scholarly journals Intsia bijuga Heartwood Extract and Its Phytosome as Tyrosinase Inhibitor, Antioxidant, and Sun Protector

Forests ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1792
Author(s):  
Rita Kartika Sari ◽  
Yanico Hadi Prayogo ◽  
Ratih Afrida Lismana Sari ◽  
Nur Asidah ◽  
Mohamad Rafi ◽  
...  
Keyword(s):  
Active Ingredient ◽  
Biological Activities ◽  
Economic Value ◽  
Tyrosinase Inhibitor ◽  
Protection Factor ◽  
Extraction Solvent ◽  
Antityrosinase Activity ◽  
Phytochemical Profile ◽  
Sun Protection Factor ◽  
Ethanol Extracts

Intsia bijuga (Colebr.) wood (Indonesian: Merbau) is commercial wood with high economic value and is most commonly found in Indonesia. Intsia wood extractives have biological activities related to their potential as natural active ingredients for antiaging cosmetics This study aimed to select the best extraction solvent and phytosome formulation of I. bijuga heartwood extract as an active ingredient for topical antiaging cosmetics. There were five and three variations on extraction solvent and phytosome formulation, respectively. Three main antiaging activity parameters, namely antioxidant, antityrosinase, and sun protection factor (SPF) values, were considered in selecting the best extract and phytosome formula. The results showed that 50% ethanol possessed good antioxidant and antityrosinase activity, but was lower in SPF value, which was significantly different than in other extracts. The phytochemical profile revealed robidanol and robinetin as the main constituent in five I. bijuga extracts. Phytosome F3 possessed high antioxidant, antityrosinase, and SPF values compared to other 50% ethanol phytosome extracts. It could be concluded that I. bijuga ethanol extracts and its phytosome are potent enough to be developed as an antiaging active ingredient in topical use cosmetics.

scholarly journals Phenolic Profile and Antioxidant Activity of Pulp and Peel from Peach and Nectarine Fruits

2016 ◽  
Vol 44 (1) ◽  
pp. 175-182 ◽  
Author(s):  
Branka T. STOJANOVIC ◽  
Snezana S. MITIC ◽  
Gordana S. STOJANOVIC ◽  
Milan N. MITIC ◽  
Danijela A. KOSTIC ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Prunus Persica ◽  
Biological Activities ◽  
Economic Value ◽  
Antioxidant Properties ◽  
Fruit Peel ◽  
Extraction Solvent ◽  
Phenolic Profiles ◽  
Antioxidant Characteristics

Peach (Prunus persica L.) is a fruit of high nutritional and economic value. Carbohydrates, dietary fibers, minerals and organic acids are among the major constituents of peach fruit, which contribute to the nutritional quality of both fresh fruits and juice. Polyphenolic compounds found in peach may play an important role in physiological functions related to human health. Different polyphenolics may have varied biological activities including antioxidant activity. In this study antioxidant characteristics between peel and pulp of different peach cultivars (‘Radmilovčanka’, ‘June Gold’, ‘Blake’, ‘Hale’, ‘Vesna’, ‘Adria’) and one of nectarine (‘Fantasia’) were investigated. The peel and pulp extracts showed a huge amount of total phenolics (TP), total flavonoids (TF), total hydroxycinnamates (TH) and total flavonols (TFL), ranging from 42.7-211.4, 11.1-128.5 mg GAE/100 g fresh weight (f.w.) (TP), 21.9 -94.9, 5.0-58.9 mg CE/100 g f.w. (TF), 28.4-389.2, 8.5-165.8 mg kg-1 f.w. (TH) and 17.3-54 mg kg-1 f.w. (TFL). High contents of phenolic compounds were significantly correlated with high antioxidant capacities. Peach pulp and peel differ significantly in their phenolic profiles: the pulp contains mainly chlorogenic, neochlorogenic and p-coumaric acids, whereas the peel possesses chlorogenic, neochlorogenic and p-coumaric acids together with several flavonol glycosides in huge amounts. Our results indicate that cultivar and extraction solvent play important roles in phenolic compositions and antioxidant properties of peach and nectarine extracts, which was shown using statistical analysis (ANOVA). There are high correlations between extracted phenolic compounds and peach and nectarine cultivars, and used solvent and part of the fruit (peel and pulp).

