Comparison of the Efficacy of Intravenous, Subcutaneous, and Suppository Morphine in Reducing Post Hysterectomy Pain

Background and aims: Postoperative pain has always been considered by surgeons because of its various complications. The aim of this study was to compare the effect of intravenous, subcutaneous and suppository morphine in reducing post-hysterectomy pain. Materials and Methods: In this clinical trial, 90 patients undergoing hysterectomy were randomized into three groups of 30 each using simple randomization, namely, intravenous, subcutaneous, and suppository morphine (10 mg). Before intervention and 4, 8, 12, and 16 hours after intervention, pain intensity was measured using visual analogue scale (VAS). Relative frequency of nausea, vomiting, itching, bradypnea, and apnea in all groups was recorded. Data were analyzed by SPSS version16.0. Results: Mean pain severity at 0 hour postoperatively (P=0.004), 4 hours postoperatively (P=0.009), 8 hours postoperatively (P=0.009), and 12 hours postoperatively (P=0.001) was significantly higher in the suppository morphine group than in the other two groups. There was no significant difference in pain severity at 16 hours postoperatively among the three groups (P=0.446). According to the results of repeated measures ANOVA, changes in pain severity at the five intervals were statistically significant in all three groups (subcutaneous, intravenous, and suppository morphine groups) (P<0.001). There was also a statistically significant difference in pain severity at the studied intervals among the three groups (P<0.001). The frequency of nausea (P=0.05) and vomiting (P=0.84) was higher in the suppository group than in the other two groups, although the difference was not statistically significant (P=0.05). Conclusion: The results of this study indicated better efficacy of subcutaneous and intravenous morphine in reducing post-hysterectomy pain compared with suppository morphine.

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Sight-Singing Scores of High School Choristers with Extensive Training in Movable Solfège Syllables and Curwen Hand Signs

Journal of Research in Music Education ◽

10.1177/0022429408323290 ◽

2008 ◽

Vol 56 (3) ◽

pp. 255-266 ◽

Cited By ~ 4

Author(s):

Alan C. McClung

Keyword(s):

High School ◽

Knowledge Base ◽

Repeated Measures ◽

The Other ◽

Sight Singing ◽

Repeated Measures Anova ◽

Pedagogical Strategy ◽

Extensive Training ◽

Significant Difference ◽

The Mean

Randomly chosen high school choristers with extensive training in solfège syllables and Curwen hand signs ( N = 38) are asked to sight-sing two melodies, one while using Curwen hand signs and the other without. Out of a perfect score of 16, the mean score with hand signs was 10.37 ( SD = 4.23), and without hand signs, 10.84 ( SD = 3.96). A repeated-measures ANOVA revealed no statistically significant difference, F(1, 37) = .573, p = .454. These findings support the results of five earlier studies; however, because earlier studies were limited to students who were minimally trained in movable solfège syllables and Curwen hand signs, this study expands the knowledge base. Relationships between performance scores and instrumental experience, class grade, sight-singing experience, and hand sign experience were also examined. A pedagogical strategy for linking Curwen hand signs with students' preferred modes of learning (especially the kinesthetic mode) is recommended.

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13 EFFECT OF 6 TIMES REUSING OF CONTROLLED INTERNAL DRUG RELEASE (CIDR) FOR SHORT TERM (6 DAYS) ON PROGESTERONE LEVEL AND REPRODUCTIVE PERFORMANCE OF AWASSI EWES

Reproduction Fertility and Development ◽

10.1071/rdv28n2ab13 ◽

2016 ◽

Vol 28 (2) ◽

pp. 136 ◽

Cited By ~ 1

Author(s):

A. Swelum ◽

A. Mouamen ◽

A. Alowaimer

Keyword(s):

