scholarly journals Quantifying the Effects of Vibration on Medicines in Transit Caused by Fixed-Wing and Multi-Copter Drones

Drones ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 22
Author(s):  
Andrew Oakey ◽  
Tim Waters ◽  
Wanqing Zhu ◽  
Paul G. Royall ◽  
Tom Cherrett ◽  
...  
Keyword(s):  
Road Transport ◽  
Uv Spectra ◽  
Frequency Spectra ◽  
Vibration Measurements ◽  
British Pharmacopoeia ◽  
Medical Products ◽  
Industry Standard ◽  
The Stability ◽  
In Transit

The concept of transporting medical products by drone is gaining a lot of interest amongst the medical and logistics communities. Such innovation has generated several questions, a key one being the potential effects of flight on the stability of medical products. The aims of this study were to quantify the vibration present within drone flight, study its effect on the quality of the medical insulin through live flight trials, and compare the effects of vibration from drone flight with traditional road transport. Three trials took place in which insulin ampoules and mock blood stocks were transported to site and flown using industry standard packaging by a fixed-wing or a multi-copter drone. Triaxial vibration measurements were acquired, both in-flight and during road transit, from which overall levels and frequency spectra were derived. British Pharmacopeia quality tests were undertaken in which the UV spectra of the flown insulin samples were compared to controls of known turbidity. In-flight vibration levels in both the drone types exceeded road induced levels by up to a factor of three, and predominant vibration occurred at significantly higher frequencies. Flown samples gave clear insulin solutions that met the British Pharmacopoeia specification, and no aggregation of insulin was detected.

Criteria for evaluation of the coordinate measurements quality of parts geometric parameters at pilot-experimental production

2019 ◽  
pp. 3-8
Author(s):  
N.Yu. Bobrovskaya ◽  
M.F. Danilov
Keyword(s):  
Quality Indicators ◽  
Quality Management System ◽  
Technical Specification ◽  
Experimental Production ◽  
Technological Heredity ◽  
Coordinate Measurements ◽  
Reasonable Choice ◽  
The Stability ◽  
Geometric Elements

The criteria of the coordinate measurements quality at pilot-experimental production based on contemporary methods of quality management system and traditional methods of the measurements quality in Metrology are considered. As an additional criterion for quality of measurements, their duration is proposed. Analyzing the problem of assessing the quality of measurements, the authors pay particular attention to the role of technological heredity in the analysis of the sources of uncertainty of coordinate measurements, including not only the process of manufacturing the part, but all stages of the development of design and technological documentation. Along with such criteria as the degree of confidence in the results of measurements; the accuracy, convergence, reproducibility and speed of the results must take into account the correctness of technical specification, and such characteristics of the shape of the geometric elements to be controlled, such as flatness, roundness, cylindrical. It is noted that one of the main methods to reduce the uncertainty of coordinate measurements is to reduce the uncertainty in the initial data and measurement conditions, as well as to increase the stability of the tasks due to the reasonable choice of the basic geometric elements (measuring bases) of the part. A prerequisite for obtaining reliable quality indicators is a quantitative assessment of the conditions and organization of the measurement process. To plan and normalize the time of measurements, the authors propose to use analytical formulas, on the basis of which it is possible to perform quantitative analysis and optimization of quality indicators, including the speed of measurements.

Statistical Management of Food Production Processes

2020 ◽  
pp. 30-35
Author(s):  
N.A. Jurk ◽  
Keyword(s):  
Production Process ◽  
Control Chart ◽  
Food Production ◽  
Time Interval ◽  
Bakery Products ◽  
Shewhart Control ◽  
Manufactured Products ◽  
Mnemonic Technique ◽  
The Stability

