Issues of safe correction of gastroduodenal symptoms during pregnancy

2022 ◽  
pp. 66-74
Author(s):  
Yuliya Yurievna Chebotareva ◽  
◽  
Elena Nikolaevna Veselova ◽  
Yuriy Alekseevich Petrov ◽  
◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Pregnant Women ◽  
Critical Analysis ◽  
Clinical Symptoms ◽  
Diagnosis And Treatment ◽  
First Line ◽  
Pregnancy And Childbirth ◽  
Study Evaluation ◽  
Complicated Course ◽  
Effect Of Treatment

Extragenital diseases make a great effect on the complicated course of pregnancy and childbirth. The lack of pregravidar preparation and somatic diagnostics lead to miscarriage, preeclampsia, and placental disorders. Therefore, the development of various algorithms for the management of pregnant women suffering from diseases of the gastrointestinal tract and the safe correction of various gastroduodenal symptoms, which is sometimes characteristic of the gestation period, are relevant. The purpose of the study: evaluation and critical analysis of modern data in the field of diagnosis and safe correction of various gastroduodenal symptoms during pregnancy. Materials and methods. Collection of modern Russian and foreign literature sources on the correction of gastroduodenal pathology during pregnancy, generalization and critical analysis of this problem. Results. Heartburn, constipation, flatulence are the most common complaints during pregnancy. The causes of their occurrence are physiological features during gestation, aimed at the most favorable gestation of the fetus. The first-line preparations are alginates created on the basis of alginic acid of brown alga. Antacids have a number of disadvantages. Proton pump inhibitors are prescribed extremely rarely and cautiously during pregnancy. In case of constipation in pregnant women, it is recommended to prescribe lactulose preparations together with defoamers. Prebiotics perfectly regulate the work of the intestine. The etiology, mechanisms of occurrence, clinical symptoms, differential diagnosis and treatment of intrahepatic cholestasis of pregnant women were analyzed. Its possible prognoses and risks for the mother and fetus, the possibilities of diagnosis and correction are determined. Diseases of the gastrointestinal tract in pregnant women cause difficulties in diagnosis and treatment. For the most optimal course of pregnancy, there are sufficiently effective gastroenterological drugs recommended so that the effect of treatment is maximized and the side effect is minimized.

scholarly journals Experience in managing a patient with a complicated course of SARS-COV-2 infection: early pulmonary rehabilitation and prevention of pulmonary fibrosis (clinical case)

2020 ◽  
Vol 43 (3) ◽  
pp. 365-372
Keyword(s):  
Lung Function ◽  
Large Scale ◽  
Clinical Case ◽  
Clinical Symptoms ◽  
Oral Anticoagulants ◽  
Diagnosis And Treatment ◽  
Complicated Course ◽  
Coronavirus Infection ◽  
Polymerase Chain ◽  
Virus Strains

Over the past two decades the world community has been shocked by the three largest coronavirus pandemics, each of which, despite the similarity of clinical symptoms in many aspects, has its own differences. This fact significantly complicates the diagnosis and treatment of new virus strains, which leads to a forced delay in early diagnosis and treatment of the disease, as well as the impossibility of suppressing the epidemic at the initial stages of its development. The article presents the clinical case of a complicated course of a new coronavirus infection – COVID-19 from the practice of a pulmonologist. There is data on the tactics of managing the patient until the visit to the pulmonologist. Minor changes are observed only in the auscultatory picture among physical data. Certain changes in laboratory and instrumental parameters are noted during the treatment of the patient. An important role in the diagnosis of the disease was played by the methods of enzyme immunoassay and polymerase chain reaction, as well as spiral computed tomography (SCT) of the chest, which made it possible to detect lesions, diagnose excessive consolidation (formation of pneumofibrosis) and its regression in dynamics against the background of active treatment. Spirometry made it possible to assess lung function over time. In the treatment were used drugs with anticoagulant and anti-fibrotic activity (new oral anticoagulants – apixaban (Eliquis®), a polyenzyme drug – Wobenzym® and enzyme – bovgialuronidase azoxymer (Longidaza®)), together with a set of antioxidant vitamins and minerals, and there was an improvement in lung function. The scientific community is carrying out a large-scale work to find new approaches in the treatment of coronavirus infection (COVID-19), however, the majority of the developed diagnostic and treatment methods are currently under study, while an ordinary doctor needs to prescribe a suitable therapy for a patient here and now.

