scholarly journals Effect of Seasonal Variation during Annual Cyclist Training on Somatic Function, White Blood Cells Composition, Immunological System, Selected Hormones and Their Interaction with Irisin

2021 ◽  
Vol 10 (15) ◽  
pp. 3299
Author(s):  
Natalia Grzebisz-Zatońska ◽  
Stanisław Poprzęcki ◽  
Ilona Pokora ◽  
Kazimierz Mikołajec ◽  
Tomasz Kamiński

The aim of this study was to evaluate somatic, hormonal and immunological changes during the macrocycle of cyclists (9 well-trained men, age 25.6 ± 5.2 years and body weight 72.4 ± 7.35 kg). During the training macrocycle, four exercise control tests were carried out, and biochemical markers were measured in the laboratory. Seasonal training changes did not significantly disturb resting somatic and functional parameters, physical capacity (VO2max), body weight, the number of leukocytes and selected hormones. The secretory system of the organism did not respond significantly to the exercise stress in the training process, even with the increasing share of anaerobic processes in the subsequent periods of the macrocycle. Irisin and other parameters globally did not correlate with training volume. Irisin showed a significant correlation only with cortisol in the first period and human growth hormone in the second, and it showed a weak correlation in the third period with body mass and BMI. The lack of interactions between irisin level and other variables practically excludes its use in monitoring cyclist training. Future research would be complemented by the assessment of stress and postexercise changes in the cyclists’ macrocycle and expanding the research group to other athletes, including women.

1970 ◽  
Vol 12 (3) ◽  
pp. 627-634
Author(s):  
J. S. Gavora ◽  
G. C. Hodgson

Traditionally genotype by environment interaction studies have dealt with changes in external environment. In this experiment an attempt was made to alter internal environment and keep external environment constant. Cockerels from each of six different commercial stocks were injected with 0,1,2 and 4 mgs hydrocortisone acetate per 100 gms body weight at 14 days of age. This type of hormonal treatment was shown to release additional variability in growth without producing any stock-treatment interaction at the level of means. The results indicate a possible new avenue for future research.


2016 ◽  
Vol 14 (2) ◽  
Author(s):  
Fernanda De Mello ◽  
Daruzi Felippe ◽  
Leandro C. Godoy ◽  
Nívia Lothhammer ◽  
Luis R. J. Guerreiro ◽  
...  

ABSTRACT This study aimed to evaluate muscle organization in tambaqui in order to describe the muscle growth process. We analyzed the morphometric pattern of fibers from white muscle of young-adults (300 days) by smaller diameter. The organization of white muscle exhibited a typical morphological pattern found in other fish species. Heavier animals showed higher frequency of larger diameter fibers (>50 μm ) and smaller animals had higher frequency of smaller diameter fibers (<20 μm ) (P =0.005). However, both animals showed the same frequency of intermediate diameter fibers (20-50 μm ). Body weight showed a positive correlation with muscle diameter fiber (r=0.45), being 20-50 μm the diameters that contributed the most to animal weight (P <0.0001). A weak correlation between fiber diameter and animal sex was observed (r=0.2). Females showed higher frequency of large fiber diameters (>50 μm ) than males. However, there was no difference between body weight and sex (P =0.8). Our results suggest that muscle growth is by hypertrophy and hyperplasia due to a mosaic appearance from different diameters fibers, which is characteristic of large size fish species.