The article presents scientific research in the field of statistical controllability of the food production process using the example of bakery products for a certain time interval using statistical methods of quality management. During quality control of finished products, defects in bakery products were identified, while the initial data were recorded in the developed form of a checklist for registering defects. It has been established that the most common defect is packaging leakage. For the subsequent statistical assessment of the stability of the production process and further analysis of the causes of the identified defect, a Shewhart control chart (p-card by an alternative feature) was used, which allows you to control the quality of manufactured products by the number of defects detected. Analyzing the control chart, it was concluded that studied process is conditionally stable, and the emerging defects are random. At the last stage of the research, the Ishikawa causal diagram was used, developed using the 6M mnemonic technique, in order to identify the most significant causes that affect the occurrence of the considered defect in bakery products. A more detailed study will allow the enterprise to produce food products that meet the established requirements.

scholarly journals High-Speed Video Analysis of the Process Stability in Plasma Spraying

2021 ◽  
Author(s):  
K. Bobzin ◽  
M. Öte ◽  
M. A. Knoch ◽  
I. Alkhasli ◽  
H. Heinemann
Keyword(s):  
Plasma Spraying ◽  
High Speed ◽  
Plasma Jet ◽  
Plasma Jets ◽  
Time Dependent ◽  
Acquisition Time ◽  
Fast Fourier Transformation ◽  
Frequency Spectra ◽  
Dependent Signal ◽  
The Stability

AbstractIn plasma spraying, instabilities and fluctuations of the plasma jet have a significant influence on the particle in-flight temperatures and velocities, thus affecting the coating properties. This work introduces a new method to analyze the stability of plasma jets using high-speed videography. An approach is presented, which digitally examines the images to determine the size of the plasma jet core. By correlating this jet size with the acquisition time, a time-dependent signal of the plasma jet size is generated. In order to evaluate the stability of the plasma jet, this signal is analyzed by calculating its coefficient of variation cv. The method is validated by measuring the known difference in stability between a single-cathode and a cascaded multi-cathode plasma generator. For this purpose, a design of experiment, covering a variety of parameters, is conducted. To identify the cause of the plasma jet fluctuations, the frequency spectra are obtained and subsequently interpreted by means of the fast Fourier transformation. To quantify the significance of the fluctuations on the particle in-flight properties, a new single numerical parameter is introduced. This parameter is based on the fraction of the time-dependent signal of the plasma jet in the relevant frequency range.

scholarly journals Identifying Stabilising Effects on Survey Based Life Satisfaction Using Quasi-maximum Likelihood Estimation

2021 ◽  
Author(s):  
Johannes Klement
Keyword(s):  
Life Satisfaction ◽  
Maximum Likelihood ◽  
Maximum Likelihood Estimation ◽  
Negative Binomial ◽  
Measurement Instrument ◽  
Likelihood Estimation ◽  
Satisfaction Scale ◽  
Quasi Maximum Likelihood ◽  
The Stability

AbstractTo which extent do happiness correlates contribute to the stability of life satisfaction? Which method is appropriate to provide a conclusive answer to this question? Based on life satisfaction data of the German SOEP, we show that by Negative Binomial quasi-maximum likelihood estimation statements can be made as to how far correlates of happiness contribute to the stabilisation of life satisfaction. The results show that happiness correlates which are generally associated with a positive change in life satisfaction, also stabilise life satisfaction and destabilise dissatisfaction with life. In such as they lower the probability of leaving positive states of life satisfaction and increase the probability of leaving dissatisfied states. This in particular applies to regular exercise, volunteering and living in a marriage. We further conclude that both patterns in response behaviour and the quality of the measurement instrument, the life satisfaction scale, have a significant effect on the variation and stability of reported life satisfaction.

scholarly journals Optical Analysis of RF Sputtering Plasma through Colour Characterization

Coatings ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 315 ◽  
Author(s):  
Ali Salimian ◽  
Roohollah Haghpanahan ◽  
Abul Hasnath ◽  
Hari Upadhyaya
Keyword(s):  
Rf Sputtering ◽  
Plasma Source ◽  
Film Coating ◽  
Chamber Pressure ◽  
Plasma Power ◽  
Plasma Sputtering ◽  
Chromaticity Index ◽  
Colour Parameters ◽  
The Stability

