Eliminating Hepatitis B from Bangladesh by the Year 2030

2020 ◽  
Vol 38 (3) ◽  
pp. 145-149
Author(s):  
Md Golam Mustafa ◽  
Md Shahinul Alam ◽  
Md Golam Azam ◽  
Md Mahabubul Alam ◽  
Md Saiful Islam ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Health Workers ◽  
Health Sector ◽  
Public Health Problem ◽  
Integrated System ◽  
Hbv Infection ◽  
Diagnosis And Treatment ◽  
Major Public Health Problem ◽  
Medical Institutions ◽  
The Government

Worldwide, hepatitis B virus (HBV) infection is still a major public health problem. Bangladesh having a large burden of HBV infection, should be a major contributor towards it’s elimination by 2030. The country has been making progress in reducing incidence of HBV infection during the past decades. The progresses are mainly due to large vaccination coverage among children and large coverage of timely birthdose vaccine for prevention of mother-to-child transmission of HBV. However, Bangladesh still faces challenges in achieving target of reduction in mortality from HBV. On the basis of targets of the WHO’s Global health sector strategy on viral hepatitis 2016–2021, we highlight priorities for action towards HBV elimination. To attain the target of reduced mortality we propose that, the service coverage targets of diagnosis and treatment should be prioritized along with vaccination. Firstly, improvements are needed in the diagnostic and treatment abilities of medical institutions and health workers. Secondly, the government needs to reduce the costs of health care. Thirdly, better coordination is needed across existing national program and resources to establish an integrated system for prevention, screening, diagnosis and treatment of HBV infection. In this way, we can make progress towards achieving the target of eliminating HBV from Bangladesh by 2030 J Bangladesh Coll Phys Surg 2020; 38(3): 145-149

scholarly journals Pleural Effusion Related to Chronic Hepatitis B Virus Reactivation: A Rare Association

2021 ◽  
Author(s):  
Ana Oliveira ◽  
Diana Valadares ◽  
Filipe Nery
Keyword(s):  
Hepatitis B Virus ◽  
Pleural Effusion ◽  
Hepatitis B ◽  
Antiviral Treatment ◽  
Public Health Problem ◽  
Hbv Infection ◽  
Viral Reactivation ◽  
Major Public Health Problem ◽  
Chronic Hepatitis B Virus ◽  
B Virus

Despite worldwide vaccination campaigns, hepatitis B virus (HBV) infection remains a major public health problem. The natural history ranges from asymptomatic infection to severe liver injury or failure, chronic complications or reactivation episodes. The effects of HBV on the organism are immunomediated, possibly triggering extrahepatic manifestations. Since 1971, only a few cases of pleural effusion related to HBV infection have been described. We report HBV-associated pleural effusion occurring during a viral reactivation episode. Antiviral treatment directed towards pleural effusion related to HBV infection should be dictated by underlying liver disease severity and not pleural effusion severity.

scholarly journals Prevalence and risk factors of hepatitis B in Tunisia

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
A Lahchaichi ◽  
M Ben Hadj ◽  
H Bouguerra ◽  
K Talmoudi ◽  
A Bahrini ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis B ◽  
Protective Factor ◽  
Univariate Analysis ◽  
Public Health Problem ◽  
Hbv Infection ◽  
Reference Laboratory ◽  
Major Public Health Problem ◽  
Hbs Ag ◽  
Associated Risk Factors