Characteristics of COVID-19 infection during pregnancy and childbirth

2021 ◽  
Vol 65 (04) ◽  
pp. 24-27
Author(s):  
Fatma Rasim qızı Hacıyeva ◽  
Keyword(s):  
Pregnant Women ◽  
Key Words ◽  
Diagnosis And Treatment ◽  
Chinese City ◽  
Pregnancy And Childbirth ◽  
Coronavirus Infection

A new coronavirus infection that broke out in the Chinese city of Wuhan in 2019 went down in history as an international emergency. The article provides an overview of the Etios-pathogenesis, clinic, diagnosis and treatment of COVID-19 in pregnant women and during menopause based on available literature sources. I hope that this information will be a valuable and informative source for practitioners, as well as students and residents. Key words: COVID-19, coronvirus, pregnancy, postpartum

Obstetric and perinatal outcomes in women with threatened interruption of pregnancy, living in the armed conflict zone

2020 ◽  
pp. 21-24
Author(s):  
I.Yu. Romanenko ◽  
Keyword(s):  
Pregnant Women ◽  
Inflammatory Diseases ◽  
Perinatal Outcomes ◽  
Control Group ◽  
Operative Delivery ◽  
Pregnancy And Childbirth ◽  
Group I ◽  
History Of ◽  
Complicated Course ◽  
Female Genital

The objective: was to evaluate the course of pregnancy, childbirth and perinatal outcomes of delivery of women with threatened interruption of pregnancy (TIP), living in the Lugansk region, to improve treatment and preventive measures and prevent obstetric and perinatal complications in such women. Materials and methods. A prospective clinical and statistical analysis of the course of pregnancy and childbirth of 86 pregnant women in first and second trimesters of pregnancy were hospitalized regarding TIP in the hospitals located in the Luhansk region was performed (group I). The control group consisted of 64 pregnant women with non-complicated obstetric anamnesis and physiological course of pregnancy with similar gestational period of pregnancy and place of residence (group II). Results. In women of group I, a history of female genital inflammatory diseases was significantly more frequent, and a complicated course of pregnancy and childbirth was registered. The number of cases of acute respiratory viral infection (ARVI) was in 4, isthmic-cervical insufficiency (ICI) was in 3 times more often than in healthy pregnant women, asymptomatic bacteriuria, recurring TIP, gestational pyelonephritis and ureaplasma infection were found only in pregnant women of group I, the number of cases of anemia there was no significant difference. 13 (15.12%) of women of group I and 3 (4.69%) of group II (p=0.041) had spontaneous preterm birth at 33–37 weeks of gestation; operative delivery was registered in 23 (26.74%) and 8 (12.50%) cases, respectively (p=0.033). It was established that recurrent TIP, ARVI during this pregnancy, ICI, gestational pyelonephritis are statistically significant risk factors for preterm delivery and operative delivery. Premature rupture of the membranes was found in 1.58, weakness of labor – in 2.2, premature detachment of a normally located placenta – in 6, fetal distress – in 1.9 times more often in women of group I, central placenta previa was noted only in group I. Conclusions. The complicated course of the first and second trimesters of pregnancy, in particular, recurrent TIP, ARVI during this pregnancy, ICI, gestational pyelonephritis, had a direct effect on frequency increase of premature termination of pregnancy and operative delivery in patients of the main group compared with women of the control group. The presence of a history of chronic female genital inflammatory diseases, sexually transmitted infections, ARVI during this pregnancy, TIP in the first and second trimesters, allows pregnant women to be at high risk of developing gestational complications in order to conduct timely treatment. Key words: pregnancy, the threat of abortion, childbirth, the condition of newborns.

