scholarly journals The 3Rs Principle in Animal Experimentation: A Legal Review of the State of the Art in Europe and the Case in Italy

BioTech ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 9
Author(s):  
Enrico Maestri

The aim of this paper is to describe the essential points of Italian and European legislation governing the use of animals in biomedical experimentation. A close look will be taken at the principles of the 3Rs, which represent the mainstay of the legal architecture based on which a correct interpretation may be drawn of the legislative documents on animal experimentation. Furthermore, this paper will address the ways in which Directive 2010/63/EU is implemented in Italian legislation on the welfare of laboratory animals. In addition to an assessment of legal issues (such as the scope of jurisdiction of supervisory authorities tasked with issuing authorizations), it will include a discussion of cases of inadequate and insufficient implementation of the requirements laid down by Directive 2010/63/EU. Both the consistency of the interpretation of national legislation with the Directive and the direct effectiveness of the Directive in national law, in which animal testing has been and still is the subject of heated debate between supporters and opponents, will be examined.

2021 ◽  
pp. 030631272110102
Author(s):  
Wakana Suzuki1

Japanese scientists and technicians are expected to adhere to international standards of humane animal experimentation, but their understandings of human-animal relationships and their ways of caring for laboratory animals do not always fit neatly with global norms. Under the loose and eclectic regulations that govern animal testing in Japan, animal ethicists, scientists and technicians behave improvisationally to deal with tensions and discomfort. This article focuses on how these actors bring various ‘moves’ to this improvisational care, such as everyday eating and spiritual practices. I develop the concept of ‘chains of improvisation’. In contrast with the more commonly used notion of ‘tinkering’, this concept helps to articulate a case where care is continuously destabilized and remade through encounters with otherness. By paying attention to how members of this laboratory question what good care for laboratory animals entails, this case provides an opening for rethinking the cost-benefit logic that underlies global discourses around laboratory animal ethics.


2019 ◽  
Vol 8 (1) ◽  
pp. 221-235 ◽  
Author(s):  
Daniella De Paula Chiesa ◽  
Mário Antônio Sanches ◽  
Daiane Priscila Simão-Silva

O estudo do Planejamento familiar, no contexto da bioética, abre-se para diversas perspectivas, entre elas a valorização dos seus diferentes atores. Situado neste contexto o artigo tem como objetivo identificar o perfil de gênero na produção científica sobre Planejamento Familiar no Brasil, entre 2000 e 2014, assim como a área de formação e especialização dos autores. Foram utilizadas metodologias que permitiram mapear o estado da arte do tema estudado, a partir de uma revisão da literatura. O resultado da pesquisa identifica que a produção científica sobre Planejamento Familiar no Brasil se compõe de perfil destacadamente feminino (71,76%). Dos 73 artigos analisados, 42 (57,53%) o foco do tema está direcionado à mulher assim como evidencia-se a área de ciências da saúde com maior concentração das publicações do tema.  Este aspecto da pesquisa abre para uma realidade complexa onde se buscam criticamente as razões para a pesquisa em Planejamento Familiar ter ênfase na mulher e ser um tema de relevância nas ciências da saúde.Palavras-chave: Produção científica, Planejamento Familiar, Gênero.  ABSTRACT: The study of Family Planning, in the context of bioethics, opens to diverse perspectives, among them the appreciation of their different agents. Situated in this context the article aims to identify the profile of gender in scientific literature on Family Planning in Brazil, between 2000 and 2014, as well as the area of training and specialization of the authors. Methodologies were used which allowed to map the State of the art of the subject studied, from a review of the literature. The results found identify that the scientific production on Family Planning in Brazil is formed with a outstandingly female profile (71,76%). Of the 73 articles examined, 42 (57.53%) the focus of the topic is directed to women as well as showing the health sciences area with highest concentration of publications. This aspect of the research opens to a complex reality where we seek critically the reasons for Research in Family Planning have emphasis on woman and be a topic of relevance in health sciences.Keywords: Scientific Production, Family Planning, Gender.


Author(s):  
Muhammad Yousaf ◽  
Petr Bris

A systematic literature review (SLR) from 1991 to 2019 is carried out about EFQM (European Foundation for Quality Management) excellence model in this paper. The aim of the paper is to present state of the art in quantitative research on the EFQM excellence model that will guide future research lines in this field. The articles were searched with the help of six strings and these six strings were executed in three popular databases i.e. Scopus, Web of Science, and Science Direct. Around 584 peer-reviewed articles examined, which are directly linked with the subject of quantitative research on the EFQM excellence model. About 108 papers were chosen finally, then the purpose, data collection, conclusion, contributions, and type of quantitative of the selected papers are discussed and analyzed briefly in this study. Thus, this study identifies the focus areas of the researchers and knowledge gaps in empirical quantitative literature on the EFQM excellence model. This article also presents the lines of future research.


2010 ◽  
Vol 4 (2) ◽  
pp. 135-156 ◽  
Author(s):  
Dorothea E. Schulz

Starting with the controversial esoteric employment of audio recordings by followers of the charismatic Muslim preacher Sharif Haidara in Mali, the article explores the dynamics emerging at the interface of different technologies and techniques employed by those engaging the realm of the Divine. I focus attention on the “border zone” between, on the one hand, techniques for appropriating scriptures based on long-standing religious conventions, and, on the other, audio recording technologies, whose adoption not yet established authoritative and standardized forms of practice, thereby generating insecurities and becoming the subject of heated debate. I argue that “recyclage” aptly describes the dynamics of this “border zone” because it captures the ways conventional techniques of accessing the Divine are reassessed and reemployed, by integrating new materials and rituals. Historically, appropriations of the Qur’an for esoteric purposes have been widespread in Muslim West Africa. These esoteric appropriations are at the basis of the considerable continuities, overlaps and crossovers, between scripture-related esoteric practices on one side, and the treatment by Sharif Haidara’s followers of audio taped sermons as vessels of his spiritual power, on the other.


