scholarly journals Responses to Ecopollutants and Pathogenization Risks of Saprotrophic Rhodococcus Species

Pathogens ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 974
Author(s):  
Irina B. Ivshina ◽  
Maria S. Kuyukina ◽  
Anastasiia V. Krivoruchko ◽  
Elena A. Tyumina
Keyword(s):  
Survival Strategies ◽  
Complex Life Cycle ◽  
Anthropogenic Pressure ◽  
Resting Cells ◽  
Organic Substrates ◽  
Negative Effects ◽  
Anthropogenic Pollutants ◽  
Rhodococcus Species ◽  
Wide Range ◽  
Rigid Cell Wall

Under conditions of increasing environmental pollution, true saprophytes are capable of changing their survival strategies and demonstrating certain pathogenicity factors. Actinobacteria of the genus Rhodococcus, typical soil and aquatic biotope inhabitants, are characterized by high ecological plasticity and a wide range of oxidized organic substrates, including hydrocarbons and their derivatives. Their cell adaptations, such as the ability of adhering and colonizing surfaces, a complex life cycle, formation of resting cells and capsule-like structures, diauxotrophy, and a rigid cell wall, developed against the negative effects of anthropogenic pollutants are discussed and the risks of possible pathogenization of free-living saprotrophic Rhodococcus species are proposed. Due to universal adaptation features, Rhodococcus species are among the candidates, if further anthropogenic pressure increases, to move into the group of potentially pathogenic organisms with “unprofessional” parasitism, and to join an expanding list of infectious agents as facultative or occasional parasites.

Brief history and ways of further development of the department of hydraulic engineering and hydraulics FSBI «VNIIGiM named after A.N. Kostyakov»

2020 ◽  
pp. 18-23
Author(s):  
Alexey Shcherbakov ◽  
Valentin Zhezmer
Keyword(s):  
Land Reclamation ◽  
Water Source ◽  
Water Sources ◽  
Hydraulic Engineering ◽  
Negative Effects ◽  
Extensive Experience ◽  
Safety Level ◽  
Theoretical Substantiation ◽  
Wide Range ◽  
Construction Operation

Department of hydraulic engineering and hydraulics FGBNU «VNIIGiM them. A.N. Kostyakova «has a long history. For many years, the department’s staff has been such scientists and water engineers with extensive experience as M.A. Volynov, V.S. Verbitsky, S.S. Medvedev, N.V. Lebedev, B.C. Panfilov, T.G. Voynich-Syanozhentsky, V.A. Golubkova, G.V. Lyapin and others. The department solved a wide range of tasks, the main areas of research were the following: – theoretical and applied hydrodynamics and hydraulics, with reference to the open channel flows that affect the state and level of safety of the hydraulic structures; – integrated use and protection of water bodies – water sources and water sources of water resources used in land reclamation; – development of measures and technical solutions for the protection of objects from the negative effects of water; – theoretical substantiation of works to improve the safety level of the GTS (declaration); – development and implementation of digitalization methods for solving design, construction, operation and control of landreclamation facilities. Currently, promising areas of research is the development of a decision-making algorithm in the designation of measures to rationalize the provision of resources to water amelioration. The algorithm is developed on the basis of a detailed study, systematization and processing of data both on safety and on the efficiency of systems and structures, ensuring the delivery of irrigation water of the required quality and in sufficient quantity from a water source to the field.