Pregnancy Rate ◽

Reproductive Performance ◽

Repeated Measures ◽

The Other ◽

Serum Concentrations ◽

Short Term ◽

Chi Square ◽

Withdrawal Time ◽

Repeated Measures Anova ◽

Significant Difference

This study was carried out using 120 multiparous Awassi ewes during breeding season to compare the effect of 6 times reusing of CIDR short term (6 days) on hormonal and reproductive performance. Ewes were equally and randomly allotted into 6 consecutive oestrus synchronization treatments. For group CIDR6×1, the ewes (n = 20) received new CIDR for 6 days with 300 IU of eCG at withdrawal time. For the other 5 groups, the same protocol was used, differing only by the use of the same CIDR for a second time in CIDR6×2, for a third time in CIDR6×3, for a fourth time in CIDR6×4, for a fifth time in CIDR6×5, and for a sixth time in CIDR6×6. Oestrus was detected using a vasectomized ram starting 12 h after progestagen withdrawal and repeated every 12 h up to 84 h. Blood samples were collected at withdrawal time (Day 6). Progesterone serum concentrations were measured using commercial ELISA kits and micro-titrimetric plates. Timed insemination was performed 48 h after CIDR withdrawal. Pregnancy and number of fetuses were diagnosed by ultrasonography at Day 23 after insemination and confirmed at Day 35 and 60. Comparisons among groups was evaluated using chi-square (χ2) test in all parameters except hormones levels, which was analysed by repeated-measures ANOVA, using SAS (SAS Institute Inc., Cary, NC, USA, 2000). The results revealed that there is no significant difference between the percentages of ewes detected in heat in groups CIDR6×1, CIDR6×2, and CIDR6×3 (55, 70, and 55%, respectively). While, the percentages of ewes detected in heat in group CIDR6×2 was significantly (P ≤ 0.05) higher than in groups CIDR6×4, CIDR6×5, and CIDR6×6 (35, 35, 31.58%, respectively). On the other hand, pregnancy rate was significantly (P ≤ 0.05) higher in CIDR6×2 (65%; 13/20) than CIDR6×3, CIDR6×4, CIDR6×5, and CIDR6×6 (30, 30, 30, and 15.79, respectively). No significant difference was detected in pregnancy rate between CIDR6×1 and CIDR6×2. No significant differences were detected in progesterone between CIDR6×1 and CIDR6×2, CIDR6×3, CIDR6×4, CIDR6×5, and CIDR6×6 (1.73, 1.67, 1.87, 1.57, 1.60, and 1.36 ng mL–1, respectively). These results indicated that reusing of CIDR devices for short term are efficient in synchronizing oestrus in ewes.

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Attention Deficit Hyperactivity Disorder, Creativity, and the Effects of Methylphenidate

PEDIATRICS ◽

10.1542/peds.91.4.816 ◽

1993 ◽

Vol 91 (4) ◽

pp. 816-819

Author(s):

Jeanne B. Funk ◽

John B. Chessare ◽

Michael T. Weaver ◽

Anita R. Exley

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Attention Deficit ◽

Repeated Measures ◽

Creative Thinking ◽

Adhd Group ◽

Hyperactivity Disorder ◽

Significant Difference ◽

Quasi Experimental ◽

The Difference ◽

Clinically Significant

Given that children with attention deficit hyperactivity disorder (ADHD) are more impulsive than peers, this study explored whether they are correspondingly more creative, and whether creativity declines when impulsivity is decreased through methylphenidate (Ritalin) therapy. A repeated-measures quasi-experimental design was used to compare the performance of 19 boys with previously diagnosed ADHD and 21 comparison boys aged 8 through 11 on two administrations of alternate forms of the Torrance Tests of Creative Thinking-Figural (nonverbal). Boys with ADHD received prescribed methylphenidate only for the first session. Overall, mean Torrance summary scores for comparison boys (mean = 115.1, SD = 16.1) were higher than for boys with ADHD (mean = 107.6, SD = 12.7). However, the difference between means was small (7%) and did not meet the 25% criterion for a clinically significant difference. No changes in performance over time (comparison group) or medication state (ADHD group) were observed. These data suggest that, when measured nonverbally, the creative thinking performance of boys with ADHD is not superior to that of peers who do not have ADHD. Regarding the effects of methylphenidate, prescribed therapy did not influence performance on this measure of creative thinking.

