scholarly journals Jatrorrhizine: A Review of Sources, Pharmacology, Pharmacokinetics and Toxicity

2022 ◽  
Vol 12 ◽  
Author(s):  
Furong Zhong ◽  
Yang Chen ◽  
Jia Chen ◽  
Hailang Liao ◽  
Yirou Li ◽  
...  

Jatrorrhizine, an isoquinoline alkaloid, is a bioactive metabolite in common medicinal plants, such as Berberis vernae Schneid., Tinospora sagittata (Oliv.) Gagnep. and Coptis chinensis Franch. These plants have been used for centuries in traditional medicine for their wide-ranging pharmacological properties. This review emphasizes the latest and comprehensive information on the sources, pharmacology, pharmacokinetics and toxicity of jatrorrhizine. Studies on this alkaloid were collected from scientific internet databases, including the Web of Science, PubMed, ScienceDirect, Google Scholar, Elsevier, Springer, Wiley Online Library and Europe PMC and CNKI, using a combination of keywords involving “jatrorrhizine”, “sources”, “pharmacology,” “pharmacokinetics,” and “toxicology”. Jatrorrhizine exhibits anti-diabetic, antimicrobial, antiprotozoal, anticancer, anti-obesity and hypolipidemic properties, along with central nervous system activities and other beneficial activity. Studies of jatrorrhizine have laid the foundation for its application to the treatment of various diseases, but some issues still exist. Further investigations might emphasize 1) specific curative mechanisms of jatrorrhizine and clinical utility, 2) application prospect in the treatment of metabolic disorders, 3) comprehensive investigations of the toxicity mechanisms and 4) interactions of jatrorrhizine with other pharmaceuticals and development of derivatives.

Author(s):  
Ninh The Son ◽  
Abdelsamed I. Elshamymistry

: Genus Erythrina belongs to family Fabaceae, which widely distributed in tropical and subtropical areas, and has been applied in both traditional herbal medicines, and pharmacological uses. Original research articles and publications on overview of alkaloids related to this genus are available, but a supportive systematic review account highlighted phytochemical aspects of other types of secondary metabolites is now insufficient. Utilizing data information from SCI-Finder, Google Scholar, the Web of Science, Scopus, Science Direct, PubMed, Chemical Abstracts, ACS journals, Springer, Taylor Francis, Bentham Science and IOP Science, the reliable material sources of this systematic manuscript paper were obtained from the literature published from 1980s to now. A vast amount of data showed that the non-alkaloidal secondary metabolites obtained from genus Erythrina with various classes of chemical structures. Herein, approximately five hundred constituents were isolated comprising of flavonoids, terpenoids, saponins, phytosterols, phenols, arylbenzofurans, coumarins, alcohols, ceramides, mono-sugars and fatty acid derivatives. It resembles the previously phytochemical reports on the plants of differential genus of family Fabaceae, flavonoids reached to the high amount in plants of genus Erythrina. Numerous biological researches such as anti-microbacteria, anti-cancer, anti-virus using isolated compounds from Erythrina species suggested that secondary metabolites of Erythrina plants are now becoming promising agents for drug developments.


Author(s):  
Дмитрий Рубвальтер ◽  
Dmitry Rubvalter ◽  
Александр Либкинд ◽  
Alexander Libkind ◽  
Валентина Маркусова ◽  
...  

A multidimensional analysis of the state of Russian studies on the education issues over 1993–2016 was carried out based on the materials of the data contained in the Web of Science (SSCI, A & HCI and SCI-E databases). There were determined the dynamics and trends of a number of relevant indicators, such as the number of Russian publications by year, the share of these publications in the global flow of publications on education issues, the dynamics of the share of publications made in co-authorship with foreign colleagues, etc. A number of distributions of Russian publications on educational issues was compiled and analyzed: by journals, by Russian regions and cities, by organizations and authors of the publications. It was found that most of these distributions were characterized by a high level of non-uniformity. A list of journals (125 titles) in which Russian works on education issues had been published was compiled. Russian organizations (308) and domestic researchers (about two thousand) engaged in studying the issues of education were identified. It was discovered that more than 200 organizations and about 400 academicians from 60 foreign countries had participated in Russian studies on the education issues.


Author(s):  
Priscilla Paola Severo ◽  
Leonardo B. Furstenau ◽  
Michele Kremer Sott ◽  
Danielli Cossul ◽  
Mariluza Sott Bender ◽  
...  

The study of human rights (HR) is vital in order to enhance the development of human beings, but this field of study still needs to be better depicted and understood because violations of its core principles still frequently occur worldwide. In this study, our goal was to perform a bibliometric performance and network analysis (BPNA) to investigate the strategic themes, thematic evolution structure, and trends of HR found in the Web of Science (WoS) database from 1990 to June 2020. To do this, we included 25,542 articles in the SciMAT software for bibliometric analysis. The strategic diagram produced shows 23 themes, 12 of which are motor themes, the most important of which are discussed in this article. The thematic evolution structure presented the 21 most relevant themes of the 2011–2020 period. Our findings show that HR research is directly related to health issues, such as mental health, HIV, and reproductive health. We believe that the presented results and HR panorama presented have the potential to be used as a basis on which researchers in future works may enhance their decision making related to this field of study.