OCCURRENCE OF THE RISKS FOR DEVELOPMENT OF RESPIRATORY DISEASES IN CHILDREN EXPOSED TO THE CHEMICAL FACTORS OF THE EXPOSURE OF ALUMINA REFINERY- ASSOCIATED BUSINESS ACTIVITY

2019 ◽  
pp. 42-47 ◽  
Author(s):  
M.A. Zemlianova ◽  
I.V. Tikhonova
Keyword(s):  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Inflammatory Diseases ◽  
Allergic Inflammation ◽  
Respiratory Morbidity ◽  
Upper Respiratory Tract ◽  
Negative Effects ◽  
Wide Range ◽  
Chemical Factors ◽  
Chronic Lymphoproliferative Diseases

Alumina refineries are among the leading sources of atmospheric air pollution with a wide range of pollutants hazardous to human respiratory organs. It is relevant to study and evaluate the occurrence of the risks for development of respiratory diseases in children living in the area affected by the emission components of an alumina refinery. We assessed air quality of the area under observation and comparison according to monitoring observations, risk of non-carcinogenic effects from the respiratory organs. The content of chemicals in the blood and urine adequate to risk factors was quantified. The structure of individual groups of respiratory diseases was analyzed. The causal relationships of violations of laboratory parameters with an increased content of chemicals in biological media were evaluated. It was found that an aerogenic exposure of chemical pollutants is formed on the territory with the production of metallurgical alumina. It determines the risk for development of respiratory diseases, exceeding an acceptable level up to 49.9 times. In the exposed children, the content of manganese, chromium, nickel, copper, xylenes, formaldehyde and aluminum, fluoride ion in the urine was increased to 4.2 times in relation to the indices in the comparison group. A high level of additional respiratory morbidity(1.8 times) was revealed. Chronic lymphoproliferative diseases of the nasopharynx and inflammatory diseases of the upper respiratory tract (up to 6.6 times more often), inflammatory diseases with a predominance of the mechanism of allergic inflammation ( up to 2.1 times more often)are more often detected in the framework of the respiratory diseases. Negative effects on the part of the respiratory system in the form of activation of antioxidant processes, the development of an inflammatory reaction, local, general and specific sensitization of the respiratory tract were established. It confirms the occurrence of the risks for the development of respiratory diseases in children in the exposure area of the chemical factors of alumina refinery-associated economic activity.

The chemistry of stabilized clusters

1982 ◽  
Vol 308 (1501) ◽  
pp. 27-34 ◽  
Keyword(s):  
Electron Donor ◽  
Organic Molecules ◽  
Metal Cluster ◽  
Organic Substrates ◽  
Insertion Reactions ◽  
Donor Ligand ◽  
Small Organic Molecules ◽  
Wide Range ◽  
Metal Metal ◽  
High Yields

Studies of the chemistry of metal cluster complexes and, in particular, their reactions with small organic molecules, have been confined to relatively few systems. Among the reasons for this are: (i) not many clusters are easily synthesized in high yields; (ii) their reactions often give a multitude of products that are difficult to separate and characterize; (iii) the conditions required to bring about reactions often lead to fragmentation of the cluster into lower nuclearity (often mononuclear) species. One cluster whose chemistry has been extensively studied is [Os 3 H 2 (CO) 10 ]. This can be synthesized in high yields from [Os 3 (CO) 12 ] + H 2 (Knox et al. 1975) and reacts readily under mild conditions with a wide range of electron-donor molecules by virtue of its coordinative unsaturation (Shapley et al. 1975; Deeming & Hasso 1976; Adams & Golembeski 1979). Formally, one may consider that a metal—metal double bond is present, which is reduced to a single bond on coordination of an additional two-electron donor ligand such as an organophosphine. The presence of metal—hydrogen bonds in this cluster and the cluster’s ability to coordinate organic substrates enable it to undergo a wide variety of insertion reactions, leading to products that may be regarded as intermediates in the reduction of organic molecules by clusters (Deeming & Hasso 1975; Keister & Shapley 1975).

scholarly journals Newly discovered Asgard archaea Hermodarchaeota potentially degrade alkanes and aromatics via alkyl/benzyl-succinate synthase and benzoyl-CoA pathway

2021 ◽  
Author(s):  
Jia-Wei Zhang ◽  
Hong-Po Dong ◽  
Li-Jun Hou ◽  
Yang Liu ◽  
Ya-Fei Ou ◽  
...  
Keyword(s):  
Nitrate Reduction ◽  
Coenzyme A ◽  
Organic Substrates ◽  
Mangrove Sediments ◽  
Sulfate Reducing ◽  
Sequence Read Archive ◽  
Wide Range ◽  
Genes Encoding ◽  
Sediment Carbon ◽  
Reducing Bacteria

