scholarly journals The Role of Polymer Structure in Formation of Various Nano- and Microstructural Materials: 30 Years of Research in the Laboratory of Nano- and Microstructural Materials at the Centre of Polymer and Carbon Materials PAS

Polymers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 2892
Author(s):  
Natalia Oleszko-Torbus ◽  
Barbara Mendrek ◽  
Agnieszka Kowalczuk ◽  
Wojciech Wałach ◽  
Barbara Trzebicka ◽  
...  
Keyword(s):  
Carbon Materials ◽  
Biologically Active ◽  
Linear Polymers ◽  
Controlled Polymerization ◽  
Physiochemical Properties ◽  
Wide Range ◽  
Methacrylate Monomers ◽  
Academy Of Sciences ◽  
Active Substances

The review summarizes the research carried out in the Laboratory of Nano- and Microstructural Materials at the Centre of Polymer and Carbon Materials, Polish Academy of Sciences (CMPW PAS). Studies carried out for many years under the guidance of Professor Andrzej Dworak led to the development and exploration of the mechanisms of oxirane and cyclic imine polymerization and controlled radical polymerization of methacrylate monomers. Based on that knowledge, within the last three decades, macromolecules with the desired composition, molar mass and topology were obtained and investigated. The ability to control the structure of the synthesized polymers turned out to be important, as it provided a way to tailor the physiochemical properties of the materials to their specific uses. Many linear polymers and copolymers as well as macromolecules with branched, star, dendritic and hyperbranched architectures were synthesized. Thanks to the applied controlled polymerization techniques, it was possible to obtain hydrophilic, hydrophobic, amphiphilic and stimulus-sensitive polymers. These tailor-made polymers with controlled properties were used for the construction of various types of materials, primarily on the micro- and nanoscales, with a wide range of possible applications, mainly in biomedicine. The diverse topology of polymers, and thus their properties, made it possible to obtain various types of polymeric nanostructures and use them as nanocarriers by encapsulation of biologically active substances. Additionally, polymer layers were obtained with features useful in medicine, particularly regenerative medicine and tissue engineering.

The content of decenoic acids in drone brood preparations and combined preparations based on it

Biomics ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 389-393
Author(s):  
D.V. Mitrofanov ◽  
N.V. Budnikova
Keyword(s):  
Royal Jelly ◽  
Storage Conditions ◽  
Water Soluble ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Strict Adherence ◽  
Drone Brood ◽  
Wide Range ◽  
Active Substances ◽  
Melanin Complex

The drone brood contains a large number of substances with antioxidant activity. These substances require stabilization and strict adherence to storage conditions. Among these substances are unique decenoic acids, the content of which is an indicator of the quality of drone brood and products based on it. The ability of drone brood to reduce the manifestations of oxidative stress is shown. There are dietary supplements for food and drugs based on drone brood, which are used for a wide range of diseases. Together with drone brood, chitosan-containing products, propolis, royal jelly can be used. They enrich the composition with their own biologically active substances and affect the preservation of the biologically active substances of the drone brood. Promising are the products containing, in addition to the drone brood, a chitin-chitosan-melanin complex from bees, propolis, royal jelly. The chitin-chitosan-melanin complex in the amount of 5% in the composition of the adsorbent practically does not affect the preservation of decenic acids, while in the amount of 2% and 10% it somewhat worsens. The acid-soluble and water-soluble chitosan of marine crustaceans significantly worsens the preservation of decenoic acids in the product. Drone brood with royal jelly demonstrates a rather high content of decenoic acids. When propolis is introduced into the composition of the product, the content of decenoic acids increases according to the content of propolis.

CRITERIA FOR SELECTION OF PREPARATIONS IN THE DEVELOPMENT OF SORPTION-DETOXIFYING COMPLEXES FOR AGRICULTURAL ANIMALS

2018 ◽  
Vol 1 (2) ◽  
pp. 94-100
Author(s):  
L.L. Zakharova ◽  
◽  
G.A. Zhorov ◽  
V.I. Dorozhkin ◽  
◽  
...  
Keyword(s):  
Chemical Nature ◽  
Negative Impact ◽  
Physiological State ◽  
Animal Husbandry ◽  
Biologically Active ◽  
Combined Pollution ◽  
Wide Range ◽  
Active Substances ◽  
Criteria For Selection ◽  
Selection Of

Negative impact on the environment as a result of economic activity of man increasingly becomes the character of combined pollution of ecotoxicants, including xenobiotics of radiation and chemical nature. In animal husbandry in ecologically unfavorable regions, sorbtion-detoxication technologies based on the complex application of bioprotective substances of different origin are used to reduce the intake and accumulation of xenobiotics, to normalize the physiological state of animals and to obtain safe products. It is necessary to observe certain principles ensuring compatibility of components, a wide range of bioprotective action, efficiency and safety at their use in developing the compositions of such sorption-detoxifying complexes. The article substantiates the criteria that should be followed in creating sorption-detoxifying complexes and presents groups of drugs with different mechanisms of action (sorbents, antioxidants, immunomodulators, adaptogens and other biologically active substances) for inclusion in the formulations of combined compositions.