Author(s):  
Leonardo B. Furstenau ◽  
Bruna Rabaioli ◽  
Michele Kremer Sott ◽  
Danielli Cossul ◽  
Mariluza Sott Bender ◽  
...  

The COVID-19 pandemic has affected all aspects of society. Researchers worldwide have been working to provide new solutions to and better understanding of this coronavirus. In this research, our goal was to perform a Bibliometric Network Analysis (BNA) to investigate the strategic themes, thematic evolution structure and trends of coronavirus during the first eight months of COVID-19 in the Web of Science (WoS) database in 2020. To do this, 14,802 articles were analyzed, with the support of the SciMAT software. This analysis highlights 24 themes, of which 11 of the more important ones were discussed in-depth. The thematic evolution structure shows how the themes are evolving over time, and the most developed and future trends of coronavirus with focus on COVID-19 were visually depicted. The results of the strategic diagram highlight ‘CHLOROQUINE’, ‘ANXIETY’, ‘PREGNANCY’ and ‘ACUTE-RESPIRATORY-SYNDROME’, among others, as the clusters with the highest number of associated citations. The thematic evolution. structure presented two thematic areas: “Damage prevention and containment of COVID-19” and “Comorbidities and diseases caused by COVID-19”, which provides new perspectives and futures trends of the field. These results will form the basis for future research and guide decision-making in coronavirus focused on COVID-19 research and treatments.


2021 ◽  
Vol 30 (2) ◽  
pp. 117-128
Author(s):  
Leena Sachdeva ◽  
Kumkum Bharti ◽  
Mridul Maheshwari

Despite the proliferation of occupational segregation research, only a limited amount has explored it from a gender perspective. The attention that has been given is widely scattered and requires an analysis to identify the major works undertaken and the changes over time. This study aimed to examine and assimilate articles published on gender-based occupational segregation through a bibliometric analysis. The study examined 512 articles published from the early 1970s to 2020 that were retrieved from the Web of Science database. The findings suggest that gender and occupational segregation remain an extensive field of research, although this research comes mainly from North American and European countries. The low representation from developing countries indicates that more research is needed based on these different socio-cultural settings. This study identified three dominant research clusters, namely gendered organisational structures and systems, measurement of occupational segregation, and wage differential. Studies also covered areas including conceptualization, LGBTQ issues, and the role of legislation and institutions in reducing workplace inequalities; thus, providing a direction for scholars and practitioners.


Author(s):  
Beatriz Tarazona‐Álvarez ◽  
Andres López‐Roldan ◽  
Antonio Vidal‐Infer ◽  
Daniel López‐Padilla ◽  
Adolfo Alonso‐Arroyo

2018 ◽  
Vol 10 ◽  
pp. 117957351881354 ◽  
Author(s):  
Thais Massetti ◽  
Talita Dias da Silva ◽  
Tânia Brusque Crocetta ◽  
Regiani Guarnieri ◽  
Bruna Leal de Freitas ◽  
...  

Background: Virtual reality (VR) experiences (through games and virtual environments) are increasingly being used in physical, cognitive, and psychological interventions. However, the impact of VR as an approach to rehabilitation is not fully understood, and its advantages over traditional rehabilitation techniques are yet to be established. Method: We present a systematic review which was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). During February and March of 2018, we conducted searches on PubMed (Medline), Virtual Health Library Search Portal databases (BVS), Web of Science (WOS), and Embase for all VR-related publications in the past 4 years (2015, 2016, 2017, and 2018). The keywords used in the search were “neurorehabilitation” AND “Virtual Reality” AND “devices.” Results: We summarize the literature which highlights that a range of effective VR approaches are available. Studies identified were conducted with poststroke patients, patients with cerebral palsy, spinal cord injuries, and other pathologies. Healthy populations have been used in the development and testing of VR approaches meant to be used in the future by people with neurological disorders. A range of benefits were associated with VR interventions, including improvement in motor functions, greater community participation, and improved psychological and cognitive function. Conclusions: The results from this review provide support for the use of VR as part of a neurorehabilitation program in maximizing recovery.


2018 ◽  
Vol 218 (4) ◽  
pp. 212
Author(s):  
R. Barredo Torices ◽  
M. López Berlanga ◽  
I. de Mier Barragán ◽  
J. Arenas Barbero

2021 ◽  
Vol 13 (7) ◽  
pp. 3616
Author(s):  
Víctor-Manuel Muñoz-Sánchez ◽  
Antonio-Manuel Pérez-Flores

This paper addresses the field of study relating to ecological values and the production, distribution, and consumption of organic food products, aiming to contribute to the consolidation of scientific knowledge in this area of study. This article refers to a bibliographic review in the Web of Science database. It also involves bibliometric analysis of the results of this bibliographic review using the NVivo program. The main results classify the number of articles published on the basis of the methodology used, the number of countries in the analysis units, the central themes of the study, and the type of organic food considered in the bibliography analyzed. It also classifies the articles with the greatest impact in relation to the number of bibliographic references, in addition to detailing the universities, institutions, and journals with the largest number of contributions in the field of study. The research concludes by identifying that most of the articles apply a quantitative methodology and address generic aspects of organic food. This study identifies a need for further research in relation to specific organic foods, and for articles that introduce comparative analysis at the international level.


Sign in / Sign up

Export Citation Format

Share Document