Abstract Background Hepatitis B virus (HBV) infection is a major public health problem. Data related to epidemiology, distributions and outcomes of VHB infections in Tunisia remains scarce. This work aimed to study the prevalence of HBV infections and their distribution as well as the main risk factors associated to HBV infection. Methods Our study was a cross-sectional household- based study carried out among a representative sample of 22 275 from January 2014 to December 2015. Sampling was based on the National Census of 2014. For data collection, questionnaires were administrated by trained investigator and blood samples were sent to the Reference laboratory for analysis of HBV markers. Results Among 21720 surveyed subjects, 19663 subjects had a laboratory tests and the serological results reached to 19155. Overall prevalence of HBs Ag was 1.7% [1.6-1.9]. Prevalence of HBsAg was significantly higher in men (2.1% against 1.4%; p < 10-3), in age group more than 20 years (2.1% against 0.1% p ≪10-3) and in the Central region (2.3%; p < 10-3). Among the associated risk factors in univariate analysis were chronic dialysis, dental care, surgical intervention, hospitalization, traditional circumcision, scarification and multiple sexual partners. Multivariate analysis showed that male gender, age over 20 years, center and south regions, hospital follow-up of a chronic pathology and having a family member chronic carrier of HBs Ag were the associated risk factors of HBV infection and vaccination was the only protective factor. Conclusions Our study allowed to have a clear estimate of the national prevalence of HBsAg and to classify Tunisia as a country of low endemicity of Hepatitis B. This decline is mainly due to the introduction of vaccination since 1995 and the improvement of the health system. However, more efforts should be paid to reduce nosocomial transmission and traditional high-risk behaviors. Key messages Tunisia has become a country of low endemicity for hepatitis B. This was a result to the introduction of vaccination since 1995.

scholarly journals Knowledge of Healthcare Professionals Regarding Hepatitis B in Rania Hospitals

2020 ◽  
pp. 178-186
Author(s):  
Zhino Raouf Ali ◽  
Mohammed Rasol Ahmed ◽  
Khalid Muhamad Hamad ◽  
Zhiar Hussen Wsu
Keyword(s):  
Data Analysis ◽  
Hepatitis B ◽  
Health Care Professionals ◽  
Healthcare Professionals ◽  
Public Health Problem ◽  
Hbv Infection ◽  
P Value ◽  
Major Public Health Problem ◽  
Hbv Vaccine ◽  
Level Of Knowledge

Hepatitis B virus (HBV) infection is a major public health problem worldwide especially for healthcare professionals (HCPs). It is a potentially life-threatening condition because leads to liver infection, and liver cancer. There is a shortage of research on undergraduate students. The main aim of this study was conducted to assess the level of knowledge of health care professionals regarding HBV at Rania hospitals in the Kurdistan region of Iraq during the period of 20th October 2019 to 16th April 2020. Non- probability purposive sample of (303) HCPs; for data collection, the study instrument was constructed and designed through reading literature, books, and articles which included (42) items. Reliability of the instrument was determined through the use of stability reliability (test and retest) approach which was estimated as r = (0.83.)The data were collected through the use of the interview technique then organized and coded into computer files. Statistical approaches were uses for data analysis, which includes: descriptive and inferential statistics and chi-square, data analysis (SPSS version 25). The results indicated that the majority of the study samples were in the age group (≤ 30)) years and the female participants was more than male, three-quarters of the participants were married, most of them were graduated from institute nursing and less than half of HCPs had 6-10 years of employment, but the majority of the participants were not trained at all, and most of them had not immunized against HBV vaccine. Three-quarters of HCPs had moderate knowledge regarding HBV infection. Also, the current study demonstrated a significant association between the educational level and HCP's knowledge regarding HBV, at a P value less than 0.05. on site other hand, there was no significant association between HCP's age, gender, marital status, years of employment, and training course concerning hepatitis with the level of knowledge regarding HBV. The researchers recommended to the ministry of health and directorate of health in Rania city to complete vaccinate against HBV for all HCPs and participating their staff in healthy scientific issues and symposiums.

scholarly journals The Interactions Between HBV and the Innate Immunity of Hepatocytes

Viruses ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 285 ◽  
Author(s):  
Fayed Attia Koutb Megahed ◽  
Xiaoling Zhou ◽  
Pingnan Sun
Keyword(s):  
Innate Immunity ◽  
Hepatitis B ◽  
Current Knowledge ◽  
Hepatitis B Surface Antigen ◽  
Deep Understanding ◽  
Public Health Problem ◽  
Hbv Infection ◽  
Major Public Health Problem ◽  
Immune Recognition

