A STUDY ON TINEA CORPORIS INFECTION IN PATIENTS ATTENDING A TERTIARY CARE HOSPITAL, TIRUPATI

2021 ◽  
pp. 35-37
Author(s):  
V. Pavani Sai Mounika ◽  
B. Mahalakshmi ◽  
CH. Srinivasa Rao ◽  
C. Naresh Kumar
Keyword(s):  
Low Socioeconomic Status ◽  
Tertiary Care ◽  
Trichophyton Mentagrophytes ◽  
Tinea Corporis ◽  
Lower Limbs ◽  
Care Hospital ◽  
Recurrence Rates ◽  
Dermatology Department ◽  
Low Socioeconomic ◽  
Male Predominance

Purpose: Tinea corporis (Ringworm) is a form of Dermatophytosis, which is a supercial fungal infection involving the trunk, legs, arms, commonly seen in countries like India. Although it is non-invasive and curable, its widespread nature and recurrence rates impose an economic burden on society in developing countries like India. This study aims at isolating different species causing this infection and studying their clinical patterns. Method: The study included the samples from the outpatients attending the Dermatology department of SVRRGGH, Tirupati, who were suspected of having Tinea corporis based on the clinical details, during the period from August 2018 to August 2019. The scrapings are examined by KOH mount and inoculated on Sabouraud's Dextrose agar and Dermatophyte test medium. The species are identied by colony morphology, Lactophenol cotton blue mount, biochemical reactions and standard procedures. Results: Out of 110 samples, overall positivity on direct microscopy is 78.2% (82), for Culture is 38.2%(42) and positive for both KOH and Culture are 38(34%). Out of 7 species isolated, the commonest isolate is Trichophyton mentagrophytes 19(45%), followed by Trichophyton rubrum 12(28%). Conclusion: Tinea corporis infections are more common in the 16-30 years age group, most of the patients belonging to low socioeconomic status with male predominance. Trichophyton species are commonly isolated from lesions in the waist and lower limbs, while Microsporum species from lesions on lower limbs. T. mentagrophytes was found to be the most common isolate and T. rubrum in case of extensive lesions.

scholarly journals A MYCOLOGICAL STUDY OF CLINICAL SAMPLES FROM SUSPECTED MYCOSES IN A TERTIARY CARE HOSPITAL

2018 ◽  
Vol 11 (4) ◽  
pp. 267
Author(s):  
Jitendra Chandra Devrari ◽  
Varsha Saxena ◽  
Vidya Pai
Keyword(s):  
Fusarium Species ◽  
Tertiary Care ◽  
Systemic Infection ◽  
Trichophyton Mentagrophytes ◽  
Culture Technique ◽  
Clinical Samples ◽  
Care Hospital ◽  
Superficial Infection ◽  
Male Predominance ◽  
Urease Test

 Objective: The objective of this study was to isolate and identify the fungal agents obtained from clinical samples of suspected mycoses patients attending Yenepoya hospital.Methods: Various clinical samples obtained from patients were subjected to preliminary examination according to standard mycological protocols such as KOH mount, wet mount, Gram’s staining, and Indian ink examination. Causative organisms were identified by macroscopically and microscopically after growth on sabouraud’s dextrose agar (with or without cycloheximide and chloramphenicol) and confirmed by lactophenol cotton blue mount, slide culture technique, urease test, and growth on chrome agar accordingly.Results: Of 274 clinical samples, 125 were culture positive in which the fungal isolates obtained were dermatophytes (all 3 genera), Candida species (including Candida albicans), Fusarium species, Aspergillus fumigatus, and Cryptococcus neoformans. Male predominance was found among the patients being 6:3 male:female ratio.Conclusion: Among the superficial infection, Trichophyton mentagrophytes was found to be predominant isolates; however, in systemic infection, C. albicans was the predominant isolates.

Health Disparity in Complicated Colorectal Cancer

2010 ◽  
Vol 76 (2) ◽  
pp. 164-167 ◽  
Author(s):  
Kimberly C. Bowman ◽  
Parissa Tabrizian ◽  
Dana A. Telem ◽  
Leon Boudourakis ◽  
Celia M. Divino
Keyword(s):  
Colorectal Cancer ◽  
Low Socioeconomic Status ◽  
Low Income ◽  
White Women ◽  
Tertiary Care ◽  
Cancer Recurrence ◽  
Recurrence Rates ◽  
Low Socioeconomic ◽  
Black Patients ◽  
Tertiary Care Institution

