scholarly journals Clinical Profile and Underlying Cause of Acute Pancreatitis among a Group of Bangladeshi Patients

2020 ◽  
Vol 32 (1) ◽  
pp. 21-24
Author(s):  
ANM Saifullah ◽  
Madhu Sudan Saha ◽  
Bimal Chandra Shil ◽  
Ali Monsur Md Shariful Islam ◽  
Arifa Akhter ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Gall Stone ◽  
Clinical Profile ◽  
Medical Emergency ◽  
High Morbidity ◽  
Cross Sectional ◽  
Medical College ◽  
North East ◽  
Medicine Today

Introduction:Acute Pancreatitis is a medical emergency, which is one of the most common conditions for hospital admission. Very few studies have yet investigated in Bangladesh. Objective of this study was to define demographic characteristics, clinical profile & underlying etiologies. Materials and Methods: This hospital based cross sectional descriptive study was performed in Sir Salimullah Medical College Mitford Hospital, Dhaka & North East Medical College, Sylhet, Bangladesh from January 2015 to December 2017. One hundred and five consecutive patients of acute pancreatitis (AP) were enrolled for this study. Clinical features and investigations were systematically recorded. Diagnosis of acute pancreatitis was made by the presence of the two of the three following criteria: i. abdominal pain consistent with the disease ii. serum amylase and /or lipase greater than three times from the upper limit of normal, and/or iii. characteristic findings of abdominal imaging. Results: Total of 105 patients took part in the study, of them 65 were male. The mean age was 42.76 ±15.88. Abdominal pain & vomiting was the most common mode of presentation. Gall stone and hypertriglyceridaemia were responsible of 20% of acute pancreatitis. Ascariasis also causes acute pancreatitis in two patients. Conclusion: Acute pancreatitis is a condition associated with high morbidity and mortality. Ascariasis also causes acute pancreatitis in endemic area. Patients usually respond conservative treatment but endoscopic treatment is effective in few cases. Surgery is rarely required. Medicine Today 2020 Vol.32(1): 21-24

scholarly journals GENDER DIFFERENCES IN CHILDHOOD POISONING

2013 ◽  
Vol 03 (02) ◽  
pp. 069-072
Author(s):  
Pratik Vijay Tarvadi ◽  
Shankar M. Bakkannavar ◽  
Vikram Palimar ◽  
G. Pradeep Kumar ◽  
Mahabalesh Shetty ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Morbidity And Mortality ◽  
Medical Emergency ◽  
High Morbidity ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Childhood Poisoning ◽  
Males And Females ◽  
The Difference

Abstract Background: Accidental paediatric poisoning is a common medical emergency and also associated with a high morbidity and mortality in children. In developing countries like India, the poisoning emergencies are becoming a major cause of mortality in infants and toddlers. Among the various studies done on poisoning cases in our country, the study on poisoning is more or less only on adults and hence this study is taken up to understand the number of childhood poisoning cases (based on gender). Method: A ten year record based cross sectional study from January 1999 to December 2008 was conducted at the Department of Forensic Medicine & Toxicology, Kasturba Medical College, Manipal, to understand the magnitude of childhood poisoning cases among males and females at Kasturba Hospital, Manipal. Results: Male children were predominantly affected (male: female::1.32: 1). Most of the poisoning cases occurred at home in both the genders with boy to girl ratio based on percentage in indoor poisoning being 0.92:1 and boy to girl ratio based on percentage in outcome being 1.06:1. Conclusion: Our study examines the difference in place and outcome of poisoning among boys and girls to identify population at risk and give suggestions so as to reduce the morbidity and mortality.

scholarly journals Etiological Factors of Non Alcohol Non Gallstone Related Acute Pancreatitis: A Cross sectional hospital based study from Medical College and Hospital, Kolkata, West Bengal

