scholarly journals Hypoglycemic Effects of Spirulina (Spirulina Platensis) Leaves in Normal and Alloxan Diabetic Rat

2020 ◽  
Vol 7 (3) ◽  
pp. 475-479
Author(s):  
Mohammad Saiful Islam ◽  
Sujan Kumar Sarkar
Keyword(s):  
Body Weight ◽  
Blood Sugar Level ◽  
Leaf Extract ◽  
Experimental Period ◽  
Diabetic Control ◽  
Diabetic Rat ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Average Body ◽  
Average Body Weight

Hypoglycemic effects was observed with Spirulina (Spirulinaplatensis) when given as leaf extract in normal and alloxan diabetic rat. In this study 150 rats were included and divided into three groups of ten rats in each group. First group was normal control (A), Second group was diabetic control (B), third group was diabetic with Spirulina treated (C). The rats were treated with aqueous extract of Spirulina at a dose rate of 20 mg/kg body weight respectively for 3 weeks. During experimental period, day 0, day 7, day 14 and day 21 blood samples were collected from all groups and determined their blood sugar level using diabetic kit. The blood glucose levels were reduced from 165.5±10.65 mg/dL to 158.17±5.49 mg/dL in group C after 3 weeks treatment. On the other hand the average body weight were increased from 255.67±7.35 g to 286.17±8.56 g in group C after 3 weeks treatment. From the findings it is concluded that the Spirulina can be used as anti-diabetogenic agent in food. Res. Agric., Livest. Fish.7(3): 475-479,  December 2020

scholarly journals The Effects of Feed Color on Broiler Performance between Day 1 and 21

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1511
Author(s):  
Joseph P. Gulizia ◽  
Kevin M. Downs
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Treatment Effects ◽  
Body Weight Gain ◽  
Experimental Period ◽  
Feed Consumption ◽  
Feed Conversion ◽  
Broiler Performance ◽  
Average Body ◽  
Average Body Weight

Two trials were conducted to determine feed color effects on broiler performance. A completely randomized design was used. Trial 1 included four treatments: control (complete broiler starter diet), red, green, and blue; and Trial 2 included four treatments: control, orange, yellow, and purple. Each trial had 4 treatments with 4 replicates (60 birds/treatment) fed to 240 male Cobb 500 broilers during a 21 d grow out. Data were analyzed using the GLM procedure. In Trial 1, there were no treatment effects on average body weight, body weight gain, and feed consumption (p > 0.05). Adjusted feed conversion for control (1.23) was less than red (1.27; p = 0.001) and green (1.26; p = 0.009), with blue (1.25; p = 0.056) tending to be different during the experimental period. In Trial 2, there were no treatment effects on average body weight, feed consumption, and adjusted feed conversion during this study (p > 0.05). Body weight gain between d 1 to 14 for purple (490.78 g/bird) was more than orange (467 g/bird; p = 0.013) and yellow (461 g/bird; p= 0.004), with control (474 g/bird; p = 0.052) tending to be different. Results indicate that these feed colors had some, albeit limited, influence on broiler performance parameters.

scholarly journals Quantitative characteristics of the carcasses of Moxotó and Canindé goats fed diets with two different energy levels

2010 ◽  
Vol 39 (7) ◽  
pp. 1565-1570 ◽  
Author(s):  
Ana Cristina Chacon Lisboa ◽  
Dermeval Araújo Furtado ◽  
Ariosvaldo Nunes de Medeiros ◽  
Roberto Germano Costa ◽  
Rita de Cássia do Egypto Queiroga ◽  
...  
Keyword(s):  
Body Weight ◽  
Energy Level ◽  
Energy Levels ◽  
Experimental Period ◽  
Carcass Yield ◽  
Final Weight ◽  
Quantitative Characteristics ◽  
Energetic Level ◽  
Average Body ◽  
Average Body Weight

