak’s steeping water to decrease serum cholesterol levels in rats compared with simvastatin. This study used an experimental research design, and using pre and post test control group design, performed in the laboratory of biomedical III FK UMS on November 1, 2012 to date of January 1, 2013. The purposive sampling technique, sampel determinaton using formula Federer by the number of sample of 30 male white rats wistar strain. After the data is collected, analyzed using the Shapiro-Wilk test, ANOVA, LSD, and the unpaired t test. The result of this study demnstrate hypothesis testing using ANOVA test with signifi cant level 95% of the negative control group, the treatment group a dose of 1, 2, and 3, it was found p<0,05 were signifi cantly different meaning. In the test dose of LSD between treatment groups 2 and 3 the value of p=0,839 (p>0,05) wich means no signifi cant difference. In the unpaired T test between the treatment group a dose of 1, 2, and 3 with positive control group were signifi cant difference. The unpaired T test between the treatment group a dose of 1, 2, and 3 with white rice also found signifi cant difference. Conclusion: Angkak’s steeping water can lower serum cholesterol levels of white rat as well as the water steepimg Angkak has the same effectiveness with simvastatin to decrease serum cholesterol levels of mice.Keyword: Cholesterol, Angkak


2014 ◽  
Vol 11 (1) ◽  
pp. 1-5 ◽  
Author(s):  
S Khatun ◽  
M Mostofa ◽  
F Alom ◽  
J Uddin ◽  
MN Alam ◽  
...  

The efficacy of tulsi (Ocimum sactum) and neem (Azadirachta indica) leaves extract as a growth promoter were studied in broiler. A total of 40 day-old broiler chicks were purchased from Kazi hatchery and after three days of acclimatization the chicks were randomly divided into four groups (n=10). No vaccination schedule was practiced and no antibiotic was added in ration of group A, B, C, and D respectively. Group A served control without any supplements while group B, C and D were supplemented with combination of tulsi and neem extract @ 1 ml, 2ml and 3 ml/liter of drinking water. Live body weight gain was recorded weekly up to 6th weeks and hematological studies were performed at 21st and 42nd day of experiments. At the end of 42nd day of experiment final body weight of group A, B, C and D were 1561± 12.10 g, 1698± 12.87 g, 1608± 12.04 g and 1763± 13.28 g, respectively. The birds of group D utilized their feed more efficiently among the treatment groups (p<0.05). The net body weight gain were, 1533± 11.98 g, 1443± 11.32 g and 1588± 12.10 g in treated groups compared to control group (1393± 11.07 g ) and total net profit per broiler was 19.08, 40.10, 20.68 and 45.07 Taka , respectively. Hematological parameterss (TEC, PCV, Hb and ESR) were not significantly changed among the treated and control group suggesting no side effects of herbal extracts in broiler. It can be concluded that tulsi and neem extract is economic and safe in broiler production.DOI: http://dx.doi.org/10.3329/bjvm.v11i1.17728 Bangl. J. Vet. Med. (2013). 11 (1): 1- 5


2020 ◽  
Vol 6 (2) ◽  
pp. 168-175
Author(s):  
Atikur Rahaman ◽  
Md Bazlar Rashid ◽  
Md Mahmudul Hasan ◽  
Rakibul Islam ◽  
Fahima Binthe Aziz ◽  
...  

This study was conducted under the Department of Physiology and Pharmacology to determine the effects of Neem and Nishyinda leaves supplementation on growth performance and GUT biosis in broilers. A total of 40 day old broiler chicks were divided into four groups A, B, C and D. Group A was considered as control, fed only with commercial broiler ration. Group B supplemented with formulation of 2 gm grinded Neem leaves, Group C with 2 gm grinded Nishyinda leaves and Group D with 1 gm grinded Neem leaves plus 1 gm grinded Nishyinda leaves per liter of water respectively. Observations were recorded for live body weight, weight gain, feed consumption, feed efficiency, hemato-biochemical parameters and GUT biosis specially the parasite of birds in six weeks. Body weights were increased significantly (p<0.05) in all treated groups in respect to the control and highest was recorded in combine Neem plus Nishyinda supplemented groups (Group D). No significant (p>0.05) differences were observed among the groups for PCV and TEC values. Hb content increased and ESR decreased significantly (p<0.05) with combine Neem plus Nishyinda supplemented group (Group D). The serum SGOT and SGPT levels were also decreased with the same kind of supplementation. In treatment group there was significantly decreased of parasitic eggs, but in case of control group no decrease of parasitic eggs. There was no significant pathological change in any internal organs of the broiler of treated groups. Best result was found in the group D. The present study reveals that combine supplementation of Neem plus Nishyinda gives better result over other groups in respect to body weight gain, feed conversion ratio, hemato-biochemical parameter and profitability without making any health hazard of the broilers. Asian J. Med. Biol. Res. June 2020, 6(2): 168-175


2021 ◽  
Author(s):  
Muhammad Asif ◽  
Zafar Hayat ◽  
Abdur Rahman ◽  
Muhammad Fiaz Qamar ◽  
Muawuz Ijaz ◽  
...  

