scholarly journals Influence of an Implant Fixture Including a Freely Removable Micro-Locking Implant Prosthesis on Peri-Implant Tissues and Implant Prostheses: A Prospective Clinical Study

2021 ◽  
Vol 10 (15) ◽  
pp. 3321
Author(s):  
Young-Gun Shin ◽  
Won-Tak Cho ◽  
Ho-Kyung Lim ◽  
Su-Hyun Hwang ◽  
Ji-Hyeon Bae ◽  
...  

This prospective study was undertaken to evaluate the clinical usefulness of a newly developed one-piece, screw-free, and micro-locking implant system, which was designed to overcome the shortcomings of the existing implant systems. Thirty-eight patients were recruited and randomly and equally assigned to an experimental group (micro-locking one-piece fixture, MLF; n = 19) or a control group (micro-locking abutment, MLA). Cumulative implant survival rates, marginal bone resorptions, probing depths, plaque indices, bleeding indices, and complications were obtained by using clinical and radiographic findings at 6 months and 12 months after prosthesis placement. Complications that occurred multiple times for single implants were counted. During the 12 month observation period, survival rates were 100% in both groups. No significant intergroup differences were observed for marginal bone resorption, probe depth, or bleeding index. However, mean plaque index was significantly lower in the MLF group at 12 months (p < 0.05). During the 12-month observation period, food impaction (26.3%) was the maincomplication in the MLF group and screw loosening (5.3%), prosthesis detachment (5.3%), and food impaction (5.3%) were observed in the MLA group. The results of this study suggest that the one-piece micro-locking implant system offers a predictable treatment method.

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Peng Li ◽  
Li He

With the accelerating pace of life, increasing stress and unhealthy diet make cardiovascular disease one of the important diseases that endanger human health, among which the incidence of acute angina is gradually increasing. At present, there are many clinical treatment studies on acute angina pectoris, but the relevant imaging analysis is very lacking. In order to study the clinical treatment of patients with acute angina pectoris and analyze the relevant medical images, to arrive at a more effective treatment method, this article launched an in-depth study. First, we selected 88 patients with acute angina in a hospital as the research object and randomly divided them into a control group (n = 44) and an experimental group (n = 44) Yan et al. (2020). The control group was treated with conventional acute angina pectoris drugs, while the experimental group was treated with clopidogrel on this basis. The two groups were treated at the same time, and the treatment time lasted for 3 months. Then, the risk factors of the two groups of patients were analyzed, and the differences were statistically significant ( P < 0.05 ). Then, the medical images of the two groups of patients were analyzed, and the diastolic blood pressure, systolic blood pressure, and coronary artery stenosis were compared before and after treatment. After treatment, the diastolic blood pressure and systolic blood pressure of the experimental group were 88.31 ± 3.15 mmHg and 125.63 ± 4.16 mmHg, respectively. The proportion of patients with zero-vessel disease and single-vessel disease in the experimental group increased to 15.91% and 56.82%. The treatment plan received by the experimental group patients had a better improvement effect. Finally, the clinical efficacy was compared. The total effective rates of the control and experimental groups were 72.7% and 88.6%, respectively. This shows that the treatment method adopted by the experimental group of patients has a better curative effect and is worthy of clinical promotion.


