Results of vitamin and mineral complexes’ use during pregnancy (literature review)

2020 ◽  
pp. 39-46
Author(s):  
I. V. Kuznetsova

The purpose of this review was to study the effect of the intake of vitamin and mineral complexes (VMC) by pregnant women on obstetric and perinatal outcomes. To carry out the analysis, a search was carried out in foreign and domestic publications in the international citation system PubMed, published over the past 15 years. The results of the analysis showed that the use of VMC within 3 months before conception and during pregnancy reduces the risks of intrauterine abnormalities and improves the prognosis of postnatal development of offspring. In addition, taking VMC during gestation reduces the incidence of iron deficiency anemia in pregnant women, intrahepatic cholestasis of pregnant women, preeclampsia, macrosomia, low birth weight, premature birth and postpartum hemorrhage. The use of multicomponent VMC has advantages over taking only folic acid and iron. Conclusion. Taking an VMC during pregnancy can significantly reduce the risk of adverse obstetric and perinatal outcomes. The use of complex drugs is especially important at the stage of preconception and early pregnancy, but it is advisable to continue until the end of pregnancy and lactation.

2019 ◽  
Vol 15 (2) ◽  
pp. 143-149 ◽  
Author(s):  
Harpriya Kaur ◽  
Delf Schmidt-Grimminger ◽  
Baojiang Chen ◽  
K.M. Monirul Islam ◽  
Steven W. Remmenga ◽  
...  

Background: Pregnancy may increase the risk of Human Papillomavirus (HPV) infection because of pregnancy induced immune suppression. The objective of this study was to use a large population-based dataset to estimate the prevalence of HPV infection and its association with adverse outcomes among pregnant women. Methods: We analyzed Pregnancy Risk Monitoring System data from 2004-2011 (N=26,085) to estimate the self-reported HPV infection. Survey logistic procedures were used to examine the relationship between HPV infection and adverse perinatal outcomes. Results: Approximately 1.4% of women were estimated to have HPV infection during their pregnancy. The prevalence of adverse outcomes in this sample was preterm birth (8.4%), preeclampsia (7.5%), low birth weight (6.3%) and premature rupture of membranes (2.8%). Compared to women without HPV infection, HPV infection positive women were much more likely to have had other infections such as chlamydia (9.23% vs. 2.12%, p-value <.0001), Group B Strep (21.7% vs. 10.04%, p-value <.0001), and herpes (7.17% vs. 1.07%, p-value <.0001). After adjusting for other risk factors including other infections, HPV infection was significantly associated with low birth weight (OR: 1.94, 95% CI: 1.14-3.30). Conclusion: The study indicated a potential association between HPV infection and low birth weight. Because pregnant women with HPV infection are at higher risk of other infections, future research may focus on the roles of co-infection in the development of adverse perinatal effects.


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Erica Sedlander ◽  
Chandni Ladwa ◽  
Sameera Talegawkar ◽  
Rohini Ganjoo ◽  
Rajiv Rimal

Abstract Objectives Half of women of reproductive age in India have iron deficiency anemia compared to only 23% of men. Most research focuses on biological reasons for this discrepancy and access to iron-folic acid and iron-rich foods. However, recent research in India shows that inequitable gender norms may affect a woman's ability or desire to take iron supplements and to eat iron-rich food. The objective of this study is to examine how and why gender norms may be affecting high and persistent rates of anemia in India. Methods We conducted 25 key informant interviews and 16 focus group discussions with women of reproductive age, adolescents, husbands and mothers-in-law (n = 148) in Odisha, India. We purposively sampled key informants and randomly sampled focus group participants. We analyzed the data using applied thematic analysis in Nvivo software. Results Our data shows that unequal gender norms impact behaviors that are directly related to high rates of anemia. Women are often serving their husband, children, and in-laws first and “adjusting” to whatever is leftover which may be poor in nutritional qualities and less iron rich. Men are also the main breadwinners but often spend their money on alcohol, money that could be spent on iron-rich food for the household. Women reported that extreme fatigue is a normal part of being a woman and that a woman's plight is to take care of her family at any cost. Given that fatigue, the primary symptom of anemia is normalized; women may be less likely to seek treatment. Women tend to prioritize the health of their family over her own which could affect her ability or desire to go to the health center to get tested for anemia or to obtain iron supplements. Pregnant women are more likely to take iron supplements for the health of the baby, not her own health. While non-pregnant women of reproductive age who were not diagnosed with anemia were not focused on preventive health, only major illnesses and thus, were not taking supplements at all. Conclusions More upstream barriers, like gender norms, may be impinging on a woman's ability to take iron folic acid and to eat iron rich foods. Understanding how gender norms contribute to anemia could change the narrative from a biomedical issue to a social justice issue. Funding Sources The Bill and Melinda Gates Foundation. Supporting Tables, Images and/or Graphs


2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Negussie Boti ◽  
Tezera Bekele ◽  
Wanzahun Godana ◽  
Eskeziyaw Getahun ◽  
Feleke Gebremeskel ◽  
...  

