What is the placebo effect?

2021 ◽  
pp. 64-67
Author(s):  
Georgiy Rubenovich Petrosyan
Keyword(s):  
Placebo Effect ◽  
Mental State ◽  
18Th Century ◽  
Emotional Perception ◽  
Medicinal Substances ◽  
American Physician ◽  
The Cost ◽  
Vital Forces ◽  
First Time ◽  
Positive Effect

For the first time, the placebo effect was described in 1955 by the American physician Henry Beecher, who found that about a third of patients recover as a result of the use of sugar pills that do not contain any active medicinal substances. The first mentions of such drugs date back to the 18th century; at that time they meant "fake" drugs containing indifferent substances in their composition. It is believed that the placebo effect is associated with a person's psycho-emotional perception of this drug as a means of salvation, belief in its effectiveness and efficacy, and the desire to recover. Against this background, the maximum mobilization of vital forces occurs, the processes of regeneration are switched on, and the physical and mental state of the patient is normalized. An interesting fact is that the severity of the placebo effect can be significantly affected by the cost of the drug (the higher it is, the better the drug "helps") and even its appearance. For instance, yellow pills are very effective in treating depression, green pills help reduce feelings of anxiety, and white pills assist in treating stomach ulcers. In addition, taking two pills has a greater positive effect than taking one.

SKIN PRODUCTS OF YOUNG MALE MINK AND ECONOMIC EFFECT WHEN USING THE VITAZAR PREPARATION

2021 ◽  
pp. 123-129
Author(s):  
M.YU. LYUBIMOVA ◽  
◽  
N.A. BALAKIREV ◽  
S.V. POZYABIN
Keyword(s):  
Fatty Acids ◽  
Economic Effect ◽  
Antioxidant Properties ◽  
Young Male ◽  
Live Weight ◽  
Optimal Dose ◽  
The Cost ◽  
Fat Soluble Vitamins ◽  
First Time ◽  
Positive Effect

The Vitazar preparation has a rich natural composition and antioxidant properties due to the high content of fat-soluble vitamins – A, D, E, polyunsaturated fatty acids – linoleic, linolenic, oleic, palmitic, as well as trace elements Ca and K, etc. To study the preparation effects on young male minks, animals of the standard black breed of Scandinavian selection were chosen by origin, live weight and age using the method of analogous groups. A total of 128 males participated in the experiment – 32 heads in each group. The first group of minks was the control one. In three experimental groups, Vitazar was added to the general household ration with a different dose of 1.0.2.0.3.0 ml/head with a frequency of three times a week. The preparation was given during two summer months – July and August. During the experiment, the minks were weighed at the beginning of each month. After slaughter and primary processing, the skins were sorted in accordance with GOST 27769–88.According to the data obtained, Vitazar has a positive effect on the live weight and skin production of young minks. The drug in the diet of males at a dose of 3.0 ml/head contributes to an increase in live weight by 191 g, the skin size by 0.6 dm2, the proportion of defect-free skins by 8.0% and the quality indicators by 4.0%. The optimal dose of the preparation was found to be 3.0 ml/head.The use of Vitazar in the optimal dose in the diet of male minks increased the cost of one skin by 63.3 rubles. Thу “Vitazar” preparation was studied on young minks for the first time.

An Evaluation of Provincial Macroeconomic Performance in Vietnam

2017 ◽  
pp. 34-47
Author(s):  
Hoi Le Quoc ◽  
Nam Pham Xuan ◽  
Tuan Nguyen Anh
Keyword(s):  
Development Strategy ◽  
Institutional Transformation ◽  
Economic Indicators ◽  
Macroeconomic Performance ◽  
Economic Development Strategy ◽  
Socio Economic Development ◽  
The Cost ◽  
Development Objectives ◽  
First Time

