scholarly journals Efektivitas Pengetahuan Keluarga dalam Pemberian Jus Buah Alpukat pada Pasien Hiperkolesterolemia

2021 ◽  
Vol 2 (1) ◽  
pp. 32-38
Author(s):  
Reski Mardana ◽  
Nurhayati Nurhayati
Keyword(s):  
Literature Review ◽  
Search Strategy ◽  
Final Analysis ◽  
Google Scholar ◽  
Blood Cholesterol ◽  
Heart Health ◽  
Cholesterol Levels

Consuming avocado can maintain heart health. Avocados are rich in compounds called beta-sitosterol which have been shown to be effective in lowering blood cholesterol levels. This literature review aimed to analyze the effectiveness of family knowledge in administering avocado juice to hypercholesterolemic patients. The quantitative this study explores evidence published in electronic databases such as Google Scholar and Pubmed, using a search strategy, we identified 4 articles that are objectives potentially and relevant to the research objectives and these articles were included in the final analysis. This study showed the effectiveness of family knowledge in administering avocado juice to hypercholesterolemic patients. in results of research from several articles in in literature review indicate to  family knowledge is effective in administering avocado juice to hypercholesterolemic patients.

scholarly journals Efek Antioksidan pada Teh Hijau terhadap Kadar Kolesterol Darah

2021 ◽  
Vol 9 (2) ◽  
Author(s):  
Brigita T. Tamon ◽  
Murniati Tiho ◽  
Stefana H. M. Kaligis
Keyword(s):  
Literature Review ◽  
Green Tea ◽  
Google Scholar ◽  
Blood Cholesterol ◽  
Antioxidant Compounds ◽  
Cholesterol Levels ◽  
Natural Remedies ◽  
Review Study ◽  
Tea Extract ◽  
Hypolipidemic Drugs

Abstract: Hypercholesterolemia, a condition when blood cholesterol levels exceed the normal value can lead to atherosclerosis and furthermore coronary heart disease. For that reason, some treatment actions are needed, one of which is by given hypolipidemic drugs. One of the natural remedies that act as hypolipidemic drugs is green tea. Green tea contains catechins, one of the antioxidant compounds. Catechins, especially epigallocatechin-3-gallate (EGCG), plays an important role in lowering blood cholesterol levels. The aims of this study is to determine the effect of antioxidants in green tea on blood cholesterol levels. This is a literature review study with data retrieved using 3 databases: Pubmed, ClinicalKey and Google Scholar. Using Green Tea OR Teh Hijau, Cholesterol OR Kolesterol, and Antioxidant OR Antioksidan as keywords and limiting the article searching based on inclusion and exclusion criteria, 12 studies was found to be reviewed. From 12 literature reviewed using experimental research methods with human and animal subjects with intervention green tea (extract, EGCG and PPE), all of them showed a significant reduction in blood cholesterol levels after the intervention with green tea. In conclusion, the antioxidants in green tea can reduce cholesterol levels in the blood.Keywords: antioxidant, green tea, EGCG, cholesterol, hypercholesterolemia  Abstrak: Kadar kolesterol yang melebihi batas normal atau biasa disebut hiperkolesterolemia dapat menyebabkan pembentukan aterosklerosis bahkan penyakit jantung koroner. Untuk itu diperlukan penanganan, salah satunya dengan pemberian obat hipolipidemia. Salah satu bahan alami yang dapat berperan sebagai hipolipidemia yaitu teh hijau. Teh hijau mengandung senyawa antiosidan yaitu katekin terutama epigallocatechin-3-gallate (EGCG) yang berperan penting dalam menurunkan kadar kolesterol dalam darah. Tujuan penelitian ini untuk mengetahui efek antioksidan pada teh hijau terhadap kadar kolesterol dalam darah. Penelitian ini berbentuk literature review dengan pencarian data menggunakan 3 database yaitu PubMed, ClinicalKey dan Google Scholar. Kata kunci yang digunakan yaitu Green Tea OR Teh Hijau, Cholesterol OR Kolesterol, dan Antioxidant OR Antioksidan. Setelah diseleksi berdasarkan kriteria inklusi dan eksklusi, didapatkan 12 literature yang di review. Dari 12 literature yang di review menggunakan metode penelitian eksperimental dengan subjek penelitian manusia dan hewan yang diberi teh hijau (ekstrak, EGCG dan PPE) semuanya menunjukkan hasil adanya penurunan kadar kolesterol darah yang signifikan setelah diberikan teh hijau. Sebagai simpulan, antioksidan pada teh hijau dapat menurunkan kadar kolesterol dalam darah.Kata Kunci: antioksidan, teh hijau, EGCG, kolesterol, hiperkolesterolemia

scholarly journals Kandungan Antioksidan Pada Daun Kelor (Moringa Oleifera) dan Potensi Sebagai Penurun Kadar Kolesterol Darah