1985 ◽  
Vol 19 (1) ◽  
pp. 9-33 ◽  
Author(s):  
J. L. Berggren

In Recent Years, many discoveries in the history of Islamic mathematics have not been reported outside the specialist literature, even though they raise issues of interest to a larger audience. Thus, our aim in writing this survey is to provide to scholars of Islamic culture an account of the major themes and discoveries of the last decade of research on the history of mathematics in the Islamic world. However, the subject of mathematics comprised much more than what a modern mathematician might think of as belonging to mathematics, so our survey is an overview of what may best be called the “mathematical sciences” in Islam; that is, in addition to such topics as arithmetic, algebra, and geometry we will also be interested in mechanics, optics, and mathematical instruments.


2003 ◽  
Vol 31 (1_suppl) ◽  
pp. 132-137 ◽  
Author(s):  
Kathryn A.L. Bayne

The increasing emphasis on the provision of environmental enrichment to laboratory animals, vis-à-vis the USDA Animal Welfare Regulations, the Guide for the Care and Use of Laboratory Animals (NRC 1996), and a potential forthcoming policy from the USDA on the subject, can be difficult to accommodate in a toxicology research environment. A summary will be provided of current requirements and recommendations. Then, strategies for meeting regulatory requirements will be described for non-rodent animals used in toxicology research. These strategies will address methods of both social enrichment, such as pair or group housing, as well as non-social enrichment, such as cage furniture, food enrichments, and toys. In addition, the value of positive interactions with staff (e.g., through training paradigms or socialization programs) will also be discussed. Apparent in the discussion of these strategies will be an overarching recognition of the necessity to avoid introducing confounding variables into the research project and to avoid compromising animal health. The roles of the Institutional Animal Care and Use Committee (IACUC) and the attending veterinarian in helping scientists balance animal well-being, the scientific enterprise and the regulatory environment will be described.


Author(s):  
Tatiana V. Chernigovskaya ◽  

The paper discusses semiotic aspects of higher human functions and a possibility and relevance of traditional search for their neurophysiological basis. The state of the art on the subject is reviewed and the lack of data on anthropological specificity for reasoning, thinking, language and its AI modeling is highlighted. Experimental neuroscience presumes that if we know the characteristics of neu­rons and their connections, we automatically understand what mind and con­sciousness are. However, it is evident that such a paradigm does not allow us to get relevant answers to the main questions. I argue that the problem should be dealt with not only within the field of neurophysiology proper. Rather, such re­search should involve exploring the 'archeology' of mental processes as they are revealed in arts as well as in other symbolic spaces. The paper discusses the ade­quacy of physiological methodology when it is employed to demonstrate brain mechanisms of higher functions. Besides, I explore the relevance of juxta­posing similar data from other biological and artificial intelligent systems. I view language processing, mind and reasoning and 1st person experience (qualia) as human specific features, and questions the possibility of direct testing these phenomena. The paper links genetic, anthropological and neurophysio­logical data to semiotic activity and semiosphere formation as the basis for com­munication. The paper discusses the place of humans in the changing world in the context of new cognitive dimensions.


2021 ◽  
Vol 11 (2) ◽  
pp. 177-187
Author(s):  
Donato Castronuovo

The subject is addressed by focusing on two aspects: i) the identification of constant political-criminal models in emergency legislation, with particular reference to the fight against terrorism; ii) diachronic and synchronic dissemination of such constants in other legal experiences, both of the past and contemporary with Italian legislation of the 1970s/1980s. The concluding paragraph will offer some brief remarks regarding the relevance of such tools today in the fight against international terrorism in Europe, taking into special consideration one of the aforesaid constants, namely, reward-based legislation aimed at so-called pentiti.


2015 ◽  
Vol 58 (1) ◽  
pp. 191-209 ◽  
Author(s):  
Joana Castro Pereira

Is it possible to talk about the rise of a new global (dis)order founded on the challenges posed by environmental issues? Through the review of the state of the art on the subject, this article analyzes the growing importance of the environment, and natural resources in particular, in international relations; and aims to raise awareness among International Relations scholars to the potential positive impact of the development of the discipline in integration with global environmental change studies.


1967 ◽  
Vol 71 (677) ◽  
pp. 344-348
Author(s):  
J. V. Connolly

During the past two years, there has been a sharp acceleration to the interest which industry has displayed in the subject of management education. This can be attributed to these factors: —(a) A more widespread realisation of the gap developing between the UK and a number of foreign economies, as manifested by diverging rates of the major economic indicators.(b) The attainment of top-management responsibilities by a younger generation of managers, many of whom had been given some earlier training and who were more conscious of its value than the incumbents of the job from earlier generations.(c) The publication of the Franks, Robbins and (in the aerospace industry) the Plowden reports.(d) The impact of the Industrial Training Boards making it manifest, in terms of serious levies, that training was an economic necessity and therefore must be investigated thoroughly.Notwithstanding the widespread awakening of interest, it is very belated and sets numerous problems. The problems are in two areas—scale and quality.


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