The photometric properties of an radio frequency (RF)-based sputtering plasma source were monitored through optical spectroscopy. The colour of the plasma source was deduced based on conventional chromaticity index analysis and it was compared to the direct spectral data plots of the emission peaks to investigate the possibility of characterising the plasma based on its specific colour and exploring the potential of defining a new method by which the plasma sputtering process can be addressed based on the plasma colour parameters. The intention of this investigation is to evaluate the possibility of simplifying the monitoring and assessment of the sputtering process for applied scientists operating plasma sputter deposition systems. We demonstrate a viable potential for this technique in terms of providing information regarding the stability of the plasma, chamber pressure, and plasma power; however, further work is underway to verify and assess a relationship between the quality of the thin film coating and the colour characteristics of the deposition plasma. Here, we only focus on the feasibility of such an approach and demonstrate interesting observations. We observed a linear relationship between the colour functions and the plasma power, while the stability of the sputtering plasma can be assessed based on the plasma colour functions. The colour functions also follow a unique pattern when the working gas pressure is increased.

scholarly journals High temperature structural study of decagonal Al-Cu-Rh quasicrystal.

2014 ◽  
Vol 70 (a1) ◽  
pp. C94-C94
Author(s):  
Pawel Kuczera ◽  
Walter Steurer
Keyword(s):  
Structural Changes ◽  
Configurational Entropy ◽  
Lattice Vibrations ◽  
X Ray Diffraction ◽  
Stabilization Mechanism ◽  
X Ray ◽  
Comparative Structure ◽  
The Stability

The structure of d(ecagonal)-Al-Cu-Rh has been studied as a function of temperature by in-situ single-crystal X-ray diffraction in order to contribute to the discussion on energy or entropy stabilization of quasicrystals (QC) [1]. The experiments were performed at 293 K, 1223 K, 1153 K, 1083 K, and 1013 K. A common subset of 1460 unique reflections was used for the comparative structure refinements at each temperature. The results obtained for the HT structure refinements of d-Al-Cu-Rh QC seem to contradict a pure phasonic-entropy-based stabilization mechanism [2] for this QC. The trends observed for the ln func(I(T1 )/I(T2 )) vs.|k⊥ |^2 plots indicate that the best on-average quasiperiodic order exists between 1083 K and 1153 K, however, what that actually means is unclear. It could indicate towards a small phasonic contribution to entropy, but such contribution is not seen in the structure refinements. A rough estimation of the hypothetic phason instability temperature shows that it would be kinetically inaccessible and thus the phase transition to a 12 Å low T structure (at ~800 K) is most likely not phason-driven. Except for the obvious increase in the amplitude of the thermal motion, no other significant structural changes, in particular no sources of additional phason-related configurational entropy, were found. All structures are refined to very similar R-values, which proves that the quality of the refinement at each temperature is the same. This suggests, that concerning the stability factors, some QCs could be similar to other HT complex intermetallic phases. The experimental results clearly show that at least the ~4 Å structure of d-Al-Cu-Rh is a HT phase therefore entropy plays an important role in its stabilisation mechanism lowering the free energy. However, the main source of this entropy is probably not related to phason flips, but rather to lattice vibrations, occupational disorder unrelated to phason flips like split positions along the periodic axis.

St Symeon the New Theologian (969-1022): Byzantine spiritual renewal in search of a precedent

1997 ◽  
Vol 33 ◽  
pp. 75-90
Author(s):  
John Anthony McGuckin
Keyword(s):  
Christian Tradition ◽  
Spiritual Renewal ◽  
Divine Love ◽  
The West ◽  
Conference Theme ◽  
Autobiographical Accounts ◽  
The Stability ◽  
The Church