2021 ◽  
Vol 9 (2) ◽  
Author(s):  
Angelyn Tjong ◽  
Youla A. Assa ◽  
Diana S. Purwanto
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Moringa Oleifera ◽  
Google Scholar ◽  
Blood Cholesterol ◽  
Exclusion Criteria ◽  
Traditional Medicines ◽  
Cholesterol Levels ◽  
Antioxidant Content ◽  
Moringa Oleifera Leaves

Abstract: One of the biggest risk factors for cardiovascular disease is hypercholesterolemia. Cholesterol is an important fat, however if it is excessive in the blood it can cause various diseases, one of which is cardiovascular disease. One of the traditional medicines used to reduce blood cholesterol levels is Moringa Oleifera leaves, which contain flavonoids and play an important role in lowering blood cholesterol levels. This study aimed to determine the antioxidant content of Moringa Oleifera leaves, the benefits of lowering blood cholesterol levels, and the dosage of administration. This study was conducted by using three databases, namely PubMed, ClinicalKey and Google Scholar to find articles which met the inclusion and exclusion criteria, then the assessment was carried out. There was a significant reduction in blood cholesterol levels when given Moringa leaves, as well as the dose given. In conclusion, antioxidants in Moringa leaves can reduce cholesterol levels in the blood.Keywords: antioxidants, moringa leaves, cholesterol, cardiovascular  Abstrak: Salah satu faktor risiko terbesar penyakit kardiovaskular adalah hiperkolesterolemia. Kolesterol merupakan lemak yang penting, namun jika berlebihan dalam darah dapat menyebabkan berbagai penyakit, salah satunya kardiovaskular. Salah satu obat tradisional yang digunakan untuk menurunkan kadar kolesterol darah adalah daun kelor (Moringa Oleifera), yang mengandung flavonoid dan berperan penting dalam menurunkan kadar kolesterol darah. Tujuan penelitian ini untuk mengetahui kandungan antioksidan daun kelor, manfaat sebagai penurun kadar kolesterol darah, dan dosis pemberian. Pencarian artikel menggunakan tiga database yaitu PubMed, ClinicalKey, dan Google Scholar untuk menemukan artikel sesuai dengan kriteria inklusi dan eksklusi, kemudian dilakukan penilaian. Terdapat penurunan kadar kolesterol darah yang signifikan ketika diberikan daun kelor dalam menurunkan kadar kolesterol darah, serta dosis yang diberikan. Sebagi simpulan, antioksidan pada daun kelor dapat menurunkan kadar kolesterol dalam darah. Kata Kunci: antioksidan, daun kelor, kolesterol, kardiovaskular

scholarly journals Efektivitas Terapi Murottal Al-Quran Terhadap Kecemasan Anak Dengan Leukemia “Literature Review”

2019 ◽  
Vol 4 (2) ◽  
pp. 109-114
Author(s):  
Ricky Zainuddin ◽  
Rahma La Maru
Keyword(s):  
Literature Review ◽  
Music Therapy ◽  
Auditory Nerve ◽  
Search Strategy ◽  
Final Analysis ◽  
Positive Influence ◽  
Post Intervention ◽  
Quantitative Evidence ◽  
Listening Process ◽  
The Brain

Background: Murottal therapy is a type of music therapy that has a positive influence on the listener, when someone listens to murottal therapy it will give stimulation to the eardrum then it will begin the listening process where every sound produced by the sound source will be passed through the auditory nerve to the auditory cortex in the brain. Then murottal therapy will work on the brain where when given a stimulus the brain will produce a decrease in cortisol so that it can provide feedback in the form of relaxed feeling and comfort. Methods: This research explores quantitative evidence published in pubmed electronic databases, google scholar. By using search strategy we found 73 articles with the potential of 10 studies included in the final analysis. Results: We found a significant post-intervention improvement in reducing anxiety for participants who received murottal Al-Qur’an therapy compared to all control grups. Conclusion: These results indicate that murottal Al-Qur'an therapy can be used as an alternative treatment to reduce anxiety of patients who experience anxiety disorders and nurses are expected to participate in this treatment training.

scholarly journals The Effectiveness of the Water Tepid Sponge to Decrease the Body Temperature in Children With Febrile Seizure

2020 ◽  
Vol 3 (2) ◽  
pp. 1
Author(s):  
Fera Faradilla ◽  
Rusli Abdullah
Keyword(s):  
Body Temperature ◽  
Literature Review ◽  
Febrile Seizure ◽  
Final Analysis ◽  
Febrile Seizures ◽  
Search Strategies ◽  
The Body ◽  
Google Scholar ◽  
Electronic Database ◽  
Quantitative Evidence