Phenolic Content, Antioxidant Properties, Key Enzyme Inhibitory Potential and Photoprotective Activity of Lawsonia inermis L

2020 ◽  
Vol 16 ◽  
Author(s):  
Rima Goudjil ◽  
Abdelkader Mekhaldi ◽  
Houari Benamar ◽  
Chawki Bensouici ◽  
Mohamed Amine Kahoul
Keyword(s):  
Antioxidant Activity ◽  
Ethyl Acetate ◽  
Enzyme Inhibition ◽  
Methanol Extract ◽  
Biological Activities ◽  
Sun Protection ◽  
Bioactive Molecules ◽  
Lawsonia Inermis ◽  
Protection Factor ◽  
Sun Protection Factor

Background:: Lawsonia inermis Linn (Lythraceae), commonly known as "Henna" is a medicinal plant widely used as a folk remedy and for its cosmetic properties. Objective:: The objective of this present work was to evaluate biological activities and to quantify phenolics in extracts. Methods:: The extracts were obtained from seeds of L. inermis by increasing the polarity of the solvent. The content of total phenolics, flavonoids, flavonols and tannins was determined using colorimetric methods. Also, to evaluate the antioxidant activity, six different assays, DPPH, ABTS, superoxide radical scavenging, inhibition of β-carotene bleaching, ferric reducing antioxidant power and phenanthroline assays were used. Enzyme inhibition activity was evaluated by acetylcholinesterase, butyrylcholinesterase and tyrosinase inhibition assays. Furthermore, photoprotective activity was determined by measuring sun protection factor. Results:: The extraction efficiency of phenolics, as well as the biological activities of plant extracts, were affected by solvent polarity. The highest content of phenolics was determined in methanol extract (786.54 ± 0.00 mg GAEg-1 DW), followed by the aqueous and ethyl acetate extracts (526.48 ± 0.40 and 331.25 ± 0.00 GAEg-1 DW, respectively). The above extracts also exhibited the highest antioxidant activity, while low polar extracts were characterized with the lowest content of phenolics, as well as the lowest antioxidant capacity. The highest enzyme inhibition activities were found in ethyl acetate extract. Moreover, the methanol extract showed the best photoprotective activity with sun protection factor of 43.05 ± 0.37. Conclusion:: These findings suggest a possible use of Henna seeds as a potential source of bioactive molecules with antioxidant, enzyme inhibition and skin protection properties.

scholarly journals Uso no-convencional del mucílago de avena en fotoprotección

2019 ◽  
pp. 10-16
Author(s):  
Juan Carlos Ramírez-Granados ◽  
César Díaz-Pérez ◽  
Lisbeth Almanza-Guerrero ◽  
María José Enríquez-Arredondo
Keyword(s):  
Aqueous Solution ◽  
Aqueous Solutions ◽  
Extinction Coefficient ◽  
Active Ingredient ◽  
Active Compound ◽  
Spectral Characteristics ◽  
Detailed Knowledge ◽  
Protection Factor ◽  
Sun Protection Factor ◽  
Absorbance Spectra

In this work, some spectral characteristics of oat mucilage were studied to obtain a deep and detailed knowledge about the possible application of this material in the absorption of dangerous ultraviolet radiation for human skin. For this purpose, the mucilage of oat was extracted and purified by adapting a previously reported method. Then, several aqueous solutions with different known concentrations of this extract were prepared. These solutions were analyzed with a spectrophotometer to determine their absorbance between 200 and 1000 nm. Through the absorbance spectra, the photoprotective capacity of the mucilage of oat in aqueous solution was evaluated. The extinction coefficient of this material was also calculated through spectrophotometric measurements and the Lambert-Beer Law. In addition, a cream with natural ingredients and oat mucilage as active compound was prepared to evaluate its sun protection factor and compare it with that of the aqueous mucilage. Finally, the feasibility of using the mucilage of oat as active ingredient in effective and safe sunscreens for people and the environment was analyzed.

Formulation and Sun Protection Factor Estimation of Squash Cucurbita maxima Seeds Sunblock Lotion

10.17158/322 ◽  
2014 ◽  
Vol 18 (2) ◽  
Author(s):  
Mary Jane G. Barluado
Keyword(s):  
Zinc Oxide ◽  
Active Ingredient ◽  
Sun Exposure ◽  
Sun Protection ◽  
Uv Spectrophotometry ◽  
Selling Price ◽  
Uvb Radiation ◽  
Cell Protection ◽  
Protection Factor ◽  
Sun Protection Factor