The purpose of this study was to assess for disparity within a cohort of patients presenting with complicated colorectal cancer. A retrospective study of 522 patients who underwent surgery for colorectal cancer at a tertiary care institution was performed. Complicated cancer was defined by perforating or obstructing colonic lesions. Statistical analysis was conducted by χ2 test and analysis of variance. Of the 522 patients, 72 patients (14%) presented with complicated colorectal cancer. Blacks in low-income brackets (36 vs 0%, P < 0.001) and those with public insurance (55 vs 16%, P < 0.05) had increased presentation with complicated colorectal cancers as compared with whites. Black (91%) and Hispanic women (86%), when compared with white women (37%) had increased incidence of complicated colorectal cancer ( P < 0.05). Patients in low-income brackets, regardless of race, had increased cancer recurrence rates (57 vs 8%, P < 0.001) compared with patients in average or high-income brackets. Mortality rate was 57 per cent in Hispanic, 29 per cent in white, and 27 per cent in black patients ( P = nonsignificant). Specific targeting of colorectal cancer screening, education, and follow-up programs is imperative for minority women and patients of low socioeconomic status.

scholarly journals An epidemiological study of low back pain in a tertiary care hospital of Jammu, Jammu and Kashmir, India

2017 ◽  
Vol 5 (3) ◽  
pp. 835 ◽  
Author(s):  
Rishabh Gupta ◽  
Shavi Mahajan ◽  
Deepika Dewan ◽  
Rajat Gupta
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Tertiary Care ◽  
Degenerative Disease ◽  
Lower Limbs ◽  
Physical Sign ◽  
Care Hospital ◽  
Low Back ◽  
Male Predominance ◽  
Mode Of Presentation

Background: Backache is a national, personal and clinical problem. It is experienced by most of the population at some time and is a drain on the nation’s resources. Personally, it is distressing because it can remain a major unresolved dilemma and clinically it poses challenges in diagnosis and treatment.Methods: The present cross sectional study was conducted among 200 patients presenting with chronic low back pain, in the OPD of Post Graduate Department of Orthopaedics, Govt. Medical College, Jammu over a period of one year from November 2006 to October 2007.Results: The average age of patients was 38.39 years with slight male predominance. Majority of the patients were non-sedentary workers. In majority of the cases (58%), duration of low backache was from 3 months to 1 year with the average of 25.8 months (2.158 years). The commonest mode of presentation was low back pain with radiation to lower limbs. Seasonal variation in the intensity of pain was observed in 50% of the cases. Tenderness of the spine was the commonest physical sign. Disc degenerative disease was found to be commonest cause of low backache, being present in 72% of the cases.Conclusions: Low back pain is common in 3rd and 4th decade of life. The commonest mode of presentation was low back pain with radiation to lower limbs. Disc degenerative disease was found to be commonest cause of low backache, being present in 72% of the cases.

scholarly journals A study of etiology and epidemiology of onychomycosis from a tertiary care hospital in North India

2021 ◽  
Vol 9 (2) ◽  
pp. 559
Author(s):  
Shivani Tyagi ◽  
Neha . ◽  
Ravinder Kaur ◽  
Deepti Rawat
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Age Groups ◽  
Trichophyton Mentagrophytes ◽  
North India ◽  
Care Hospital ◽  
Candida Spp ◽  
Dermatology Department ◽  
Age Related ◽  
Etiological Agents

Background: Onychomycosis is the fungal infec­tion of nail of which the incidence varies from 0.5-12% in India and around 5% worldwide.Onychomycosis is considered to be gender and age-related disease, being commoner in males and older adults in both genders. Apart from dermatophytes, other fungal agents like yeasts and non-dermatophyte moulds are increasingly being acknowledged as important etiological agents for the same. Our aim was to study the etiology of the nail infections in patients presenting to a dermatology department in a tertiary care hospital in central Delhi.Methods: This study included nail samples from patients of various age groups with suspected onychomycosis attending dermatology clinics in our hospital over a period of 2 years. For all samples, KOH wet mount microscopic examination followed by culture on Sabouraud’s dextrose agar was done. Growth of filamentous fungi and yeast obtained on SDA were identified using conventional microbiology techniques. Statistical analysis was performed using Epitools.Results: Of the total 1061 nail samples received, maximum prevalence seen in patients of age group 21 to 50 years. The positivity of onychomycosis was 57.02%. Out of culture positive samples, 24.62% grew dermatophytes and 75.37% grew non-dermatophytes (31.40% yeasts and 43.97% non-dermatophyte moulds). Trichophyton mentagrophytes was the most common (59.73%) dermatophyte followed by T. rubrum (23.49%) while among non-dermatophyte moulds; Aspergillus niger (20.68%) was the most common followed by A. flavus (16.54%) and others. Common yeasts included Candida spp. (65.79%) and Trichosporon spp. (28.95%).Conclusions: Non- dermatophytes are emerging as major etiological agents of onychomycosis which may be accounted various host factors. So, it becomes important to correctly identify the causative fungi to ensure appropriate treatment.