2020 ◽  
Vol 7 (5) ◽  
pp. 117-133
Author(s):  
Jaewon Lee

Background: This study was to investigate how acculturative stress affects older Korean immigrants' successful aging and whether resilience can play a mediator's role to the sample population's successful aging or not. The research design was a cross-sectional survey using three valid and reliable scales such as Successful Aging Scale, Acculturative Stress Scale, and Resilience Scale. A research shows that there is no or minimum correlation between acculturative stress and successful aging (Choi & Thomas, 2009). However, it was hypothesized that although there was a weak correlation between acculturative stress and successful aging, once the resilience involved as a mediator, the correlation would be stronger. Methods: The study was designed as a self-administered survey research using the scales mentioned above. One hundred and two (N=102) older Koreans who currently enrolled in Adult Health Care Centers in Los Angeles, CA, participated in this study. Multiple Regression, Correlation, ANOVA, and t-test was administered to analyze the collected data. Results: The results indicated that there was a positive but weak correlation between acculturative stress and the sample population's successful aging rate (r = .252, p<.05). Interestingly, when resilience intervened as a mediator, the correlation between acculturation and successful aging was increased to (r = .622, p<.05). Therefore, the study discovered that the resilience was able to play a mediator's role between acculturative stress and successful aging among the older Korean immigrants. Implications: The findings can be directed to social work researchers and practitioners to help educate the ethnic older adults in the community on the social and behavioral importance of the positive aspects of aging such as successful aging and healthy aging to increase the chance of community member's longevity. Future research will include other ethnic and immigrant older populations in the community to show internal and external validity of the study related to successful aging, acculturative stress, and resilience.


2021 ◽  
Vol 1 (2) ◽  
pp. 17-28
Author(s):  
Favour N. Ujowundu ◽  
◽  
Nathan N. Oparaeche ◽  
Chinyere Henrientta Onuoha ◽  
Moshood Abiola Haruna ◽  
...  

Background: The ethanol extract of Combretum dolichopentalum (EECD) is employed in Nigeria to stabilize the uterus after parturition. The ability of EECD to confer protection on rats destabilized by moderate concentrations of carbon tetrachloride (CCl4) was evaluated. Methods: Fifty rats were assigned to 5 groups of 10 rats each. The experimental animals after acclimatization were handled accordingly: Groups 1 and 2 respectively were maintained on food and water only throughout the study. Group 3, 4, and group 5 were pre-treated with 250 mg/kg and 500 mg/kg body weight of EECD and 50 mg/kg of silymarin for 28 respectively. All groups except group 1 were intoxicated to 0.2 ml/kg body weight of CCl4, administered via an intraperitoneal route on day 29. Serum pipetted from the blood of the rats after cardiac puncture was assayed for antioxidant enzymes, lipid peroxidation product and serum iron, zinc and biocarbonate. Haematological analysis was also conducted. Results: Administration of CCl4 at 0.2 ml/kg b.w slightly increased the oxidizing species as indicated in the concentration of malondialdehyde in the rats while reducing the antioxidant enzymes; it increased the Iron and zinc concentrations and also the haematological parameters except for the white blood cells. However, this was corrected by pre-treatment with the EECD dosedependently. Conclusion: These characteristics portends that the crude ethanol extract of C. dolichopentalum could be employed to correct minor oxidative perturbation induced by CCl4 intoxication


2020 ◽  
Vol 8 (12) ◽  
pp. 827-832
Author(s):  
Narges M. Kablan ◽  
◽  
Khadija A. Ali ◽  
Kamlah J. Said ◽  
Mabroka A. Ali ◽  
...  

End stage renal disease (ESRD) is a major health problem worldwide. In Libya, limited studies are available on children with ESRD.Regular assessment of laboratory parameters is the only way to reduce their risk of mortality.This study aimed to determinethe demographic characteristics and evaluate the hematological profile of children on hemodialysis (HD) admitted to the dialysis unit in Benghazi Pediatric hospital, Benghazi, Libya during the period 3rd of December, 2017 to 15th of January 2018.A structured form was used to record data collected from patients files. Data includedage, gender, body weight, treatment history, drug history, duration and frequency of HD and laboratory tests results, specifically white blood cells (WBC), hemoglobin (HB), blood urea, glucose, Albumin, uric acid, serum creatinine, serum iron, calcium, phosphate, sodium and potassium.Number of patients on HD includedin this study was seven with average age of 11years,the majority (71%)were males.Average body weight of female patients was24.2kg,while male patients averagebody weight was25.52kg. Most of the patients(57%)hadhigh BP.71%of patientsstarted dialysis sincemore than one year.Patients underwentdialysisthree times a week represented(86%),while the rest of patients underwent dialysis four times a weekrepresented(14%).All patients had anemia and highcreatininelevel.Providing an appropriate care for children on maintenance dialysis in Libya is quitedifficult. Increasing the awareness ofparents about ESRD is necessary to improve the life quality of children with ESRD.