Background. Iron deficiency anemia among pregnant women is one of the most common public health problems in developing country particularly in Ethiopia. Iron/folic acid supplementation with optimal adherence is the main cost-effective strategy for prevention and control of iron deficiency anemia in pregnant women. However, level of adherence to iron/folic acid supplementation and its associated factors were not well identified in study area. Therefore, the aim of this study was to determine the level of adherence to iron/folic acid supplementation and associated factors among pregnant women in Burji Districts, southern Ethiopia. Methods. A community-based cross-sectional study was conducted among 317 pregnant women in Burji Districts from March to April 2017 using interviewer administered questionnaires. Data were entered into Epi Info 3.5.1 and exported to SPSS version 20.0 for analysis. Binary and multivariable logistic regression was used to identify factors associated with iron/folic acid supplementation. Adjusted odds ratio (AOR) with 95% confidence interval (CI) and p-value <0.05 were used to declare statistical significance. Results. Among women participating in the study, 163(51.4%) were adherent to iron/folate acid supplementation. Factors significantly associated with adherence to iron and folic acid supplementation were maternal educational status (AOR: 2.47, 95% CI: 1.13-4.97), early registration for ANC (AOR: 2.49, 95% CI: 1.45 – 4.27), history of anemia during current pregnancy (AOR: 2.02, 95% CI: 1.09-3.72), and knowledge about iron and folic acid supplementation (AOR: 1.96, 95% CI: 1.02-3.76). Forgetfulness and fear of side effects were among the leading reasons of pregnant women for nonadherence to iron and folic acid supplementation. Conclusions. This study revealed that adherence to iron /folic acid supplementation was found to be 51.4%. Maternal educational status, early registration for ANC, history of anemia during current pregnancy, and knowledge about iron and folic acid supplementation were significant factors associated with adherence to iron/folic acid supplementation among pastoralist’s pregnant women. Therefore, anemia prevention strategy should include strengthening giving awareness, counseling, strengthening community health education, and participation in health programs which are necessary to improve the uptake of iron/folic acid supplements.


2019 ◽  
Vol 8 (1) ◽  
pp. 93
Author(s):  
Faradina Aghadiati ◽  
Diffah Hanim ◽  
Yulia Lanti Retno Dewi

The birth weight (BW) are utilized as indicators of the healthy and term newborns. Factor that affects the weight of a newborn are micronutrient intake and fundal height. Folic acid and iron (Fe) were associated with newborn birth weight. Fundal height in <em>centimeters</em> (cm) is the same as the gestational age of the week, the fundal height that is not in accordance with the gestational age is leading to stunted fetal growth. The purpose of this study was to analyze the relationship between intake of folic acid, iron (Fe) and fundal height with newborn birth weight. This research method was an analytic observational using a <em>cross-sectional</em> approach. The sample in this study were 114 pregnant women living in Yogyakarta. Statistical test results proved a significant relationship between the intake of folic acid and iron (Fe) with the newborn birth weight (p &lt; 0.05). There was a significant relationship between the fundal height with the newborn birth weight (p &lt; 0.05). The concludes of this study, pregnant women with adequate folic acid intake, adequate iron intake and normal fundal height tended to give birth newborns with normal birth weight.


2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Dwi Retna Prihati ◽  
Gita Kostania

Abstract: MMN, Newborn Baby Weight. During pregnancy food is required with good quality and quantity to meet the nutritional needs of mother and baby. The low nutritional status of pregnant women during pregnancy can lead to various adverse effects for mothers and infants, such as those born with Low Birth Weight (LBW). LBW babies have a 10 to 20 times greater chance of dying than babies born with enough birth weight. Multiple Micro Nutrient (MMN) contains 15 types of vitamins and minerals most important for pregnant women, including vitamin A, vitamin E, vitamin D, vitamin B1, vitamin B2, niacin, Vitamin B6, vitamin B12, folic acid, vitamin C, Fe , folic acid, Zink, Copper, Selenium, and Iodine. MMN is one of the nutrients to prevent the occurrence of anemia because in MMN there are factors forming Hemoglobin ie Fe, Vitamin B12 and folic acid. The availability of adequate hemoglobin makes the metabolic system work well. Lack of hemoglobin not only affects the health of the mother but also affects the health of the fetus it contains, including the growth of the fetal inhibition (such as weight, body length). The purpose of this study was to prove the effect of MMN on newborn weight in Pandes Klaten village. This type of research is arestrospective study with cross sectional design. The subjects of this study were BBL (newborn) whose mother consumed MMN during pregnancy. Different test sing Independent T-test to compare control group and treatment group. Significant value in this study was p <0.05. The results of this study were no significant difference between birth weight between control group and MMN treatment group (P = 0.879). In conclusion MMN has no significant effect on newborn weight gain.