<p>The fact that the sun’s ultraviolet (UVA and UVB) radiation reaches the earth’s surface associates sun exposure with many skin problems such as sunburn, photoaging, hyperpigmentation, and skin cancers. Because sunlight is unavoidable, sunscreen/sunblock application is essential to protect the skin from the mentioned problems. Zinc, in the form of zinc oxide, is an active ingredient in sunblocks as it deflects away UVA and UVB. Zinc is an immunologically important mineral that helps in wound healing, antiinflammation, and cell protection. One natural and rich source of zinc is squash seeds, which many consider as trash. This study features the formulation of a sunblock lotion using squash seeds as the active ingredient. Squash seeds extract and powder were first subjected to Atomic Absorption Spectrophotometry (AAS) to quantitate zinc content, and enough were used to formulate a sunblock lotion to a final zinc concentration of 5%. Various physical tests on the finished product showed that it is stable and gentle, having high melting point of 440C, and being easily spreadable, water insoluble, and weakly basic at pH 7.5. Patch tests gave negative results in all subjects, indicating the product’s hypoallergenicity. UV spectrophotometry revealed substantially low UV absorbance (&lt;0.03 from 290nm – 320nm wavelengths), which is consistent with the action of zinc oxide as UV deflector, not absorber. The Sun Protection Factor (SPF) was determined using a modified formula set by the US Food and Drug Administration (US FDA) Code of Federal Regulations Title 21 based on the ratio of minimal erythema (skin redness due to dilated dermal capillaries) on protected skin to that on unprotected skin, and was calculated to be SPF20. Further, costing and pricing analysis showed the production cost to be P0.80/mL, and recommended selling price (at 100% markup) of P1.60/mL, which is up to 13 times cheaper than popular commercial brands of similar effectiveness. Thus, the study successfully formulated a gentle, effective, and affordable sunblock lotion using squash seeds as organic active ingredient.</p>

scholarly journals Evaluation of antioxidant, photoprotective and antinociceptive activities of Marcetia macrophylla extract: potential for formulation of sunscreens

2023 ◽  
Vol 83 ◽  
Author(s):  
S. C. C. Costa ◽  
P. K. F. Damasceno ◽  
R. G. G. Lima ◽  
M. B. Botura ◽  
C. R. C. Branco ◽  
...  
Keyword(s):  
Biological Activities ◽  
Spectroscopic Method ◽  
Pharmaceutical Preparations ◽  
Sun Protection ◽  
Array Detector ◽  
Protection Factor ◽  
Organoleptic Characteristics ◽  
Sun Protection Factor

Abstract The antioxidant, photoprotective and antinociceptive Marcetia macrophylla active extract was investigated as an active ingredient in a sunscreen cream formulation. Thus, the M. macrophylla extract showed IC50 of 3.43 mg/ml of the antioxidant (DPPH∙ scavenging test) and Sun Protection Factor of 20.25 (SPF/UV-B, at 250 µg/ml) and UV-A of 78.09% (photobleaching trans-resveratrol test). The antinociceptive activity was superior to all standards tested using the in vivo acetic acid-induced writhing test (99.14% at the dose of 200 mg/kg) and the high-performance liquid chromatography coupled with diode array detector and mass spectroscopy multi-stage (HPLC-DAD-MS/MS) enabled the structural characterization of the quercetin-3-O-hexoside, quercetin-3-O-pentoside and quercetin-3-O-desoxihexoside. The pharmaceutical formulation containing the Marcetia macrophylla crude active extract was prepared and the physicochemical tests (organoleptic characteristics, pH analysis and centrifugation), the in vitro UVB (sun protection factor, SPF) and UVA (β-carotene) using the spectroscopic method were investigated. The formulation showed satisfactory results concerning the physicochemical parameters evaluated and active against the UV test. Thus, M. macrophylla showed biological activities with potential use in pharmaceutical preparations.

scholarly journals Chemical Composition and Cosmeceutical Potential of the Essential Oil of Oncosiphon suffruticosum (L.) Källersjö

Plants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1315
Author(s):  
Selena O. Adewinogo ◽  
Rajan Sharma ◽  
Charlene W. J. Africa ◽  
Jeanine L. Marnewick ◽  
Ahmed A. Hussein
Keyword(s):  
Escherichia Coli ◽  
Chemical Composition ◽  
Essential Oil ◽  
South African ◽  
Biological Activities ◽  
The Sun ◽  
Protection Factor ◽  
Sun Protection Factor ◽  
Mic Value

The South African medicinal plant Oncosiphon suffruticosum (L.) Källersjö is an important remedy used to treat chronic, respiratory, and skin ailments. From the essential oil (EO) extracted by the hydrodistillation, sixteen constituent components were identified with oxygenated monoterpenes: camphor (31.21%), filifolone (13.98%), chrysanthenone (8.72%), 1,8-cineole (7.85%), and terpinen-4-ol (7.39%) as predominant constituents. In the antibacterial activity study, the EO was found most susceptible against Pseudomonas aeruginosa with an MIC of 6.4 mg/mL; however, it showed the same activity against Staphylococcus aureus and Escherichia coli with an MIC value of 12.8 mg/mL. The sun protecting factor (SPF) of the EO was found to be 2.299 and thus establishing it as a potentially important cosmeceutical for sunscreen applications. This is the first report investigating the essential oil of O. suffruticosum for its chemical composition and skin-related in vitro biological activities viz antibacterial, antioxidant capacity, antityrosinase, and sun protection factor.

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