1987 ◽  
Author(s):  
H Ditter ◽  
Fr R Matthias ◽  
R Voss ◽  
P Rottger

Arachidonic acid metabolites seem to play a pivotal role in the pathophysiology of endotoxin (ET) shock. Therefore, attempts to intervene into the balance of eicosanoids may affect the course of ET shock. Several studies had shown a reduction of ET-induced mortality by non-steroidal antiinflammatory drugs in various animal species.We investigated whether an infusion of prostacyclin (PGI2) has an effect on survival rates and on the incidence of renal microclots in a rabbit shock model, which is based on an intravenous infusion of ET over 4 hours. Thirty animals being exposed to 75 μg/kg x h of lipopolysaccharide B, were allocated to three groups (E, El, EA; n=10 each), either receiving ET only (E), or PGI2 (500 ng/kg x min) simultaneously to ET (El), or aspirin (20 mg/kg) before ET (EA).A control group (C; saline infusion) consisted of 8 animals.At the end of the observation period (8 hours), the mortality of the treated animals (El and EA: 4/10 each) was significantly lower than in group E (8/10). However, only in the PGI2-treated group El a significant reduction of ET-induced glomerular fibrin deposition (GFD) was observed. Indices of GFD after semi-quantitative evaluation of renal slices were 10/27 (E), 1/24 (El), 3/21 (EA), and 0/24 (C). PGI2 exerted a platelet protective effect as shown by higher blood platelet counts (El 61.3 % vs. E 33.4 % of initial values), and a better preserved aggregation (El 60.5 % vs.E 31.7 %) and thromboxane formation capacity (El 52.0 ng/ml vs.E 23.4 ng/ml) of platelet rich plasma stimulated by 5 μg/ml collagen (all values at six hours after the start of ET infusion).ET caused a profound granulocytopenia which was not prevented by PGI2. Furthermore, PGI2 did not affect the ET-induced metabolic acidosis.These data confirm a beneficial effect of prostacyclin during a prolonged endotoxemia in rabbits, which may be a consequence of the known vasodilating, platelet inhibiting and cytoprotective properties of the substance.


Author(s):  
Ng Sau Ping ◽  
Mahendran Maniam

<p>Matriculation a pre-tertiary program offered by Ministry of Education for students who have completed their ‘Sijil Pelajaran Malaysia’s’ (SPM) examinations successfully. These excellent students will be required to sit for the Malaysian University English Test (MUET) before pursuing their studies in local colleges and universities. MUET comprises all the four language skills of listening, speaking, reading and writing. However, matriculation students are still unable to perform well in MUET examination especially the writing component. Researcher aimed to see whether Facebook group discussions can be used as a medium to improve writing skills of students. The main purpose of this study is to look at the effectiveness of Facebook group discussion in writing performance and college students’ perception of using Facebook discussion. This study tested the effect of Facebook discussions by comparing 2 groups of learners (a control group and an experimental group) on writing tasks. The scores of Pre and Post test for both groups will be compared after treatment method of Facebook group discussion on the experimental group. Learners’ attitudes towards the usage of Facebook group discussion and aspects of Facebook that help students to express their opinion. Discussions of the findings will include suggestions on whether Facebook discussions can be used to improve writing performance.</p>


2019 ◽  
Vol 85 (5) ◽  
pp. 539-548
Author(s):  
Zhongkun Zuo ◽  
Ke Ding ◽  
Tenglong Tang ◽  
Leiyi Zhang ◽  
Weihui Peng ◽  
...  

To explore the efficiency and safety of laparoscopic anus-conserving operation for ultralow rectal cancer, we retrospectively reviewed 236 patients with ultralow rectal cancer who underwent laparoscopic anus-conserving operation (experimental group, n = 124) or conventional open surgery (control group, n = 112). Operation-related indexes, pathological results of mesentery, incidence rates of postoperative complications, anus preservation rates, anal sphincter controllability after surgery, and survival rates of the first, second, and third years after operation were compared between the two groups. The amount of intraoperative bleeding, first postoperative exhaust time, abdominal drainage, pain score, and hospital stay in the experimental group were significantly less than those in the control group ( P < 0.05). There were no significant differences in the postoperative circumferential resection margin, distal resection margin, number of dissected lymph nodes, successful resection rate, and quality of mesorectum between the two groups ( P > 0.05). The total incidence rate of postoperative complications, anal sphincter controllability, and survival rates after surgery were similar between the two groups ( P > 0.05). The anus preservation rate of the experimental group (84.7%) was significantly higher than that of the control group (69.6%) ( P < 0.05). Laparoscopic anus-conserving operation is effective and safe in treatment of patients with ultralow rectal cancer, which has advantages such as small trauma, less intra-operative bleeding, short hospital stay, rapid recovery, a low incidence rate of postoperative complications, and a high anus-preserving rate, so it is worthy of clinical application.