The study was targeted at developing a methodology for constructing a macroeconomic performance index at a provincial level for the first time in Vietnam based on 4 groups of measurements: (i) Economic indicators; (ii) oriented economic indicators; (iii) socio-economic indicators; and (iv) economic - social – institutional indicators. Applying the methodology to the 2011 - 2015 empirical data of all provinces in Vietnam, the research shows that the socio-economic development strategy implemented by those provinces did not provide balanced outcomes between growth and social objectives, sustainability and inclusiveness. Many provinces focused on economic growth at the cost of structural change, equality and institutional transformation. In contrast, many provinces were successful in improving equality but not growth. Those facts threaten the long-term development objectives of the provinces.

scholarly journals Autism Tsunami: the Impact of Rising Prevalence on the Societal Cost of Autism in the United States

2021 ◽  
Author(s):  
Mark Blaxill ◽  
Toby Rogers ◽  
Cynthia Nevison
Keyword(s):  
Forecast Model ◽  
The United States ◽  
Population Projections ◽  
Base Case ◽  
Prevention Strategies ◽  
Total Base ◽  
Cost Categories ◽  
The Cost ◽  
The Impact ◽  
First Time

AbstractThe cost of ASD in the U.S. is estimated using a forecast model that for the first time accounts for the true historical increase in ASD. Model inputs include ASD prevalence, census population projections, six cost categories, ten age brackets, inflation projections, and three future prevalence scenarios. Future ASD costs increase dramatically: total base-case costs of $223 (175–271) billion/year are estimated in 2020; $589 billion/year in 2030, $1.36 trillion/year in 2040, and $5.54 (4.29–6.78) trillion/year by 2060, with substantial potential savings through ASD prevention. Rising prevalence, the shift from child to adult-dominated costs, the transfer of costs from parents onto government, and the soaring total costs raise pressing policy questions and demand an urgent focus on prevention strategies.

scholarly journals A METHODOLOGY TO SUPPORT COMPANIES IN THE FIRST STEPS TOWARDS DE-MANUFACTURING

2021 ◽  
Vol 1 ◽  
pp. 131-140
Author(s):  
Federica Cappelletti ◽  
Marta Rossi ◽  
Michele Germani ◽  
Mohammad Shadman Hanif
Keyword(s):  
Environmental Impact ◽  
End Of Life ◽  
Design Stage ◽  
Life Strategies ◽  
Disassembly Sequence ◽  
The Status ◽  
The Cost ◽  
Technical Solutions ◽  
First Time ◽  
Complex Activities

AbstractDe-manufacturing and re-manufacturing are fundamental technical solutions to efficiently recover value from post-use products. Disassembly in one of the most complex activities in de-manufacturing because i) the more manual it is the higher is its cost, ii) disassembly times are variable due to uncertainty of conditions of products reaching their EoL, and iii) because it is necessary to know which components to disassemble to balance the cost of disassembly. The paper proposes a methodology that finds ways of applications: it can be applied at the design stage to detect space for product design improvements, and it also represents a baseline from organizations approaching de-manufacturing for the first time. The methodology consists of four main steps, in which firstly targets components are identified, according to their environmental impact; secondly their disassembly sequence is qualitatively evaluated, and successively it is quantitatively determined via disassembly times, predicting also the status of the component at their End of Life. The aim of the methodology is reached at the fourth phase when alternative, eco-friendlier End of Life strategies are proposed, verified, and chosen.

A standardized terminology of spines in the order Siluriformes (Actinopterygii: Ostariophysi)

2021 ◽  
Author(s):  
Gustavo A Ballen ◽  
Mario C C De Pinna
Keyword(s):  
Comparative Anatomy ◽  
Appendicular Skeleton ◽  
Extensive Literature ◽  
Direct Examination ◽  
Dorsal Fin ◽  
Anatomical Nomenclature ◽  
Standardized Terminology ◽  
The Cost ◽  
First Time ◽  
Terminology System

