The role of lifestyle habits in the prevalence of overweight and obesity among students

At the end of 2019, a new coronavirus (COVID-19) appeared on the world scene, which mainly affects the respiratory system, causing pneumonia and multi-organ failure, and, although it starts with common symptoms such as shortness of breath and fever, in about 2–3% of cases it leads to death. Unfortunately, to date, no specific treatments have been found for the cure of this virus and, therefore, it is advisable to implement all possible strategies in order to prevent infection. In this context, it is important to better define the role of all behaviors, in particular nutrition, in order to establish whether these can both prevent infection and improve the outcome of the disease in patients with COVID-19. In the literature, it is widely shown that states of malnutrition, overweight, and obesity negatively affect the immune system, leading to viral infections, and several studies have shown that nutritional interventions can act as immunostimulators, helping to prevent viral infections. Even if several measures, such as the assumption of a specific diet regimen, the use of dietary supplements, and other similar interventions, are promising for the prevention, management, and recovery of COVID-19 patients, it is important to highlight that strong data from randomized clinical trials are needed to support any such assumption. Considering this particular scenario, we present a literature review addressing several important aspects related to diet and SARS-CoV-2 infection, in order to highlight the importance of diet and supplementation in prevention and management of, as well as recovery from COVID-19.

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The Potential Role of Exosomes in Child and Adolescent Obesity

Children ◽

10.3390/children8030196 ◽

2021 ◽

Vol 8 (3) ◽

pp. 196

Author(s):

Ioanna Maligianni ◽

Christos Yapijakis ◽

Flora Bacopoulou ◽

George Chrousos

Keyword(s):

Child And Adolescent ◽

Cardiovascular Complications ◽

Adolescent Obesity ◽

Overweight And Obesity ◽

Calorie Intake ◽

Target Cells ◽

Special Role ◽

Exosomal Mirnas ◽

Risk Biomarkers

Child and adolescent obesity constitute one of the greatest contemporary public health menaces. The enduring disproportion between calorie intake and energy consumption, determined by a complex interaction of genetic, epigenetic, and environmental factors, finally leads to the development of overweight and obesity. Child and adolescent overweight/obesity promotes smoldering systemic inflammation (“para-inflammation”) and increases the likelihood of later metabolic and cardiovascular complications, including metabolic syndrome and its components, which progressively deteriorate during adulthood. Exosomes are endosome-derived extracellular vesicles that are secreted by a variety of cells, are naturally taken-up by target cells, and may be involved in many physiological and pathological processes. Over the last decade, intensive research has been conducted regarding the special role of exosomes and the non-coding (nc) RNAs they contain (primarily micro (mi) RNAs, long (l) non-coding RNAs, messenger (m) RNAs and other molecules) in inter-cellular communications. Through their action as communication mediators, exosomes may contribute to the pathogenesis of obesity and associated disorders. There is increasing evidence that exosomal miRNAs and lncRNAs are involved in pivotal processes of adipocyte biology and that, possibly, play important roles in gene regulation linked to human obesity. This review aims to improve our understanding of the roles of exosomes and their cargo in the development of obesity and related metabolic and inflammatory disorders. We examined their potential roles in adipose tissue physiology and reviewed the scarce data regarding the altered patterns of circulating miRNAs and lncRNAs observed in obese children and adolescents, compared them to the equivalent, more abundant existing findings of adult studies, and speculated on their proposed mechanisms of action. Exosomal miRNAs and lncRNAs could be applied as cardiometabolic risk biomarkers, useful in the early diagnosis and prevention of obesity. Furthermore, the targeting of crucial circulating exosomal cargo to tissues involved in the pathogenesis and maintenance of obesity could provide a novel therapeutic approach to this devastating and management-resistant pandemic.