scholarly journals Assessment of Monoterpene Components in Wild Rose Petals Extract

2020 ◽  
Vol 21 (2) ◽  
pp. 254-262
Author(s):  
Koval Inna
Keyword(s):  
Gas Chromatography ◽  
Steam Distillation ◽  
Botanical Garden ◽  
Component Composition ◽  
Biologically Active ◽  
National Academy Of Sciences ◽  
Volatile Organic ◽  
Rose Petals ◽  
Academy Of Sciences ◽  
Active Substances

The content, component composition, and main directions of the use of monoterpenes of wild rose petals compounds are considered in the research. The study on six wild rose species was carried out in the collection of M.M. Gryshko National Botanical Garden of the National Academy of Sciences of Ukraine. Volatile organic compounds were isolated by steam distillation, and their determination was performed by means of gas chromatography. R. rugosa petals contained the highest number of monoterpenoids, while R. canina petals – the lowest. In our research twentyone different (acyclic, monocyclic, bicyclic) monoterpenoids were identified, including alcohols, aldehydes, ethers, and ketones. All groups of monoterpenoids are biologically active substances and have a significant effect on the aroma of the studied plants.

scholarly journals Рукописное наследие татарских ученых в фондах Института востоковедения Академии Наук Республики Узбекистан

Islamology ◽  
2019 ◽  
Vol 9 (1-2) ◽  
pp. 195
Author(s):  
Saidakbar Mukhammadaminov
Keyword(s):  
Wide Range ◽  
The World ◽  
The Creation ◽  
Oriental Studies ◽  
Academy Of Sciences

The article is dedicated to the manuscript heritage of Tatar scholars held in Abu Rayhan Beruni Institute of Oriental Studies of the Academy of Sciences of Uzbekistan, one of the richest manuscript repositories in the world. Works of manuscripts of Tatar theologians such as Abdurahim Utyz-Imyani, Abu al-Nasr Qursawi, Shihabaddin Mardjani, and Hisam al-Din b. Sharaf al- Din al-Bulgari, Kamal al-Din b. Siraj al-Din al-Uribfori al-Kazani, ̒Ayn al-Din b. Jalal al-Din al-Kazani, Abu al-Sharaf Husain b. Abu Umar al- Bulgari, Muhammad Latif b. Abdulislam al-Bulgari are analyzed. Based on a review of the manuscripts, it is established that some of them have not yet been catalogued. It is argued that the works of Tatar scholars were mainly devoted to religious subjects. The role of Tatar scholars in the creation of commentaries and works on legal, medical and Sufi terms is analyzed in order to make the works accessible to a wide range of people seeking knowledge.

Immune cells of the epithelial ovarian cancer microenvironment

2021 ◽  
pp. 67-78
Author(s):  
Varvara Nikolaevna Zhurman ◽  
Natalia Gennadevna Plekhova ◽  
Ekaterina Valeryevna Eliseeva
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Immune Cells ◽  
Ovarian Tumor ◽  
Biologically Active ◽  
Cancer Microenvironment ◽  
Review Of The Literature ◽  
Prognostic Role ◽  
Active Substances

The article is a review of the literature, which analyzes the data on the role of cells of the immune system, cytokines and other biologically active substances secreted by them in the interstitial space of an ovarian tumor. The emphasis is made on the mechanism of realization by immune cells of the stimulating and suppressing action on the development of the tumor. Considerable attention is paid to the prognostic role of immune cells in the development of epithelial ovarian cancer.

Carbon Materials for Immobilization of Biologically Active Substances

2020 ◽  
Vol 836 ◽  
pp. 52-57
Author(s):  
O.V. Denisova ◽  
I.I. Rastvorova
Keyword(s):  
Carbon Fibers ◽  
Carbon Materials ◽  
Atomic Layer ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Layer Deposition ◽  
Atomic Layer Deposition Method ◽  
Activity Of Enzymes ◽  
Surface Modified ◽  
Active Substances

The paper considers applications of carbon materials as carriers of biologically active substances. The atomic layer deposition method allowed chemically synthesizing surface-modified composite materials based on graphite and carbon fibers, which maximally preserved the activity of enzymes and biologically active substances. It is shown that the activity of a biologically active substance depends on the chemical composition and state of the surface of carbon-based carriers.