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Effect of Educational Games on Self-concept Levels of Inclusive Students Studying in Secondary Schools

Journal of Education and Training Studies ◽

10.11114/jets.v6i10.3365 ◽

2018 ◽

Vol 6 (10) ◽

pp. 183

Author(s):

Serhat Üstündağ ◽

Gülsen Özcan

Keyword(s):

Secondary Schools ◽

Peer Relationships ◽

Repeated Measures ◽

Educational Games ◽

The Other ◽

Self Concept ◽

Control Group ◽

Spring Semester ◽

Significant Difference ◽

Experimental Group

This research examines the effect of educational games on self-concept levels of inclusive students enrolled in secondary schools. The research was conducted in two secondary schools in Golbasi district of Ankara, the capital of Turkey, in the spring semester of 2015 - 2016 academic year. The research employed semi-experimental design with pretest and posttest control group. Of a total of 24 students, 12 (4 girls, 8 boys) were included in the experimental group and the other 12 (6 girls, 6 boys) were included in the control group. Educational games program, an independent variable of the research, was applied for 11 weeks, 2 lessons per week. The program that did not include educational games was applied to the control group. Self-concept Scale (SCS) was used to collect data in the research. Independent group t test was used for data analysis, and for single-factor repeated measures, two-factor ANOVA test was used. The significance level was determined to be 0.05. At the end of this research, a significant difference was found in favor of the students in the experimental group in terms of physical competence, physical appearance, peer relationships and general self-concept dimensions of the self-concept scale. On the other hand, there was not any significant difference in favor of both groups in terms of the dimension of relations with parents of the scale.

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PERBANDINGAN KUALITAS PRODUK DAN MINAT MENABUNG PADA LPD DESA ADAT TAJUN DENGAN DESA ADAT TEGAL

Agrisocionomics Jurnal Sosial Ekonomi Pertanian ◽

10.14710/agrisocionomics.v4i1.5373 ◽

2020 ◽

Vol 4 (1) ◽

pp. 59-67

Author(s):

Eka Swarnadi Luh ◽

Ketut Budi Susrusa ◽

Ida Ayu Listia Dewi

Keyword(s):

Product Quality ◽

Financial Institutions ◽

Rapid Development ◽

Research Data ◽

The Other ◽

Physical Evidence ◽

Significant Difference ◽

The Difference ◽

Better Than

LPDs are non-bank financial institutions that are regulated and approved by the Regional Regulations of the Province of Bali. The management of LPD is fully handed over to the relevant Pakraman village. In line with the rapid development of LPDs, it turns out that on the other hand it shows diverse performance, so that LPDs need to pay attention to the level of product quality and customer interest in the products offered. The purpose of the study was to determine the comparison of product quality and interest in saving at the Tajun Traditional Village LPD with the Traditional Village of Tegal. The number of samples from Tajun Adat Village LPD was 98 people and the LPD of Tegal Traditional Village was 84 people. The research data were analyzed by the Mann-Whitney Test. The results showed that there was a significant difference between the quality of the products of the Adat Village of Tajun LPD and the Traditional Village of Tegal. This difference is indicated by indicators of physical evidence, reliability, responsiveness and empathy. The product quality of Tajun Adat Village's LPD is better than the traditional village of Tegal. There is a significant difference between the interest in saving the traditional village of Tajun LPD and the traditional village of Tegal. The difference is in the indicator of confidence. Interest in Saving Tajun Indigenous Village LPD is higher than the Traditional Village of Tegal.