2014 ◽  
Vol 4 (3) ◽  
pp. 351-362 ◽  
Author(s):  
Indraneel Banerjee ◽  
Indrajit Banerjee ◽  
K N Das ◽  
Brijesh Sathian ◽  
Bakthavatchalam Pugazhandhi ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Logistic Regression ◽  
West Bengal ◽  
Gall Stone ◽  
Specific Treatment ◽  
Sphincter Of Oddi ◽  
Gallstone Pancreatitis ◽  
Cross Sectional ◽  
Etiological Factors ◽  
Medical College

Background  Gall  stone  diseases and  alcohol  are  the  two  most  common causes  of  acute  pancreatitis. The  present  work  was undertaken  to  identify the  various etiological  factors  in  acute  pancreatitis  after  excluding  alcoholism  and  gall  stone  diseases. The etiology of an attack of non alcohol non gall stone acute pancreatitis is highly variable. The main objective was to identify the causing factor, because it can have an effect on the specific treatment of acute pancreatitis. . This is a rare cross- sectional study of its kind which is the first one to be reported from India. Materials and Methods A cross-sectional community based study was designed and conducted in Medical College and Hospital, Kolkata, West Bengal, India from July 2009 to June 2011. Z test and Chi square test were used to observe the variation between different variables and strength of the relationship with logistic regression.  Odd ratios were calculated and their 95% confidence intervals (95% CI). p < 0.05 was considered as statistically significant. Results CMV was the commonest etiology of non alcohol and non gallstone acute pancreatitis 26.7% followed by HEV 6.7% and Pancreas Divisum 6.7%%, SOD 3.3%, EBV 3.3%, Mumps 3.3%, Hepatitis 3.3%, Tumour 3.3%, Choledochal cyst 3.3%,Drugs 3.3% and Gallstone 3.3%. Logistic regression analysis finding indicates that acute pancreatitis was found more prevalent in < 40 yrs [OR 2.076,95%(CI 0.339, 12.716)] and among patients  having monthly income of <5000 rs/month yrs [OR 1.4,95%(CI 0.224, 8.768)] . According to the severity of CT grading, Patients had Grade D severity  [OR 2.667,95%(CI 0.158, 45.141)], Grade C[OR 1.333,95%(CI 0.104, 17.098)] and Grade E [OR 1.333,95%(CI 0.88, 20.108)]as compared to Grade B severity of CT.  Conclusion In the  study  an  etiological  factor  was  evident  among  almost 3/4th   of the patients  of  non-alcoholic  and  non-gallstone  pancreatitis. The most common etiological factors were CMV followed by HEV.  These  results  rather  suggests  that the most diligent  workup  including  a  biliary  microcrystal  analysis,  a  sphincter  of  Oddi  manometry  and  possible  gene  analysis  for  hereditary  disorders  may  further  reduce   the  apparently  idiopathic  group in  the  analysis  of  such  patients. DOI: http://dx.doi.org/10.3126/nje.v4i3.10663 Nepal Journal of Epidemiology 2014; 4(3): 351-62

scholarly journals Clinical profile of patients with acute pancreatitis in a tertiary care centre in Tripura: A retrospective study

2020 ◽  
Vol 11 (6) ◽  
pp. 96-100
Author(s):  
Surajit Kumar Das ◽  
Saswati Das
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Retrospective Study ◽  
Necrotizing Pancreatitis ◽  
Gall Stone ◽  
Clinical Profile ◽  
Morbidity And Mortality ◽  
Common Disease ◽  
Grading System ◽  
Etiological Factors