The objective of this work was to evaluate the quantitative characteristics of carcasses of Moxotó and Canindé goats finished in feedlots and fed diets of two levels of energy. It was used 40 castrated young goats, 20 from Moxotó breed and 20 from Canindé breed, each one with an average body weight of 15.2 kg. The animals were fed with diets containing 2.20 and 2.71 (Mcal/kg DM). The experimental period lasted 86 days. There was no difference among the barometric measures of Moxotó and Canindé kids. Canindé goats showed higher final weight, higher weight after fasting and higher hot and cold carcass weights when compared to the Moxotó animals. Animals that consumed diets with higher energy level had higher final weight and conformation as well as higher carcass yield. Considering the percentage values of the commercial meat cuts, no difference among treatments was observed. The diet was the factor that most influenced the non-constituent components of the carcass of Moxotó and Canindé goats. In general, animals belonging to the Canindé breed presented higher quantitative characteristics than the Moxotó breed. Supply of diets with higher energetic level (2.71 Mcal/kg DM) for goats from Moxotó and Canindé breeds, in feedlots, favors the production of carcass with higher yields and heavier commercial meat cuts.

scholarly journals Distiller’s dried grains with solubles (Zea mays L.) in feeding sheep on nitrogen balance

2017 ◽  
Vol 38 (6) ◽  
pp. 3807
Author(s):  
Luiz Juliano Valério Geron ◽  
Jocilaine Garcia ◽  
Sílvia Cristina de Aguiar ◽  
Kallynka Samara Martins Coelho ◽  
Ilda De Souza Santos ◽  
...  
Keyword(s):  
Zea Mays ◽  
Body Weight ◽  
Regression Analysis ◽  
Experimental Design ◽  
Nitrogen Balance ◽  
Zea Mays L ◽  
Latin Square ◽  
Experimental Period ◽  
Average Body ◽  
Average Body Weight

The objective of this study was to evaluate the effects of diets supplemented with 0.0, 8.0, 16.0, and 24.0% distiller’s dried grain solubles (DDGS) on nitrogen (N) intake, fecal and urinary N excretion, and N absorption and retention (N balance, NB) by feeding sheep. Four sheep of unidentified race were used, with an average body weight of 23.5 ± 1.5 kg, and housed in metabolism cages. We used a 4 × 4 Latin square design for the experimental design, and each experimental period lasted for 20 days. Data on N intake (NI), fecal N, urinary N, absorbed N, and NB were expressed in g day-1; percentage of NI and grams per kilogram of metabolic weight g (kg0.75)-1 were subjected to analysis of variance (ANOVA) and regression analysis at 5% probability. Inclusion of the different concentrations of DDGS in sheep diets had no effect on NI (mean of 15.11 g animal-1 day-1), nor on fecal and urinary N excretion (mean of 5.16 and 0.16 g animal-1 day-1, respectively). Moreover, DDGS supplementation did not alter NB or N absorption (mean of 9.79 and 9.95 g animal-1 day-1, respectively). Thus, it can be concluded that inclusion of up to 24% of DDGS in feed does not affect NI, fecal and urinary N excretion, and NB in sheep.

scholarly journals Antidiabetic potential of the leaf extract of Centella asiatica in alloxaninduced diabetic rats

2016 ◽  
Vol 4 (1) ◽  
pp. 51-59 ◽  
Author(s):  
Talha Bin Emran ◽  
Mycal Dutta ◽  
Mir Muhammad Nasir Uddin ◽  
Aninda Kumar Nath ◽  
Md Zia Uddin
Keyword(s):  
Body Weight ◽  
Leaf Extract ◽  
Total Cholesterol Level ◽  
Serum Insulin ◽  
Fasting Blood Glucose ◽  
Centella Asiatica ◽  
Liver Glycogen ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Diabetic Rat