AbstractAsgard archaea are widely distributed in anaerobic environments. Previous studies revealed the potential capability of Asgard archaea to utilize various organic substrates including proteins, carbohydrates, fatty acids, amino acids and hydrocarbons, suggesting that Asgard archaea play an important role in sediment carbon cycling. Here, we describe a previously unrecognized archaeal phylum, Hermodarchaeota, affiliated with the Asgard superphylum. The genomes of these archaea were recovered from metagenomes generated from mangrove sediments, and were found to encode alkyl/benzyl-succinate synthases and their activating enzymes that are similar to those identified in alkane-degrading sulfate-reducing bacteria. Hermodarchaeota also encode enzymes potentially involved in alkyl-coenzyme A and benzoyl-coenzyme A oxidation, the Wood–Ljungdahl pathway and nitrate reduction. These results indicate that members of this phylum have the potential to strictly anaerobically degrade alkanes and aromatic compounds, coupling the reduction of nitrate. By screening Sequence Read Archive, additional genes encoding 16S rRNA and alkyl/benzyl-succinate synthases analogous to those in Hermodarchaeota were identified in metagenomic datasets from a wide range of marine and freshwater sediments. These findings suggest that Asgard archaea capable of degrading alkanes and aromatics via formation of alkyl/benzyl-substituted succinates are ubiquitous in sediments.

scholarly journals Inositol phosphates: health implications, methods of analysis, and occurrence in plant foods

2018 ◽  
Vol 1 ◽  
Author(s):  
Quynh H. Duong ◽  
Karen G. Lapsley ◽  
Ronald B. Pegg
Keyword(s):  
Inositol Phosphates ◽  
Negative Effects ◽  
Plant Foods ◽  
Plant Seeds ◽  
Cell Functions ◽  
Wide Range ◽  
Multiple Cell ◽  
The Relationship

Inositol phosphates (InsPs), especially myo-inositol hexakisphosphate (InsP6), are important binders of phosphorus and minerals in plant seeds. However, they have long been considered as anti-nutritional components of plant foods due to their possible negative effects on the absorption of minerals and proteins in mammals. On the other hand, recent findings have found InsPs to be ubiquitous in eukaryote cells and actively participating in multiple cell functions. In vivo and in vitro studies have also documented the preventive potential of these compounds against the development of a wide range of diseases. In light of these findings, interest in the relationship between these compounds and human health has been renewed. It is suggested that the interactions of InsPs with other nutrients in the gut are complex, that the absorption of dietary InsPs might be implied but is not certain, and that the disease fighting capabilities of InsPs hold both promises and limitations. At the same time, the analysis of these compounds in foods and biological samples still faces many challenges, calling for more advanced modification and developments in the future.

scholarly journals Application of the C-S-H Phase Nucleating Agents to Improve the Performance of Sustainable Concrete Composites Containing Fly Ash for Use in the Precast Concrete Industry

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6514
Author(s):  
Grzegorz Ludwik Golewski ◽  
Bartosz Szostak
Keyword(s):  
Fly Ash ◽  
Industrial Waste ◽  
Precast Concrete ◽  
High Strength ◽  
Nucleating Agents ◽  
Negative Effects ◽  
Sustainable Concrete ◽  
Wide Range ◽  
Time Periods ◽  
Positive Effect