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Nurse Documentation of Child Weight-Related Health Promotion at Age Four in Sweden

Nursing Reports ◽

10.3390/nursrep11010008 ◽

2021 ◽

Vol 11 (1) ◽

pp. 75-83

Author(s):

Anna Svensson Sehic ◽

Mikaela Persson ◽

Eva K. Clausson ◽

Eva-Lena Einberg

Keyword(s):

Health Care ◽

Child Health ◽

Rank Order ◽

Overweight And Obesity ◽

Child Health Service ◽

Child Health Care ◽

Lifestyle Habits ◽

Chi Square ◽

Analyse Data ◽

Record Review

(1) Background: Overweight and obesity in children have increased worldwide and tend to persist into adolescence and adulthood. The Child Health Service (CHS) has an important role in providing health-promotive interventions, and such interventions are required to be documented in a child’s health record. The aim of the study was to investigate Child Health Care (CHC) nurses’ documentation of weight-related, health-promotive interventions in the Child Health Care Record (CHCR) regarding lifestyle habits in connection to the four-year visit. (2) Methods: A record review of 485 CHCRs using a review template was accomplished. Of the included CHS units, four used electronic records and two used paper records. Chi-square tests and Spearman’s rank-order correlations were used to analyse data. (3) Results: The results showed that CHC nurses document interventions regarding lifestyle habits to a low extent, although children with overweight/obesity seemed to undergo more interventions. There was also a difference between electronic and paper records. (4) Conclusions: The consequences of not documenting the interventions in the CHCR make it difficult to follow up and demonstrate the quality of the CHC nurse’s work. There is a need for more research to gain a deeper understanding of the reasons that the work of CHC nurses is not visible in children’s health records.

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Obesity and inflammatory bowel disease

Gastroenterologie a hepatologie ◽

10.48095/ccgh202120 ◽

2021 ◽

Vol 75 (1) ◽

pp. 20-28

Author(s):

Vladimír Teplan ◽

Milan Lukáš

Keyword(s):

Inflammatory Bowel Disease ◽

Adipose Tissue ◽

Bowel Disease ◽

Intestinal Inflammation ◽

Perioperative Complications ◽

Overweight And Obesity ◽

Special Role ◽

Low Concentrations ◽

Inflammatory Bowel

The incidence and prevalence of overweight and obesity has dramatically increased in the last decades and is generally considered to be global pandemics. The incidence of inflammatory bowel disease (IBD) is rising parallel with overweight and obesity. Contrary to a conventional believe, about 15–40% patients with IBD are obese, which can contribute to the development and course of IBD, especially in Crohn’s disease. Although the findings of some cohort studies are still conflicting, recent results indicate a special role of visceral adipose tissue and particularly mesenteric adipose tissue known as creeping fat, leading to intestinal inflammation. The involvement of altered adipocyte function and deregulated production of adipokines such as leptin and adiponectin has been suggested in the pathogenesis of IBD. The emerging role of Western diet and microbiota can also open new possibilities in IBD management. The effect of obesity on the IBD-related therapy remains to be studied. The finding that obesity results in suboptimal response to the therapy, potentially promoting rapid clearance of biologic agents and thus leading to their low concentrations, has a great importance. Obesity also makes IBD colorectal surgery technically challenging and might increase a risk of perioperative complications.

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Role of swasthavritta in preventing lifestyle disorders with reference to obesity.

National Journal of Research in Ayurved Science ◽

10.52482/ayurlog.v8i01.497 ◽

2020 ◽

Vol 8 (01) ◽

Author(s):

Saiprasad Rathod

Keyword(s):

Life Style ◽

Overweight And Obesity ◽

Curative Effect ◽

Unhealthy Eating ◽

The World ◽

Diet Pattern ◽

Reduce Risk ◽

Day By Day

life style disorders are defined as the disorders linked with the way of people live their life. this is commonly caused by alcohol, drugs and smoking as well as lack of physical activity and unhealthy eating. Diseases that mostly have an effect on our lifestyle are the heart disease, stroke, obesity and type 2 diabetes mellitus. overweight and obesity are the fifth leading risk of global death, worldwide obesity has more than doubled since 1980. In 2014, more than 1.9 million adult, 18 yrs. and older, were overweight, of these over 600 million men and women were obese. Due to faulty lifestyle and diet pattern the incidence of obesity is increasing day by day all over the world. according to Ayurveda obesity also known as sthoulya or medoroga. according to Ayurveda obesity can lead to many life style disorders. Ayurveda has a great importance to reduce risk of lifestyle disorders. There are so many concepts which will reduce the risk of life style disorders. Acc. To swasthavritta there are so many pathya aahar kalpna, various type of aasanas and yoga described thus, above factors has wonderful preventive and curative effect on obesity.

