scholarly journals Profil Pasien Stroke Hemoragik yang Dirawat di ICU RSUP Prof. Dr. R.D. Kandou Manado Periode Desember 2014 sampai November 2015

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Maria Estefina Siwi ◽  
Diana Lalenoh ◽  
Harold Tambajong
Keyword(s):  
Mortality Rate ◽  
Blood Vessels ◽  
Medical Record ◽  
Cause Of Death ◽  
Cerebral Edema ◽  
Hemorrhagic Stroke ◽  
Stroke Mortality ◽  
Probability Sampling ◽  
The Brain ◽  
Very High

Abstract: Hermorrhagic stroke is a disease caused by rupture of blood vessels of the brain that causes bleeding intro the brain parenchym tissue, cerebrospinal space around the brain or combination of both. Cause of death from hemorrhagic stroke is presence of complications or other comorbodities, like cerebral edema were reported the highest cause of death of hemorrhagic stroke. This study aimed to determine the profile of patients with hemorrhagic stroke in ICU, using descriptive retropective method. The samples were Prof. Dr. R.D. Kandou Manado ICU’s patients with hemorrhagic stroke based on the data in the medical record from December 2014 – November 2015. Hemorrhagic stroke mortality rate is very high (89%). From total 35 samples were examined, there 4 survivors (11%) and 31 deaths (89%), which consisted of 24 males (69%) and 11 females (31%). Most patients are 45-59 years old.Keywords: hemorrhagic stroke, ICUAbstrak: Stroke hemoragik adalah penyakit yang disebabkan oleh pecahnya pembuluh darah otak yang menyebabkan keluarnya darah ke jaringan parenkim otak, ruang serebrospinalis disekitar otak atau kombinasi keduanya. Penyebab kematian dari stroke hemoragik sendiri adalah adanya komplikasi atau penyakit penyerta lainnya, salah satu contohnya yaitu edema serebri yang dilaporkan merupakan penyebab kematian terbanyak. Penelitian ini bertujuan untuk mengetahui profil pasien stroke hemoragik yang dirawat di ICU RSUP Prof. Dr. R.D. Kandou Manado, menggunakan metode penelitian deskriptif retrospektif. Besar sampel ditentukan dengan metode non probability sampling yaitu purposive sampling. Sampel penelitian adalah pasien ICU RSUP Prof. Dr. R.D. Kandou Manado dengan diagnosa stroke hemoragik berdasarkan data di bagian Rekam Medik periode Desember 2014 sampai November 2015. Angka mortalitas stroke hemoragik sangatlah tinggi (89%). Total 35 sampel yang diteliti dengan 4 orang yang selamat (11%) dan 31 orang meninggal dunia (89%), terdiri dari 24 orang laki-laki (69%) dan 11 orang perempuan (31%). Sebagian besar adalah pasien umur 45-59 tahun.Kata kunci: stroke hemoragik, ruang rawat intensif

scholarly journals Morphological Features Of Microvascular Tissue Of The Brain At Hemorrhagic Stroke

2020 ◽  
Vol 02 (10) ◽  
pp. 53-59
Author(s):  
Kamalovamalika Ilkhomovna ◽  
◽  
Islamov Shavkat Eriyigitovich ◽  
Khaidarov Nodir Kadyrovich ◽  
◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Blood Vessels ◽  
Brain Tissue ◽  
Cerebral Edema ◽  
Hemorrhagic Stroke ◽  
Adverse Outcome ◽  
Morphological Features ◽  
Neuroimmune System ◽  
Younger Age ◽  
The Brain

Hemorrhagic stroke is less common than ischemic stroke and is heavier and in most cases has an adverse outcome in the form of death of a patient or permanent disability.Recently, there has been a tendency to increase the frequency of GI, which is increasingly found at a younger age. GI is based on a rupture of blood vessels, the development of hemorrhage and as a consequence - the formation of cerebral edema, ischemia of brain tissue, violation of the integrity of GBS, imbalance of the neuroimmune system, as well as violation of the function of other systems and organs.

scholarly journals Outcome Predictors of Stroke Mortality in the Neurocritical Care Unit

2020 ◽  
Vol 11 ◽  
Author(s):  
Dmitriy Viderman ◽  
Alpamys Issanov ◽  
Talgat Temirov ◽  
Ewan Goligher ◽  
Philip la Fleur
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Mortality Rate ◽  
Cerebral Edema ◽  
Mortality Risk ◽  
Critically Ill Patients ◽  
Hemorrhagic Stroke ◽  
Neurocritical Care ◽  
Stroke Mortality ◽  
The Mean