SWEET SAWBERRY (Comarum Palustre L.) IN MEDICAL PRACTICE (literature review)

2020 ◽  
Vol 5 (4) ◽  
pp. 66-70 ◽  
Author(s):  
V. Platonov ◽  
Aleksandr Hadarcev ◽  
Elena Belyaeva
Keyword(s):  
Chemical Composition ◽  
Medical Practice ◽  
Clinical Medicine ◽  
Biologically Active ◽  
General Description ◽  
Plant Origin ◽  
Comarum Palustre ◽  
Practice Literature ◽  
Active Substances

The review substantiates the use of biologically active substances of plant origin, derived from marsh saber, common on the territory of Russia – in various sections of clinical medicine. The General description and zones of its distribution, possibilities of extraction of Sabel-nick rhizomes are given. The chemical composition was charac-terized and the role of proanthocyanidins in the anti-inflammatory effects of sabelnik was clarified. The possibility of obtaining various medicinal forms of drugs from the rhizomes of sabelnik is shown. A well-known range of applications in medical practice for lesions of the musculoskeletal system, arthrosis and arthritis, nephropathy, after transurethral resection of the prostate, etc.

scholarly journals Biologically Active Substances of Siberian Medical Plants in Functional Wgey-Based Drinks

2019 ◽  
Vol 49 (1) ◽  
pp. 14-22
Author(s):  
Светлана Иванова ◽  
Svetlana Ivanova ◽  
Ирина Милентьева ◽  
Irina Milenteva ◽  
Людмила Асякина ◽  
...  
Keyword(s):  
Callus Cultures ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Rhodiola Rosea ◽  
Plant Materials ◽  
Rhaponticum Carthamoides ◽  
Wide Range ◽  
Mountain Ash ◽  
Active Substances ◽  
Mineral Base

The use of infusions and extracts from domestic plant materials is a promising direction in the development of functional beverages since they contain a wide range of substances of various pharmacological properties. Drinks fortified with physiologically active natural components maintain a certain level of this content in human body. They can have a healing or prophylactic effect. However, there is a lack of technologies for the effective production of biologically active substances from plant materials. Moreover, the development of cultivated botanical medicinal plant species remains quite poor. The present study features the qualitative and quantitative composition of biologically active substances of medicinal plants that are endemics of Siberia. They are Rhodiola rosea (Rhodiola rosea L.) and maral root (Rhaponticum carthamoides). The paper introduces a method for increasing their biosynthetic activity. An experiment helped to select a composition of the nutrient medium for the cultivation of callus cultures of Rhodiola rosea (Rhodiola rosea L.) and maral root (Rhaponticum carthamoides) in vitro, which contributed to an increase in the biosynthesis of biologically active substances. For callus cultures of Rhodiola Rosea (line R.r-1k) the following composition was used: mineral base – MS; sucrose – 30 g; inositol – 100 mg; thiamine – 1.0 mg; pyridoxine – 1.0 mg; Ca-panthetonate – 10 mg; kinetin – 0.05 g; naphthyl acetic acid – 0.1 g; 2.4-D – 0.5. For callus cultures of maral root (line R.c -2k): mineral base – SH; sucrose – 30 g; inositol – 100 mg; thiamine – 5.0 mg; pyridoxine – 0.5 mg; nicotinic acid – 5.0 mg; kinetin – 0.1 g; indoleacetic acid – 1.0 g. The authors developed a technology for the production of functional whey-based tonic drink fortified with extract of carotenoids isolated from the fruits of mountain ash and the extract of biologically active substances Rhodiola rosea and maral root. The presence of biologically active substances in the plant and medicinal raw materials gives the drink antioxidant and bactericidal properties, as well as helps to raise the overall state of the organizm and strengthen the immune system.

scholarly journals Results of studies of the influence of phytopreparations on cows and calfs

2021 ◽  
Vol 282 ◽  
pp. 04003
Author(s):  
V.S. Kozyr ◽  
P.P. Antonenko ◽  
N.I. Suslova ◽  
R.V. Mylostyvyi
Keyword(s):  
Reproductive Function ◽  
Biologically Active ◽  
Pharmacological Effects ◽  
Cattle Breeding ◽  
Biochemical System ◽  
Efficient Management ◽  
Wide Range ◽  
Newborn Calves ◽  
Young Cattle ◽  
Active Substances

Purpose. To establish the influence of the “Phytochol”, “Phytopunk” and “Gastroacide” phytopreparations developed by the authors on the reproductive function of cows, resistance and safety for calves. Methods. Biological, biochemical, hematological, immunological, analytical, biometric, zootechnical. Results. It has been established that in homeopathic doses, the studied drugs are non-toxic, have a wide range of pharmacological effects and contain biologically active substances that have strengthening, tonic properties, metabolism normalizing in the “cow-calf” biochemical system. Conclusions. To normalize the reproductive function of cows, it is advisable to use “Phytochol”and “Phytopunk”. The resistance of newborn calves is strengthened by feeding them “Phytopunk” and “Gastroacide”. The productivity of young cattle can be increased by introducing the drug “Phytochol” into the ration. The use of phytopreparations “Phytopunk”, “Phytochol” in homeopathic doses in cattle breeding contributes to a more efficient management of the industry.

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