POSSIBILITIES FOR PREDICTING OF CARDIAC ARRHYTHMIAS AND CONDUCTIVITY DISORDERS IN FORMER ATHLETES

2020 ◽  
pp. 131-136
Author(s):  
О. Б. Крысюк ◽  
А. Г. Обрезан ◽  
С. Ф. Задворьев ◽  
А. А. Яковлев
Keyword(s):  
Atrial Fibrillation ◽  
Risk Factor ◽  
Prospective Studies ◽  
Cardiac Arrhythmias ◽  
Medical Records ◽  
Cardiac Rhythm ◽  
Prognostic Model ◽  
Premature Ventricular Contractions ◽  
Former Athletes ◽  
The Relationship

Для выявления характера взаимосвязи спортивного анамнеза лиц, практиковавших в прошлом интенcивные физические нагрузки, и выявленных у них нарушений ритма сердца и внутрисердечной проводимости был проведен ретроспективный анализ медицинских документов 39 мужчинветеранов спорта (средний возраст - 61,6±11,3 года, средняя длительность постспортивного периода - 23,9±17,3 года, средний стаж соревновательной деятельности - 20,1±9,9 года), имеющих установленные сердечно-сосудистые заболевания. Проведено скрининговое обследование на предмет нарушений ритма и проводимости сердца, эхокардиографическое исследование. Выявлено, что распространенность устойчивых пароксизмов фибрилляции предсердий составила 42% в совокупной выборке, увеличиваясь с повышением уровня спортивной квалификации. Желудочковые нарушения ритма высокой градации выявлены у 14% обследованных. Лишь три параметра были достоверно связаны с риском нарушений ритма у ветеранов спорта: уровень спортивной квалификации, наличие генерализованного атеросклероза (антириск-фактор), возраст. Риск нарушений ритма у ветеранов спорта на 43% определяется указанными факторами. Был предложен алгоритм скрининга нарушений ритма у ветеранов спорта на основе клинических данных. Необходимы дальнейшие проспективные наблюдения для валидации алгоритма. In order to analyze the relationship between the athletic qualification and syndrome of cardiac rhythm and conductivity disturbances in former athletes, a retrospective analysis of medical records of 39 male former athletes with cardiovascular complaints (mean age 61,6±11,3 years, mean duration of career in sports 23,9±17,3 years, mean duration of post-athletic period 20,1±9,9 years) was carried out. The patients were screened for cardiac arrhythmias and underwent echocardiography. The overall prevalence of sustained paroxysms of atrial fibrillation was 42%, increasing with the athletic qualification. Ryan grade 4 b -5 premature ventricular contractions were found in 14% of patients. 3 parameters were found to be the independent predictors of arrhythmias in former athletes, i. e. athletic qualification, multifocal atherosclerosis (as an anti-risk factor), and age. The coefficient of determinance for the created prognostic model reached 43%. Further prospective studies are needed to validate an algorithm.

Abstract P116: Chronic Kidney Disease And Cardiac Arrhythmias: A Systematic Review and Meta-analysis

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Esther D Kim ◽  
Ning Ding ◽  
Junichi Ishigami ◽  
Xuejuan Ning ◽  
Yijing Feng ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Systematic Review ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Prospective Studies ◽  
Cardiac Arrhythmias ◽  
Meta Analysis ◽  
Case Control ◽  
Cross Sectional ◽  
The Relationship

Background: Chronic kidney disease (CKD) strongly predicts sudden cardiac death and may elevate the risk of certain cardiac arrhythmias like atrial fibrillation; however, the relationships between CKD and various types of arrhythmia are not well-characterized. Methods: We performed a systematic review and meta-analysis by searching Embase and PubMed for prospective, cross-sectional, and case-control studies examining the associations of two key CKD measures, estimated glomerular filtration rate (eGFR) and albuminuria, with arrhythmias in adults that were published until July 2018. We performed qualitative assessment of studies using the Newcastle Ottawa Quality Assessment Scale. We pooled the results using random-effects models. Results: Among 16,245 articles, we identified 34 prospective (n=24,213,233), 21 cross-sectional (n=253,328), and 4 case-control (n=1,694) studies that included diverse study populations from 19 countries and were mostly high quality. Most prospective studies examined the relationship between eGFR and atrial fibrillation (AF), and demonstrated that lower eGFR was associated with a higher risk of AF (pooled hazard ratio [HR] 1.72 [95% CI: 1.30, 2.27] comparing reduced vs. referent eGFR groups)[ Figure ]. A few studies examined albuminuria and demonstrated its associations with AF (pooled HR 2.16 [95% CI: 1.74, 2.67] comparing high vs. low albuminuria). Results were similar for cross-sectional studies. Four prospective studies reported a higher incidence of ventricular tachycardia resulting in ICD shock according to reduced eGFR (pooled HR 2.32 [95% CI: 1.74, 3.09] comparing reduced vs. referent eGFR groups). Limited number of studies examined other types of arrhythmia. Conclusion: We identified robust data on the relationship between CKD (eGFR and albuminuria) and AF. Reduced eGFR was associated with life-threatening ventricular arrhythmias. Our review highlights the need of future studies for non-AF arrhythmias, especially in the context of albuminuria.

