scholarly journals Microbial Secondary Metabolism and Biotechnology

2022 ◽  
Vol 10 (1) ◽  
pp. 123
Author(s):  
Mireille Fouillaud ◽  
Laurent Dufossé

In recent decades scientific research has demonstrated that the microbial world is infinitely richer and more surprising than we could have imagined. Every day, new molecules produced by microorganisms are discovered, and their incredible diversity has not yet delivered all of its messages. The current challenge of research is to select from the wide variety of characterized microorganisms and compounds, those which could provide rapid answers to crucial questions about human or animal health or more generally relating to society’s demands for medicine, pharmacology, nutrition or everyday well-being.

Author(s):  
Nirit Putievsky Pilosof ◽  
Yasha Jacob Grobman

Objective The study examines the integration of the Evidence-based Design (EBD) approach in healthcare architecture education in the context of an academic design studio. Background Previous research addressed the gap between scientific research and architectural practice and the lack of research on the use of the EBD approach in architectural education. Methods The research examines an undergraduate architectural studio to design a Maggie’s Centre for cancer care in Israel and evaluates the impact of the EBD approach on the design process and design outcomes. The research investigates the impact of the integration of three predesign tasks: (1) literature review of healing architecture research, (2) analysis and comparison of existing Maggie’s Centres, and (3) analysis of the context of the design project. Results The literature review of scientific research supported the conceptual design and development of the projects. The analysis of existing Maggie’s centers, which demonstrated the interpretation of the evidence by different architects, developed the students’ ability to evaluate EBD in practice critically, and the study of the projects’ local context led the students to define the relevance of the evidence to support their vision for the project. Conclusions The research demonstrates the advantages of practicing EBD at an early stage in healthcare architectural education to enhance awareness of the impact of architectural design on the users’ health and well-being and the potential to support creativity and innovative design. More studies in design studios are needed to assess the full impact of integrating EBD in architectural education.


2020 ◽  
Vol 29 (1) ◽  
pp. 37-43
Author(s):  
H Potockova ◽  
P Kusnierik ◽  
J Dohnal

Medical devices form a large heterogeneous group of products ranging from simple tools to medical testing and implants, the safety and efficacy of which are strictly regulated in all developed countries. Thanks to the health and cost benefits, medical devices have also found their way into veterinary medicine but, surprisingly, the regulation of these products is far less complex or, in some cases, missing altogether. Given the complexity and potential hazards of certain veterinary devices, the current state of affairs may lead to health and safety risks, both for animals and personnel involved. This review is the first to systematically map the current situation in the EU, revealing health and safety risks in practice for both animals and personnel involved and discussing them in a broader context. Only six out of the EU's 28 member states (Belgium, Croatia, Czech Republic, Germany, Hungary, and Slovakia) were found to have at least a degree of regulation of veterinary devices. As a result, a single product may be regulated as a veterinary medicinal product, a veterinary medical device or not be regulated at all, depending on the particular EU member state in question. As things stand, veterinary medicine makes use of all kinds of medical devices, including human products, regardless of their regulatory status and (pre-market) control. However, the use of such devices may influence the health and well-being of animals. Several measures are therefore suggested to attain the required levels of safety and efficacy surveillance for veterinary medical devices without creating excessive administration.


2011 ◽  
Vol 26 (S1) ◽  
pp. s96-s96
Author(s):  
P. Hollier

Animal production is an important component to economic stability and food security in developing country. Economic development programs have targeted agriculture in developing country as a means of decreasing poverty and empowering vulnerable populations throughout much of the developing world. Disasters due to natural and man-made hazards that impact animal agriculture have a disproportionate impact on the rural poor and vulnerable populations affecting the economic well being and health of the greater population. Protection of livelihoods dependent on animal agriculture is important to consider in community resilience and humanitarian assistance activities that range from capacity building through response and recovery. In order to meet the challenges of the next generation of global health threats, policy, research, and practice must adopt a new cross-cutting approach that targets the human-animal-ecologic interface taking into account political, socioeconomic, and cultural factors.