Author(s):  
O. Karachynskyi

The article is dedicated to the research of identifying the changes of significant necessities, that are typical for thepersonality of combatants in the course of the rehabilitation period. In order to identify significant necessities, that are typical forthe personality of combatants the method of color selection has been used. It is referred to the necessities that are determinedby main colors: the necessity of satisfaction and affection, the necessity of self-empowerment, the necessity of achievement,obtainment, power; the necessity of social activity and emotional engagement. When interpreting the results, the orientationwas aimed at the first, second and seventh and eight positions, though we had the intention to receive the information concerning the main way of action and its purpose, the one that the researcher is planning to reach as well as his suppressednecessities.At the initial stage of research within the experimental group (EG) the main necessities and tendencies were focused onactivity, the emotional engagement, and simultaneously the necessity to lose the actual reality. At the final stage of researchprominent remains the necessity to stay active, and emotionally engaged there’s no longer a necessity to lose the actual real ity.Prior becomes the need to fortify ones’ position.The main necessities of the control group were: the need to sense intense affiliation, the tendency to achieve externalprotection and emotional comfort; the need to be emotionally engaged, active, the tendency to be passive. When comparing thefixed stages of the experiment we could obviously claim that the prior necessities of control groups under research havepractically not changed. However, at the final stages of research there turned out to be features of harmonizing the personality.


2015 ◽  
Vol 97 (3) ◽  
pp. 215-220 ◽  
Author(s):  
Y Li ◽  
X Meng

Introduction Although it has now been accepted that imatinib is a valid treatment for gastrointestinal stromal tumour (GIST) patients in the adjuvant setting, information on its clinical efficacy in improving the prognosis for patients with colorectal GISTs is limited. Methods The clinical and follow-up records of 42 colorectal GIST patients who underwent surgical resection at our institution between January 2004 and December 2013 were reviewed retrospectively. The effect of postoperative imatinib treatment on recurrence free survival and overall survival time was analysed with the Kaplan–Meier method and the multivariate Cox proportional hazards model. Results Sixteen patients were assigned to imatinib treatment (imatinib group) after surgical tumour resection while twenty-six patients did not receive any adjuvant treatment (control group). The one, three and five-year recurrence free survival rates were 100%, 90% and 77% respectively. This was significantly higher than in the control group (92%, 53% and 36%) (logrank test, p=0.012). The one, three and five-year overall survival rates were 100%, 91% and 68% in the imatinib group compared with 96%, 77% and 39% in the control group (logrank test, p=0.021). Analysis with the multivariate Cox regression model yielded similar results on the efficacy of adjuvant imatinib in prolonging both recurrence free survival (hazard ratio [HR]: 0.23, 95% confidence interval [CI]: 0.07–0.80) and overall survival (HR: 0.20, 95% CI: 0.05–0.91). Conclusions Adjuvant imatinib therapy seems to be effective in decreasing the risk of tumour occurrence and prolonging the overall survival time in colorectal GIST patients.


2019 ◽  
Vol 3 (4) ◽  
Author(s):  
Xiaoxu Shi ◽  
Lanying Qin ◽  
Jun Peng ◽  
Zishen Zhao ◽  
Haixiang Zhang

Objective: To investigate the clinical efficacy of plasma exchange therapy for autoimmune bullous skin disease. METHODS: Fifty patients with autoimmune bullous skin disease enrolled in our hospital from January 2018 to January 2019 were selected. The patients were grouped by treatment method: 25 control group patients were given conventional hormone therapy, while 25 experimental group patients were treated with plasma exchange therapy; efficacy of treatment was compared between two groups of patients. RESULTS: Initial dose, maximum dose, and cumulative dose of glucocorticoids were lower in experimental group patients than those in control group (P<0.05). Incidence of complication was lower in experimental group patients than those in control group (P<0.05); the difference was significant. There was no significant difference in short-term efficacy between the two groups (P>0.05). Conclusion: The application of plasma exchange therapy was effective for treatment of autoimmune bullous skin disease. It could reduce dosage amount of glucocorticoids and incidence of complications; its application can be promoted.