Siliceous fly ash (FA) is the main additive to currently produced concretes. The utilization of this industrial waste carries an evident pro-ecological factor. In addition, such actions have a positive effect on the structure and mechanical parameters of mature concrete. Unfortunately, the problem of using FA as a Portland cement replacement is that it significantly reduces the performance of concretes in the early stages of their curing. This limits the possibility of using this type of concrete, e.g., in prefabrication, where it is required to obtain high-strength composites after short periods of curing. In order to minimize these negative effects, this research was undertaken to increase the early strength of concretes with FA through the application of a specifically formulated chemical nano-admixture (NA) in the form of seeds of the C-S-H phase. The NA was used to accelerate the strength growth in concretes. Therefore, this paper presents results of tests of modified concretes both with the addition of FA and with innovative NA. The analyses were carried out based on the results of the macroscopic and microstructural tests in five time periods, i.e., after 4, 8, 12, 24 and 72 h. The results of tests carried out with the use of NA clearly indicate the possibility of using FA in a wide range of management areas in sustainable concrete prefabrication.

scholarly journals Transgenerational fitness effects of lifespan extension by dietary restriction in Caenorhabditis elegans

2021 ◽  
Vol 288 (1950) ◽  
Author(s):  
Edward R. Ivimey-Cook ◽  
Kris Sales ◽  
Hanne Carlsson ◽  
Simone Immler ◽  
Tracey Chapman ◽  
...  
Keyword(s):  
Caenorhabditis Elegans ◽  
Dietary Restriction ◽  
Mortality Risk ◽  
Lifespan Extension ◽  
Dietary Interventions ◽  
Negative Effects ◽  
Trade Offs ◽  
Wide Range ◽  
Broad Variety

Dietary restriction (DR) increases lifespan in a broad variety of organisms and improves health in humans. However, long-term transgenerational consequences of dietary interventions are poorly understood. Here, we investigated the effect of DR by temporary fasting (TF) on mortality risk, age-specific reproduction and fitness across three generations of descendants in Caenorhabditis elegans . We show that while TF robustly reduces mortality risk and improves late-life reproduction of the individuals subject to TF (P 0 ), it has a wide range of both positive and negative effects on their descendants (F 1 –F 3 ). Remarkably, great-grandparental exposure to TF in early life reduces fitness and increases mortality risk of F 3 descendants to such an extent that TF no longer promotes a lifespan extension. These findings reveal that transgenerational trade-offs accompany the instant benefits of DR, underscoring the need to consider fitness of future generations in pursuit of healthy ageing.

UN targeted sanctions datasets (1991–2013)

2018 ◽  
Vol 55 (3) ◽  
pp. 404-412 ◽  
Author(s):  
Thomas J Biersteker ◽  
Sue E Eckert ◽  
Marcos Tourinho ◽  
Zuzana Hudáková
Keyword(s):  
Cold War ◽  
Policy Instruments ◽  
Unintended Consequences ◽  
Negative Effects ◽  
Target Populations ◽  
Wide Range ◽  
Corporate Entity ◽  
Un Security Council ◽  
The Cold War ◽  
Quantitative And Qualitative Methods

Targeted sanctions are increasingly used by the United Nations (UN) Security Council to address major challenges to international peace and security. Unlike other sanctions, those imposed by the UN are universally binding and relied upon as a basis for legitimating both unilateral and regional sanctions measures. Encompassing a wide range of individual, diplomatic, financial, and sectoral measures, targeted sanctions allow senders to target a specific individual, corporate entity, region, or sector, helping to minimize the negative effects of sanctions on wider populations. This article introduces the Targeted Sanctions Consortium (TSC) quantitative and qualitative datasets, which encompass all UN targeted sanctions imposed between 1991 and 2013, or 23 different country regimes broken into 63 case episodes for comparative analysis. Adding to existing datasets on sanctions (HSE, TIES), these new, closely interrelated datasets enable scholars using both quantitative and qualitative methods to: (1) differentiate among different purposes, types of sanctions, and target populations, (2) assess the scope of different combinations of targeted measures, (3) access extensive details about UN sanctions applied since the end of the Cold War, and (4) analyze changing dynamics within sanctions regimes over time in ways other datasets do not. The two TSC datasets assess UN targeted sanctions as effective 22% of the time and describe major aspects of UN targeted sanctions regimes, including the types of sanctions, their purposes and targets, impacts, relationships with other institutions, sanctions regimes, and policy instruments, mechanisms of coping and evasion, and unintended consequences.