scholarly journals SYMPHYSIOPATHIA AS AN INTERDISCIPLINARY PROBLEM

2020 ◽  
Vol 75 (3) ◽  
pp. 20-25
Author(s):  
A.A. Vorobyev ◽  
◽  
M.S. Selikhova ◽  
O.V. Il’ina ◽  
M.S. Yаkovenko ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Connective Tissue ◽  
Pregnant Women ◽  
Musculoskeletal System ◽  
Diagnosis And Treatment ◽  
Cause And Effect ◽  
Pregnancy And Childbirth ◽  
Connective Tissue Dysplasia ◽  
Criteria For Diagnosis

Symphysiopathia is one of the complications of the musculoskeletal system that occurs in the second half of pregnancy and childbirth, which can limit the functionality of patients and worsen the quality of life. Symphysiopathia often becomes an interdisciplinary problem that requires participation in the diagnosis and treatment of not only obstetricians and gynecologists, but also traumatologists, urologists and other specialists. Information about the frequency of occurrences of symphysiopathia is contradictory and registered in the range from 0,03 to 2,8 %. These contradictions are caused by the lack of clear criteria for diagnosis, overall terminology and low clinical alertness of treating doctors. The terminology «symphysitis» is not relevant, because it indicates the inflammatory genesis of the disease. Currently, the most appropriate term is «symphysiopathia», which reflects the leading (but not the only) symptom of the disease-pain. Modern research shows that the development of symphysiopathia in pregnant women is based on a combination of several fundamental factors – biomechanical causes, undifferentiated connective tissue dysplasia and magnesium and calcium deficiency.There is no consensus about cause-and-effect interrelation, and this problem needs to be studied.

FEATURES OF THE COURSE OF PREGNANCY / CHILDBIRTH / POSTPARTUM PERIOD IN WOMEN WITH POSITIVE RESULTS FOR COVID-19

2021 ◽  
pp. 10-14
Author(s):  
S.Sh. Isenova ◽  
G. Zh. Bodykov ◽  
A.S. Shukirbaeva ◽  
M.O. Kubesova ◽  
M.U. Davranova ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Pregnant Women ◽  
Postpartum Period ◽  
Clinical Symptoms ◽  
Diagnostic Methods ◽  
Doppler Studies ◽  
X Ray ◽  
Archival Material ◽  
Pregnancy And Childbirth ◽  
Positive Results

A retrospective analysis was carried out according to the archival material of the center of perinatology and pediatric cardiac surgery in Almaty for 2020. The analysis was carried out in pregnant women with COVID-19, a total of 150 stories were examined. The features of the course of pregnancy and childbirth were assessed by studying the data of laboratory diagnostic methods of research, clinical symptoms, X-ray, ultrasound, Doppler studies. The study highlights the features of pregnancy, childbirth and the postpartum period in women infected with COVID-19.

scholarly journals Risk Factors, Clinical Symptoms, Laboratory Findings and Imaging of Pregnant Women Infected with COVID-19 in North of Iran

2020 ◽  
Vol 23 (12) ◽  
pp. 856-863
Author(s):  
Soudabeh Kazemi Aski ◽  
Seyedeh Hajar Sharami ◽  
Fatemeh Hosseinzadeh ◽  
Ezat Hesni ◽  
Seyedeh Fatemeh Dalil Heirati ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Viral Infections ◽  
Clinical Symptoms ◽  
Laboratory Finding ◽  
The Body ◽  
Shortness Of Breath ◽  
Laboratory Findings ◽  
Pregnancy And Childbirth ◽  
Severe Stage