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Role of Overweight and Obesity in Occurrence and Outcomes of Venous Thromboembolism

Journal of the American College of Surgeons ◽

10.1016/j.jamcollsurg.2016.08.167 ◽

2016 ◽

Vol 223 (4) ◽

pp. e63-e64

Author(s):

Ayman El-Menyar ◽

Hassan Al-Thani ◽

Mohammad Asim

Keyword(s):

Venous Thromboembolism ◽

Overweight And Obesity

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The Role of Arachidonic and Linoleic Acid Derivatives in Pathological Pregnancies and the Human Reproduction Process

International Journal of Molecular Sciences ◽

10.3390/ijms21249628 ◽

2020 ◽

Vol 21 (24) ◽

pp. 9628

Author(s):

Małgorzata Szczuko ◽

Justyna Kikut ◽

Natalia Komorniak ◽

Jacek Bilicki ◽

Zbigniew Celewicz ◽

...

Keyword(s):

Diabetes Mellitus ◽

Fatty Acids ◽

Linoleic Acid ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Overweight And Obesity ◽

Male Reproduction ◽

Human Reproduction ◽

In Pregnancy

The aim of the available literature review was to focus on the role of the proinflammatory mediators of AA and LA derivatives in pathological conditions related to reproduction and pregnancy. Arachidonic (AA) and linoleic acid (LA) derivatives play important roles in human fertility and the course of pathological pregnancies. Recent studies have demonstrated that uncontrolled inflammation has a significant impact on reproduction, spermatogenesis, endometriosis, polycystic ovary syndrome (PCOS) genesis, implantation, pregnancy and labor. In addition, cyclooxygenase-mediated prostaglandins and AA metabolite levels are higher in women’s ovarian tissue when suffering from PCOS. It has been demonstrated that abnormal cyclooxygenase-2 (COX-2) levels are associated with ovulation failure, infertility, and implantation disorders and the increase in 9-HODE/13-HODE was a feature recognized in PCOS patients. Maintaining inflammation without neutrophil participation allows pregnant women to tolerate the fetus, while excessive inflammatory activation may lead to miscarriages and other pathological complications in pregnancies. Additionally AA and LA derivatives play an important role in pregnancy pathologies, e.g., gestational diabetes mellitus, preeclampsia (PE), and fetal growth, among others. The pathogenesis of PE and other pathological states in pregnancy involving eicosanoids have not been fully identified. A significant expression of 15-LOX-1,2 was found in women with PE, leading to an increase in the synthesis of AA and LA derivatives, such as hydroxyeicozatetraenoic acids (HETE) and hydroxyoctadecadiene acids (HODE). Synthesis of the metabolites 5-, 8-, 12-, and 15-HETE increased in the placenta, while 20-HETE increased only in umbilical cord blood in women with preeclampsia compared to normal pregnancies. In obese women with gestational diabetes mellitus (GDM) an increase in epoxygenase products in the cytochrome P450 (CYP) and the level of 20-HETE associated with the occurrence of insulin resistance (IR) were found. In addition, 12- and 20-HETE levels were associated with arterial vasoconstriction and epoxyeicosatrienoic acids (EETs) with arterial vasodilatation and uterine relaxation. Furthermore, higher levels of 5- and 15-HETE were associated with premature labor. By analyzing the influence of free fatty acids (FFA) and their derivatives on male reproduction, it was found that an increase in the AA in semen reduces its amount and the ratio of omega-6 to omega-3 fatty acids showed higher values in infertile men compared to the fertile control group. There are several studies on the role of HETE/HODE in relation to male fertility. 15-Hydroperoxyeicosatetraenoic acid may affect the integrity of the membrane and sperm function. Moreover, the incubation of sperm with physiologically low levels of prostaglandins (PGE2/PGF2α) improves the functionality of human sperm. Undoubtedly, these problems are still insufficiently understood and require further research. However, HETE and HODE could serve as predictive and diagnostic biomarkers for pregnancy pathologies (especially in women with risk factors for overweight and obesity). Such knowledge may be helpful in finding new treatment strategies for infertility and the course of high-risk pregnancies.

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