The study was designed to evaluate the glucose and cholesterol lowering effect of the aqueous extract of Centella asiatica leaf using the alloxan-induced diabetic rats and compared the activity with diabetic control and antidiabetic drug (Glibenclamide). Leaf extract (50 mg/kg) of C. asiatica and Glibenclamide were administered to normal and experimental diabetic rats for the duration of 10 days. In the alloxan-induced diabetic rat model, C. asiatica extract (50 mg/kg) significantly (p < 0.05) lowered the fasting blood glucose level as well as the total cholesterol level. Serum insulin levels were not stimulated in the animals treated with the extract. In addition, changes in body weight, serum lipid profiles and liver glycogen levels assessed in the extract treated diabetic rats were compared with diabetic control and normal animals. Significant results (p < 0.05) were observed in the estimated parameters. Surprisingly, body weight was increased significantly (p < 0.05) in the C. asiatica treated diabetic group. Phytochemical screening showed the presence of alkaloids, flavonoids, glycosides, steroids and tannins in significant amountsJahangirnagar University J. Biol. Sci. 4(1): 51-59, 2015 (June)

scholarly journals Antidiabetic activity of curry leaves Murraya koenigii on glucose level, kidney and islets of langerhans in streptozotocin induced diabetes in rats

2016 ◽  
Vol 15 (1) ◽  
Author(s):  
Imad M. Al-Ani ◽  
Rahajoe I. Santosa ◽  
Muhammad H. Yankuzo
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Aqueous Extract ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Murraya Koenigii ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Curry Leaves ◽  
Aqueous Leaf Extract

Introduction: This study examined the antihyperglycemic effect of curry leaves, Murraya koenigii “MK” aqueous extract, and to examine its possible protective effects on the Islets of Langerhans and kidneys in streptozotocin (STZ) induced diabetic rats.  Methods: Thirty healthy adult male Sprague Dawley rats were randomized into five groups (n=6); normal control, normal treated with “MK” control, diabetic control (non-treated with “MK”), diabetic treated with 200mg/kg MK aqueous leaf extract and diabetic treated with 400mg/kg MK aqueous leaf extract. Blood glucose levels and body weight were monitored. The animals were sacrificed on the 30th day; the kidney and pancreatic tissues were processed for histological studies. Results: The diabetic control group significantly (p<0.001) showed considerable loss of body weight and increase in blood glucose levels and degeneration of the glomeruli and renal convoluted tubules and atrophied islets with disintegration of β-cells. Treatment of diabetic rats with aqueous extract showed significant (p<0.001) improvement in blood glucose levels and body weight gain.  The MK extract also caused an improvement in tissue injury induced by STZ injection in the kidney and endocrine pancreas.  Conclusions: These findings highlighted the beneficial effects of MK aqueous extract against cellular oxidative damage in STZ-induced diabetic rats.

scholarly journals Evaluation of antihyperglycemic activities of Bangladeshi medicinal plant Cinnamomum tamala Leaf extracts in alloxan treated Albino Rats

2017 ◽  
Vol 7 (1) ◽  
pp. 11
Author(s):  
Abu Zaffar Shibly ◽  
Laila Arjumand Suborna ◽  
Juthi Adhikari ◽  
Md. Shariful Islam
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Medicinal Plant ◽  
Type Ii Diabetes Mellitus ◽  
Diabetic Control ◽  
Antidiabetic Activity ◽  
Albino Rats ◽  
Leaf Extracts ◽  
Glucose Levels ◽  
Blood Glucose Levels

Background: Diabetic mellitus is a multifactorial disorder associated with its devastating consequences has assumed epidemic proportion in Bangladesh.Methods: The study evaluates the anti-hyperglycemic activity of the aqueous extracts of C. tamala (CTLEt) leaves in blood glucose of albino rats. Type II diabetes mellitus was induced by injecting alloxan at the concentration of 100mg/kg body weight in male albino rats. The diabetic rats were administered orally with aqueous CTLEt at the amount of 1.0ml, 1.5ml and 2.0ml with lab diet and glibenclamide (5mg/kg of body weight). Then blood glucose levels were estimated in all groups after 2 hours, 4 hours, 6 hours, 12 hours and 18 hours of the treatment with CTLEt and a known antidiabetic drug glibenclamide.Results: A comparison was made between the action of CTLEt and glibenclamide. Blood glucose levels of the CTLEt on 18th hours of the study were 8.6 to 5.1mmol/L (1ml CTLEt with lab diet), 10.4 to 4.9mmol/L (1.5ml CTLEt with lab diet), 14.7 to 4.3mmol/L (2.0ml CTLEt with lab diet) in comparison of diabetic control (9.5 to 8.5, 8.7 to 7.8, 7.7 to 7.1mmol/L) and glibenclamide (13.9 to 6.5, 16.3 to 6.1, 9.5 to 5.1mmol/L). Among the sample level, the 2.0ml CTLEt showed a higher efficiency of hypoglycemic effect on alloxan induced diabetic rats.Conclusions: Till date, there is no specific experimental work in Bangladesh about the evolution of antidiabetic activity of C. tamala plant in animal model. Further studies should be undertaken to find out the molecular mechanism of the leaf powder of C. tamala medicinal plant.