Hepatitis B virus (HBV) infection affects ~350 million people and poses a major public health problem worldwide. HBV is a major cause of cirrhosis and hepatocellular carcinoma. Fewer than 5% of HBV-infected adults (but up to 90% of HBV-infected infants and children) develop chronic HBV infection as indicated by continued, detectable expression of hepatitis B surface antigen (HBsAg) for at least 6 months after the initial infection. Increasing evidence indicates that HBV interacts with innate immunity signaling pathways of hepatocytes to suppress innate immunity. However, it is still not clear how HBV avoids monitoring by the innate immunity of hepatocytes and whether the innate immunity of hepatocytes can be effective against HBV if re-triggered. Moreover, a deep understanding of virus–host interactions is important in developing new therapeutic strategies for the treatment of HBV infection. In this review, we summarize the current knowledge regarding how HBV represses innate immune recognition, as well as recent progress with respect to in vitro models for studying HBV infection and innate immunity.

scholarly journals Assessment of knowledge, attitude and practice of health care workers towards Hepatitis B in Kabul, Afghanistan

2020 ◽  
Author(s):  
Rohullah Roien ◽  
Sayed Hamid Mousavi ◽  
Mohammad Hossein Delshad ◽  
Fatemeh Pourhaji
Keyword(s):  
Health Care ◽  
Hepatitis B ◽  
Health Care Workers ◽  
Public Health Problem ◽  
Hbv Infection ◽  
Major Public Health Problem ◽  
Cross Sectional ◽  
Attitude And Practice ◽  
Care Workers ◽  
Knowledge Attitude And Practice

Abstract Background: Hepatitis B virus (HBV) infection is a major public health problem worldwide. Health care workers are at high risk of obtaining HBV infection due to direct interaction with HBV-infected blood and body fluids in their workplace.Objective: The purpose of this research was to assess KAP of Health care workers towards Hepatitis B infection in Kabul.Methods: this cross-sectional study was conducted between November, 2018 and January; 2019 among 502 health care workers using simple random sampling method. The tool for data collection was a self-administered structured questionnaire. The collected data were analyzed using SPSS 16.00.Results: The overall knowledge, attitude and practice score of HCWs were 86.58%, 34.73% and 61.22% respectively. Most of participants correctly identified HBV transmissions. Health care workers with higher education level, showed good knowledge than those with low educational level (p < 0.0001). The majority of the participants had a poor attitude towards HBV prevention (53.98%). only 77.45% of participants had been screened for HBV and 56.37% of participants had been vaccinated against HBV, only 5.17% had completed three doses of vaccine.Conclusion: The finding of our study shows that health care workers in Kabul, are at higher risk of acquiring HBV infection due to low vaccination coverage and poor preventive practice. We recommend that free and compulsory vaccination, awareness and encouraging programs should be provided for all health care workers in order to increase favorable attitude and effective preventive measures for HBV infections.

scholarly journals Hepatitis B infection in the general population of China: a systematic review and meta-analysis

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Huai Wang ◽  
Peixuan Men ◽  
Yufeng Xiao ◽  
Pei Gao ◽  
Min Lv ◽  
...  
Keyword(s):  
Systematic Review ◽  
General Population ◽  
Hepatitis B ◽  
Rural Areas ◽  
Urban Areas ◽  
Meta Analysis ◽  
Public Health Problem ◽  
Hbv Infection ◽  
Control Measures ◽  
Major Public Health Problem