Background: Acute Pancreatitis is a common disease with wide clinical variation and its incidence is increasing. Acute pancreatitis is an inflammatory process leading to abdominal pain, progressive destruction of exocrine tissue and in some patients a loss of endocrine tissue as well, with multiple organ failure and high mortality. Severity of acute pancreatitis is linked to the presence of systemic organ dysfunction and/or necrotizing pancreatitis. Aims and Objective: The present study was aimed to study the clinical profile of acute pancreatitis, the etiology and complications of acute pancreatitis received treatment in the Department of Surgery, Tripura Medical College & Dr. BRAM Teaching Hospital, Agartala, Tripura. Materials and Methods: This was a hospital based retrospective study which was conducted from January 2019 to December 2019. All patients with a diagnosis of acute pancreatitis were included in this study in order to find out the clinical presentations from the available clinical, laboratory and radiological data. Result: Of the 100 patients in this study, 96 were male and 4 were female. Minimum age in our study was 10 years and maximum were 70 years. Maximum numbers of patients were below 45 years of age. Alcohol was identified as the most important etiological factor associated with acute pancreatitis. Among the known etiological factors 90% of the cases were related to alcoholism and 4% were due to gall stone disease. Abdominal pain and vomiting were the most common symptoms in our study. Epigastric tenderness was present in 90% of the cases and guarding/rigidity in 50% of cases. 14% patients showed jaundice as a sign of acute pancreatitis. There was no major difference between the CT grading system and clinical grading system. Most of the patients recovered with conservative treatment. Adverse outcome was noted in one patient with acute necrotizing pancreatitis. Conclusion: Acute pancreatitis is one of the leading causes of increase in morbidity and mortality to society. Clinical assessment along with radiological findings correlated well with the morbidity and mortality. Our study identifies alcoholism as one of the most important etiological factors.  

Clinical Profile and Outcomes in Patients with Acute Pancreatitis attending a Teaching Hospital at Gandaki Province, Nepal

2020 ◽  
Vol 16 (3) ◽  
Author(s):  
Subash Bhattarai ◽  
Merina Gyawali
Keyword(s):  
Acute Pancreatitis ◽  
Severe Acute Pancreatitis ◽  
Age Groups ◽  
Data Entry ◽  
Kidney Injury ◽  
Severity Index ◽  
Clinical Profile ◽  
Cross Sectional ◽  
Systemic Complications ◽  
Keywords Alcohol

Background: Acute pancreatitis (AP) is inflammatory process of pancreas presenting with acute abdominal pain.The majority of patients have mild disease. Some patients develop local and systemic complications with increased morbidity and mortality. This study was undertaken to describe the clinical profile and outcomes in patients with acute pancreatitis.   Methods:  A cross-sectional hospital based study comprising of 62 consecutive patients with acute pancreatitis were enrolled between Jan 2019 to August 2020. Clinical profile at admission, complications and clinical outcomes including mortality were studied. Patients were classified into mild, moderately severe and severe acute pancreatitis based on revised Atlanta classification and modified CT severity index.  Data entry was done in Statistical Packages for the Social Sciences version 20. Results: The mean age of study subjects was 44±10.87 years with 43 (56%) males and 19 (44%) females (M:F=2.1:1). The commonest etiology of pancreatitis was alcohol (53.2%) followed by biliary pancreatitis (37.1%)  The most common presentation was abdominal pain (100%). The most common complication was pancreatic necrosis (21%) followed by acute kidney injury (19.4%) and pleural effusion (17.3%). Majority( 72.6%) was mild and 17.7% had severe acute pancreatitis. Mortality was seen in 6.5% patients. Mortality was observed in patients with persistent complications, organ failure, low serum calcium and high modified CT severity index.   Conclusions: Alcohol and gallstones were the two main etiologies of acute pancreatitis and were common in males, and in middle age groups. Majority presented with mild severity. Mortality was observed in some patients with severe acute pancreatitis.   Keywords: alcohol; biliary; CT severity index; mortality; outcome; pancreatitis          

scholarly journals TO STUDY OF ASSOCIATION OF CLINICAL PROFILE WITH SERUM VITAMIN B12 AND FOLATE LEVEL IN CHILDREN WITH INFANTILE TREMOR SYNDROME