Livedo Racemosa: Clinical, Laboratory, and Histopathological Findings in 33 Patients

2020 ◽  
pp. 153473461989693
Author(s):  
Marcella Soares Pincelli ◽  
Alejandra Maria Jimenez Echavarria ◽  
Paulo Ricardo Criado ◽  
Gabriela Franco Marques ◽  
Thâmara Cristiane Alves Batista Morita ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Clinical Laboratory ◽  
Tertiary Care ◽  
Clinical Findings ◽  
Lower Limbs ◽  
Clinical Feature ◽  
Care Hospital ◽  
Livedo Racemosa ◽  
Dermatology Department ◽  
Cutaneous Polyarteritis Nodosa

Livedo racemosa is a cutaneous finding characterized by a persistent, erythematous, or violaceous discoloration of the skin, in a broken, branched, discontinuous, and irregular pattern. A retrospective review of 33 cases with clinical diagnosis of livedo racemosa over the past 6 years was evaluated in the dermatology department of a tertiary care hospital. We found predominance in Caucasian women (78.8%); age ranged from 8 to 81 years, with a mean age of 36 years. Livedo racemosa was described as generalized in 12 patients (36.4%), although the main localization was on lower limbs (42%). After laboratory testing and histopathological examinations, 12 patients (36.4%) were classified with idiopathic livedo racemosa; secondary diseases were diagnosis in 21 patients (63.6%), including Sneddon’s syndrome, cutaneous polyarteritis nodosa, systemic lupus erythematosus, and others. Medical history of thrombotic events was described in 8 (24.2%) patients, and also 8 (24.2%) patients had abnormal results for 2 or more thrombophilia laboratory tests. Skin biopsy showed no histological abnormalities in 11 cases (33.3%), thrombosis of dermal blood vessels in 10 (30.3%), intimal/subintimal thickening in 7 (21.2%), and vasculitis in 5 (15.2%). In conclusion, livedo racemosa is a clinical feature that might be correlated to vascular disorders, such as thrombotic and/or hypercoagulable states, autoimmune diseases, and neoplastic diseases, or it can be secondary to specific medications. It is essential to establish a correct approach in cases of livedo racemosa, which includes anamnesis, physical examination, laboratory test, histological examination, and complementary examination according to clinical findings, in order to diagnosis underlying causes.

scholarly journals A clinicomycological study on chronic dermatophytosis in a tertiary care hospital in North India: An observational study

2021 ◽  
Vol 12 (4) ◽  
pp. 374-380
Author(s):  
Rabiya Bashir ◽  
Naina Kala Dogra ◽  
Bella Mahajan
Keyword(s):  
Trichophyton Rubrum ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Sun Exposure ◽  
Trichophyton Mentagrophytes ◽  
The Body ◽  
Tinea Corporis ◽  
Fungal Culture ◽  
Care Hospital ◽  
Chronic Dermatophytosis

Background: Chronic dermatophytosis is a considerable challenge in routine clinical practice. There is, however, scarce information available in the literature on its extent and characteristics. Aim: The aim of this study was to evaluate the host-related factors of chronic dermatophytosis and to identify the common fungal isolates. Methods: The study enrolled a total of 145 cases of chronic dermatophytosis attending the out-patient department of a tertiary care hospital in Jammu from November 2017 through October 2018. A detailed history was taken, followed by a clinical examination and investigations such as routine baseline investigations, an absolute eosinophil count, a wet mount for direct microscopy, and a fungal culture. Results: The most common presentation was tinea corporis with tinea cruris (33.1%), followed by tinea corporis alone. The majority of the patients (54.5%) had more than 20% of the body surface area involved. Most of the patients were manual workers (n = 44; 30.3%). The number of hours of sun exposure varied between 1 to 8.5 hours (mean ± SD: 3.53 ± 1.75 h). The fungal culture was positive in 65 (44.8%) patients. The most frequent isolates were Trichophyton mentagrophytes (53.8%), followed by Trichophyton rubrum (38.5%). Conclusion: We found Trichophyton mentagrophytes the predominant pathogen in chronic dermatophytosis, followed by Trichophyton rubrum, which demonstrates a changing trend as far as the causative organism is considered. Besides, various risk factors for chronicity such as prolonged sun exposure, lack of proper hygiene, wearing tight-fitting synthetic clothes, the use of topical steroids, and non-compliance to treatment were identified.