Abstract A standardized terminology for the anatomy of pectoral- and dorsal-fin spines in the order Siluriformes is proposed based on an extensive literature review and direct examination of representatives of the order. The adult anatomy of the spines is described in detail. Terminology of various spine parts are reviewed and standardized, each term provided with a synonymic list organizing previous usage. Most of the structures treated have been recorded and named in the literature, but some are herein named for the first time. A quantitative approach is proposed for orienting decisions on name usage, aiming at minimizing differences between the terminology proposed and the vast amount of pre-existing literature, herein called the cost function. It is expected that this system will aid efforts in organizing the chaotic anatomical nomenclature of the appendicular skeleton in Siluriformes, and provide a solid basis for advances in comparative anatomy and nomenclature. The proposed terminology system has potential application on a number of fields that utilize information from catfish spines, ranging from taxonomy to phylogenetic systematics to paleontology and archaeology.

Empowering and Directive Leadership: The Cost of Changing Styles

2021 ◽  
pp. 227853372110083
Author(s):  
Smita Mukherjee ◽  
Zubin R. Mulla
Keyword(s):  
Laboratory Experiment ◽  
Leadership Styles ◽  
Leadership Style ◽  
Affective Commitment ◽  
Team Outcomes ◽  
History Of ◽  
Satisfaction With The Leader ◽  
The Cost ◽  
First Time

We examine the cost of leaders changing between empowering and directive leadership styles on team outcomes. In a laboratory experiment, we collected data from 240 participants in 80 teams. Confederates enacted different leadership styles and led teams of participants in performing a series of tasks. When leaders changed their style from directive to empowering, teams took time to respond in terms of higher satisfaction with leader and affective commitment. However, when leaders changed their style from empowering to directive, the deterioration of satisfaction with leader and reduction in affective commitment were immediate. Moreover, teams of leaders who had been consistently directive showed higher affective commitment as compared to teams of leaders who had a history of being empowering but later shifted to being directive. First time managers can get inputs on how they should enact their leadership style and be aware that switching between styles may impose long-term costs on the team’s affective commitment and satisfaction with the leader.

scholarly journals Wheat Bread with Grape Seeds Micropowder: Impact on Dough Rheology and Bread Properties

2020 ◽  
Vol 30 (1) ◽  
pp. 138-150
Author(s):  
Veronika Valková ◽  
Hana Ďúranová ◽  
Jana Štefániková ◽  
Michal Miškeje ◽  
Marián Tokár ◽  
...  
Keyword(s):  
Wheat Flour ◽  
Dough Rheology ◽  
Wheat Bread ◽  
Grape Seeds ◽  
Rheological Analysis ◽  
First Time ◽  
Positive Effect ◽  
Bread Properties ◽  
Electronic Eye ◽  
Different Levels

AbstractThe current study was designed to enhance the functionality of white bread by replacement of wheat flour with different levels (1%, 2%, 5%, and 8%) of grape seeds micropowder (GSMP) with nanosized particles (10 µm). Chemical composition of GSMP, volume and sensory attributes, evaluated with the panel of evaluators and an electronic nose (e-nose) and an electronic eye (e-eye) were investigated in the tested breads. It has been found out that GSMP contained appreciable amounts of flavonoids including catechin, epicatechin, gallic acid and minerals especially, Ca, K and Mg. The data from rheological analysis showed that the addition of GSMP (mainly at 5% and 8% levels) to the wheat flour had a positive effect on dough manifesting with rheology by increased dough stability. The volume of the experimental breads (above 1% concentration) was demonstrably declined (P < 0.0001) in comparison with the control bread. Sensory rating revealed that the bread fortified with 1% GSMP was judged by the consumer panelists as the most acceptable with the highest scores for all quality attributes which was also confirmed by the data of e-nose and e-eye. Our results suggest for the first time that 1% GSMP addition appears to be a promising functional ingredient to improve bread with required qualitative and sensory properties.

scholarly journals An Optimized Mathematical Model for Items Supplies Planning of a Logistic System