scholarly journals Rates of Cardiac Rhythm Abnormalities in Patients with CKD and Diabetes

2019 ◽  
Vol 14 (4) ◽  
pp. 549-556 ◽  
Author(s):  
Nazem Akoum ◽  
Leila R. Zelnick ◽  
Ian H. de Boer ◽  
Irl B. Hirsch ◽  
Dace Trence ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cardiac Arrhythmias ◽  
Ventricular Arrhythmias ◽  
Cardiac Rhythm ◽  
Cardiac Monitoring ◽  
Premature Ventricular Contractions ◽  
Mortality And Morbidity ◽  
Conduction Abnormalities ◽  
Patients With Diabetes ◽  
New Diagnosis

Background and objectivesCardiac arrhythmias increase mortality and morbidity in CKD. We evaluated the rates of subclinical arrhythmias in a population with type 2 diabetes and patients with moderate to severe CKD who were not on dialysis.Design, setting, participants & measurementsThis is a prospective observational study, using continuous ambulatory cardiac monitors to determine the rate of atrial and ventricular arrhythmias, as well as conduction abnormalities in this group.ResultsA total of 38 patients (34% women), with mean eGFR of 38±13 ml/min per 1.73 m2, underwent ambulatory cardiac monitoring for 11.2±3.9 days. The overall mean rate of any cardiac arrhythmia was 88.8 (95% confidence interval [95% CI], 27.1 to 184.6) episodes per person-year (PY). A history of cardiovascular disease was associated with a higher rate of detected arrhythmia (rate ratio, 5.87; 95% CI, 1.37 to 25.21; P<0.001). The most common arrhythmia was atrial fibrillation, which was observed in two participants with known atrial fibrillation and was a new diagnosis in four patients (11%), none of whom experienced symptoms. Overall, atrial fibrillation episodes occurred at a rate of 37.6 (95% CI, 2.4 to 112.3) per PY. Conduction abnormalities were found in eight patients (21%), a rate of 26.5 (95% CI, 4.2 to 65.5) per PY. Rates of ventricular arrhythmias were low (14.5 per PY; 95% CI, 4.3 to 32.0) and driven by premature ventricular contractions.ConclusionsCardiac rhythm abnormalities are common in patients with diabetes with moderate to severe CKD not requiring dialysis. Rates of atrial fibrillation are high and episodes are asymptomatic. Future studies are needed to determine the role of screening and upstream therapy of cardiac arrhythmias in this group.

scholarly journals Holter Monitoring and Loop Recorders: From Research to Clinical Practice

2016 ◽  
Vol 5 (2) ◽  
pp. 136 ◽  
Author(s):  
Alessio Galli ◽  
Francesco Ambrosini ◽  
Federico Lombardi ◽  
◽  
◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Cardiac Arrhythmias ◽  
Cardiac Rhythm ◽  
Cryptogenic Stroke ◽  
Heart Rhythm ◽  
Holter Monitoring ◽  
Cardioverter Defibrillator ◽  
Proven Efficacy ◽  
Prolonged Monitoring ◽  
Monitoring Technologies

Holter monitors are tools of proven efficacy in diagnosing and monitoring cardiac arrhythmias. Despite the fact their use is widely prescribed by general practitioners, little is known about their evolving role in the management of patients with cryptogenic stroke, paroxysmal atrial fibrillation, unexplained recurrent syncope and risk stratification in implantable cardioverter defibrillator or pacemaker candidates. New Holter monitoring technologies and loop recorders allow prolonged monitoring of heart rhythm for periods from a few days to several months, making it possible to detect infrequent arrhythmias in patients of all ages. This review discusses the advances in this area of arrhythmology and how Holter monitors have improved the clinical management of patients with suspected cardiac rhythm diseases.

