scholarly journals Antimicrobial Activity of 3D-Printed Acrylonitrile Butadiene Styrene (ABS) Polymer-Coated with Silver Nanoparticles

Materials ◽  
2021 ◽  
Vol 14 (24) ◽  
pp. 7681
Author(s):  
Isabel Tse ◽  
Atishay Jay ◽  
Ina Na ◽  
Sean Murphy ◽  
Nereida Niño-Martínez ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Medical Devices ◽  
Antimicrobial Properties ◽  
Acrylonitrile Butadiene Styrene ◽  
Healthcare Associated Infections ◽  
Wide Range ◽  
3D Printed ◽  
Microbial Strains ◽  
Healthcare Associated ◽  
Butadiene Styrene

Medical devices with antimicrobial properties are a potential long-term solution to the high rate of multi-drug-resistant healthcare-associated infections. Silver nanoparticles (AgNPs) are an established agent for effectively eliminating a wide range of microbial strains. AgNPs have been commonly incorporated into traditional plastic materials; however, recently, there has been increased interest in using AgNPs combined with 3D-printing technology for medical devices due to the accessibility and customizability of 3D-printed products. This study reports a novel method of utilizing acetone to partially dissolve 3D-printed polymer acrylonitrile butadiene styrene (ABS) plastic to attach a layer of AgNPs. The antimicrobial properties of this AgNP-coated surface were tested against several microbial strains prevalent in healthcare-associated infections. AgNP-coated ABS (AgNP-ABS) plastic demonstrated significant elimination of viable bacteria within 4 h for all tested bacterial species (Acinetobacter baumannii, non-pathogenic and pathogenic Escherichia coli, Pseudomonas aeruginosa, and methicillin-resistant Staphylococcus aureus) and within 19 h for the tested fungus Candida albicans. The longevity of adhesion of AgNPs to the ABS plastic was assessed by checking antibacterial activity against A. baumannii after repeat use cycles. AgNP-ABS plastic showed decreased antibacterial efficacy with repeated use but maintained the ability to eliminate microbes within 3 h for up to eight use cycles. The AgNP-coated ABS plastic showed efficacy as an antimicrobial surface, and future studies will consider its applicability in the production of medical devices.

scholarly journals The Effect of Disinfectants Absorption and Medical Decontamination on the Mechanical Performance of 3D-Printed ABS Parts

Polymers ◽  
2021 ◽  
Vol 13 (23) ◽  
pp. 4249
Author(s):  
Diana Popescu ◽  
Florin Baciu ◽  
Catalin Gheorghe Amza ◽  
Cosmin Mihai Cotrut ◽  
Rodica Marinescu
Keyword(s):  
3D Printing ◽  
Medical Devices ◽  
Mechanical Performance ◽  
Acrylonitrile Butadiene Styrene ◽  
Extrusion Process ◽  
Air Gaps ◽  
Safety Issues ◽  
Gas Plasma ◽  
3D Printed ◽  
Butadiene Styrene

Producing parts by 3D printing based on the material extrusion process determines the formation of air gaps within layers even at full infill density, while external pores can appear between adjacent layers making prints permeable. For the 3D-printed medical devices, this open porosity leads to the infiltration of disinfectant solutions and body fluids, which might pose safety issues. In this context, this research purpose is threefold. It investigates which 3D printing parameter settings are able to block or reduce permeation, and it experimentally analyzes if the disinfectants and the medical decontamination procedure degrade the mechanical properties of 3D-printed parts. Then, it studies acetone surface treatment as a solution to avoid disinfectants infiltration. The absorption tests results indicate the necessity of applying post-processing operations for the reusable 3D-printed medical devices as no manufacturing settings can ensure enough protection against fluid intake. However, some parameter settings were proven to enhance the sealing, in this sense the layer thickness being the most important factor. The experimental outcomes also show a decrease in the mechanical performance of 3D-printed ABS (acrylonitrile butadiene styrene) instruments treated by acetone cold vapors and then medical decontaminated (disinfected, cleaned, and sterilized by hydrogen peroxide gas plasma sterilization) in comparison to the control prints. These results should be acknowledged when designing and 3D printing medical instruments.

scholarly journals Innovative Development of Batch Dyed 3D Printed Acrylonitrile/Butadiene/Styrene Objects

Molecules ◽  
2021 ◽  
Vol 26 (21) ◽  
pp. 6637
Author(s):  
Suzana Kutnjak-Mravlinčić ◽  
Ana Sutlović ◽  
Martinia Ira Glogar ◽  
Sanja Ercegović Ražić ◽  
Damir Godec
Keyword(s):  
Abrasion Resistance ◽  
Acrylonitrile Butadiene Styrene ◽  
Creative Industries ◽  
Added Value ◽  
Disperse Dyes ◽  
Wide Range ◽  
Scientific Papers ◽  
3D Printed ◽  
Footwear Design ◽  
Butadiene Styrene