2003 ◽  
Vol 31 (1_suppl) ◽  
pp. 132-137 ◽  
Author(s):  
Kathryn A.L. Bayne

The increasing emphasis on the provision of environmental enrichment to laboratory animals, vis-à-vis the USDA Animal Welfare Regulations, the Guide for the Care and Use of Laboratory Animals (NRC 1996), and a potential forthcoming policy from the USDA on the subject, can be difficult to accommodate in a toxicology research environment. A summary will be provided of current requirements and recommendations. Then, strategies for meeting regulatory requirements will be described for non-rodent animals used in toxicology research. These strategies will address methods of both social enrichment, such as pair or group housing, as well as non-social enrichment, such as cage furniture, food enrichments, and toys. In addition, the value of positive interactions with staff (e.g., through training paradigms or socialization programs) will also be discussed. Apparent in the discussion of these strategies will be an overarching recognition of the necessity to avoid introducing confounding variables into the research project and to avoid compromising animal health. The roles of the Institutional Animal Care and Use Committee (IACUC) and the attending veterinarian in helping scientists balance animal well-being, the scientific enterprise and the regulatory environment will be described.


Author(s):  
Kim A. Kayunze ◽  
Angwara D. Kiwara ◽  
Eligius Lyamuya ◽  
Dominic M. Kambarage ◽  
Jonathan Rushton ◽  
...  

One-health approaches have started being applied to health systems in some countries in controlling infectious diseases in order to reduce the burden of disease in humans, livestock and wild animals collaboratively. However, one wonders whether the problem of lingering and emerging zoonoses is more affected by health policies, low application of one-health approaches, or other factors. As part of efforts to answer this question, the Southern African Centre for Infectious Disease Surveillance (SACIDS) smart partnership of human health, animal health and socio-economic experts published, in April 2011, a conceptual framework to support One Health research for policy on emerging zoonoses. The main objective of this paper was to identify which factors really affect the burden of disease and how the burden could affect socio-economic well-being. Amongst other issues, the review of literature shows that the occurrence of infectious diseases in humans and animals is driven by many factors, the most important ones being the causative agents (viruses, bacteria, parasites, etc.) and the mediator conditions (social, cultural, economic or climatic) which facilitate the infection to occur and hold. Literature also shows that in many countries there is little collaboration between medical and veterinary services despite the shared underlying science and the increasing infectious disease threat. In view of these findings, a research to inform health policy must walk on two legs: a natural sciences leg and a social sciences one.


Foods ◽  
2018 ◽  
Vol 7 (12) ◽  
pp. 195 ◽  
Author(s):  
Victoria Bell ◽  
Jorge Ferrão ◽  
Lígia Pimentel ◽  
Manuela Pintado ◽  
Tito Fernandes

Changes in present-day society such as diets with more sugar, salt, and saturated fat, bad habits and unhealthy lifestyles contribute to the likelihood of the involvement of the microbiota in inflammatory diseases, which contribute to global epidemics of obesity, depression, and mental health concerns. The microbiota is presently one of the hottest areas of scientific and medical research, and exerts a marked influence on the host during homeostasis and disease. Fermented foods and beverages are generally defined as products made by microbial organisms and enzymatic conversions of major and minor food components. Further to the commonly-recognized effects of nutrition on the digestive health (e.g., dysbiosis) and well-being, there is now strong evidence for the impact of fermented foods and beverages (e.g., yoghurt, pickles, bread, kefir, beers, wines, mead), produced or preserved by the action of microorganisms, on general health, namely their significance on the gut microbiota balance and brain functionality. Fermented products require microorganisms, i.e., Saccharomyces yeasts and lactic acid bacteria, yielding alcohol and lactic acid. Ingestion of vibrant probiotics, especially those contained in fermented foods, is found to cause significant positive improvements in balancing intestinal permeability and barrier function. Our guts control and deal with every aspect of our health. How we digest our food and even the food sensitivities we have is linked with our mood, behavior, energy, weight, food cravings, hormone balance, immunity, and overall wellness. We highlight some impacts in this domain and debate calls for the convergence of interdisciplinary research fields from the United Nations’ initiative. Worldwide human and animal medicine are practiced separately; veterinary science and animal health are generally neither considered nor inserted within national or international Health discussions. The absence of a clear definition and subsequent vision for the future of One Health may act as a barrier to transdisciplinary collaboration. The point of this mini review is to highlight the role of fermented foods and beverages on gut microbiota and debate if the need for confluence of transdisciplinary fields of One Health is feasible and achievable, since they are managed by separate sectors with limited communication.