Background: Risk factors for medium to long-term mortality after stroke are well-established but predictors of in-hospital stroke mortality are less clearly characterized. Kazakhstan has the highest age-standardized mortality rate from ischemic stroke in the world.Methods: We performed a retrospective analysis of patients with stroke who were admitted over a 3.5-years period to the neurocritical care unit of a tertiary care hospital in Nur-Sultan, Kazakhstan.Results: In total, 148 critically ill patients were included in the analysis (84 ischemic stroke, 64 hemorrhagic stroke). The mean age was 63 years, 45% were male and the mean Glasgow Coma Score (±SD) at baseline was 10.3 (±3.4). The in-hospital mortality rate was similar in patients with ischemic (36%) and hemorrhagic (39%) stroke (HR 0.88, 95%CI 0.48–1.60). Median survival was 38 days (range: 1–89 days) in patients with ischemic stroke and 39 days (range: 1–63 days) in patients with hemorrhagic stroke. Univariable analysis found that patients who had a lower Glasgow Coma Scale, were in coma and who had cerebral edema were more likely to die in-hospital (P = 0.04, 0.02, <0.01, respectively).Conclusions: Our analysis showed that mortality risk in critically ill patients with hemorrhagic stroke was closer to mortality risk in patients with ischemic stroke than has been reported in other analyses. Hypertension, chronic heart failure, ischemic heart disease and atrial fibrillation were the most frequent comorbidities in patients who developed severe (life-threatening) stroke. Coma and cerebral edema on admission appear to be associated with poor outcome. This is the first publication of in-hospital stroke mortality from a Central Asian population and could form the basis for future research including development of risk scores and identifying modifiable risk factors.

scholarly journals Protective actions of des-acylated ghrelin on brain injury and blood–brain barrier disruption after stroke in mice

2016 ◽  
Vol 130 (17) ◽  
pp. 1545-1558 ◽  
Author(s):  
Jacqueline M. Ku ◽  
Mohammadali Taher ◽  
Kai Yee Chin ◽  
Tom Barsby ◽  
Victoria Austin ◽  
...  
Keyword(s):  
Experimental Study ◽  
Brain Injury ◽  
Blood Vessels ◽  
Blood Brain Barrier ◽  
Cause Of Death ◽  
Acylated Ghrelin ◽  
Blood Brain Barrier Disruption ◽  
Protective Actions ◽  
Brain Barrier Disruption ◽  
The Brain

Stroke is a leading cause of death, but treatments are limited. This experimental study reveals that the hormone ghrelin powerfully protects the brain and its blood vessels against injury after stroke, raising the possibility that it could be exploited therapeutically.

scholarly journals Sudden unexpected, unexplained death in epilepsy autopsied patients

2001 ◽  
Vol 59 (1) ◽  
pp. 40-45 ◽  
Author(s):  
Sergio A. Antoniuk ◽  
Lubomira V. Oliva ◽  
Isac Bruck ◽  
Mariana Malucelli ◽  
Silvia Yabumoto ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Cause Of Death ◽  
Cerebral Edema ◽  
Postmortem Examination ◽  
Death Certificates ◽  
Unexplained Death ◽  
Seizure Event ◽  
National Mortality ◽  
Other Information ◽  
Patients With Epilepsy

Sudden unexpected, unexplained death in epilepsy (SUDEP) has been reported to be responsible for 2 to 17% of all deaths in patients with epilepsy. This study was conducted to determine the circumstances of SUDEP and the autopsy findings in these patients. Fifty-three individuals whose cause of death was related to epilepsy were identified and in 30 cases relatives or friends were interviewed about the circumstances of death and other information which allowed to classify the patients as SUDEP or not. The death certificates were also reviewed. We found 20 cases of SUDEP. Most of them were found dead lying on the bed with no evidence of seizure event, and most of them had pulmonary and/or cerebral edema as the cause of death. The incidence and the risk of SUDEP can only be fully ascertained if all sudden deaths had postmortem examination. Consensus in certifying SUDEP cases would allow better accuracy in national mortality rate.