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Beta alanine supplementation effects on metabolic contribution and swimming performance

Journal of the International Society of Sports Nutrition ◽

10.1186/s12970-020-00365-6 ◽

2020 ◽

Vol 17 (1) ◽

Cited By ~ 1

Author(s):

Matheus Silva Norberto ◽

Ricardo Augusto Barbieri ◽

Danilo Rodrigues Bertucci ◽

Ronaldo Bucken Gobbi ◽

Eduardo Zapaterra Campos ◽

...

Keyword(s):

Repeated Measures ◽

Energy Demand ◽

Swimming Performance ◽

Controlled Study ◽

Double Blind ◽

Repeated Measures Anova ◽

Beta Alanine ◽

Before And After ◽

The Difference ◽

And Performance

Abstract Background Investigations of β-alanine supplementation shows effects on metabolic (aerobic and anaerobic) participation and performance on swimming by a possible blood acidosis buffering. Considering this background, the objective of the present study was to analyze the effects of β-alanine supplementation on metabolic contribution and performance during 400-m swim. Methods Thirteen competitive swimmers underwent a 6-week, double-blind placebo-controlled study, ingesting 4.8 g.day− 1 of β-alanine or placebo. Before and after the supplementation period, the total anaerobic contribution (TAn) and 30-s all-out tethered swimming effort (30TS) were assessed. Anaerobic alactic (AnAl) and lactic energy (AnLa) was assumed as the fast component of excess post-exercise oxygen consumption and net blood lactate accumulation during exercise (∆[La−]), respectively. Aerobic contribution (Aer) was determined by the difference between total energy demand and TAn. In addition to conventional statistical analysis (Repeated measures ANOVA; p > 0.05), a Bayesian repeated measures ANOVA was used to evidence the effect probability (BFincl). Results No differences and effects were found between groups, indicating no supplementation effects. Repeated measures ANOVA, with confirmation of effect, was indicate reduce in ∆Lactate (p: 0.001; BFincl: 25.02); absolute AnLa (p: 0.002; BFincl: 12.61), fatigue index (p > 0.001; BFincl: 63.25) and total anaerobic participation (p: 0.008; BFincl: 4.89). Conclusions Thus, the results demonstrated that all changes presented were evidenced as a result of exposure to the training period and β-alanine supplementation doesn’t affect metabolic contribution and performance during 400-m freestyle.

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A comparison of animated versus static images in an instructional multimedia presentation

AJP Advances in Physiology Education ◽

10.1152/advan.00053.2015 ◽

2016 ◽

Vol 40 (2) ◽

pp. 201-205 ◽

Cited By ~ 17

Author(s):

C. J. Daly ◽

J. M. Bulloch ◽

M. Ma ◽

D. Aidulis

Keyword(s):

Student Satisfaction ◽

Undergraduate Students ◽

Three Dimensional ◽

The Other ◽

Multimedia Presentation ◽

Still Images ◽

Significant Difference ◽

Essay Question ◽

The Difference ◽

Video Compositing

Sophisticated three-dimensional animation and video compositing software enables the creation of complex multimedia instructional movies. However, if the design of such presentations does not take account of cognitive load and multimedia theories, then their effectiveness as learning aids will be compromised. We investigated the use of animated images versus still images by creating two versions of a 4-min multimedia presentation on vascular neuroeffector transmission. One version comprised narration and animations, whereas the other animation comprised narration and still images. Fifty-four undergraduate students from level 3 pharmacology and physiology undergraduate degrees participated. Half of the students watched the full animation, and the other half watched the stills only. Students watched the presentation once and then answered a short essay question. Answers were coded and marked blind. The “animation” group scored 3.7 (SE: 0.4; out of 11), whereas the “stills” group scored 3.2 (SE: 0.5). The difference was not statistically significant. Further analysis of bonus marks, awarded for appropriate terminology use, detected a significant difference in one class (pharmacology) who scored 0.6 (SE: 0.2) versus 0.1 (SE: 0.1) for the animation versus stills group, respectively ( P = 0.04). However, when combined with the physiology group, the significance disappeared. Feedback from students was extremely positive and identified four main themes of interest. In conclusion, while increasing student satisfaction, we do not find strong evidence in favor of animated images over still images in this particular format. We also discuss the study design and offer suggestions for further investigations of this type.