scholarly journals Uji Efek Antidiabetik Ekstrak Daun Trembesi (Albizia saman (Jacq.) Merr) Terhadap Mencit (Mus musculus L)

WARTA FARMASI ◽  
2019 ◽  
Vol 8 (2) ◽  
pp. 43-52
Author(s):  
Muhammad Azdar Setiawan ◽  
Muhammad Syaiful Saehu ◽  
Kartini Kartini
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Mus Musculus ◽  
Leaf Extract ◽  
Positive Control ◽  
Negative Control ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Reduce Blood Glucose ◽  
Albizia Saman

ABSTRAK Daun trembesi (Albizia saman (Jacq.) Merr) adalah salah satu tanaman berkhasiat menurunkan kadar glukosa darah dimana kandungan kimianya berpotensi menurunkan kadar glukosa darah antara lain flavonoid yang bekerja dengan cara menstimulasi sel- sel beta dari pulau langerhans, sehingga sekresi insulin ditingkatkan.Penelitian ini bertujuan untuk mengetahui efek antidiabetes ekstrak daun trembesi (Albizia saman (Jacq.) Merr) pada mencit (Mus musculus). Metode Penelitian ini merupakan penelitian Eksperimen dimana sebanyak 20 ekor mencit dibuat diabetes dengan menggunakan Streptozotosin 150 mg/kgBB secara Intraperitonial. Kemudian dibagi menjadi 5 kelompok perlakuan, yaitu: Ekstrak dosis 25 mg/kgBB, 50 mg/kgBB, 100  mg/kgBB, sebagai kontrol positif Glibenclamid 5 mg dan kontrol negatif suspensi Na.CMC 0,5%. Data yang diperoleh dianalisis dengan uji ANOVA. Hasil analisa statistik menunjukan pada konsentrasi ekstrak 100 mg/kgBB memberikan efek yang optimum dengan perlakuan kontrol positif Glibenklamid.  Kata Kunci  : Ekstrak Daun Trembesi, Antidiabetik.  ABSTRACT Trembesi leaf (Albizia saman (Jacq.) Merr) is one of the efficacious plants to reduce blood glucose levels where the chemical content has the potential to reduce blood glucose levels, among others, flavonoids that work by stimulating beta cells of the island langerhans, so that insulin secretion is increased. It aims to determine the antidiabetic effect of trembesi leaf extract (Albizia saman (Jacq.) Merr) in mice (Mus musculus). This research method is an experimental study in which as many as 20 mice were made diabetic using Streptozotosin 150 mg / kgBW intraperitonially. Then divided into 5 treatment groups, namely: Extract dose 25 mg / kg body weight, 50 mg / kg body weight, 100 mg / kg body weight, as positive control Glibenclamid 5 mg and negative control suspension Na.CMC 0.5%. The data obtained were analyzed by ANOVA test. The results of statistical analysis showed that the extract concentration of 100 mg / kgBB gave the optimum effect with the positive control of Glibenclamide. Keywords: Trembesi Leaf Extract, Antidiabetic.

scholarly journals Anti-obesity Activity Tin Leaf Extract (Ficus carica Linn) on the Rats given High Fat Diets