scholarly journals UJI VALIDITAS SIRIRAJ STROKE SCORE, ALGORITMA STROKE GADJAH MADA, SKOR STROKE NUARTHA TERHADAP COMPUTERIZED TOMOGRAPHY SCAN KEPALA DALAM MENENTUKAN JENIS STROKE PADA FASE AKUT

2020 ◽  
Vol 5 (2) ◽  
pp. 9
Author(s):  
Trisna Lestari ◽  
Yuli Artini ◽  
Farida Noor ◽  
Ariebuana Permanaputra ◽  
Claranur Ramadani
Keyword(s):  
Emergency Room ◽  
Computerized Tomography ◽  
Cause Of Death ◽  
Hemorrhagic Stroke ◽  
Surgical Intervention ◽  
Vascular Disorder ◽  
Brain Disorder ◽  
Global Brain ◽  
The Brain ◽  
Tomography Scan

Stroke is a syndrome that is characterized by sudden functional focal and global brain disorder that develops very quickly lasting more than 24 hours (unless there is surgical intervention or bringing death) caused by vascular disorder in the brain (Gofir, 2009). Stroke is the number one cause of serious disability settled worldwide. Stroke is also a leading cause of death worldwide. This research had 87 sample, consisting of 50 men and 37 women. The study was done using patient suspect stroke that enter the emergency room. The analysis result was nuartha’s stroke score has the highest sensitivity and specificity compared to Siriraj Stroke Score and Gadjah Mada Stroke Score. The sensitivity of the Nuartha Stroke Score in diagnosing non hemorrhagic stroke was 94,87 and with a specificity of 94.12%. Whereas for  diagnosing hemorrhagic stroke, nuartha stroke score has a sensitivity of 94,12% and specificity of 94.87%. With an accuracy of 94.64%  

scholarly journals Hybrid Thresholding Method in Detection and Extraction of Brain Hemorrhage on the CT-Scan Image

2021 ◽  
pp. 7-14
Author(s):  
S Sumijan ◽  
Y Yuhandri ◽  
Wendi Boy
Keyword(s):  
Ct Scan ◽  
Blood Vessels ◽  
Hemorrhagic Stroke ◽  
Congenital Abnormalities ◽  
Trigger Factor ◽  
Thresholding Method ◽  
Computed Tomography Images ◽  
Bleeding Area ◽  
The Brain ◽  
Image Slice

Brain bleeding can occur because of the outbreak of the blood vessels in the brain which culminated into hemorrhagic stroke or stroke due to bleeding. Hemorrhagic Stroke occurs when there is a burst of blood vessels result from some trigger factor. Segmentation techniques to Scanner computed tomography images (CT scan of the brain) is one of the methods used by the radiologist to detect brain bleeding or congenital abnormalities that occur in the brain. This research will determine the area of the brain bleeding on each image slice CT - scan every patient, to detect and extract brain bleeding, so it can calculate the volume of the brain bleeding. The detection and extraction bleeding area of the brain is based on the hybrid thresholding method.

Stroke Epidemiology and Impact

2017 ◽  
Author(s):  
Virginia J Howard
Keyword(s):  
United States ◽  
Cause Of Death ◽  
Cerebrovascular Accident ◽  
Respiratory Diseases ◽  
Hemorrhagic Stroke ◽  
The United States ◽  
Common Type ◽  
Stroke Epidemiology ◽  
The Brain ◽  
Brain Ischemic Stroke

A cerebrovascular accident or stroke is an acute disease of blood vessels of the brain. Ischemic stroke is the most common type of stroke, estimated to be about 87% of all strokes. Ten percent are estimated to be intracerebral hemorrhagic stroke (ICH), and 3% subarachnoid hemorrhagic stroke (SAH). Stroke remains the fourth leading cause of death in the United States in 2012, only surpassed by diseases of the heart, cancer, and chronic lower respiratory diseases. Stroke is the 2nd leading cause of death worldwide. This chapter examines the epidemiology and impact of stroke in the United States and globally.