St Symeon the New Theologian is, without question, one of the most original and intriguing writers of medieval Byzantium. Indeed, although still largely unknown in the West, he is surely one of the greatest of all Christian mystical writers; not only for the remarkable autobiographical accounts he gives of several visions of the divine light, but also for the passionate quality of his exquisite Hymns of Divine Love, the remarkable intensity of his pneumatological doctrine, and the corresponding fire he brings to his preaching of reform in the internal and external life of the Church. He was a highly controversial figure in his own day. His disciples venerated him as a saint who had returned to the roots of the Christian tradition and personified its repristinization. His opponents, who secured his deposition and exile, regarded him as a dangerously unbalanced incompetent who, by overstressing the value of personal religious fervour, had endangered the stability of that tradition. The Vita which we possess was composed in 1054, in an attempt to rehabilitate Symeon’s memory and prepare for the return of his relics to the capital from which he had been expelled when alive. This paper will investigate how he himself understood and appropriated aspects of the earlier tradition (particularly monastic spirituality), hoping to elucidate why he felt himself inspired to reformist zeal, and why many of his contemporaries (not simply his ‘worldly opponents’ as his hagiographer would have us believe) regarded him as unbalanced. It will end by attempting some reflection on what the controversy reveals on the larger front about how the Church ‘selectively looks back on itself, so to paraphrase our president’s description of the conference theme, and whether the model of tradition and its reception exemplified in this Byzantine writer can offer anything to the dialogue between history and theology which the doctrine of Tradition (Paradosis) inevitably initiates.

An experimental study of the stability of mass standards in transit

Metrologia ◽  
2008 ◽  
Vol 45 (2) ◽  
pp. 233-240 ◽  
Author(s):  
K Fen ◽  
E C Morris
Keyword(s):  
Experimental Study ◽  
The Stability ◽  
In Transit

Design of Hydraulic Descaling Computer Control System

2014 ◽  
Vol 608-609 ◽  
pp. 19-22
Author(s):  
Ping Xu ◽  
Jian Gang Yi
Keyword(s):  
Control System ◽  
Stability Problem ◽  
Computer Control ◽  
Control Methods ◽  
Computer Control System ◽  
Control Software ◽  
Pressure Water ◽  
Working Principle ◽  
The Stability

Hydraulic descaling system is the key device to ensure the surface quality of billet. However, traditional control methods lead to the stability problem in hydraulic descaling system. To solve the problem, the construction of the hydraulic descaling computer control system is studied, the working principle of the system is analyzed, and the high pressure water bench of hydraulic descaling is designed. Based on it, the corresponding computer control software is developed. The application shows that the designed system is stable in practice, which is helpful for enterprise production.

scholarly journals Spectral shapes and parameters from three different wave sensors

2021 ◽  
Author(s):  
Anne Karin Magnusson ◽  
Robert Jensen ◽  
Val Swail
Keyword(s):  
Frequency Spectra ◽  
Measurement Systems ◽  
Wave Measurements ◽  
Climate Monitoring ◽  
Production Platform ◽  
Wave Sensors ◽  
Central North Sea ◽  
Wave Forecasting ◽  
Wave Properties

AbstractThe quality of wave measurements is of primary importance for the validation of wave forecasting models, satellite wave calibration and validation, wave physics, offshore operations and design and climate monitoring. Validation of global wave forecasts revealed significant regional differences, which were linked to the different wave buoy systems used by different countries. To fully understand the differences between the wave measurement systems, it is necessary to go beyond investigations of the integral wave parameters height, period and direction, into the frequency spectra and the four directional Fourier parameters that are used to estimate the directional distribution. We here analyse wave data measured from three different sensors (non-directional Datawell Waverider buoy, WaveRadar Rex, Optech laser) operating at the Ekofisk oil production platform located in the central North Sea over a period of several months, with significant wave height ranging from 1 to 10 m. In general, all three sensors provide similar measurements of the integral wave properties and frequency spectra, although there are some significant differences which could impact design and operations, forecast verification and climate monitoring. For example, the radar underestimates energy in frequency bands higher than 8 s by 3–5%, swell (12.5–16 s) by 5–13%, while the laser has 1–2% more energy than the Waverider in the most energetic bands. Lee effects of structures are also estimated. Lower energy at the frequency tail with the radar has an effect on wave periods (they are higher); wave steepness is seen to be reduced by 10% in the wind seas. Goda peakedness and the unidirectional Benjamin-Feir index are also examined for the three sensors.

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