Cardiac Rhythm and Conduction Disturbances

2019 ◽  
pp. 197-206
Author(s):  
Yahaira Ortiz Gonzalez ◽  
Fred Kusumoto
Keyword(s):  
Atrial Fibrillation ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Cardiac Arrhythmias ◽  
Cardiac Rhythm ◽  
Hemodynamic Instability ◽  
Conduction Disturbances ◽  
Ventricular Tachycardias

Patients in the intensive care unit (ICU) are exposed to several physiologic stressors that may trigger cardiac arrhythmias and lead to hemodynamic instability. Prompt recognition and initiation of appropriate therapies for arrhythmias is important because critically ill patients with arrhythmias (compared to patients without arrhythmias) have longer hospitalizations and higher mortality (30.8% vs 21.2%). Arrhythmias are classified as tachyarrhythmias or bradyarrhythmias. The most common sustained arrhythmias are supraventricular; atrial fibrillation is the most prevalent. Among the ventricular arrhythmias, up to 50% are monomorphic ventricular tachycardias.

scholarly journals Prevalence of Gastroesophageal Reflux in Infants with Recurrent Brief Apneic Episodes

1999 ◽  
Vol 6 (5) ◽  
pp. 401-404 ◽  
Author(s):  
Shahid Sheikh ◽  
Thomas C Stephen ◽  
Barbara Sisson
Keyword(s):  
Risk Factor ◽  
Gastroesophageal Reflux ◽  
Medical Records ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Acid Reflux ◽  
Diagnostic Dilemma ◽  
Esophageal Ph ◽  
Life Threatening ◽  
The Relationship

BACKGROUND: Apnea in an infant can be a diagnostic dilemma for the treating pediatrician. It is suggested that in some infants, gastroesophageal reflux (GER) might be a factor in the pathogenesis of apnea, although its role as a cause of apnea is still controversial.OBJECTIVE: To evaluate the prevalence of GER in infants presenting with recurrent brief apneic periods.PATIENTS AND METHODS: A retrospective review of the medical records of all the infants who underwent prolonged esophageal pH studies for brief apneic episodes (n=105) at the Kosair Children’s Hospital in the six years from January 1992 to December 1997 was performed. Infants presenting with apparent life-threatening episodes were excluded.RESULTS: Of 105 infants, 72 (68.6%) were younger than two months of age and 22 (21%) were born preterm. Fifty of 105 infants (47.6%) had positive esophageal pH studies for acid reflux. Among infants with positive pH studies, only 21 (42%) had associated gastrointestinal or feeding complaints.CONCLUSION: GER is present in a large number of infants presenting with brief apneic episodes. Though the relationship between the two is still not fully established, GER may be a significant risk factor for such apneic episodes in infants.

scholarly journals Orthostatic hypotension and atrial fibrillation: is there a relationship?

2021 ◽  
Vol 27 (4) ◽  
pp. 409-414
Author(s):  
O. N. Antropova ◽  
I. V. Osipova ◽  
G. G. Efremushkin
Keyword(s):  
Atrial Fibrillation ◽  
Cardiovascular Disease ◽  
Risk Factor ◽  
Elderly Patients ◽  
Orthostatic Hypotension ◽  
Venous Return ◽  
Upright Position ◽  
Cerebrovascular Complications ◽  
All Cause Mortality ◽  
The Relationship

Orthostatic hypotension (OH), a possible marker of autonomic dysfunction, reflects the inability of reflex cardiovascular mechanisms to compensate for the fall in venous return in the upright position. This is a manifestation of structural and functional abnormalities of the cardiovascular system. Significance of the orthostatic hypotension is underestimated, while it is associated with all-cause mortality and cardiovascular disease. The article reviews the relationship between atrial fibrillation (AF) and OH. The pathogenetic mechanisms of OH are considered, including various subgroups, e. g. elderly patients. The article also discusses the relationship between OH, AF and cerebrovascular complications. Available evidence suggests that impaired orthostatic hemodynamic response should be considered as a new risk factor for AF. Further research is needed for better understanding of the association between AF and OH, as well as their management.

scholarly journals Sleep Disorders and Atrial Fibrillation: Current Situation and Future Directions

2018 ◽  
Vol 7 ◽  
pp. e1416
Author(s):  
Alireza Sepehri Shamloo ◽  
Arash Arya ◽  
Nikolas Dagres ◽  
Gerhard Hindricks
Keyword(s):  
Atrial Fibrillation ◽  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Disorders ◽  
Incidence Rates ◽  
Future Directions ◽  
Related Literature ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome ◽  
The Relationship

Atrial fibrillation (AF) is a growing health problem worldwide. In recent years, there has been a rising interest in the relationship between sleep disorders and AF. Several studies have reported higher prevalence and incidence rates of AF in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). However, some believe that OSAHS is not a risk factor for AF; but AF, by itself, is regarded as one of the possible triggers for OSAHS. In this study, the related literature investigating the association between OSAHS and AF was reviewed, and then the possible mechanisms of this interplay were discussed. To conclude, recommendations for further research in this field were presented to researchers and some points were highlighted for physicians.[GMJ.2018;7:e1416]

scholarly journals Influence of risk factors and polymorphism of casq2 gene on development of atrial fibrillation in combination with sick sinus node syndrome