1977 ◽  
Vol 86 (2) ◽  
pp. 243-250 ◽  
Author(s):  
Y. Okada ◽  
K. Watanabe ◽  
T. Takeuchi ◽  
T. Hata ◽  
H. Mikam ◽  
...  

ABSTRACT A propranolol-glucagon test was evaluated in 24 control normal children, 21 pituitary dwarfs, 15 patients with constitutional short stature, 2 with chromosome aberration and 4 with miscellaneous diseases. The dose of glucagon enough for the stimulation of human growth hormone (HGH) secretion is more than 20 μg/kg of body weight. During the test in the control subjects the serum HGH level increased from 2.3 ± 1.2 ng/ml to a maximum level of 30.0 ± 15.1 ng/ml, when 10 mg propranolol, regardless of body weight and 30 μg glucagon per kg of body weight are given. The dose of propranolol administered ranged from 0.2 to 1.0 mg/kg of body weight in normal children studied. Serum 11-OHCS also increased significantly from 14.5 ± 11.2 μg/100 ml to 30.1 ± 15.5 μg/100 ml (P <0.01). There was no difference in the maximum level of urinary total catecholamines in propranolol-glucagon test between 7 pituitary dwarfs and 7 control subjects. The mechanism of HGH response to propranolol-glucagon administration is unknown, but propranolol-glucagon administration is a sensitive and reliable provocative test for HGH secretion, since false negative responses of HGH are not observed in patients with non-pituitary disease.


2018 ◽  
Vol 53 (2) ◽  
pp. 155-160
Author(s):  
MR Islam ◽  
MG Azom

For evaluation of Fulton’s condition factor (CFf), relative body weight (BWr) and form (a3.0) factor affecting growth, 5 fishes (Aspidoparia jaya, Gagata cenia, G. youssoufi, Salmophasia bacaila and S. phulo) were collected from the Atari River in Dinajpur district of Bangladesh. Significant differences (p < 0.05) were recorded among the values of CFf (0.47-1.56) but not for BWr (79.60- 128.39). Based on CFf values, analysis of similarities (ANOSIM, p < 0.01) revealed that maximum distances (R = 0.9946) were found between G. youssoufi and S. bacaila while lowest (R = 0.2175) between G. cenia and S. phulo. Using two-dimensional nMDS scaling of CFf and BWr, G. youssoufi showed good health condition (CFf = 1.22±0.01; BWr = 100.63±0.79) and were separated (stress = 0.0003) from other fishes. Lowest a3.0 value was noted for S. bacaila (0.004) and highest for G. youssoufi (0.012). Therefore, G. youssoufi showed healthier and former body with more adaptability in this river than those of others. These are the first records for proper management of above mentioned fish species and future research in the near future.Bangladesh J. Sci. Ind. Res.53(2), 155-160, 2018


2014 ◽  
Vol 66 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Maria Luisa Mansego ◽  
Fermin Ignacio Milagro ◽  
Maria Angeles Zulet ◽  
José Alfredo Martinez