scholarly journals A Study of Polypharmacy in Patients with Co-Existing Diabetes Mellitus Type II and Hypertension in a Tertiary Care Center

2021 ◽  
Vol 14 (4) ◽  
pp. 1831-1839
Author(s):  
Shaima Zafer Khan
Keyword(s):  
Diabetes Mellitus ◽  
Low Socioeconomic Status ◽  
Care Center ◽  
Tertiary Care ◽  
Care Hospital ◽  
Diabetes Mellitus Type Ii ◽  
Low Socioeconomic ◽  
H2 Blockers ◽  
Study Population ◽  
Prescribing Cascade

Introduction Polypharmacy is most commonly defined as the use of five or more medications daily by an individual. In India, the prevalence of polypharmacy varies from 5.82 % to 93.14% in different states. Concerns about polypharmacy include increased adverse drug reactions, drug interactions, prescribing cascade, and higher costs. Methods It is a non-interventional, observational, descriptive study carried out in 240 patients attending the medicine outpatient department of a tertiary care hospital, over a one-and-a-half-year duration. Results The study was carried out in 240 patients whose mean age was 53.97 ± 7.62 years, out of which 52.5% were male and 47.5% were female. 62% of the study population were from low socioeconomic status and 38 % were from the middle class. The mean duration in years for hypertension and diabetes was 7.1± 4.3years and 7.94+ 4.66 years respectively. Apart from various antihypertensive and antidiabetic medicines prescribed the study population was also prescribed Vitamins (51.6%), Hypolipidemics (42.5%), Miscellaneous (41.6%), Antiplatelets (40%), H2 blockers/PPI (35.8%), and Antibiotics (22.5%). Polypharmacy (5 or more than 5 drugs) was seen in 33.75% of the study population. Conclusion Polypharmacy has been found to be integral in patients suffering from hypertension with coexisting diabetes mellitus and other comorbidities. It is essential to practice judicious prescribing especially in patients with multiple conditions.

scholarly journals A PROSPECTIVE STUDY OF CLINICAL PROFILE OF STROKE IN A TERTIARY CARE HOSPITAL

2016 ◽  
Vol 9 (9) ◽  
pp. 178 ◽  
Author(s):  
Sattanathan K ◽  
Chachu Kuriakose ◽  
Naseem Shifafiya M ◽  
Nelta S Tharakan ◽  
Sambath Kumar R
Keyword(s):  
Low Socioeconomic Status ◽  
Parietal Lobe ◽  
Tertiary Care ◽  
Underlying Disease ◽  
Clinical Profile ◽  
Periventricular White Matter ◽  
Care Hospital ◽  
Circadian Pattern ◽  
Average Delay ◽  
Male Predominance

ABSTRACTObjective: The objective of the work was to study the clinical profile of stroke in a tertiary care hospital.Methods: A prospective observational study on stroke was carried out for a period of 6-month (May 2015 to October 2015). A total of 241 inpatientsfrom Shri Preethi Hospital were incorporated in the study. The data were collected and evaluated by reviewing case files and patient interview.Result and Conclusion: Out of 241 patients, an incidence of ischemic stroke was found to be higher. The occurrence of stroke steeply rises with agewith male predominance. The burden of stroke tends to be more in rural, illiterate, and low socioeconomic status population. The study reveals riskfactors such as sedentary lifestyle, previous and family history of stroke, underlying disease like hypertension, diabetes. The circadian pattern in onsetshowed a significant peak in morning (6 am-12 pm) for Ischemic and afternoon (12 pm-6 pm) for hemorrhagic stroke. Topographic distribution ofcerebral infract and hemorrhage was found to be in parietal lobe and periventricular white matter, respectively. Mostly prescribed medication forischemic and hemorrhagic patients was antihypertensive and mannitol, respectively. The contraindication for thrombolytic therapy was found to below economic status and average delay in time of presentation to hospital. The study highlights the need for aggressive management of traditionalrisk factors, need for extensive work up in patient to find etiologies and need for more active interventions in community for the prevention of stroke.Keywords: Ischemic, Hemorrhagic, Circadian pattern, Antihypertensive.

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