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Comparing the Effects of Two Feeding Methods on Metabolic Bone Disease in Newborns with Very Low Birth Weights

Global Journal of Health Science ◽

10.5539/gjhs.v8n1p249 ◽

2015 ◽

Vol 8 (1) ◽

pp. 249 ◽

Cited By ~ 12

Author(s):

Asghar Lotfi ◽

Kobra Shiasi ◽

Razieh Amini ◽

Mohammad Jahangiri ◽

Mohammad Reza Sharif ◽

...

Keyword(s):

Metabolic Disease ◽

Serum Level ◽

Metabolic Bone Disease ◽

Serum Levels ◽

The Other ◽

Metabolic Bone ◽

Preterm Formula ◽

Significant Difference ◽

Feeding Methods ◽

The Difference

INTRODUCTION: Bone metabolic disease is an important issue in newborns with very low birth weight. The 80 percent of the transport of calcium (Ca) and phosphor (P) from mother to fetus takes place in the third trimester of pregnancy. This transport process is impaired with the preterm delivery of the newborn. On the other side, breast milk and formula are not competent resources to supply sufficient amounts of Ca and P to meet the requirements of the preterm newborn, thereby a greater reduction in the storage of these minerals. The current study has been done with the purpose of comparing the effects of two feeding methods on the indices of metabolic bone disease in newborns with very low birth weights (VLBW). MATERIALS & METHODS: The study design was cohort and the study was done on a total of 58 newborns with very low birth weights in Kashan Shahid Beheshti Hospital. The newborns were divided into two groups with 29 placed in the group of alternate feeding on preterm formula (preNan) and the other 29 placed in the group of breast milk and preterm formula (preNan). Eventually, the indices of bone metabolic disease were measured in both groups and were statistically analyzed. RESULTS: The difference between the mean serum levels of Ca in different weeks and also between the two groups were significant (p=0.001). However, the changes in mean serum level of P in the two groups were not significant (P=0.151). The comparison of serum levels of alkaline phosphatase between the two groups indicated that their difference was significant and that they had been influenced by the feeding method (P=0.001). The serum level of bicarbonate, when compared between the two groups, was found to make a significant difference (P=0.001). The difference between the two feeding methods in precipitating rickets and osteopenia was not significant. CONCLUSION: According to the findings of current study, feeding on preterm formula (preNan) is associated with better and more desirable results, though the occurrence of rickets in the two groups had no significant difference.

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Optical characteristics of cryoconite (surface dust) on glaciers: the relationship between light absorbency and the property of organic matter contained in the cryoconite

Annals of Glaciology ◽

10.3189/172756402781817743 ◽

2002 ◽

Vol 34 ◽

pp. 409-414 ◽

Cited By ~ 78

Author(s):

Nozomu Takeuchi

Keyword(s):

Organic Matter ◽

Humic Substances ◽

Visible Region ◽

The Other ◽

Optical Characteristics ◽

The Arctic ◽

Mineral Particles ◽

Significant Difference ◽

The Difference ◽

Chemical Conditions

AbstractOptical characteristics of the cryoconite collected from nine glaciers in the Himalaya, Tibet and the Arctic (Canada and Svalbard) were analyzed. The spectral light reflectance (visible region) of the cryoconite on the six glaciers in the Arctic and the Himalayawas generally low, indicating high light absorbency (dark coloration) of the cryoconite. In contrast, the spectral reflectances of the cryoconite on the three glaciers in Tibet were significantly higher than on the other glaciers. There was no significant difference in the spectral reflectance of mineral particles contained in the cryoconite between the Tibetan and the other glaciers, indicating that the difference in the albedo of the cryoconites is not due to the mineral particles, but due to organic matter contained in the cryoconite. Chemical analysis of the organic matter in the cryoconites revealed that the light absorbency of cryoconites is due to the amount of humic substances, which are dark-colored organic substances, the residue of bacterial decomposition of organic matter. The cryoconite of the three glaciers in Tibet contained significantly smaller amounts of humic substances than that of the other glaciers, probably due to different biological or chemical conditions. Results show that the formation of the humic substances in the cryoconite affects its optical characteristics, and possibly affects the surface albedo of the glaciers.