2018 ◽  
Vol 96 (9) ◽  
pp. 804-808
Author(s):  
Evgeniy A. Archakov ◽  
R. E. Batalov ◽  
S. V. Popov ◽  
A. V. Smorgon ◽  
E. F. Muslimova ◽  
...  
Keyword(s):  
Risk Factors ◽  
Atrial Fibrillation ◽  
Left Atrium ◽  
Cardiac Arrhythmias ◽  
Fragment Length Polymorphism ◽  
Myocardial Hypertrophy ◽  
Sinus Node ◽  
Heart Rhythm ◽  
Relationship Of ◽  
The Relationship

The aim of the study was to evaluate the influence of risk factors on the development of a combination of atrial fibrillation and sick sinus node syndrome and to determine the relationship of these cardiac arrhythmias to the polymorphism of the CASQ2 gene. The study included 95 patients, mean age 61.1 ± 14.3 years; Of them men - 48 (50.5%), with AF - 38 (40.0%), SSS - 17 (17.9%) and their combination - 40 (42.1%). Patients are divided into 3 groups, depending on the type of heart rhythm disturbance. The analysis of polymorphism rs6684209 of the gene of calsequestrin CASQ2 in all patients by the method of analysis of restriction fragment length polymorphism was performed. The size of the left atrium, ejection fraction, the presence of chronic heart failure (CHF), the presence of dyslipidemia, the increased body mass index (BMI), myocardial hypertrophy of the left ventricle were evaluated as factors influencing the development of the tachy-brady syndrome. It was revealed that all patients in the first group had CHF (y = 4.44, p = 0.03, x = 4.88, p = 0.02), and patients with CHF FC II significantly prevailed. Dyslipidemia in patients with a combination of two types of heart rhythm disturbances is much more common (x = 6.24, p = 0.01) than in patients with only AF. The BMI was significantly different in the first and third groups (t = 2.1, CC = 55, p = 0.03). Analysis of the frequency distribution ofgenotypes of the CASQ2 gene and alleles did not reveal the presence of statistically significant differences between the groups studied. According to the research on the development of a combination of two cardiac arrhythmias of AF and SSS, such factors as CHF, BMI and the presence of dyslipidemia influence. The relationship between the development of the tachy-brady syndrome and the genetic polymorphism of the protein calsequestrin in the sample was not revealed. A population with a heterozygous type of inheritance of a protein called calsequestrin is less prone to developing a dilatation of the left atrium.

scholarly journals VARIABILITY OF BLOOD PRESSURE IN COMORBIDITY OF ARTERIAL HYPERTENSION AND ATRIAL FIBRILLATION

2021 ◽  
Vol 19 (5) ◽  
pp. 481-488
Author(s):  
S. S. Boev ◽  
◽  
N. Ya. Dotsenko ◽  
I. A. Shekhunova ◽  
L. V. Gerasimenko ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Blood Pressure ◽  
Risk Factor ◽  
Cardiovascular Risk ◽  
Arterial Hypertension ◽  
Blood Pressure Variability ◽  
Decisive Role ◽  
Additional Contribution ◽  
The Relationship ◽  
Risk Reducing

Background. Arterial hypertension plays a decisive role in the development of atrial fibrillation, being the most important risk factor. Purpose. Analyze the literature on modern concepts of the relationship between blood pressure variability and atrial fibrillation. Material and methods. We analyzed 53 literature sources. Results. Information about the modern mechanisms of atrial fibrillation formation in arterial hypertension has been obtained. Approaches to the choice of antihypertensive therapy in patients with arterial hypertension and atrial fibrillation have been described. Conclusions. Based on the studies presented in the literature, it was found that blood pressure variability has an additional contribution to cardiovascular risk. Reducing blood pressure variability can be added as one of the important strategies in the treatment of arterial hypertension and atrial fibrillation.

scholarly journals Atrial fibrillation: a new facet of diabetes mellitus in the XXI century

2011 ◽  
Vol 14 (1) ◽  
pp. 53-60 ◽  
Author(s):  
Andrey Alexeevich Aleksandrov ◽  
M N Yadrikhinskaya ◽  
Svetlana Semenovna Kukharenko
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Atrial Fibrillation ◽  
Congestive Heart Failure ◽  
Risk Factor ◽  
Life Expectancy ◽  
Cardiac Rhythm ◽  
Cardiovascular Complications ◽  
Cardiac Insufficiency

Congestive heart failure, diabetes mellitus, and ciliary arrhythmia are three epidemic cardiovascular conditions threatening the mankind in the XXIcentury. Ciliary arrhythmia is the commonest disturbance of cardiac rhythm characterized by inability of the atrium to maintain coordinated contractions.The importance of ciliary rrhythmia as a problem facing public heath services is underlain by its role as a risk factor of disturbed cerebralcirculation and severe cardiac insufficiency, the two most serious and costly cardiovascular complications influencing life expectancy of the affectedsubjects.

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