2019 ◽  
Vol 17 (6) ◽  
pp. 884-895 ◽  
Author(s):  
Funanani Mashau ◽  
Esper Jacobeth Ncube ◽  
Kuku Voyi

Abstract The current study aimed to determine the association between trichloroacetic acid (TCAA) levels and adverse pregnancy outcomes among third-trimester pregnant women who were exposed to chlorinated drinking water. A total of 205 pregnant women who participated in the disinfection by-products exposure and adverse pregnancy outcome study in South Africa were randomly asked to participate in this study by providing their morning urine sample voids. Samples were analysed for urinary creatinine and TCAA. Furthermore, participants gave individual data using a structured questionnaire. The mean (median) concentration of creatinine-adjusted urinary TCAA was 2.34 (1.95) μg/g creatinine. Elevated levels of creatinine-adjusted TCAA concentrations showed an increased risk of premature birth, small for gestational age (SGA) and low birth weight. There was no significant statistical correlation observed between creatinine-adjusted TCAA concentrations and the total volume of cold water ingested among the study population. No statistically significant association was observed between creatinine-adjusted urinary TCAA and premature birth, SGA and low birth weight newborns among the study subjects. However, the urinary TCAA concentrations identified in this study suggest potential health risks towards women and foetus. Therefore, further studies are warranted to prevent further adverse pregnancy outcomes.


2019 ◽  
Vol 28 (4) ◽  
pp. 322-8
Author(s):  
Hindra Irawan Satari ◽  
Mita Puspita ◽  
Julitasari Sundoro ◽  
Andrijono ◽  
Syafriyal ◽  
...  

BACKGROUND The Indonesian Expanded Program of Immunization has implemented tetanus and diphtheria (Td) vaccination to replace the tetanus toxoid vaccine in pregnant women since the year 2016. Td vaccine is administered to protect against diphtheria and tetanus to the mother and her baby as well. This prospective study was conducted to assess the adverse reactions after Td immunization; besides, a retrospective study was conducted to observe the presence of severe local reaction (Arthus reaction), premature birth, and low birth weight history in the medical records of pregnant women who had received Td immunization in the past year. METHODS A prospective observational study was conducted in 200 pregnant women. Local reactions and systemic events occurring within 28 days after immunization were recorded in the diary card and were confirmed by the health worker in the follow-up visit. A retrospective study was also conducted to evaluate 750 medical records of pregnant women who had received Td immunization. The study was conducted fromSeptember 2017 to January 2018. The study has been registered at ClinicalTrials.gov ID: NCT03383653. RESULTS In 185 pregnant women who completed the study, the most common local reaction was pain, occurring in 33.5% of subjects within 24 hours after vaccination. Fever, other systemic reactions, and serious adverse events were not reported during the observation. In the retrospective study, 647 medical records were validated. No Arthus reaction was observed. The prevalence of premature birth was 1.24%, and that of low birth weight was 2.63%, which were below the normal rates. CONCLUSIONS Td vaccination in pregnant women was safe and well-tolerated.


2014 ◽  
Vol 63 (3) ◽  
pp. 58-65
Author(s):  
Svetlana Anatolyevna Vetushenko ◽  
Tatyana Grigoryevna Zakharova

The purpose of researches - to reveal clinical manifestations of obstetric complications at pregnant women with tuberculosis of various localization on the basis of results of medical monitoring, and also to establish the complications of fetoplatsentarny insufficiency taking place in the studied period, at pregnant women with tuberculosis according to localizations of tubercular process. During medical monitoring stories of families of 210 women with tuberculosis of various localization and a condition of their newborns during 2006-2013 on the basis of interdistrict maternity hospital N 4 of Krasnoyarsk, profiled on this pathology are analysed. As a result of the analysis of structure of obstetric complications at women with tuberculosis in the territory of Krasnoyarsk Kray it is established: from 210 pregnant women at 76 there were no complications; at 133 pregnant women with FPN clinical manifestations are noted it are 43 cases of a hypoxia of a fruit, 31 cases of SZRP, 14 cases of SZRP with a hypoxia, thus clinical manifestations were accompanied by lack of water and abundance of water at the level of 22 and 4 cases respectively; in the same group the increase in number of complications of pregnancy by a preeklampsiya, anomalies of patrimonial activity, premature birth at the level of 51, 16 and 28 cases respectively is looked through. From only 133 pregnant women with placentary insufficiency 11 cases of childbirth without clinical manifestations of FPN are noted. The revealed number of clinical manifestations of placentary insufficiency and other complications of pregnancy says that at pregnant women with a disease of tuberculosis these indicators many times is more, than at pregnant women without disease of tuberculosis. The established structure of obstetric complications at pregnant women with tuberculosis of various localization highlighted prevalence of FPN proceeding with heavy clinical manifestations, such as SZRP, the fruit hypoxia, and also revealed most often meeting complications of pregnancy, such as a preeklampsiya, abnormal patrimonial activity, premature birth. It is the indication for development of effective measures of prevention and treatment of these complications, their forecasting from early terms of pregnancy for improvement of perinatal outcomes.