2021 ◽  
pp. 118-120
Author(s):  
Dinesh Kumar ◽  
Mahesh Kumar Gupta ◽  
Sunil Gothwal ◽  
Umesh Gurjar ◽  
Kailash Kumar Meena ◽  
...  
Keyword(s):  
Serum Vitamin ◽  
Psychomotor Retardation ◽  
Clinical Profile ◽  
Vitamin B ◽  
Folate Level ◽  
Cross Sectional ◽  
Medical College ◽  
Mother And Child Health ◽  
Mother And Child ◽  
And Child Health

Background-We planned the present study with objective of to find out correlation in vitamin B and folate levels with 12 clinical profile in children with ITS Methods- This Hospital based cross sectional observational study was conducted in, Sir Padampat Mother and Child Health Institute (SPMCHI),SMS Medical College,Jaipur. Results- Vitamin B and folate were reduced in children with generalized tremors, psychomotor retardation, delayed 12 milestones,presence of hepatomegaly and splenomegaly. Conclusion- All children with Infantile Tremor Syndrome should be screened for vitamin B and folate levels,high risk 12 children should be supplemented B and folic acid.

scholarly journals Magnitude of hypothyroidism among patients of cholelithiasis in a tertiary care centre in rural West Bengal: a prospective study

2021 ◽  
Vol 8 (11) ◽  
pp. 3375
Author(s):  
Jaganmoy Maji ◽  
Debjyoti Mandal
Keyword(s):  
Stone Formation ◽  
Tertiary Care ◽  
Gall Stone ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Medical College ◽  
Elder Patients ◽  
A Prospective Study

Background: Cholelithiasis is a common pathology of the gall bladder affecting about 10 to 15% of the adults in western countries and 2 to 29% in India. More than 80% of the patients with cholelithiasis are asymptomatic. Hypothyroidism may cause gall stone formation due to the hyperlipidemia, motility disorders affecting the bile duct and sphincter of Oddi.Methods: This was a descriptive cross-sectional study conducted at Department of Surgery, Bankura Sammilani Medical College and Hospital, Bankura from March 2019 to February 2020 for duration of one and half year. The sample size was 54 and consecutive non-probability sampling technique was used for the sampling. All the collected data were recorded in a pre-designed proforma and analyzed in MS excel.Results: Out of 54-patients with cholelithiasis, 28% patients were from the age group 45-54 years.40% patients were hypothyroid pre-dominantly females. Among 30-female patients 11 (26.82%) were hypothyroid and among 11-male patients 2 (15.38%) were hypothyroid. Hypothyroidism in male and female was statistically significant.Conclusions: This study was introduced to determine the relationship between hypothyroidism and cholelithiasis. It was concluded that hypothyroidism was more common in female, obese and elder patients. The gender distribution of the hypothyroidism in patients with cholelithiasis was statistically significant while all other variables were statistically not significant.  

scholarly journals Demographic profile of Acute Pancreatitis in Eastern India: A Single Centre Experience

2017 ◽  
Vol 8 (6) ◽  
pp. 24-29 ◽  
Author(s):  
Dibyendu Mukherjee ◽  
Shantanu Bhakta ◽  
Sandeep Lahiry ◽  
Rajasree Sinha
Keyword(s):  
Risk Factors ◽  
Acute Pancreatitis ◽  
Eastern India ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Medical College ◽  
Current Trends ◽  
Single Centre Experience ◽  
Cross Sectional Design ◽  
Gender Groups

