Flavonoids and other Non-Alkaloidal Constituents of Genus Erythrina: A Detailed Account of Phytochemical Review

2019 ◽  
Vol 23 ◽  
Author(s):  
Ninh The Son ◽  
Abdelsamed I. Elshamymistry
Keyword(s):  
Secondary Metabolites ◽  
Web Of Science ◽  
Herbal Medicines ◽  
Original Research ◽  
Chemical Structures ◽  
Fatty Acid Derivatives ◽  
Material Sources ◽  
Anti Cancer ◽  
Alkaloidal Constituents ◽  
The Web

: Genus Erythrina belongs to family Fabaceae, which widely distributed in tropical and subtropical areas, and has been applied in both traditional herbal medicines, and pharmacological uses. Original research articles and publications on overview of alkaloids related to this genus are available, but a supportive systematic review account highlighted phytochemical aspects of other types of secondary metabolites is now insufficient. Utilizing data information from SCI-Finder, Google Scholar, the Web of Science, Scopus, Science Direct, PubMed, Chemical Abstracts, ACS journals, Springer, Taylor Francis, Bentham Science and IOP Science, the reliable material sources of this systematic manuscript paper were obtained from the literature published from 1980s to now. A vast amount of data showed that the non-alkaloidal secondary metabolites obtained from genus Erythrina with various classes of chemical structures. Herein, approximately five hundred constituents were isolated comprising of flavonoids, terpenoids, saponins, phytosterols, phenols, arylbenzofurans, coumarins, alcohols, ceramides, mono-sugars and fatty acid derivatives. It resembles the previously phytochemical reports on the plants of differential genus of family Fabaceae, flavonoids reached to the high amount in plants of genus Erythrina. Numerous biological researches such as anti-microbacteria, anti-cancer, anti-virus using isolated compounds from Erythrina species suggested that secondary metabolites of Erythrina plants are now becoming promising agents for drug developments.

Flavonoids and other Non-Alkaloidal Constituents of Genus Erythrina: Phytochemical Review

2020 ◽  
Vol 23 ◽  
Author(s):  
Ninh The Son ◽  
Abdelsamed I. Elshamy
Keyword(s):  
Systematic Review ◽  
Secondary Metabolites ◽  
Herbal Medicines ◽  
Original Research ◽  
Chemical Structures ◽  
Fatty Acid Derivatives ◽  
Material Sources ◽  
Anti Cancer ◽  
The Family ◽  
Alkaloidal Constituents

Background: Genus Erythrina belongs to the family Fabaceae, which is widely distributed in tropical and subtropical areas. It has been used in both traditional herbal medicines and pharmacological applications. Original research articles and publications on the overview of alkaloids related to this genus are available, but a supportive systematic review account that highlights phytochemical aspects of other types of secondary metabolites is currently insufficient. Objective: With the utilization of data and information from SCI-Finder, Google Scholar, the Web of Science, Scopus, Science Direct, PubMed, Chemical Abstracts, ACS journals, Springer, Taylor Francis, Bentham Science, and IOP Science, the reliable material sources of this systematic review paper were obtained from various literature published from the 1980s to present. Conclusion: A vast amount of data showed that the non-alkaloidal secondary metabolites were obtained from genus Erythrina with various classes of chemical structures. Herein, approximately five hundred constituents were isolated, including flavonoids, terpenoids, saponins, phytosterols, phenols, arylbenzofurans, coumarins, alcohols, ceramides, monosugars, and fatty acid derivatives. In agreement with the previous phytochemical reports on the plants of the family Fabaceae, flavonoids make up a great percentage in the number of plants of genus Erythrina. Numerous biological activity investigations such as anti-bacteria, anti-cancer, anti-virus using isolated compounds from Erythrina species have suggested that secondary metabolites of Erythrina plants are now becoming the promising agents for drug developments.

