HUMAN PELVIS BUTTRESS SYSTEM AND THE ROLE OF SKELETAL MUSCLES IN ITS FORMATION (REVIEW ARTICLE)

2020 ◽  
pp. 93-100
Author(s):  
Иван Васильевич Гайворонский ◽  
А. А. Родионов ◽  
Геннадий Иванович Ничипорук ◽  
Инга Александровна Горячева ◽  
Мария Георгиевна Гайворонская

В связи с вертикальным положением тела на таз человека действуют такие механические силы, как масса тела, внутренностей, внутрибрюшное давление, тяга мышц, связочного аппарата. Под воздействием этих сил происходит моделирование костных структур - внутренних пластинок губчатого вещества и замыкательных пластинок компактного вещества, наибольшая концентрация которых происходит в местах воздействия сил сжатия и растяжении. Указанные места повышенной плотности костной ткани в составе костного таза являются его контрфорсами. Связующим фундаментом контрфорсной системы таза является крестец, воспринимающий воздействия механических сил и передающих их на тазовые кости. Авторами выделены следующие костные контрфорсы: 1 - пояснично-крестцово-подвздошно-бедренный; 2 - пояснично-крестцово-подвздошно-седалищный; 3 - крестцово-седалищный; 4 - крестцово-бедренный; 5 - крестцово-подвздошнолобковый. Рассматривать контрфорсы таза необходимо с позиций арочных конструкций с обязательным взаимодействием контралатеральных сторон. Арочные конструкции, образованные пояснично-крестцово-подвздошно-бедренным, крестцовобедренным и крестцово-подвздошно-лобковыми контрфорсами, функционируют при вертикальном положении тела, а пояснично-крестцово-подвздошно-седалищные и крестцово-седалищные контрфорсы - при сидячем положении тела. Важнейшую роль в формировании и поддержании костных контрфорсов также играют скелетные мышцы, прикрепляющиеся к костям таза. Они не только изменяют его костную структуру, но и передают напряжение при своем сокращении на другие кости, формируя мышечные контрфорсные системы. В работе доказано наличие следующих костно-мышечных контрфорсов: 1 - наружного и внутреннего подвздошно-бедренного; 2 - наружного и внутреннего запирательнобедренного; 3 - лобково-седалищно-бедренно-большеберцового; 4 - седалищно-большеберцово-малоберцового контрфорсов. Показано, что таз является важнейшей частью опорно-двигательного аппарата человека и стабилизационным кольцом для свободной нижней конечности. In connection with the vertical position of the body, such mechanical forces as body weight, viscera, intra-abdominal pressure, traction of muscles, tendons and ligament apparatus act on the human pelvis. The bone structures - the internal plates of the spongy substance and the end plates of the compact substance, the highest concentration of which occurs at the sites of compression and tension - are modeled under the influence of these forces. The aforementioned places of increased bone density in the composition of the bone pelvis are its buttresses. The connecting foundation of the buttress system of the pelvis is the sacrum, perceiving the effects of mechanical forces and transmitting them to the pelvic bones. The authors distinguished the following bone buttresses: 1 - lumbo-sacral-iliac-femoral; 2 - lumbo-sacral-iliac-sciatic; 3 - sacro-sciatic; 4 - sacro-femoral; 5 - sacro-iliac-pubical. It is necessary to consider buttresses of the pelvis from the position of arched structures, with the obligatory interaction of the contralateral sides. Arched structures formed by the lumbo-sacral-iliac-femoral, sacro-femoral and sacro-iliac-pubic buttresses function when the body is in vertical position, and the lumbo-sacral-iliac-sciatic and sacroiliac buttresses when the body is in seated position. Skeletal muscles attached to the bones of the pelvis also play an important role in the formation and maintenance of bone buttresses. They not only change its bone structure, but during their contraction also transmit tension to other bones, forming muscle buttress systems. In the work, the presence of the following musculoskeletal buttresses is proved: 1 - the external and internal ileo-femoral; 2 - external and internal obturator-femoral; 3 - pubic-sciaticfemoral-tibial; 4 - sciatic-tibial-fibular buttresses. It is shown that the pelvis is the most important part of the human musculoskeletal system and the stabilization ring for the free lower limb.