Background: Little is known about the etiological risk factors of acute pancreatitis (AP) in Eastern India. Aims and Objective: The aim of this study is to assess current trends etiology of AP in Eastern India. Materials and Methods: A retrospective study with cross-sectional design was undertaken based on available medical records of patients admit between January 2014 and January 2017 with physician-assigned diagnoses of AP at KPC Medical College & Hospital, Kolkata (n = 234). Multivariate analyses were done to identify risk factors, and distribution was compared on the basis gender. Groups were selected on the basis of a working diagnosis. A stratified comparison was done in 3 commonest etiology groups identified: ‘alcohol’, ‘non-alcohol’ and ‘idiopathic’.Results: The commonest etiology was attributed to alcohol (29.4%), idiopathic cause (20.5%), and obstructive cause (14.5%). Prevalence of AP was higher with alcoholism in men (37% vs. 10.8%; p < 00.1), however, other causes like idiopathic cause (12.3% vs. 37.8%), duct obstruction (1.2% vs. 43.2%), obesity (6.1% vs. 24.3%), and hypertriglyceridemia (6.1% vs. 14.8%) were higher among females ( p < 0.001 for all comparisons). Compared to non-alcoholics, patients with idiopathic AP were more likely to be overweight ( p = 0.019) and have T2 DM ( p = 0.021). Moreover, impact assessment of T2 DM status further revealed that the risk of AP was even greater with obesity (Odds Ratio [OR] 1.37; 95% Confidence Interval [CI] 0.57 – 3.26; p = 0.047) and smoking (OR 1.72; 95% CI 1.0 – 2.97; p = 0.049). Eighteen cases (7.7%) of ‘severe’ AP were identified, mostly due to: trauma in 6 (2.5%), idiopathic in 6 (2.5%), gallstones in 4 (1.7%), and alcoholism in 2 (0.8%).Conclusion: Alcohol intake is the predominant etiological risk factor for acute pancreatitis in Eastern India. Gender and type 2 diabetes mellitus are important contributory determinants.Asian Journal of Medical Sciences Vol.8(6) 2017 24-29

Rotavirus Infection as Cause of Diarrhoea in Under-3- Years Children at Siddhartha Medical College, Vijayawada AP - A Hospital Based Cross Sectional Study

2021 ◽  
Vol 8 (30) ◽  
pp. 2731-2737
Author(s):  
Anil Kumar Paruchuri ◽  
Gowri Edagotti ◽  
Ramu Pedada ◽  
Haresh Morri
Keyword(s):  
Low Socioeconomic Status ◽  
Andhra Pradesh ◽  
Diarrhoeal Disease ◽  
Morbidity And Mortality ◽  
Child Rearing ◽  
High Morbidity ◽  
Cross Sectional ◽  
Rotavirus Infection ◽  
Medical College ◽  
Diarrhoeal Diseases

BACKGROUND Diarrhoeal diseases are significant public health problems that lead to morbidity and mortality of infants and children particularly in developing countries and developed countries too. Rotavirus is the most important virus responsible for severe diarrhoea among young children. India being a developing country, the incidence of diarrhoeal diseases is high. In this part of Andhra Pradesh, low socioeconomic status, bad feeding, and child-rearing practices along with malnutrition contribute to the high morbidity and mortality due to diarrhoeal disease caused by rotavirus infection. METHODS This cross-sectional hospital-based study was conducted from January 2018 to December 2018 in the Department of Paediatrics, Old Government Hospital, Siddhartha Medical College, Vijayawada, Andhra Pradesh after obtaining ethical clearance from Ethical and Research Committee of our institute. One hundred (100) children, fulfilling the selection criteria who were admitted in the three paediatric wards were the subjects of study. RESULTS In this present study, the incidence of rotavirus infection was high in children aged ≤ 12 months and least in children between the age group of 25 to 36 months. In our study, we found that majority of cases with rotavirus infection occurred from September to February (60 %). Reverse transcription – polymerase chain reaction (RT-PCR) test done for the 24-enzyme linked immuno sorbent assay (ELISA) test negative samples of this study group. Out of 24 ELISA negative samples, PCR detects 4 samples as positive as PCR test is more sensitive than ELISA. CONCLUSIONS Rotavirus diarrhoea is the most common cause of severe gastroenteritis (GE) in children below five years of age in most regions of India. In this part of Andhra Pradesh, the low socioeconomic status, bad feeding, and child-rearing practices along with malnutrition contribute to the high morbidity and mortality due to diarrhoeal disease caused by rotavirus infection. This data on rotavirus disease burden may likely support evidence-based decisions regarding any further intervention. KEYWORDS Rotavirus, Diarrhoea, Diarrhoeal Diseases, Gastroenteritis (GE) Children, RT-PCR

scholarly journals TRENDS OF POISONING AMONG CHILDREN AT KASTURBA HOSPITAL, MANIPAL