2017 ◽  
Vol 10 (17) ◽  
pp. 177 ◽  
Author(s):  
Christiana R Titaley ◽  
Enrika Rahayu ◽  
Rita Damayanti ◽  
Dini Dachlia ◽  
Ratu Ayudewi Sartika ◽  
...  

 Objective: In Indonesia, pregnant women are recommended to take a minimum of 90 tablets of iron/folic acid (IFA), to prevent iron deficiency anemia. Our analysis aimed at examining the extent to which improved knowledge on IFA supplementation is associated with women’s compliance with taking a minimum of 90 IFA tablets during their last pregnancy in four districts in Indonesia.Methods: Data were derived from a cross-sectional study conducted in four districts, that is, Lebak and Pandeglang District (Banten Province) as well as Purwakarta and Subang District of West Java Province, Indonesia on June 2014. We used information from 436 mothers who delivered their baby in the last 6 months from the time of the survey and received at least 90 IFA tablets during her last pregnancy. Logistic regression analysis was used to examine the role of knowledge after controlling for confounders and other significant predictor on compliance with taking a minimum of 90 IFA tablets during pregnancy.Result: Significant association was found between knowledge of IFA supplements and compliance. Compared to women with poor knowledge of IFA supplementation, the odds of taking a minimum of 90 IFA tables increased by almost 100% in women with moderate knowledge (adjusted odd ratio [aOR]=1.96, 95% confidence interval [CI]: 1.17-3.30, p=0.011); and by more than four times (aOR=5.42, 95% CI: 1.76-16.68, p=0.003) in women with good knowledge of IFA supplementation. Other factors associated with compliance was attendance in at least four antenatal services (aOR=5.71, 95% CI: 1.28-25.53, p=0.023) and pregnant women experience of no side effects resulting from taking IFA tablets during pregnancy (aOR=2.70, 95% CI: 1.63-4.46, p<0.001).Conclusions: Efforts to increase women’s knowledge on IFA supplementation through community-based education will increase women’s compliance of taking IFA supplements. Strengthening counseling services on potential side effects of IFA supplementation and ways to manage them will also help to improve compliance.


Author(s):  
Monjurul Hoque ◽  
Shahnaz Hoque

Background: Teenage pregnancy is a known risk factor for a negative pregnancy outcome and poses a health risk to teenagers; it is thus considered a public health problem. It is also an indicator of problems with the sexual and reproductive health of a country’s young population. In South Africa, most of the adolescent pregnancies are to be found within the context of unstable relationships with the father of the baby and are unplanned or unwanted.Objectives: This study estimates and compares the incidence of adverse obstetric and perinatal outcomes of teenage women with older women, to identify specific health needs of teenage mothers during pregnancy and delivery.Methods:A retrospective cohort study targeted pregnant women who delivered at Empangeni Hospital from April to December 2005, whilst comparing the obstetric and perinatal outcomes of all teenage (ages < 19 years) pregnant women with those of older pregnant women (ages ≥ 19 years) for this study period. Data were collected from the labour ward delivery registry. Pearson’s chi-square test was performed to measure the level of significance (alpha = 0.05) for association amongst variables. The student t-test was used to find the significance difference between two proportions and the binary logistic regression method was employed to find the significant predictor for outcome variables.Results:There were 7836 deliveries over the study period, of which 1236 (16%) were teenage mothers.The rate of gestational age at delivery (e.g. pre-term delivery of 12%), vaginal and forceps deliveries,foetal presentation at birth, multiple pregnancies, low birth-weight and live births deliveries and mean Apgar scores were similar for both groups. The caesarean delivery rate (20%) and macerated stillbirth rate (1.1%) were significantly lower (p < 0.05) for teenagers than for older women.Conclusion: Although there was a higher rate of teenage pregnancy, it did not appear that it was associated with extra perinatal negative outcome such as preterm delivery, low birth-weight delivery and stillbirth. However, strategies are urgently needed to delay conception and improve the socio-economic development of teenage girls.


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