2016 ◽  
Vol 10 (10) ◽  
pp. 133
Author(s):  
Mohammad Ali Nasiri Khalili ◽  
Mostafa Kafaei Razavi ◽  
Morteza Kafaee Razavi
Keyword(s):  
Mathematical Model ◽  
Mixed Integer ◽  
Logistics System ◽  
Proposed Model ◽  
Multiple Objective Decision Making ◽  
System Requirements ◽  
Purchasing Logistics ◽  
The Cost ◽  
The Mathematical Model ◽  
First Time

Items supplies planning of a logistic system is one of the major issue in operations research. In this article the aim is to determine how much of each item per month from each supplier logistics system requirements must be provided. To do this, a novel multi objective mixed integer programming mathematical model is offered for the first time. Since in logistics system, delivery on time is very important, the first objective is minimization of time in delivery on time costs (including lack and maintenance costs) and the cost of purchasing logistics system. The second objective function is minimization of the transportation supplier costs. Solving the mathematical model shows how to use the Multiple Objective Decision Making (MODM) can provide the ensuring policy and transportation logistics needed items. This model is solved with CPLEX and computational results show the effectiveness of the proposed model.

"Itzt kommen die Soldaten"

2019 ◽  
Author(s):  
Tilman Venzl
Keyword(s):  
Literary History ◽  
18Th Century ◽  
Military History ◽  
Form And Function ◽  
Social Structural ◽  
History Of ◽  
The Subject ◽  
And Function ◽  
The Military ◽  
First Time

In the 18th century, as many as 300 German-language plays were produced with the military and its contact and friction with civil society serving as focus of the dramatic events. The immense public interest these plays attracted feeds not least on the fundamental social structural change that was brought about by the establishment of standing armies. In his historico-cultural literary study, Tilman Venzl shows how these military dramas literarily depict complex social processes and discuss the new problems in an affirmative or critical manner. For the first time, the findings of the New Military History are comprehensively included in the literary history of the 18th century. Thus, the example of selected military dramas – including Lessing's Minna von Barnhelm and Lenz's Die Soldaten – reveals the entire range of variety characterizing the history of both form and function of the subject.

scholarly journals An Experiential Community Orientation to Improve Knowledge and Assess Resident Attitudes Toward Poor Patients

2013 ◽  
Vol 5 (1) ◽  
pp. 119-124 ◽  
Author(s):  
Erik A. Wallace ◽  
Julie E. Miller-Cribbs ◽  
F. Daniel Duffy
Keyword(s):  
Descriptive Analysis ◽  
Quality Health Care ◽  
Resident Attitudes ◽  
Community Orientation ◽  
Knowledge And Attitudes ◽  
Underserved Patients ◽  
Quality Health ◽  
Care Training ◽  
The Cost ◽  
Positive Effect

Abstract Background Future physicians may not be prepared for the challenges of caring for the growing population of poor patients in this country. Given the potential for a socioeconomic “gulf” between physicians and patients and the lack of curricula that address the specific needs of poor patients, resident knowledge about caring for this underserved population is low. Intervention We created a 2-day Resident Academy orientation, before the start of residency training, to improve community knowledge and address resident attitudes toward poor patients through team-based experiential activities. We collected demographic and satisfaction data through anonymous presurvey and postsurvey t tests, and descriptive analysis of the quantitative data were conducted. Qualitative comments from open-ended questions were reviewed, coded, and divided into themes. We also offer information on the cost and replicability of the Academy. Results Residents rated most components of the Academy as “very good” or “excellent.” Satisfaction scores were higher among residents in primary care training programs than among residents in nonprimary care programs for most Academy elements. Qualitative data demonstrated an overall positive effect on resident knowledge and attitudes about community resource availability for underserved patients, and the challenges of poor patients to access high-quality health care. Conclusions The Resident Academy orientation improved knowledge and attitudes of new residents before the start of residency, and residents were satisfied with the experience. The commitment of institutional leaders is essential for success.

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