2013 ◽  
Vol 03 (02) ◽  
pp. 025-028
Author(s):  
Pratik Vijay Tarvadi ◽  
Shankar M. Bakkannavar ◽  
Manjunath S. ◽  
Vikram Palimar ◽  
G. Pradeep Kumar ◽  
...  
Keyword(s):  
Developing Countries ◽  
Retrospective Study ◽  
Forensic Medicine ◽  
Morbidity And Mortality ◽  
Medical Emergency ◽  
High Morbidity ◽  
Kasturba Medical College ◽  
Infants And Toddlers ◽  
Medical College ◽  
Childhood Poisoning

Abstract Background: Pediatric poisoning is a common medical emergency and also associated with a high morbidity and mortality in children. In developing countries like India, poisoning emergencies are becoming a major cause of mortality in infants and toddlers. Among the various studies conducted on poisoning in our country, the study on poisoning is predominantly on adults and hence this study is taken up to understand the incidence of childhood poisoning cases. Method: A ten year retrospective study from January 1999 to December 2008 was conducted at the Department of Forensic Medicine & Toxicology, Kasturba Medical College, Manipal, to comprehend the magnitude of childhood poisoning cases at Kasturba Hospital, Manipal. Results: Insecticide poisoning was the most predominant poisoning followed by venomous bites. Conclusion: Our study examines the most common poison involved and route of intake among children to identify specific ages at risk and give suggestions so as to reduce the morbidity and mortality.

scholarly journals Outcome of Patients Having Acute Myocardial Infarction with and without Streptokinase

2019 ◽  
Vol 31 (2) ◽  
pp. 68-71
Author(s):  
Faruque Uddin ◽  
AK Fazlul Hoque
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Hospital Mortality ◽  
Time Of Arrival ◽  
College Hospital ◽  
Medical College ◽  
North East ◽  
Acute Mi ◽  
Medicine Today ◽  
Mean Time

Introduction: Acute myocardial infarction is the leading cause of death. Streptokinase is the most commonly used thrombolytic agent. This study was conducted to compare in-hospital outcome of patients with acute myocardial infarction receiving streptokinase with those not receiving it. Materials & Methods: This descriptive observational study was conducted at Coronary Care Unit, North East Medical College Hospital from 1st July August 2016 to 30th June 2018. 340 patients having acute MI were in- cluded in the study. Two groups were formed: sk group receiving streptokinase and non-sk group not receiving. In-hospital mortality was the primary end point while mechanical and electrical complications were the secondary end points. Results: Among 340 patients, 255(75%) were males and 85(25%) females. Out of those 218 received strep-tokinase, while 122 did not. Mean age of sk group was 53.15±10.30 years and non-sk group 60.5±16 ears. Mean time of arrival to the hospital after symptom onset was 10.41±9.97 hours. SK group patients reached in 5.9±4.76 hours while non-sk group in 19.4±10.5 hours. In-hospital mortality in sk and non-sk group was 19(8.7%) and 25(20.5%) respectively, p=0.002. Complication rate was significantly higher in the non-sk group, 54.09% vs 34.86%, p=0.04. Conclusion: Patients of acute myocardial infarction receiving streptokinase have significantly lesser in-hospital mortality and complications as compared to patients not receiving it. Medicine Today 2019 Vol.31(2): 68-71

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