Pulmonary Embolism Vascular Segmentation in CT Angiography

2013 ◽  
Vol 380-384 ◽  
pp. 4192-4196
Author(s):  
Qi Xin Gao ◽  
Huai An Li
Keyword(s):  
Pulmonary Embolism ◽  
Quantitative Analysis ◽  
Drug Therapy ◽  
Mortality Rate ◽  
Blood Vessels ◽  
Acute Pulmonary Embolism ◽  
Treatment Strategies ◽  
Edge Point ◽  
Disease Mortality ◽  
Very High

Pulmonary embolism mortality rate is very high disease, especially for acute pulmonary embolism with other disease mortality. Treatment of pulmonary embolism method is mainly to drug therapy. Pulmonary embolism in the acute phase of drug treatment strategies is mainly for anticoagulation and thrombolysis. Through the lungs scanning, decision of thrombolysis success or fail. This paper puts forward a kind of algorithm that analysis quantitatively the degree of thrombolysis by the computer. Firstly, making use of the Hessians eigenvalue and diffuse equation enhance pulmonary embolism vessel, and then pulmonary embolism vessel segmentation based on a LEVEL-SET. At lastly, According to the eigenvalue of blood vessels, remove the blood vessels edge line, and the rest relevant to edge point. According to the each point of eigenvector and eigenvalue, quantitative analysis of the degree of thrombolysis.

scholarly journals A CASE REPORT OF HEAT STROKE : AN ICEBERG

2015 ◽  
Vol 05 (02) ◽  
pp. 088-091
Author(s):  
Pothukuchi Venkata Krishna ◽  
Venkata Ravikumar Chepuri ◽  
Hema Karnati ◽  
Raghavareddy Yarram
Keyword(s):  
Case Report ◽  
Mortality Rate ◽  
Cerebral Edema ◽  
Heat Stroke ◽  
Neurological Impairment ◽  
Neurological Involvement ◽  
Neurological Damage ◽  
Residual Damage ◽  
Metabolic Disarray ◽  
The Brain

AbstractHeat stroke was first recognized by the Romans in 24 BC. But it took until 1946 for it to be shown that heat stroke could lead to multiorgan damage with hemorrhage and necrosis in the lungs, heart, liver, kidneys, brain and gut with a 10% to 50% mortality rate. Patients may present with neurological impairment of varying degrees and duration, including delirium, lethargy, coma and seizures, Neurological damage is presumably attributable to metabolic disarray, cerebral edema or ischemia. Here we are presenting a case of heat stroke, with coma due to neurological involvement who recovered functionally fully though with some residual damage revealed in computerized tomogram of the brain after conservative management of heat stroke.

scholarly journals Cytokine-Laden Extracellular Vesicles Predict Patient Prognosis after Cerebrovascular Accident

2021 ◽  
Vol 22 (15) ◽  
pp. 7847
Author(s):  
Anthony Fringuello ◽  
Philip D. Tatman ◽  
Tadeusz Wroblewski ◽  
John A. Thompson ◽  
Xiaoli Yu ◽  
...  
Keyword(s):  
Extracellular Vesicles ◽  
Inflammatory Cytokines ◽  
Hemorrhagic Stroke ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Interleukin 7 ◽  
Poor Outcomes ◽  
Patient Prognosis ◽  
The Brain

Background: A major contributor to disability after hemorrhagic stroke is secondary brain damage induced by the inflammatory response. Following stroke, global increases in numerous cytokines—many associated with worse outcomes—occur within the brain, cerebrospinal fluid, and peripheral blood. Extracellular vesicles (EVs) may traffic inflammatory cytokines from damaged tissue within the brain, as well as peripheral sources, across the blood–brain barrier, and they may be a critical component of post-stroke neuroinflammatory signaling. Methods: We performed a comprehensive analysis of cytokine concentrations bound to plasma EV surfaces and/or sequestered within the vesicles themselves. These concentrations were correlated to patient acute neurological condition by the Glasgow Coma Scale (GCS) and to chronic, long-term outcome via the Glasgow Outcome Scale-Extended (GOS-E). Results: Pro-inflammatory cytokines detected from plasma EVs were correlated to worse outcomes in hemorrhagic stroke patients. Anti-inflammatory cytokines detected within EVs were still correlated to poor outcomes despite their putative neuroprotective properties. Inflammatory cytokines macrophage-derived chemokine (MDC/CCL2), colony stimulating factor 1 (CSF1), interleukin 7 (IL7), and monokine induced by gamma interferon (MIG/CXCL9) were significantly correlated to both negative GCS and GOS-E when bound to plasma EV membranes. Conclusions: These findings correlate plasma-derived EV cytokine content with detrimental outcomes after stroke, highlighting the potential for EVs to provide cytokines with a means of long-range delivery of inflammatory signals that perpetuate neuroinflammation after stroke, thus hindering recovery.

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