Secondary Metabolites of Genus Pandanus: An Aspect of Phytochemistry

2019 ◽  
Vol 16 (7) ◽  
pp. 689-710 ◽  
Author(s):  
Ninh The Son
Keyword(s):  
Secondary Metabolites ◽  
Web Of Science ◽  
Herbal Medicines ◽  
Original Research ◽  
Food Chemistry ◽  
Nutrient Contents ◽  
The Family ◽  
Crucial Information ◽  
Chemical Products ◽  
Old World Tropics

Genus Pandanus belongs to the family Padanaceae, which is widely distributed in old world tropics and subtropics, and has been applied in traditional herbal medicines, pharmacological uses, food chemical products and handicrafts. Original research articles related to this genus are available but an insight account highlighted phytochemical aspects of secondary metabolites is now insufficient. The reliable sources of literature data for this systematic manuscript were obtained from the literatures published from 1960s to now, utilizing data information from ACS journals, Taylor Francis, Springer, IOP Science, SCI-finder, Chemical Abstracts, the Web of Science, Scopus, ScienceDirect, PubMed and Googlescholar. A vast amount of data showed that genus Pandanus contained various classes of the secondary metabolites. Herein, approximately 180 constituents were isolated, comprising alkaloids, phenols, lignans, steroids, terpenoids, lipids, flavonoids, coumarins, lactones and amino acids. In addition, the crucial information involved in food chemistry suggests that Pandanus species can also be a good candidate to provide essential oils and nutrient contents of vitamins and sugars.

scholarly journals Secondary Metabolites of the Genus Amycolatopsis: Structures, Bioactivities and Biosynthesis

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1884
Author(s):  
Zhiqiang Song ◽  
Tangchang Xu ◽  
Junfei Wang ◽  
Yage Hou ◽  
Chuansheng Liu ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Cyclic Peptides ◽  
Biosynthetic Pathway ◽  
Search Strategy ◽  
Web Of Science ◽  
Biological Activities ◽  
Chemical Structures ◽  
Anti Cancer ◽  
Unidentified Species ◽  
Amino Derivatives

Actinomycetes are regarded as important sources for the generation of various bioactive secondary metabolites with rich chemical and bioactive diversities. Amycolatopsis falls under the rare actinomycete genus with the potential to produce antibiotics. In this review, all literatures were searched in the Web of Science, Google Scholar and PubMed up to March 2021. The keywords used in the search strategy were “Amycolatopsis”, “secondary metabolite”, “new or novel compound”, “bioactivity”, “biosynthetic pathway” and “derivatives”. The objective in this review is to summarize the chemical structures and biological activities of secondary metabolites from the genus Amycolatopsis. A total of 159 compounds derived from 8 known and 18 unidentified species are summarized in this paper. These secondary metabolites are mainly categorized into polyphenols, linear polyketides, macrolides, macrolactams, thiazolyl peptides, cyclic peptides, glycopeptides, amide and amino derivatives, glycoside derivatives, enediyne derivatives and sesquiterpenes. Meanwhile, they mainly showed unique antimicrobial, anti-cancer, antioxidant, anti-hyperglycemic, and enzyme inhibition activities. In addition, the biosynthetic pathways of several potent bioactive compounds and derivatives are included and the prospect of the chemical substances obtained from Amycolatopsis is also discussed to provide ideas for their implementation in the field of therapeutics and drug discovery.

scholarly journals Uso de la espectroscopia de infrarrojo cercano para la medición de la saturación de oxígeno muscular en el deporte

2019 ◽  
Vol 0 (Avance Online) ◽  
Author(s):  
CD Gómez-Carmona ◽  
A Bastida-Castillo ◽  
J Pino-Ortega
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared ◽  
Web Of Science ◽  
Training Programs ◽  
Research Articles ◽  
Original Research ◽  
Inclusion Criteria ◽  
Bibliographic Search ◽  
Method Of Evaluation ◽  
The Web