Abstract Background Hepatitis B virus (HBV) infection is a major public health problem in China. Over a decade has passed since the last National Hepatitis Seroepidemiological Survey was conducted in 2006. The lack of updated data on hepatitis B in China makes assessing the current prevalence and burden of the disease inadequate. In response to the above situation, a systematic review and meta-analysis was conducted to provide a better understanding of hepatitis B epidemiology in the general population of China. Methods A systematic search was conducted in international databases (Medline through PubMed, EMBASE, Cochrane, Web of Science) and national databases (CBM, CNKI, WanFang Data) to retrieve primary studies published between January 1, 2013 and December 31, 2017. The pooled prevalence of HBV infection and 95% confidence intervals were calculated. Quality assessment, heterogeneity testing and publication bias assessment were also performed. Results Of the 27 studies included in the meta-analysis, the pooled estimated prevalence of HBV infection in the general population of China from 2013 to 2017 was 6.89% (95% CI:5.84–7.95%), which could be extrapolated to an estimated population of 84 million living with HBsAg in 2018. The prevalence of HBV infection in males was higher than that in females (5.88% vs 5.05%), and rural areas had a higher prevalence than urban areas (5.86% vs 3.29%). The highest prevalence of HBV infection was reported in Western provinces (8.92, 95% CI: 7.19–10.64%). In adults older than 20 years, the prevalence of HBV infection was approximately 7%, which was higher than that in children. Conclusion The prevalence of HBV infection in the general population of China was classified as higher intermediate prevalence (5–7.99%), of which more than 90% of the HBV infection population included adults older than 20 years. The blocking of mother-to-infant hepatitis B transmission and plans involving timely birth dose of hepatitis B vaccine within 24 h should be implemented. Additionally, improving the quality of life and survival rate of the infected population through antiviral therapy and high-risk adult vaccination will be the priority of our future work. Moreover, various control measures should be implemented in different provinces across China.

Knowledge, Awareness and Perception on Malaria in Tribal Regions of Vadodara District, Gujarat (India)

2019 ◽  
Vol 21 (3) ◽  
pp. 406-416
Author(s):  
Bindu Bhatt ◽  
Janak P. Joshi
Keyword(s):  
Malaria Control ◽  
Control Measure ◽  
Health Sector ◽  
Public Health Problem ◽  
Signs And Symptoms ◽  
Well Being ◽  
Clear Understanding ◽  
Major Public Health Problem ◽  
Health Seeking ◽  
Tropical Regions

Malaria affects health and general well-being of many people in the developing world. In India also, malaria is a major public health problem. It continues to be a leading cause of morbidity and mortality in many tropical regions of the world, despite global efforts to eradicate the disease. To achieve the targets of reducing malaria prevalence and preventing malaria epidemic, it is essential to have active community participation. Therefore, clear understanding of the Knowledge, Awareness and Perception (KAPs) of a particular community can help in framing the policy of prevention and promotion of any malaria control measure. In this context, the decision makers in the health sector are recognizing the importance of community’s KAPs on malaria and, thus, is gaining stimulus as one of the methods for malaria control. KAPs, however, play an important role in the improvement of health and health-seeking behaviour of a disease-burdened group. This study, therefore, investigates a local community’s KAPs on malaria in tribal areas of Vadodara District. The KAP investigates the community’s understanding of malaria transmission, their recognition of signs and symptoms, their treatment-seeking behaviours and community preventive measures and practices.

Knowledge, attitude and practice towards hepatitis B infection among high school students in Asante Mampong, Ghana

2021 ◽  
pp. 1-11
Author(s):  
Godfred Otchere ◽  
Emmanuel Dwomoh ◽  
Emmanuel Kumah ◽  
Samuel Egyakwa Ankomah ◽  
Adam Fusheini ◽  
...  
Keyword(s):  
High School Students ◽  
High Schools ◽  
Hepatitis B ◽  
Public Health Problem ◽  
Hbv Infection ◽  
Basic Knowledge ◽  
Response Options ◽  
Preventive Practices ◽  
Attitude And Practice ◽  
Knowledge Attitude And Practice

BACKGROUND: Hepatitis B virus (HBV) infection is a serious global public health problem, with significant morbidity and mortality from acute and chronic complications. Increasing awareness and improving knowledge of HBV helps reduce the risk of the disease. Although many studies have been conducted on HBV in Ghana, few have focused on examining knowledge, attitude and preventive practices among adolescents towards the disease. OBJECTIVE: The objective of this study was to assess HBV knowledge, attitude and practice (KAP) among adolescents in high schools in the Asante Mampong Municipality in the Ashanti Region of Ghana. METHODS: A descriptive cross-sectional study was conducted among 398 adolescents from six senior high schools within the Asante Mampong Municipality. Data was collected using a 30-item structured questionnaire. Each item had two response options: “Yes” and “No”. A scoring system was generated and respondents were given a score on each item answered. A positive response to an item was scored 1 point and a negative response was scored 0. Scores were then summed up and averaged to give the mean knowledge, attitude and practice scores. RESULTS: The majority of the respondents were male (60%), between 15 and 17 years (45%), Christian (93%) and in their first year of study. The adolescents had basic knowledge, positive attitude, and poor practices towards HBV. There was no significant relationship between the demographic variables of the respondents and KAP mean scores. CONCLUSION: There is the need to introduce health education and awareness programs in schools within the Asante Mampong Municipality to improve students’ level of knowledge of HBV. Countrywide studies examining KAP towards HBV infection among adolescents are also warranted.