2018 ◽  
Vol 2 (2) ◽  
pp. 37-54
Author(s):  
Zoha Adel Mahmoud

institution is one of the highest institutions that have the task of providing the development needs of the community of specialists in various fields, in addition to being the centers of scientific research and applied to ensure economic and social progress It enriches decision makers with expertise and skills and thus controls political performance. In any society, the university can not play its full role in social change without interaction between the individual on the one hand and the social environment on the other, Social and interdependent Ah syndrome change, they strengthen the skills, and enrich the spirit of innovation of the individual, and raise the level of social progress. It helps to improve the conditions of the poor segments of the population and facilitates the employment opportunities of the individuals imposed by the society as they meet the needs of the individual and society of different professions, thus providing an opportunity for production and thus have a positive impact on the standard of living to achieve the well-being of the individual and the citizen. The interest reflected on the progress, such as Germany, which was interested in it became one of the main reasons that led to the rise of Germany from the ruins of the Second World War as well as the State of Malaysia, which moved from developing countries to the second world countries by changing the plan Colleges and institutes of universities. In 2020, Malaysia will be among the developed countries. In these countries, higher education, vocational training and training are viewed as a basis for life supplementation and are seen as a major means of improving and upgrading society. If we are to explore the dimensions of education in the 21st century, one of the pillars of education is learning for action, Usually involves the acquisition of skills and the linking of knowledge to practice as an essential part of the training and rehabilitation of the individual for practical life. Hence, such new trends in linking educational preparation to work have been imposed by the labor market and the working life in its new forms. Production and service facilities, The advanced, assumed graduates who can be employed and absorbed can contribute to the development of competitiveness, to provide innovations and creations to achieve the competitive advantage of the enterprise, and to improve production and productivity based primarily on the acquisition and application of knowledge. Gamerdinger reveals that the new technology does not accelerate the possibilities for sound economic policies and increasing global trade, and this requires strategies to develop work related to the development of human performance, and in order to face the state of chronic unemployment globally, education policies are headed towards the so-called reverse conversion as many graduates of specializations Literaries choose vocational and technical education in technical and community colleges. Unemployment in the Arab world carries certain characteristics that must be taken into account when developing the solutions available to them. The most important of these characteristics are: Unemployment is a youth phenomenon. Weak professional experience available to the unemployed. Lack of targeted planning for the labor market. The large gap between the outputs of higher education for youth and the requirements of the labor market. The most important recommendations aimed at enhancing the role of universities in Iraq are: 1 - the operation of labor graduates of technical and technical institutes in the industrial field in order to promote them and eliminate unemployment and increase the hard currency as an important category of Iraqi society, which contributes actively to the renaissance of the country. Linking the Ministry of Industry and Commerce with the Ministry of Higher Education and Scientific Research to be managed by the Minister of Education alone. The Ministry is keen on the funds of the Iraqi people and contributes to the development of the industrial and commercial sectors with the help of professors and university students. 3 - the need to match the needs of the market and education outputs to reduce unemployment, in addition to the vocational education has become an urgent need at this stage to keep pace with the needs of life in society away from the negative view of this education. 4 - Increasing the number of technical workshops and providing them with the means of material in order to provide the university student maximum desired learning. Enhancing the role of higher education in building a broader partnership and cooperation with various other community institutions (public, private and private sector). 6 - Re-admission plan in universities by making the number of admissions in scientific colleges more than the number of admissions in the humanitarian colleges. 7 - Attracting foreign investment companies to invest natural resources in Iraq such as phosphate, natural gas, oil, oil shale, uranium, silica and geothermal energy for the recovery of the economy and the trend towards domestic consumption.