According to the great impact of additive technology on the development of modern industry, a lot of research is being done to obtain 3D printed parts with better properties. This research is extremely important because there are no scientific papers in the field of post dyeing of acrylonitrile/butadiene/styrene (ABS) 3D printed parts. The experiment was carried out using disperse dyes on ABS specimens. The obtained coloration of the specimens was in the primary colors (yellow, red, and blue) in the specified dyestuff concentration range and was evaluated using an objective CIELab system. Based on the obtained color parameters, remission values and Kubelka-Munk coefficient, dye mixtures and an ombre effect were performed to obtain patterns in the desired hues. Abrasion resistance of disperse dyed specimens was tested using different abrasive materials over a wide range of fineness to simulate different indoor and outdoor soils and was compared to abrasion resistance of specimens produced from the industrially dyed wire with the master batch. The results show that 3D printed ABS products can be produced in one or more desired shades with satisfactory abrasion resistance. This undoubtedly represents the added value of 3D printed ABS parts and extends their application to the field of creative industries and design, specifically footwear design.

scholarly journals Essential work of fracture assessment of acrylonitrile butadiene styrene (ABS) processed via fused filament fabrication additive manufacturing

2021 ◽  
Author(s):  
Pawan Verma ◽  
Jabir Ubaid ◽  
Andreas Schiffer ◽  
Atul Jain ◽  
Emilio Martínez-Pañeda ◽  
...  
Keyword(s):  
Acrylonitrile Butadiene Styrene ◽  
Essential Work ◽  
Fused Filament Fabrication ◽  
Essential Work Of Fracture ◽  
Fracture Properties ◽  
Raster Angle ◽  
3D Printed ◽  
Printing Direction ◽  
Work Of Fracture ◽  
Butadiene Styrene

AbstractExperiments and finite element (FE) calculations were performed to study the raster angle–dependent fracture behaviour of acrylonitrile butadiene styrene (ABS) thermoplastic processed via fused filament fabrication (FFF) additive manufacturing (AM). The fracture properties of 3D-printed ABS were characterized based on the concept of essential work of fracture (EWF), utilizing double-edge-notched tension (DENT) specimens considering rectilinear infill patterns with different raster angles (0°, 90° and + 45/− 45°). The measurements showed that the resistance to fracture initiation of 3D-printed ABS specimens is substantially higher for the printing direction perpendicular to the crack plane (0° raster angle) as compared to that of the samples wherein the printing direction is parallel to the crack (90° raster angle), reporting EWF values of 7.24 kJ m−2 and 3.61 kJ m−2, respectively. A relatively high EWF value was also reported for the specimens with + 45/− 45° raster angle (7.40 kJ m−2). Strain field analysis performed via digital image correlation showed that connected plastic zones existed in the ligaments of the DENT specimens prior to the onset of fracture, and this was corroborated by SEM fractography which showed that fracture proceeded by a ductile mechanism involving void growth and coalescence followed by drawing and ductile tearing of fibrils. It was further shown that the raster angle–dependent strength and fracture properties of 3D-printed ABS can be predicted with an acceptable accuracy by a relatively simple FE model considering the anisotropic elasticity and failure properties of FFF specimens. The findings of this study offer guidelines for fracture-resistant design of AM-enabled thermoplastics. Graphical abstract

scholarly journals Does vaporized hydrogen peroxide sterilization affect the geometrical properties of anatomic models and guides 3D printed from computed tomography images?

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Mauricio Toro ◽  
Aura Cardona ◽  
Daniel Restrepo ◽  
Laura Buitrago
Keyword(s):  
Computed Tomography ◽  
Hydrogen Peroxide ◽  
Dimensional Stability ◽  
Acrylonitrile Butadiene Styrene ◽  
Dimensional Error ◽  
Material Extrusion ◽  
Anatomic Models ◽  
3D Printed ◽  
Mean Differences ◽  
Butadiene Styrene

Abstract Background Material extrusion is used to 3D print anatomic models and guides. Sterilization is required if a 3D printed part touches the patient during an intervention. Vaporized Hydrogen Peroxide (VHP) is one method of sterilization. There are four factors to consider when sterilizing an anatomic model or guide: sterility, biocompatibility, mechanical properties, and geometric fidelity. This project focuses on geometric fidelity for material extrusion of one polymer acrylonitrile butadiene styrene (ABS) using VHP. Methods De-identified computed tomography (CT) image data from 16 patients was segmented using Mimics Innovation Suite (Materialise NV, Leuven, Belgium). Eight patients had maxillary and mandibular defects depicted with the anatomic models, and eight had mandibular defects for the anatomic guides. Anatomic models and guides designed from the surfaces of CT scan reconstruction and segementation were 3D printed in medical-grade acrylonitrile butadiene styrene (ABS) material extrusion. The 16 parts underwent low-temperature sterilization with VHP. The dimensional error was estimated after sterilization by comparing scanned images of the 3D printed parts. Results The average of the estimated mean differences between the printed pieces before and after sterilization were − 0,011 ± 0,252 mm (95%CI − 0,011; − 0,010) for the models and 0,003 ± 0,057 mm (95%CI 0,002; 0,003) for the guides. Regarding the dimensional error of the sterilized parts compared to the original design, the estimated mean differences were − 0,082 ± 0,626 mm (95%CI − 0,083; − 0,081) for the models and 0,126 ± 0,205 mm (95%CI 0,126, 0,127) for the guides. Conclusion This project tested and verified dimensional stability, one of the four prerequisites for introducing vaporized hydrogen peroxide into 3D printing of anatomic models and guides; the 3D printed parts maintained dimensional stability after sterilization.