RESUMEN El objetivo de este trabajo fue revisar el funcionamiento de la espectroscopia de infrarrojo cercano y sus diferentes aplicaciones en el ámbito deportivo como son: la descripción de las exigencias oxidativas mediante su monitorización tanto en contextos de resistencia y fuerza, y la evaluación de su aplicación en programas de entrenamiento. Para ello se realizó una búsqueda bibliográfica en las bases de datos Web of Science y Scopus en la que se obtuvieron, después de la exclusión de artículos que no se ajustaron a los criterios de inclusión, un total de 38 artículos originales de investigación. Los datos resultantes que fueron extraídos de los estudios incluidos fueron datos de los participantes, parámetros del programa de entrenamiento o ejercicio, los músculos evaluados, el dispositivo y método de evaluación y los principales resultados. ABSTRACT The objective of this research was to review the operation of near-infrared spectroscopy and its different applications in the sports field, such as: the description of oxidative requirements through its monitoring in both resistance and strength contexts and the evaluation of its application in training programs. A bibliographic search was carried out in the Web of Science and Scopus databases, in which a total of 38 original research articles were obtained after exclusion of articles that did not meet the inclusion criteria. The resulting data that were extracted from the included studies were data of the participants, parameters of the training program or exercise, the muscles evaluated, the device and method of evaluation and the main results. RESUMO O objetivo desta pesquisa foi revisar o funcionamento da espectroscopia do infravermelho próximo e suas diferentes aplicações no campo esportivo, tais como: a descrição dos requisitos oxidativos através de seu monitoramento em contextos de resistência e força e a avaliação de sua aplicação em programas de treinamento . Uma pesquisa bibliográfica foi realizada nas bases de dados da Web of Science e Scopus, no qual foram obtidos 38 artigos de pesquisa originais após a exclusão de artigos que não atendiam aos critérios de inclusão. Os dados resultantes que foram extraídos dos estudos incluídos foram dados dos participantes, parâmetros do programa de treinamento ou exercício, os músculos avaliados, o dispositivo e o método de avaliação e os principais resultados.

scholarly journals List of Most Significant Publications of Waclaw Szybalski

2021 ◽  
Author(s):  
Ewa Łojkowska
Keyword(s):  
Gene Therapy ◽  
Synthetic Biology ◽  
Web Of Science ◽  
Multiple Drug ◽  
Original Research ◽  
Strong Impact ◽  
Scientific Publications ◽  
Multiple Drug Therapy ◽  
The Web ◽  
Scientific Achievements

Professor Wacław Szybalski’s most significant scientific achievements are listed below in twenty-three points. He has authored over five hundred publications in the fields of chemistry, microbiology, molecular and synthetic biology, genetics, mutagenesis, and genetic engineering. Many of Professor Szybalski’s discoveries resulted from him first developing a series of original research techniques that then gave rise to new fields of science and novel concepts such as synthetic biology, gene therapy, and multiple drug therapy. The Web of Science, the most important database of scientific publications, lists 265 publications by Professor Szybalski that have been cited by other scientists over 12,000 times; his Hirsh index is 56, showing the strong impact of his work on science.

Neurotensins and their therapeutic potential: research field study

2020 ◽  
Vol 12 (19) ◽  
pp. 1779-1803
Author(s):  
Andy Wai Kan Yeung ◽  
Maya G Georgieva ◽  
Kiril Kirilov ◽  
Aneliya A Balacheva ◽  
Martina I Peeva ◽  
...  
Keyword(s):  
Core Collection ◽  
Web Of Science ◽  
Therapeutic Potential ◽  
Neurological Diseases ◽  
Research Field ◽  
Clinical Development ◽  
Original Research ◽  
Research Papers ◽  
The Web ◽  
Highly Cited