2019 ◽  
Vol 17 (1) ◽  
pp. 81
Author(s):  
Errol Rakhmad Noordam ◽  
Swasono R. Tamat ◽  
Syamsudin Syamsudin
Keyword(s):  
Body Weight ◽  
Leaf Extract ◽  
Test Group ◽  
The Body ◽  
Ficus Carica ◽  
Sprague Dawley ◽  
High Fat ◽  
Sprague Dawley Rats ◽  
Average Body ◽  
Average Body Weight

Obesity is a health problem in the community because it can cause a risk of degenerative diseases such as type 2 diabetes mellitus, high blood pressure, heart disease, cancer, and atherosclerosis. Unhealthy lifestyles such as lack of physical activity by exercising, a diet high in carbohydrates and fats, can cause fat deposits in the body, especially in the abdomen. The use of chemical drugs such as Orlistat as a weight loss or to help reduce the risk of regaining lost weight, is less effective because it requires a long consumption time and the presence of side effects. Tin leaf content (Ficus carica Linn) is flavonoids, alkaloids, tannins and steroids, tin leaf extract has IC50 150mg/L antioxidant activity. This study was to determine the anti-obesity activity of tin leaf extract in male Sprague-Dawley rats given a high fat diet. 30 Sprague-Dawley rats were classified into 6 groups. The results obtained, in the group dose of 100 mg / kg obtained an average body weight of 381.8 grams, the test group 200 mg / kg obtained an average body weight of 414.5 grams, in the test group 400 mg / kg obtained 387 grams. The conclusion of this study is that the activity of Tin leaf extract (Ficus carica Linn) can be used as an anti-obesity.

scholarly journals Phytochemical Evaluation and Anti-Diabetic Effects of Ethanolic Leaf Extract of Petersianthus macrocarpus on Streptozotocin-Induced Diabetic Rats

2021 ◽  
pp. 39-47
Author(s):  
Aligwekwe A. Ugochukwu ◽  
Idaguko C. Anna
Keyword(s):  
Blood Glucose ◽  
Cardiac Glycoside ◽  
Wistar Rats ◽  
Cardiac Glycosides ◽  
Leaf Extract ◽  
Diabetic Control ◽  
Islet Of Langerhans ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Ethanolic Leaf Extract

Aim: The purpose of this study was to evaluate the antidiabetic effect of ethanolic extracts of Petersianthus macrocarpus leaf and its phytochemical analysis using different solvents. Place and Duration of Study: The study was carried out between March and September in 2018 in the Department of Anatomy, Madonna University, Elele. River State, Nigeria. Materials and Methods: Twenty five Wistar rats, weighing between 200-225g were divided into five groups of five rats.  Group A (Control) while Groups B, C, D and E were induced with diabetes using streptozotocin firstly 35mg/kg b.w; and 2 weeks later 25mg/kg b.w.  Group B (Diabetic control), Group C received 0.5mg/kg b.w of Glibenclamide. Groups D and E received daily 50 and 100 mg/kg b.w of ethanolic leaf extract of P. macrocarpus orally for two weeks. The fasting blood glucose levels were determined weekly for two weeks. At the end of the experiment, the animals were sacrificed and the pancreas was removed for histological procedures. Results: The body weights increased significantly (P<0.05) in 100 mg/kg b.w group when compared to the diabetic control rats weight at the end of the experiment. Also there was a significantly decreased (P<0.05) in blood glucose levels in P. macrocarpus (100mg/kg b.w). The histological section of the pancreas of diabetic control showed eosinophilic material in the islet, shrinkage of the islet of Langerhans while the group treated with 100 mg/kg of extract showed granulated and well prominent pancreatic islet of Langerhans. Phytochemical screening showed methanolic extract of P. macrocarpus leaf having alkaloid, saponin, tannin, phenol, flavonoid, cardiac glycoside, steroids, terpenoids, anthocyanin and anthraquinone. However, cardiac glycosides and steroids were absent in ethanolic extract. Cardiac glycoside and terpenoids were also absent in hexane and acetone extract, while phenol, cardiac glycosides, steroids and anthrocyanin were absent in the water extract. Conclusion: Ethanolic leaf extract of P. macrocarpus ameliorate streptozotocin-induced diabetes in Wistar rats.

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