scholarly journals Impact of Healthcare-Associated Infections Connected to Medical Devices—An Update

2021 ◽  
Vol 9 (11) ◽  
pp. 2332
Author(s):  
Nitin Chandra Teja Dadi ◽  
Barbora Radochová ◽  
Jarmila Vargová ◽  
Helena Bujdáková
Keyword(s):  
Medical Devices ◽  
Surgical Site Infections ◽  
Central Line ◽  
Ventilator Associated Pneumonia ◽  
Healthcare Associated Infections ◽  
Care Bundles ◽  
Planktonic Form ◽  
Novel Approaches ◽  
Healthcare Associated ◽  
The Impact

Healthcare-associated infections (HAIs) are caused by nosocomial pathogens. HAIs have an immense impact not only on developing countries but also on highly developed parts of world. They are predominantly device-associated infections that are caused by the planktonic form of microorganisms as well as those organized in biofilms. This review elucidates the impact of HAIs, focusing on device-associated infections such as central line-associated bloodstream infection including catheter infection, catheter-associated urinary tract infection, ventilator-associated pneumonia, and surgical site infections. The most relevant microorganisms are mentioned in terms of their frequency of infection on medical devices. Standard care bundles, conventional therapy, and novel approaches against device-associated infections are briefly mentioned as well. This review concisely summarizes relevant and up-to-date information on HAIs and HAI-associated microorganisms and also provides a description of several useful approaches for tackling HAIs.

scholarly journals Biogenic Synthesis of Silver Nanoparticles with Antimicrobial Properties

2020 ◽  
Vol 5 (2) ◽  
Author(s):  
Evangelia A Pavlatou
Keyword(s):  
Silver Nanoparticles ◽  
Antimicrobial Properties ◽  
Public Health Problem ◽  
Integrated Approach ◽  
Synthetic Methods ◽  
Synthesis Process ◽  
Major Public Health Problem ◽  
Biogenic Synthesis ◽  
Wide Range ◽  
Bacteria And Fungi

The transmission of a wide range of diseases, related to the infection by pathogenic microorganisms is a major public health problem that daily endangers the safety of human population. Silver has been thoroughly studied and used against bacteria due to its antimicrobial properties. Nanostructured silver gathers all the advantages of the silver itself, as well as the advanced performance of the nanomaterials. Thus, currently, silver nanoparticles constitute the most widely used kind of nanoparticles in biomedicine, due to their attractive antimicrobial properties. A variety of physical and chemical methods are employed for the AgNPs synthesis. However, many of them include the use of toxic reagents or require large amounts of energy, during the synthesis process. For this reason, many eco-friendly methods are proposed in order to synthesize AgNPs. Hence, biogenic synthesis of AgNPs, utilizing biological resources opens a novel route for the development of alternative production processes.These methods seem to have significant advantages, as the extracts contribute positively to the formation and enhancement of the antimicrobial activity of AgNPs, also acting as protective agents of the produced particles. In this review an integrated approach of AgNPs bio-synthetic methods using microorganisms, such as bacteria and fungi, plants and plant extracts, as well as several templates, like DNA and viruses is discussed, shedding light on the comparative advantages of them.

scholarly journals Enhanced antibacterial efficacy of nitric oxide releasing thermoplastic polyurethanes with antifouling hydrophilic topcoats

2017 ◽  
Vol 5 (7) ◽  
pp. 1246-1255 ◽  
Author(s):  
Priyadarshini Singha ◽  
Jitendra Pant ◽  
Marcus J. Goudie ◽  
Christina D. Workman ◽  
Hitesh Handa
Keyword(s):  
Nitric Oxide ◽  
Medical Devices ◽  
Antimicrobial Efficacy ◽  
Healthcare Associated Infections ◽  
Antibacterial Efficacy ◽  
Thermoplastic Polyurethanes ◽  
Nitric Oxide Releasing ◽  
Healthcare Associated

Hydrophilic antifouling topcoat combined with nitric oxide releasing polymer to enhance antimicrobial efficacy and combat healthcare-associated infections caused by medical devices.

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