2021 ◽  
Vol 27 (1) ◽  
pp. 4-11
Author(s):  
Nikolay Mikhailovich Vladimirov ◽  

Skeletal muscles are the largest organ in the human body, making up 40–50% of the total human body weight. This work is devoted to the study of physical activity on the athlete’s body. Given that the muscular system is more multifunctional than previously thought, and is able to aff ect many systems of the body through the synthesis and secretion of cytokines-classical regulators of the immune system, classifi ed as myokines. In this review article, we summarize our current knowledge of the main identifi ed and characterized myokines, focusing on their biological activity and functions. Through regular exercise, muscle-induced factors called myokines can exert and play an important role in protecting against many diseases.


Author(s):  
Eran Linder-Ganz ◽  
Amit Gefen

Deep tissue injury (DTI) is a serious and potentially deadly type of pressure ulcers, which initiate in deep muscle tissue under bony prominences of immobilized patients, and progress outwards towards the skin with no clear visual indications of the injury at the surface of the body. It had been suggested that DTI appear in muscle tissue first, due to the dense capillary vasculature in skeletal muscles which is susceptible to obstruction and occlusion by mechanical forces [1–3]. Though mechanical forces may cause capillaries to collapse and thus induce ischemic conditions in adjacent muscle cells [2], some investigators stipulated that ischemia alone cannot explain the etiology of DTI, and so, other mechanisms, particularly excessive cellular deformations must be involved [1]. We hypothesize that physiological levels of stresses and strains in muscle tissue under bony prominences — even when muscles are highly loaded as during sitting — do not cause complete closure of muscle capillaries, and therefore, do not cause an acute ischemia in muscles. If this is indeed the case, then ischemia cannot be the only factor contributing to DTI onset. In order to test our hypothesis, we developed a finite element (FE) model of the microstructure of skeletal muscle, at the level of muscle fascicles, and employed the model to determine the stress and strain levels required for causing partial and complete closure of capillaries.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1517-1523
Author(s):  
Vriti Pursnani ◽  
Amit Reche ◽  
Gaurav Majumdar ◽  
Prerna Gautam ◽  
Kumar Gaurav Chhabra ◽  
...  

Coronavirus disease 2019 had caused a pandemic leading to over 6M positive cases worldwide out of which 3.73 lac are demised (until when the article was written). Its first outbreak was seen in Wuhan, China. In the Indian scenario, we have a total of 2 lac cases out of which 5,679 have been deceased (until when the article was written). Due to the high transmissibility of this disease, the entire country is under lockdown to prevent the spread of the virus. The main etiology of this virus is the severe acute respiratory syndrome coronavirus-2(SARS-CoV-2). This affects the respiratory system leading to cough, shortness of breath, and fever. There have been cases with mild or no symptoms reported, but the cause of death is due to the virus. This helps us understand the diagnosis, epidemiology, symptoms, and pathophysiology about the virus, which can help in treatment modalities. An autopsy is one of the methods by which we can understand the systematic involvement other than the respiratory system. Various pathological, microbiological changes can occur in the other organs. Even though the person is deceased, the virus is highly infectious can cause the spread through body fluids. Proper care must be taken while handling the body and performing the procedure. This review article aims to focus on the autopsy findings found in various cases to study the disease pathophysiology of the SARS-CoV-2. This article also helps us understand the guidelines that have been put forward by WHO and CDC must be followed regarding the specification required in the autopsy room; PPE’s to be worn, human waste and fluid disposal, body transportation. Proper personal hygiene must be maintained while handling the COVID-19 patients; this can lead to less susceptibility of acquiring the disease.


2016 ◽  
Vol 10 (1) ◽  
pp. 636-645 ◽  
Author(s):  
Yusuf H. Mirza ◽  
Rosamond Tansey ◽  
Mohamed Sukeik ◽  
Mohammed Shaath ◽  
Fares Sami Haddad

An increasing demand for lower limb arthroplasty will lead to a proportionate increase in the need for revision surgery. A notable proportion of revision surgery is secondary to periprosthetic joint infections (PJI). Diagnosing and eradicating PJI can form a very difficult challenge. An important cause of PJI is the formation of a bacterial biofilm on the implant surface. Our review article seeks to describe biofilms; their definitions and formation, common causative bacteria, prophylactic and therapeutic antibiotic therapy.