Author(s):  
Konstantinos Apostolou ◽  
Danai Kazantzidou-Firtinidou ◽  
Ilias Gkotsis ◽  
George Eftychidis

The chapter is an overview of important timely concepts with a focus on the safety and security of critical infrastructures (CIs). The content is a result of triangulation of sources from the fields of academia, best practices, legislation, and scientific research. The protection of CIs has been a popular topic of discussion through recent years but also a topic for initiative towards the undisrupted function, prosperity and well-being of nations in a world of interconnections and dependencies. In respect to that, the following content offers input which will assist in the understanding of the concepts surrounding the safety and security of CIs while combining theoretical approaches with practical guidelines for the composition of a business continuity plan. The chapter also discusses the factors contributing to the criticality of technical infrastructures as part of a nation or a cross-border network, the threats to which a CI can be exposed to whether these are natural or man-made.


2020 ◽  
pp. 1-14
Author(s):  
Johanna F. Lindahl ◽  
Florence Mutua ◽  
Delia Grace

Abstract Livestock interventions can improve nutrition, health, and economic well-being of communities. The objectives of this review were to identify and characterize livestock interventions in developing countries and to assess their effectiveness in achieving development outcomes. A scoping review, guided by a search strategy, was conducted. Papers needed to be written in English, published in peer-reviewed journals, and describe interventions in animal health and production. Out of 2739 publications systematically screened at the title, abstract, and full publication levels, 70 met our inclusion criteria and were considered in the study. Eight relatively high-quality papers were identified and added, resulting in 78 reviewed publications. Only 15 studies used randomized controlled trial designs making it possible to confidently link interventions with the resulting outcomes. Eight studies had human nutrition or health as outcomes, 11 focused on disease control, and four were on livestock production. Eight interventions were considered successful, but only four were scalable. We found good evidence that livestock-transfer programs, leveraging livestock products for nutrition, and helping farmers manage priority diseases, can improve human well-being. Our report highlights challenges in garnering evidence for livestock interventions in developing countries and provides suggestions on how to improve the quantity and quality of future evaluations.


Author(s):  
Svetlana I. Grudina

The labor market is an important indicator of economic development. The primary task of modern scientific research is to find a solution to the issues of development of social and economic well-being in a transformational economy, as the phase of changes and rethinking of experience affects almost all spheres of human activity. The attitude that one has towards their work is also being reconsidered. Human labour is being more and more replaced by machine labour, robotics is being introduced, different processes are automated, digitalized. All this reflected in the qualitative and semantic component of labour, which acquires the features of «liberated labour» from the «alienated labour», according to the theory of Karl Marx, where the boundaries between the worker and resting time are being erased. Nowadays the progress in the field of digital and computer technologies of the industrial sector is carried out at a high speed and leads to the inability of functioning by the old principles of «saving on creativity». Scientific novelty of the research work is presented in the theoretical formation of the category «liberated» labour. Thу author addresses the essential characteristics of the category of «liberated labour», analyzes the classification of labour as a category of economics, reveals the prospects for the development of the category of «alienated» and «liberated» labour, takes the gender specifics and modern realities of socio-economic transformations into the account; the author developed a set of theoretical provisions, methodological approaches and practical recommendations for the formation of an environment of «liberated labour». The theoretical and methodological issues of the intensifying usage of liberated labour are applying the effect of the entirety and are presented by supplementing in the field of terminological apparatus by the author's concept of «liberated labour». The contours of innovative reproduction are substantiated, they are proposed to be formed on the basis of the creation of institutions for the regulation and standardization of work of a new generation, the opening of researching laboratories that study labour activity.


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