scholarly journals The Role of The Community in Combating The Covid-19 Pandemic in Indonesia

2021 ◽  
Vol 1 (1) ◽  
pp. 159-168
Author(s):  
Djufri Nurachman ◽  
Goddess Purnamawati
Keyword(s):  
Health Education ◽  
Small Businesses ◽  
Teaching And Learning ◽  
Health Workers ◽  
Health Sector ◽  
Economic Downturn ◽  
The Government ◽  
Curriculum Policies ◽  
Global Threat

Corona Virus Diseases 19 (Covid-19) has become a global threat. The role of the community is very much needed to break the chain of transmission of Covid-19. This study aims to determine the role of the Indonesian people in overcoming the Covid-19 pandemic in general, health, education, and the economy. Research method: using SLR. Data is collected from Scopus and indexed journals through a science direct and Garuda-based data system. Data were analyzed using content analysis techniques. Research Results: Indonesian people have implemented health protocols in the form of using masks outside the home, complying with PSBB policies, washing hands regularly. In the health sector, supporting health workers by helping to raise funds for PPE, conducting regional quarantine. In supporting education policies during the Covid-19 period, the context of which is the government, teachers, and parents, have been with all their might and dedication to provide facilities for students in the form of data packages, relaxation of curriculum policies, elimination of National Examinations, the effectiveness of teaching and learning activities in Indonesia. during the pandemic. To respond to the economic downturn itself, the community supports the return of the Indonesian economy, such as opening small businesses online, supporting policies for providing assistance and relaxing MSME loans by submitting small businesses, supporting government policies on tax relaxation. while still paying taxes. Conclusion: In general, the Indonesian people have been quite disciplined in trying to prevent the spread of COVID-19, both in the fields of health, education, and the economy.

scholarly journals Simple and Feasible Detection of Hepatitis B Virus via Combination of Multienzyme Isothermal Rapid Amplification and Lateral Flow Dipstick Strip

2021 ◽  
Vol 8 ◽  
Author(s):  
Mao-Ling Sun ◽  
Hai-Yun Lai ◽  
Na-Yu Chong ◽  
Dong-Fan Liu ◽  
Zhen-Yi Zhang ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Public Health Problem ◽  
Lateral Flow ◽  
Detection Sensitivity ◽  
Clinical Samples ◽  
Major Public Health Problem ◽  
Lateral Flow Dipstick ◽  
B Virus ◽  
Rapid Amplification

Hepatitis B virus infection is not only a huge burden in the field of social health but also a major public health problem that affects the lives and health of the people. Simple, rapid, feasible detection of HBV is critical for its prevention and spread, especially in the developing countries with low-resource laboratories. To this end, we combined multienzyme isothermal rapid amplification (MIRA) and lateral flow dipstick (LFD) strip to detect HBV. A pair of primers targeting the conserved region of HBV genome was designed and used in MIRA-LFD assay. Our results found that the entire amplification of MIRA-LFD only takes 10 min at 37°C and the dilution of the amplification products was added in the LFD strip and observed by the naked eye after 10 min. The detection sensitivity of this method can reach 10 pg. The 45 clinical samples were detected by MIRA-LFD and real-time PCR. The accuracy rate of MIRA-LFD was 100%. Therefore, these characteristics of our newly developed MIRA-LFD assay make it particularly useful and suitable for detecting HBV in the resource-limited condition.

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