2021 ◽  
Author(s):  
Siyi Xie ◽  
Chushan Fang ◽  
Yujie Gao ◽  
Jie Yan ◽  
Lina Luo ◽  
...  

Abstract Background: Skeletal muscle is composed of bundles of myofibers ensheathed by extracellular matrix networks. Malformation of skeletal muscle during embryonic development results in congenital myopathies. Disease mechanisms of congenital myopathies remain unclear. PINCH, an adaptor of focal adhesion complex, plays essential roles in multiple cellular processes and organogenesis. Elucidation of the molecular mechanisms underlying skeletal myogenesis will offer new insights into pathogenesis of myopathies.Methods: We generated muscle-specific PINCH knock-out mice to study the functional role of PINCH in skeletal myogenesis. Histologic and Transmission Electron Microscopy analysis demonstrated that Impaired myogenic differentiation and maturation in mice with PINCH1 being ablated in skeletal muscle progenitors, and Ablation of PINCH1 and PINCH2 resulted in reduced size of muscle fibers and impaired multinucleation; Cell culture and immunostaining showed that defects in myoblast fusion and cytoskeleton assembly in PINCH double mutant mice; Western blotting showed that defects in expression of cytoskeleton proteins and proteins involved in myogenesis in DMUT skeletal muscles.Results: Double ablation of PINCH1 and PINCH2 resulted in early postnatal lethality with reduced size of skeletal muscles and detachment of diaphragm muscles from the body wall. Myofibers of PINCH mutant myofibers failed to undergo multinucleation and exhibited disrupted sarcomere structures. The mutant myoblasts in culture were able to adhere to newly formed myotubes, but impeded in cell fusion and subsequent sarcomere genesis and cytoskeleton organization. Consistent with this, expression of integrin β1 and some cytoskeleton proteins, and phosphorylation of ERK and AKT were significantly reduced in PINCH mutants. Expression of MRF4, the most highly expressed myogenic factor at late stages of myogenesis, was abolished in PINCH mutants, that could contribute to observed phenotypes. In addition, mice with PINCH1 being ablated in myogenic progenitors exhibited only mild centronuclear myopathic changes, suggesting a compensatory role of PINCH2 in myogenic differentiation, indicating a critical role of PINCH proteins in myogenic differentiation.Conclusion: Our results demonstrated an essential role of PINCH in skeletal myogenic differentiation.


Author(s):  
Jyoti M. Ganer ◽  
Umapati C. Baragi

Women have special dietary needs during each stage of her lives, including adolescence, pregnancy, breast feeding and menopause. During pregnancy the mother’s nutrition bears a great impact on the foetus’s growth and its future. Ayurveda lays great emphasis on ensuring holistic nutrition. A combination of Ahara (diet), Vihara (regimen), Vichara (emotions/thoughts) and Aushadha (medications) have been given great significance in Ayurveda in antenatal care called as Garbhini Paricharya (Antenatal care). Diet comprises the most important component of Garbhini Paricharya. Ayurveda advises congenital diet and regimen throughout the pregnancy. It also stresses on the healthy state of mind and body to beget healthy progeny. Milk and ghee stand out as the most common in the pregnant diet that Ayurveda advises. The idea of this is to provide optimum amount of protein and fat to the body. In addition, it provides right amount of calcium and vitamins for the pregnant mother helping in sustaining a comfortable lactation. In this review article a designed protocol of the month wise diet advised by various ancient Ayurvedic physicians, which can be modified according to the age, season, place, constitution and the digestive fire of the pregnant woman has been presented.


2020 ◽  
Vol 1 (3) ◽  
pp. 21-26
Author(s):  
Magdalena WASILEWSKA ◽  
Karolina ŁAPETA ◽  
Patryk TULKE ◽  
Patryk TULKE ◽  
Patryk TULKE ◽  
...  