Background: Due to the physiological changes in the body during pregnancy, the increased susceptibility to viral infections during this period and also the high prevalence of coronavirus disease 2019 (COVID-19) in the Guilan province, Iran, this study aimed to evaluate risk factors, clinical symptoms, laboratory findings and imaging of pregnant mothers with COVID-19. Methods: In this descriptive study, 70 pregnant women aged 17–41 years with COVID-19 who were hospitalized from early March to late April 2020 were enrolled. Sampling was performed by census and from all hospitals in Guilan. The research instruments included a researcher-made questionnaire, including demographic characteristics, clinical symptoms, medical examinations, and paraclinical results. Data were analyzed with SPSS version 16. Frequency and percent were used to describe qualitative variables; for quantitative variables, if they were normally distributed, mean and standard deviation were used, and if they were non-normal, median and interquartile range (IQR) were used. Results: The most severe symptoms recorded in mothers at the time of hospitalization were fever (47%), shortness of breath (16%) and cough (15%), respectively. One of 68 (1%) was in the severe stage of the disease and two mothers (2%) were in critical condition and admitted to the intensive care unit and finally died. Fifty-five of 66 women (83%) had lymphopenia, 22 of 42 (52%) tested positive on PCR, and 30 of 33 (90%) had an increase in lactate dehydrogenase (LDH) levels.Results showed that 15 of 32 patients who gave birth had preterm delivery (46%). Conclusion: The most common manifestations of the disease in pregnant women were fever, cough and shortness of breath, and in some cases muscle pain. The most common laboratory finding in infected mothers was lymphopenia. Complications of pregnancy and childbirth in women included an increase in cesarean delivery.

Epidemiological Characterization of the Infection by Treponema Pallidum in Pregnant Women in Beira City, Sofala, Mozambique

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Nchowela Guido
Keyword(s):  
Pregnant Women ◽  
Congenital Syphilis ◽  
Health Centre ◽  
Treponema Pallidum ◽  
Timely Manner ◽  
Pregnancy And Childbirth ◽  
Epidemiological Characterization ◽  
Active Syphilis ◽  
Structured Questionnaire

Introduction: Syphilis is one of several diseases that can be transmitted during pregnancy and childbirth, which can lead to complications during pregnancy and in the newborn. This is especially so when the pregnant woman is not diagnosed or treated properly and in a timely manner. Methodology: Data from 262 pregnant women prospectively included, aged 18-41years, attended at the Ponta Gêa Health Centre for antenatal clinics has been analyzed from January to September of 2016. In the prospective study, a rapid treponemal and a non-treponemal test were performed. A structured questionnaire was used to collect socio demographic and clinical variables, which was developed from the literature review. Results: The prevalence of active syphilis was 11.8%; the majority of reactive pregnant women were aged 18-25years (55.4%), (61.3%) of pregnant women were treated with doses below those recommended; only a small number of the partners were treated successfully. The highest seroprevalence of syphilis was found in housewives (77%), in those who attended primary education (71.6%) in those who had a monthly income of 1000- 3000 MZN (70.3%), in those with two or more pregnancies (55.7%) and living with someone has husband and wife (63.5%). The syphilis/HIV co-infection rate was high. Conclusion: According to the results obtained in this study, urgent measures are needed to assess the problems encountered and to improve the screening approach, treatment and monitoring of syphilis during pregnancy in order to prevent the cases of congenital syphilis.

Clinical and immunological aspects of pregnancy and childbirth in pregnant women with influenza А (H1N1)

2020 ◽  
Vol 18 (2) ◽  
pp. 51-54
Author(s):  
E. P. SHATUNOVA ◽  
◽  
O. I. LINEVA ◽  
D. M. KALIMATOVA ◽  
◽  
...  
Keyword(s):  
Pregnant Women ◽  
Pregnancy And Childbirth

HUBUNGAN UMUR DAN PARITAS IBU DENGAN KEJADIAN HIPEREMESIS GRAVIDARUM DI RUMAH SAKIT UMUM PUSAT Dr. MOHAMMAD HOESIN PALEMBANG TAHUN 2011