The natural tridecapeptide neurotensin has been emerged as a promising therapeutic scaffold for the treatment of neurological diseases and cancer. In this work, we aimed to identify the top 100 most cited original research papers as well as recent key studies related to neurotensins. The Web of Science Core Collection database was searched and the retrieved research articles were analyzed by using the VOSviewer software. The most cited original articles were published between 1973 and 2013. The top-cited article was by Carraway and Leeman reporting the discovery of neurotensin in 1973. The highly cited terms were associated with hypotension and angiotensin-converting-enzyme. The conducted analysis reveals the therapeutic potentials of neurotensin, and further impactful research toward its clinical development is warrantied.

scholarly journals Knee surgery: Trends and the 50 most cited articles

2019 ◽  
Vol 11 (4) ◽  
Author(s):  
David Zargaran ◽  
Alexander Zargaran ◽  
Sean Lobo ◽  
Zameer Shah
Keyword(s):  
Orthopedic Surgery ◽  
Core Collection ◽  
Web Of Science ◽  
High Impact ◽  
Knee Surgery ◽  
Orthopedic Procedures ◽  
Original Research ◽  
Exclusion Criteria ◽  
Bibliographic Analysis ◽  
The Web

Knee Surgery is one of the most commonly performed orthopedic procedures, and a rapidly evolving area of research. A bibliographic analysis was conducted to explore the characteristics of the top 50 most cited articles in knee surgery. The Web of Science Core Collection Database was used to search for Knee AND Surgery, further refined for orthopedic surgery, yielding 1,660 articles. After inclusion and exclusion criteria were applied, the top 50 cited articles were statistically and thematically analyzed. Year of publication ranged from 1982 to 2014. The highest volume of research came from USA, with the Journal of Bone and Joint Surgery having the highest number of papers in the top 50. The most common theme of research was Knee Arthroplasty Outcomes. Our study elucidates trends and popular areas of research in the field of knee surgery, and provides researchers with an overview of areas to focus, where there is scope for high-impact original research.

scholarly journals Phytochemical Properties and Pharmacological Role of Plants: Secondary Metabolites

2021 ◽  
Vol 18 (1) ◽  
pp. 23-35
Author(s):  
Bhupesh Kaushik ◽  
Jatin Sharma ◽  
Keshav Yadav ◽  
Prithik Kumar ◽  
Abhilasha Shourie
Keyword(s):  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Human Health ◽  
Herbal Medicines ◽  
Biotic And Abiotic Stress ◽  
Pharmacological Activities ◽  
Anti Cancer ◽  
Human Disorders ◽  
Ancient Times ◽  
Bioactive Phytochemicals

Over the past decades, there has been increasing attention tothe study of medicinal plants that contain many phytochemicals beneficial for human health. A number of secondary metabolites derived from various plants have been used as drug components to treat several human disorders since ancient times. The traditional therapeutic applications of secondary metabolites have been reported in the whole world. Numerous bioactive phytochemicals constituents have been identified and isolated using many advanced techniques. These bioactive phytochemicals are responsible for many pharmacological activities such as anti-inflammation, anti-cancer, anti-allergic, and antimicrobial infection. These secondary metabolites are not only beneficial for human health but also protect plants themselves from biotic and abiotic stress. These secondary metabolites are classified into many subclasses like terpenoids, alkaloids and phenolics. Each class of secondary metabolites has its pharmacological activities, which is required to be studied thoroughly for better use in pharmaceuticals, cosmetics, food, and other industries. Therefore, this review paper represents many medicinal plants that contain bioactive secondary metabolites and show pharmacological activities, which provides an opportunity to utilize them for improvement of human health and discover new herbal medicines.