The objective of this study was to examine whether 7 SNPs previously associated with obesity-related traits that add or remove potential sites of DNA methylation are accompanied by differential DNA methylation and subsequently affect adiposity variables or body weight reduction in WBC from obese subjects under an energy-restricted program. Material and Methods: Anthropometric measurements were assessed in 47 volunteers recruited within the RESMENA study (Spain). At baseline, DNA from white blood cells was isolated and 7 obesity-related trait CpG-SNPs were genotyped by TaqMan-PCR. Then, methylation levels of CpG-SNP sites were quantified by MassArray® EpiTyper™ or MS-HRM approaches. Results: Differential DNA methylation levels were observed by genotypes in all of the CpG-SNPs analyzed. The FTO and BDNF methylation levels were further correlated with baseline body weight and, BDNF mRNA levels and body weight change, respectively. Moreover, the rs7359397 (SH2B1) was associated with the body weight, body mass index, and truncal fat mass reduction. Conclusions: Our results reveal the interaction of epigenetic and genetic variations in CpG-SNPs, especially in BDNF and SH2B1 genes, and how allele-specific methylation may contribute to elucidate the possible molecular mechanisms as these SNPs are affecting the decrease of mRNA levels and contributing to a lower body weight reduction. © 2014 S. Karger AG, Basel


2002 ◽  
Vol 2002 ◽  
pp. 87-87 ◽  
Author(s):  
A.R.G. Wylie ◽  
D.J. Devlin ◽  
A.J. Bjourson

A review of published leptin data for growing lambs, older ewes and mature dairy cows in late lactation showed that only 0.30-0.37 of the variation in blood leptin concentration was explained by differences in body fat variably expressed as % of liveweight (LW), backfat thickness and body condition score (BCS) respectively (Wylieet al., 2002). In dairy cows between 15d and 226d postpartum, Wylieet al(2002) observed no overall correlation between leptin at slaughter and lipid expressed as % of LW, empty body weight or carcase weight and only a weak correlation in cows in mid-lactation. Losses of fat during early lactation may ‘uncouple’ the link between leptin and fat and produce a bias across all of lactation. Another explanation is that leptin may be more closely linked with lipogenesis than with the amount of stored fat. This study revisits some metabolite and hormone data from a previous investigation of IGF-1 changes in fed, fasted and re-fed sheep in the light of more recently obtained leptin concentrations in the same animals.


Author(s):  
Denver E. Severt ◽  
Asli D.A. Tasci

Purpose Tourism activities inherently include the liminoid state of mind that impels people to go out of ordinary behavior, some of which is inversionary. The purpose of this paper is to explore travelers’ cruise behavior as related to their needs while entering and experiencing a cruise trip. Design/methodology/approach A total of 395 vacationers were sampled and surveyed about their selected top three factors for cruising, motivations for cruising and needs while cruising. The sample was grouped into inversioners and rejuvenators to see if there was any evidence of liminoid behavior in cruising needs and what they may be. Findings The results show that the important reasons to choose cruises for vacation are aligned with past literature showing that people choose cruises for vacation mostly for the good value of the food and beverage bundled with good climate, entertainment appropriate for quality time with family and for rest and relaxation. In addition, the results on motivations to go on a cruise show that lower-level needs on Maslow’s hierarchy of needs have more importance than the higher-level needs. Research limitations/implications The current study was conducted on an online platform. Future research with panels of cruise travelers across all the stages of liminoid behavior, before, during and after a cruise trip, may provide valuable findings in terms of changes in needs and motivations. Practical implications The inversionary tendency of cruise travelers implies for the cruise industry the need to create an alternative (or inversionary) routine restoring the basic needs, while still providing enough opportunities for self-actualization that may foster balanced travel experiences for human growth and development. Providing a more balanced product and service offering may be strategic for the cruise companies because the activities geared for higher-level needs may provide memorable experiences and hence induce consumer loyalty after the trip is completed. Social implications The focus on eating and drinking during cruises may be providing cruise travelers with instant gratification during the span of the cruise. However, the consequences for the individual travelers, the industry, destinations and the environment may not be as gratifying. For a more responsible tourism, cruise travel may need an image makeover highlighting different packages within a cruise to better align with the desired needs of different segments of cruisers. Originality/value The study contributes to the understanding of the second or “transition” stage in liminal theory in tourism and is one of the first to examine the liminoid state of mind using a basic-needs approach for studying cruise traveler needs. Further, it contributes by exploring liminoid behavior of a group of people in the context of the same type of travel, cruise, rather than investigating liminoid behavior across different types of travel, thus allowing segmentation possibilities for the cruise industry.


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