Germination Ecology of Two Australian Populations of African turnipweed (Sisymbrium thellungii)

Weed Science ◽  
2018 ◽  
Vol 66 (6) ◽  
pp. 752-757 ◽  
Author(s):  
Gulshan Mahajan ◽  
Amar Matloob ◽  
Michael Walsh ◽  
Bhagirath S. Chauhan
Keyword(s):  
Seed Germination ◽  
Management Strategies ◽  
Soil Surface ◽  
Wheat Crop ◽  
Burial Depth ◽  
Negative Effects ◽  
Wide Range ◽  
Water Ph ◽  
Winter Crops ◽  
Residue Study

AbstractAfrican turnipweed (Sisymbrium thellungiiO. E.Schulz) is an emerging problematic broadleaf weed of the northern grain region of Australia. Laboratory experiments were conducted to evaluate the effects of temperature, light, salinity, pH, seed burial depth, and the amount of wheat crop residue on germination and emergence of two AustralianS. thellungiiweed populations (population C, cropped area; population F, fence line). Both populations behaved similarly across different environmental conditions, except in the residue study. Although the seeds of both populations ofS. thellungiicould germinate under complete darkness, germination was best (~95%) under light/dark conditions at the 20/10 C temperature regime. Both populations ofS. thellungiigerminated over a wide range of day/night temperatures (15/5, 20/10, 25/15, and 30/20 C). Osmotic stress had negative effects on germination, with 54% seeds (averaged over populations) able to germinate at −0.1MPa. Complete germination inhibition for both populations was observed at −0.8MPa osmotic potential. Both populations germinated at sodium chloride (NaCl) concentrations ranging from 50 to 100 mM, beyond which germination was completely inhibited. There were substantial reductions in seed germination, 32% (averaged over populations) under highly acidic conditions (pH 4.0) as compared with the control (water: pH 6.4). Seed germination of both populations on the soil surface was 77%, and no seedlings emerged from a burial depth of 1 cm. The addition of 6 Mg ha−1of wheat (Triticum aestivumL.) residue reduced the emergence of the C and F populations ofS. thellungiiby 75% and 64%, respectively, as compared with the control (no residue). Information gathered from this study provides a better understanding of the factors favorable for germination and emergence ofS. thellungii, which will aid in developing management strategies in winter crops, especially wheat, barley (Hordeum vulgareL.), and chick pea (Cicer arietinumL.).

scholarly journals Risiko Online Pada Remaja dan Pendidikan Literasi Media Baru

2018 ◽  
Vol 2 (1) ◽  
pp. 13
Author(s):  
Amia Luthfia
Keyword(s):  
New Media ◽  
Media Literacy ◽  
Literacy Education ◽  
Negative Effects ◽  
Literacy Curriculum ◽  
Wide Range ◽  
On Line ◽  
New Media Literacy ◽  
Search For Information

Teenager aged 10-19 years is the digital native generation and thetj are connected with the virtual world almost every time. Online activities they do, among others, are connected through social media, search for information on various websites, downloading music, watching movies via YouTube, read the news, play on-line games, and etc. Teens' on-line activity behind it has a variety of risks and should be examined together with any kind of on-line risks experienced by adolescents as a first step in order to minimize the negative effects that rcould occur. This article contains a study of the conceptualization of on-line risk, scope and classification of on-line risk; featuring a wide range of research<br />011 the influence of social environment on the risk of on-line teens; and attempts to deal with the risk of negative media that hit young people through new media literacy education. Media literacy curriculum that already exist.&gt;hould be adapted to the characteristics of new media. At its core, the new media literacy should include: (1) media literacy; (2) d igital technologtj literacy; (3) civil and social respol?sibility; and ( 4) imagination and creativih;.

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