Pharmacological Uses of the Plants Belonging to the Genus Commiphora

2020 ◽  
Vol 18 ◽  
Author(s):  
Subbiah Latha ◽  
Palanisamy Selvamani ◽  
Thangavelu Prabha
Keyword(s):  
Secondary Metabolites ◽  
Plant Species ◽  
Dna Cleavage ◽  
Structural Information ◽  
Chemical Constituents ◽  
Future Research ◽  
Pharmacological Properties ◽  
Chemical Structures ◽  
Indigenous Uses ◽  
Available Information

: Natural products have a unique place in the healthcare industry. The genus Commiphora emerged as a potential medicinal with huge benefits as evidenced through its use in various traditional and modern systems of medicine. Therefore, we aimed to prepare a concise review on the pharmacological activities and the indigenous uses of various plant species belonging to the genus Commiphora along with the structural information of various active botanical ingredients present in these plants based on the published literatures and scientific reports. To collect the various published literatures on Commiphora in various journals; to study and classify the available information on the pharmacological uses and chemical constituents; and to present the gathered information as a precise review to serve as a potential reference for future research. Pharmacological and phytochemical data on Commiphora plant species were collected from various journals, books, reference materials, websites including scientific databases, etc for compilation. This review article describes the various pharmacological properties of plants of Commiphora species viz., Anti-arthritic and anti-inflammatory, Anti-atherogenic, Antibacterial, Anti-coagulant, Anti-dicrocoeliasis, Anti-epileptic, Anti-fascioliasis, Anti-fungal, Anti-heterophyidiasis, Anti-hyper cholesterolemic, Anti-hyperlipidemic, Anti-hypothyroidism, Anti-obesity, Anti-osteoarthritic, Anti-osteoclastogenesis, Anti-oxidant, Anti-parasitic, Anti-pyretic, Anti-schistosomiasis, Anti-septic, Anti-thrombotic, Anti-ulcer, Cardioprotective, COX enzyme inhibitory, Cytotoxic /Anti-carcinogenic/Anti-cancer, DNA cleavage, Hypotensive, Inhibits lipid peroxidation, Inhibits NO and NO synthase production, Insecticidal, Local anesthetic, Molluscicidal, Smooth muscle relaxant, Tick repellent activities along with toxicity studies. Furthermore, the review also included various secondary metabolites isolated from various species of Commiphora genus along with their chemical structures serve as a ready resource for researchers. We conclude that the plant species belonging to the genus Commiphora possesses abundant pharmacological properties with a huge treasure of diverse secondary metabolites within themselves. This review indicates the necessity of further in-depth research, pre-clinical and clinical studies with Commiphora genus which may help to detect the unidentified potential of the Commiphora plant species.

Multidimensional analysis of the state of Russian studies on the education issues over 1993–2016

2018 ◽  
pp. 50-62
Author(s):  
Дмитрий Рубвальтер ◽  
Dmitry Rubvalter ◽  
Александр Либкинд ◽  
Alexander Libkind ◽  
Валентина Маркусова ◽  
...  
Keyword(s):  
Web Of Science ◽  
The State ◽  
Multidimensional Analysis ◽  
Russian Regions ◽  
Global Flow ◽  
Educational Issues ◽  
Foreign Countries ◽  
High Level ◽  
The Web ◽  
Made In

A multidimensional analysis of the state of Russian studies on the education issues over 1993–2016 was carried out based on the materials of the data contained in the Web of Science (SSCI, A & HCI and SCI-E databases). There were determined the dynamics and trends of a number of relevant indicators, such as the number of Russian publications by year, the share of these publications in the global flow of publications on education issues, the dynamics of the share of publications made in co-authorship with foreign colleagues, etc. A number of distributions of Russian publications on educational issues was compiled and analyzed: by journals, by Russian regions and cities, by organizations and authors of the publications. It was found that most of these distributions were characterized by a high level of non-uniformity. A list of journals (125 titles) in which Russian works on education issues had been published was compiled. Russian organizations (308) and domestic researchers (about two thousand) engaged in studying the issues of education were identified. It was discovered that more than 200 organizations and about 400 academicians from 60 foreign countries had participated in Russian studies on the education issues.

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