Abstract The study was designed to investigate the effect of mannan-oligosaccharide (MOS) supplementation on intestinal histomorphology, immunity against Newcastle disease virus (NDV) and productive parameters of broilers. A total of 1800 day old broiler chicks of Cobb-500 strain were selected and randomly assorted into 6 treatment groups: T1 (basal diet without antibiotics as negative control); T2 (basal diet plus antibiotics as positive control group); T3 (basal diet plus 200g/ton MOS); T4 (basal diet plus 400g/ton MOS); T5 (basal diet plus 600g/ton MOS) and T6 (basal diet plus 800g/ton MOS). Each treatment was having 6 replicates and the feed intake, body weight gain and feed conversion ratio (FCR) were recorded on weekly basis. Results showed that, MOS supplemented birds have significantly higher feed intake, weight gain and FCR (P < 0.05). Similarly, supplementation of MOS showed positive effect on villus height and crypt depth both in jejunum and ilium. Goblet cell density was unaffected by MOS addition (P < 0.05). Furthermore, birds fed with diets containing MOS, exhibited better productive performance in comparison to positive and negative control groups. In conclusion, MOS can replace antibiotic growth promoters (AGPs) as non-microbial performance-enhancing feed advocates.


2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Anggun R.P. Layuck ◽  
Poppy M. Lintong ◽  
Lily L. Loho

Abstract: Over exposure of light can increase skin pigmentation. The aim of this study is to know the effect of lime and light exposure to the amount of melanin in mice’s skin. This is an experimental research and used mices as the subject research, which was randomly divided into 5 mice of control group and 15 mices of treatment group. Group A (K-) were given pellets for 20 days, Group B (K+) were given pellets and light exposure for 1 hour in 20 days, Group C were given pellets, smeared by lime on the back, then exposed to the light for 1 hour in 20 days, Group D were given pellets and exposed to light for 1 hour in 20 days then smeared by lime the next 10 days. The results showed that light exposure increases melanin pigment in group B compared to group A. For group C and group D, the amount of melanin pigment is less than group B. Conclusions: Lime can reduce the amount of melanin pigment in mice’s skin that had been exposed to the light.Keywords: melanin pigment, sunlight, limeAbstrak: Paparan berlebihan terhadap sinar matahari dapat meningkatkan pigmentasi kulit. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian jeruk nipis dan pemaparan sinar matahari terhadap jumlah pigmen melanin kulit mencit. Metode penelitian yang digunakan adalah metode eksperimental dengan subjek penelitian menggunakan mencit yang dibagi atas 5 ekor kontrol dan 15 ekor perlakuan. Kelompok A (K-) diberikan pelet selama 20 hari, Kelompok B (K+) diberikan pelet dan sinar matahari selama 1 jam dalam waktu 20 hari, kelompok C diberikan pelet, diolesi jeruk nipis di bagian punggung, lalu dipaparkan sinar matahari selama 1 jam dalam waktu 20 hari, kelompok D diberikan pelet, dipaparkan sinar matahari selama 1 jam dalam waktu 20 hari lalu diolesi jeruk nipis 10 hari berikutnya. Hasilnya : paparan sinar matahari menunjukkan peningkatan pigmen melanin pada kelompok B (K+) dibandingkan dengan kelompok A (K-). Sedangkan pada kelompok C dan kelompok D menunjukkan jumlah pigmen melanin yang lebih berkurang dibandingkan kelompok B. Simpulan: Pemberian jeruk nipis menurunkan jumlah pigmen melanin kulit mencit yang dipaparkan sinar matahari.Kata kunci : pigmen melanin, sinar matahari, air perasan jeruk nipis


2018 ◽  
Vol 6 (2) ◽  
pp. 272
Author(s):  
Niki Niki Rahmawati ◽  
Sugiyanta Sugiyanta ◽  
Elly Nurus Sakinah