2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 180-180
Author(s):  
Lin Chen ◽  
Yingkun Ren ◽  
Yajie Zheng

180 Background: To evaluate the short- and long-term effects of two different surgery approaches for remnant gastric cancer after distal gastrectomy. Methods: Clinical data of 48 remnant gastric cancer patients were collected retrospectively from the period of January 1st 2010 to December 31st 2012 in this matched-pair study. Twenty four patients in the experimental group underwent radical surgery in antegrade approach (starting from the esophagus to the gastrointestinal anastomosis), another 24 matched patients in the control group underwent radical surgery in retrograde approach (starting from the gastrointestinal anastomosis to the esophagus). Constants in the study were patient age, the operating surgeon, Borrmann type, TNM stage and operation range. Pearsonχ2 testor t-test were used to compare the clinicopathological characteristics between the two groups. Survival rates of 1- and 3-years were analyzed with Kaplan-Meier survival curve and compared with Log-rank test. Results: The 48 patients were treated successfully without any mortality during their hospital stay. The mean operative time and bleeding volume in the experimental and control groups were (126.6±5.7) min and (154.1±23.9)ml , and (168.3±11.7) min and (180.8±15.0)ml respectively. The difference in the mean operative times (t = -3.089, P = 0.005) and the mean bleeding volumes (t = -3.269, P = 0.004) were statistically significant. The average hospital stay after surgery and the average number of lymph nodes resected were (9.5±0.9) days and 18.7±1.6 in the experimental group,(9.2±0.8) day and 17.4±1.4 in the control group. There was no statistical differences between the two groups in terms of the average hospital stay (t = 0.692, P = 0.496) and the average number of resected lymph nodes (t = 2.101, P = 0.247). The overall 1- year and 3-years survival rates were 75%, 49% in the experimental group and 67%, 35% in the control group. There was also no statistical difference in the 1-year (P = 0.745) and 3-years (P = 0.878) survival rates. Conclusions: Compared with retrograde approach, performing radical surgery in antegrade way for remnant gastric cancer patients can shorten the operation time, reduce blood loss and simplify the operation procedure.


1992 ◽  
Vol 7 (2) ◽  
pp. 59-63 ◽  
Author(s):  
J. P. Travers ◽  
K. L. Dalziel ◽  
G. S. Makin

Objective: To evaluate the effective duration of compression of acrylic adhesive bandaging compared to non-adhesive bandaging and to compare rate of venous ulcer healing using one layer adhesive bandaging as compared to standard three layer bandaging. Design: The first trial involved patients who had undergone bilateral operations for varicose veins. Adhesive acrylate bandage was applied to the experimental limb and non-adhesive crepe to the control limb. The second trial involved patients with venous ulcers randomly allocated to two groups. The experimental group used the one layer acrylic adhesive bandage whilst the control was treated by the three layer bandage technique (zinc oxide paste bandage followed by a non-adhesive compression bandage and tubular overlay). Setting: Hospital patients in the first trial and clinic patients in the second. Patients, participants: First trial, 11 patients with bilateral varicose veins of which 10 completed. Second trial, 15 patients in the experimental group and 12 patients in the control group all of which completed. Results: Non-adhesive bandaging lost effective compression after 24 hours. Acrylic adhesive bandage maintained effective compression after 1 week. The rate of venous ulcer healing was similar between the one layer adhesive bandage group and three layer group. One layer adhesive bandaging took only one quarter of the time to apply (p<0.01%). Conclusions: Adhesive bandaging produced more effective sustained compression than non-adhesive crepe. Adhesive bandaging was as effective as the currently used three layer bandaging technique in healing venous ulcers and was quicker to apply.


2020 ◽  
pp. 23-24
Author(s):  
Vera N. Makarova ◽  

The article reflects observations on calves with different ways of keeping. Two groups of newborn calves were selected at the dairy complex (n=33). The calves of the control group were raised indoors in the traditional way in individual cages, and the experimental group was outdoors in the houses. The experiment was conducted from March to June. For the first 10 days, all calves were measured body temperature, pulse, respiration, blood samples for 1, 5, 10, 20 and 30 days of life were studied, incidence was taken into account. The heart rate in both groups gradually decreased by day 10. In the experimental group, this decrease was less pronounced and on average over the observation period, the pulse rate was 128 or 8 beats higher than in the control. The respiratory rate in calves of both groups had a general tendency to decrease. In experimental calves, this indicator was more constant than in controls. In calves of the experimental group, the average daily gain was 69.0 g higher, and the incidence was 14.9% lower compared to the calves of the control group. Authors established activation of metabolism, increase in natural resistance, weight gain and decrease in the incidence of disease in calves bred in the open air in individual houses.


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