Introduction: Muscle stretching is defined as a approach of performing exercises which improve flexibility of the muscles. This is an important aspect of normal human function because it can influence the amplitude and economy of a movement. The aim: The aim of the study was to reveal the role of stretching among climbers. Material and methods:The study group consisted of 88 rock climbers, in the range of 24 to 84 years old, including 34 women (39%) and 54 men (61%). The study was conducted using anonymous electronic questionnaire. Results: The question about the level of advancement in climbing "beginner level" was declared by 22 (25%) climbers, "medium level" - 31 (35%), "intermediate level" - 23 (26%) and "advanced" - 12 (14%). The most frequent parts of the body stretching through climbers are the shoulder and upper limb - 42 (48%), lower limb - 27 (31%) and pelvis 19 (21%). Stretching after each training was used by 39 (44%) climbers, less than once a week 11 (12%) climbers. C o n c l u s i o n s : 1 . S t r e t c h i n g minimizes injuries in climbing. 2. Stretching is used as part of the warm-


2021 ◽  
Vol 38 (1) ◽  
pp. 72-86
Author(s):  
B. V. Golovskoy ◽  
M. D. Berg ◽  
I. A. Bulatova ◽  
E. I. Voronova ◽  
Ya. B. Khovaeva

Chronic non-infectious diseases are the leading cause of premature death according to the WHO data. This review considers the evolution of studying and modern views of domestic and foreign authors on the role of skeletal muscles in maintaining health and preventing chronic non-infectious diseases. An idea regarding the nervous and reflex influence from the working muscles on both individual organs and the body as a whole is presented. The role of myokines, specific proteins produced by skeletal muscles, capable of influencing the state of many organs and systems, is described.


Conexões ◽  
2019 ◽  
Vol 17 ◽  
pp. e019001 ◽  
Author(s):  
Luiz Uehara ◽  
Chris Button ◽  
Keith Davids

Objective: This review article delineates some important theoretical concepts that inform sport expertise acquisition studies. In particular, the principles of ecological psychology and dynamical systems theory have united together to form the ecological dynamics, a framework that provides the perfect platform through which to study the role of socio-cultural constraints upon sport expertise. Methodology: The body of information collected for this article was primarily extracted from peer- reviewed articles and academic books. This review article used Brazilian soccer as the case study. Results and discussion: Whilst the sports expertise literature has been guilty of somewhat polarising the influence of either practice or inherited attributes upon motor learning there are nonetheless many useful lessons to be learnt from this review article. For example, sport expertise development takes place over many years and includes numerous formal and informal pathways that athletes can take to excel.  Conclusion: The constraints-led approach has been promoted as a framework for understanding how people acquire perceptual-motor skills for sport and physical activities. On a practical level, this approach suggests that the major role of the coach or teacher is to manipulate key constraints in order to facilitate discovery of functional movement behavior.


2020 ◽  
Vol 27 ◽  
Author(s):  
Suvadeep Mal ◽  
Ashish Ranjan Dwivedi ◽  
Vijay Kumar ◽  
Naveen Kumar ◽  
Bhupinder Kumar ◽  
...  

: Peroxisome proliferator-activated receptor (PPAR), a ligand dependant transcription factor, is a member of nuclear receptor superfamily. PPAR exists in three isoforms i.e. PPAR alpha (PPARα), PPAR beta (PPARβ), and PPAR gamma (PPARγ). These are multi-functional transcription factor and help in regulating inflammation, diabetes type 2, lipid concentration in the body, metastasis, and tumor growth or angiogenesis. Activation of PPARγ causes inhibition of growth of cultured human breast, gastric, lung, prostate, and other cancer cells. PPARγ is mainly involved in fatty acid storage, glucose metabolism, and homeostasis and adipogenesis regulation. A large number of natural and synthetic ligands bind to PPARγ and modulate its activity. Ligands such as thiazolidinedione, troglitazone, rosiglitazone, pioglitazone effectively bind to PPARγ however, most of these were found to display severe side effects such as hepatotoxicity, weight gain, cardiovascular complications and bladder tumor. Now the focus is shifted towards the development of dual-acting or pan PPAR ligands. The current review article describes the functions and role of PPARγ in various disease states. In addition, recently reported PPARγ ligands and pan PPAR ligands were discussed in detail. It is envisaged that the present review article may help in the development of potent PPAR ligands with no or minimal side effects.


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