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Evaluation of the Repeatability and Accuracy of the Wideband Real-Ear-to-Coupler Difference

Journal of the American Academy of Audiology ◽

10.3766/jaaa.17007 ◽

2018 ◽

Vol 29 (06) ◽

pp. 520-532 ◽

Cited By ~ 1

Author(s):

Jonathan M. Vaisberg ◽

Paula Folkeard ◽

John Pumford ◽

Philipp Narten ◽

Susan Scollie

Keyword(s):

Hearing Aids ◽

High Frequency ◽

Repeated Measures ◽

Ear Canal ◽

Repeated Measures Anova ◽

Absolute Agreement ◽

The Difference ◽

Db Difference ◽

Additional Clinical Benefit ◽

Reported Data

AbstractThe real-ear-to-coupler difference (RECD) is an ANSI standardized method for estimating ear canal sound pressure level (SPL) thresholds and assisting in the prediction of real-ear aided responses. It measures the difference in dB between the SPL produced in the ear canal and the SPL produced in an HA-1 2-cc coupler by the same sound source. Recent evidence demonstrates that extended high-frequency bandwidth, beyond the hearing aid bandwidth typically measured, is capable of providing additional clinical benefit. The industry has, in turn, moved toward developing hearing aids and verification equipment capable of producing and measuring extended high-frequency audible output. As a result, a revised RECD procedure conducted using a smaller, 0.4-cc coupler, known as the wideband-RECD (wRECD), has been introduced to facilitate extended high-frequency coupler-based measurements up to 12.5 kHz.This study aimed to (1) compare test–retest repeatability between the RECD and wRECD and (2) measure absolute agreement between the RECD and wRECD when both are referenced to a common coupler.RECDs and wRECDs were measured bilaterally in adult ears by calculating the dB difference in SPL between the ear canal and coupler responses. Real-ear probe microphone measures were completed twice per ear per participant for both foam-tip and customized earmold couplings using the Audioscan Verifit 1 and Verifit 2 fitting systems, followed by measurements in the respective couplers.Twenty-one adults (mean age = 67 yr, range = 19–78) with typical aural anatomy (as determined by measures of impedance and otoscopy) participated in this study, leading to a sample size of 42 ears.Repeatability within RECD and wRECD was assessed for each coupling configuration using a repeated-measures analysis of variance (ANOVA) with test–retest and frequency as within-participants factors. Repeatability between the RECD and wRECD was assessed within each configuration using a repeated-measures ANOVA with test–retest, frequency, and coupler type as within-participants factors. Agreement between the RECD and wRECD was assessed for each coupling configuration using a repeated-measures ANOVA with RECD value, coupler type, and frequency as within-participants factors. Post hoc comparisons with Bonferroni corrections were used when appropriate to locate the frequencies at which differences occurred. A 3-dB criterion was defined to locate differences of clinical significance.Average absolute test–retest differences were within ±3 dB within each coupler and coupling configuration, and between the RECD and wRECD. The RECD and wRECD were in absolute agreement following HA-1-referenced transforms, with most frequencies agreeing within ±1 dB, except at 0.2 kHz for the earmold, and 0.2–0.25 kHz for the foam tip, where the average RECD exceeded the average wRECD by slightly >3 dB.Test–retest repeatability of the RECD (up to 8 kHz) and wRECD (up to 12.5 kHz) is acceptable and similar to previously reported data. The RECD and wRECD are referenced to different couplers, but can be rendered comparable with a simple transform, producing values that are in accordance with the ANSI S3.46-2013 standard.

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