  High dose of paracetamol is metabolized by cytochrome P-450 become free radical N-acetyl-p-benzoquinoneimine (NAPQI) but liver Glutathione (GSH) is not adequate to change it become nonreactive metabolite so that NAPQI bind to unsaturated fatty acid of cell membrane, causing lipid peroxidation and increase liver Malondialdehyde (MDA). 'A' apple vinegar contains anthocyanin with an antioxidant effect by electron donor to NAPQI and acetic acid to improve liver GSH level. The aim of research was to investigate the effect of 'A' apple vinegar on the rat liver MDA induced by toxic dose of paracetamol. Research groups consist of normal control (CMC Na 1% 1 ml for 14 days), negative control (CMC Na 1% 1ml for 14 days + paracetamol 291.6 mg/200gBW on the day 12nd,13rd,14th), and treatment group ('A' apple vinegar 0.4 ml/150gBW for 14 days + paracetamol 291.6 mg/200gBW on the day 12nd,13rd,14th). Liver MDA was measured on the day 15th with competitive ELISA. The average of normal control group was 21.58 ng/ml, negative control group was 70,71 ng/ml, treatment group was 37,67 ng/ml. One way ANOVA and Post hoc LSD test showed significantly differences between all groups (p<0,05). It can be concluded that 'A' apple vinegar had an effect on the liver MDA induced by toxic dose of paracetamol.   Keywords: Paracetamol, NAPQI, MDA, 'A' apple vinegar, antioxidant  


1970 ◽  
Vol 6 (1) ◽  
pp. 31-36 ◽  
Author(s):  
P Monoura ◽  
M Rahman ◽  
MFR Khan ◽  
MB Rahman ◽  
MM Rahman

The effect of vitamins, minerals and probiotics supplementation to the balanced ration of the broiler chicks on the immune response and growth performance after vaccination with BCRDV was evaluated. For this 50 broiler birds were divided into five equal groups such as A, B, C, D and E, and five types of separate treatments with normal poultry feed were provided to the indivisual experimental groups. All the birds were vaccinated with BCRDV primarily at 3 days of age and boostered at 17 days of age. The birds of group A, B, C and D were supplemented with only probiotics, mixture of probiotics and minerals, mixture of probiotics, minerals and vitamins, respectively. The birds of group E were kept as vaccinated control. Blood samples were collected at the age of 9, 12, 16, 23, 26 and 30 days sequencially. The serum antibody titres were measured by HI test and ELISA. The highest value of HI antibody titre was 384±242.65 (Mean ±SD) in group B at 23 days of age. The lowest value of HI at 23 days was 56±32.86 (Mean ±SD) obtained in group C. The ELISA antibody titre was also highest (4675.12±485.72) at 23 days in group B and obviously the lowest (2169.38±724.45) in control group E. In case of group C, the ELISA antibody titre was 3105.73±877.57 at 23 days but then the titre decreased gradually compared to control group. The highest body weight (1420±90.82) was recorded at 30 days of age in group D and the lowest value (1188±44.38) was in group B. Key words: Probiotics, BCRDV, broiler birds DOI = 10.3329/bjvm.v6i1.1336 Bangl. J. Vet. Med. (2008). 6 (1): 31-36


Author(s):  
P. M. Sonkusale ◽  
Pratik N. Inglepatil ◽  
Siddharth V. Jamadade

A total of 75 day old broiler chicks were divided into three equal groups. Group A served as negative control. Group B (positive control) and C (treatment group) were intoxicated with oral administration of CCl4 @ 1 ml/kg body weight after every 3rd day during 15-28 days of age. Group C was given AV/LCP/18 @ 0.10 ml / chick / day in drinking water during 29th-42nd day of age. At the end of experiment, significantly (P is less than 0.01) higher mean body weight and lower FCR was observed in treatment group C as compared to positive control group B. Similarly, significantly (P is less than 0.05) decreased levels of SGOT, SGPT, cholesterol, triglycerides, creatinine and higher mean values of serum protein profile along with mild degenerative changes in liver and kidney of broilers in group C were observed as compared to group B indicating therapeutic efficacy of AV/LCP/18 in ameliorating the toxic effects or FLKS induced by CCl4 in commercial broilers


2017 ◽  
Vol 3 (3) ◽  
pp. 317-322
Author(s):  
Md Shafiqul Islam Khan ◽  
Md Shoaib Prodhan ◽  
Md Shahidul Islam ◽  
Md Nazmul Hasan ◽  
Md Shajadul Islam

This experiment was conducted to evaluate the efficacy of garlic (Allium sativum) extracts supplementation in drinking water as a growth promoter of broiler chicken. A total of 60 one-day-old male Lohman meat broiler chicks were distributed over two groups of 30 chicks with three replicates of 10 birds. Group B was supplemented with garlic extract from water and Group A kept as a control. Weekly observations were recorded for live body weight gain up to 4th weeks and hematological tests were performed at 30th days. Live weight and weight gain of the treatment group were significantly (p<0.05) higher than that of the control group. Significant (p<0.05) higher values also observed in terms of weight of heart, liver, spleen, and pancreas for the treatment group. The value of TEC and PVC of treatment group showed significant (p<0.05) differences. The results suggest that better growth performance could be achieved in broilers with feed supplemented with garlic extract.Asian J. Med. Biol. Res. September 2017, 3(3): 317-322


Sign in / Sign up

Export Citation Format

Share Document