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Wahyu Ida Muliana Wahyu Ida Muliana
Keyword(s):  
Pregnant Women ◽  
Medical Record ◽  
Random Sampling ◽  
Hyperemesis Gravidarum ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Systematic Random Sampling ◽  
Pregnancy And Childbirth ◽  
Chi Square Test

ABSTRACT Hyperemesis Gravidarum marked excessive nausea and vomiting in pregnant women at a young age. WHO estimates that 536,000 women died from direct complications of pregnancy and childbirth. One complication of pregnancy is Hyperemesis Gravidarum. Hyperemesis Gravidarum in the world has been estimated to occur in 1-2% of pregnant. According to data from the Medical Record of Dr. Mohammad Hoesin Palembang Hospital, the incidence of Hyperemesis Gravidarum in 2011 there were 72 people of 661 pregnant women. The purpose of this reseach was to determine the relationship between maternal age and parity with Hyperemesis Gravidarum in Dr. Mohammad Hoesin Palembang Hospital 2011. The Design of this reseach used Cross Sectional by analytic approach survey. The population of this reseach are all of mother who gestational ≤ 16 weeks (four months) in the Installation of Obstetrics and Gynecology, Dr. Mohammad Hoesin Palembang Hospital in January to December of 2011 with the sample of 661 people which taken by systematic random sampling and the reseach was conducted from 17 April to 24 April 2012.  Each variable that was observed in tests using Chi-Square test with a (0.05).  The results of this study showed that 5.9% of mothers with hyperemesis gravidarum, 21.8% of mothers with high risk age, and 30.0% primigravida. Chi-Square test showed no significant relationship between age (p value = 0.000) and parity (p value = 0.000) with the incidence of hyperemesis gravidarum. Expected to the Hospital to be implemented properly instructed how to provide counseling to pregnant women about pregnancy and childbirth, as well as provide confidence that the nausea and vomiting is a symptom of physiology in pregnancy.   ABSTRAK Hiperemesis Gravidarum ditandai mual dan muntah yang berlebihan terjadi pada ibu hamil di usia muda. WHO memperkirakan 536.000 perempuan meninggal dunia akibat langsung dari komplikasi kehamilan dan persalinan. Salah satu komplikasi kehamilan adalah Hiperemesis Gravidarum. Insiden Hiperemesis Gravidarum di dunia telah diperkirakan terjadi pada 1-2% wanita hamil. Menurut data dari Medical Record Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang, angka kejadian Hiperemesis Gravidarum pada tahun 2011 terdapat 72 orang dari 661 ibu hamil. Tujuan penelitian ini adalah untuk mengetahui hubungan antara umur dan paritas ibu dengan kejadian Hiperemesis Gravidarum pada ibu di Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang tahun 2011. Desain Penelitian ini menggunakan survei analitik dengan pendekatan Cross Sectional. Populasi penelitian ini adalah dengan umur kehamilan ≤ 16 minggu (4 bulan) yang pernah dirawat inap di Instalasi Kebidanan dan Penyakit Kandungan Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang pada bulan Januari-Desember tahun 2011 dengan jumlah sample 661 orang yang diambil secara systematic Random Sampling (secara acak sistematis) dan penelitian ini dilakukan dari tanggal 17 April sampai dengan 24 April 2012. Masing-masing variabel yang diteliti di uji dengan menggunakan uji Chi-Square dengan a (0,05). Hasil penelitian ini menunjukkan bahwa 5,9% ibu mengalami hiperemesis gravidarum, 21,8% ibu dengan umur resiko tinggi, dan 30,0% ibu primigravida. Uji Chi-Square menunjukkan ada hubungan yang bermakna antara umur (p value = 0,000) dan paritas (p value = 0,000) dengan kejadian hiperemesis gravidarum. Diharapkan dapat menjadi masukan bagi pihak Rumah Sakit agar dilaksanakan penyuluhan dengan cara memberikan konseling terhadap ibu hamil tentang kehamilan dan persalinan, serta memberikan keyakinan bahwa mual muntah merupakan gejala fisiologi pada kehamilan.

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