Abstract Background: Fever belongs to one of the triggers that resulted in febrile seizures. One of the actions of the non-pharmacological can be given to lower the body temperature in children with febrile seizure is the act of water tepid sponge. Purpose: this literature Review aims to analyze the effect of the adoption of the act water tepid sponge to decrease the body temperature in children who experienced febrile seizures. Methods: this Study explores quantitative evidence, published in electronic database such as Pubmed, Google Scholar, and Science Direct. With the use of search strategies, the researcher identified 39 articles that are potentially relevant to the purpose of the research, and 1 article included in the final analysis. Results: We can see a significant effect of decrease in body temperature in the group given the intervention water tepid sponge than a group of warm compresses. Conclusion: this Study shows that the actions of the water tepid sponge effective in lowering body temperature in children with febrile seizure. Keyword : Body temperature; Febrile seizures; Water tepid sponge.

scholarly journals The Use of Interpreters in Medical Education: A Narrative Literature Review

Societies ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 70
Author(s):  
Costas S. Constantinou ◽  
Andrew Timothy Ng ◽  
Chase Beverley Becker ◽  
Parmida Enayati Zadeh ◽  
Alexia Papageorgiou
Keyword(s):  
Medical Education ◽  
Literature Review ◽  
Search Strategy ◽  
Critical Assessment ◽  
Exclusion Criteria ◽  
Interpretive Approach ◽  
Assessment Skills ◽  
Narrative Literature ◽  
Research Questions ◽  
Narrative Literature Review

This paper presents the results of a narrative literature review on the use of interpreters in medical education. A careful search strategy was based on keywords and inclusion and exclusion criteria, and used the databases PubMed, Medline Ovid, Google Scholar, Scopus, CINAHL, and EBSCO. The search strategy resulted in 20 articles, which reflected the research aim and were reviewed on the basis of an interpretive approach. They were then critically appraised in accordance with the “critical assessment skills programme” guidelines. Results showed that the use of interpreters in medical education as part of the curriculum is scarce, but students have been trained in how to work with interpreters when interviewing patients to fully develop their skills. The study highlights the importance of integrating the use of interpreters in medical curricula, proposes a framework for achieving this, and suggests pertinent research questions for enriching cultural competence.

scholarly journals Evaluating the Connection between Thermal Comfort and Productivity in Buildings: A Systematic Literature Review

Buildings ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 244
Author(s):  
Ana Maria Bueno ◽  
Antonio Augusto de Paula Xavier ◽  
Evandro Eduardo Broday
Keyword(s):  
Literature Review ◽  
Thermal Comfort ◽  
Systematic Literature Review ◽  
Thermal Environment ◽  
Final Analysis ◽  
Personal Factors ◽  
Exclusion Criteria ◽  
Environment Variables ◽  
Main Factors ◽  
Combination Of Methods

The thermal environment is one of the main factors that influence thermal comfort and, consequently, the productivity of occupants inside buildings. Throughout the years, research has described the connection between thermal comfort and productivity. Mathematical models have been established in the attempt to predict changes in productivity according to thermal variations in the environment. Some of these models have failed for a number of reasons, including the understanding of the effect that several environment variables have had on performance. From this context, a systematic literature review was carried out with the aim of verifying the connection between thermal comfort and productivity and the combinations of different thermal and personal factors that can have an effect on productivity. A hundred and twenty-eight articles were found which show a connection between productivity and some thermal comfort variables. By means of specific inclusion and exclusion criteria, 60 articles were selected for a final analysis. The main conclusions found in this study were: (i) the vast majority of research uses subjective measures and/or a combination of methods to evaluate productivity; (ii) performance/productivity can be attained within an ampler temperature range; (iii) few studies present ways of calculating productivity.

Targeting the Cholesterol Paradigm in the Risk Reduction for Atherosclerotic Cardiovascular Disease: Does the Mechanism of Action of Pharmacotherapy Matter for Clinical Outcomes?

2021 ◽  
pp. 107424842110236
Author(s):  
Ruihai Zhou ◽  
George A. Stouffer ◽  
Sidney C. Smith
Keyword(s):  
Cardiovascular Disease ◽  
Clinical Outcomes ◽  
Mechanism Of Action ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Blood Cholesterol ◽  
Atherosclerotic Cardiovascular Disease ◽  
Pcsk9 Inhibitors ◽  
Cholesterol Lowering ◽  
Cholesterol Levels

Hypercholesterolemia is a well-established risk factor for atherosclerotic cardiovascular disease (ASCVD). Low-density lipoprotein cholesterol (LDL-C) has been labeled as “bad” cholesterol and high-density lipoprotein cholesterol (HDL-C) as “good” cholesterol. The prevailing hypothesis is that lowering blood cholesterol levels, especially LDL-C, reduces vascular deposition and retention of cholesterol or apolipoprotein B (apoB)-containing lipoproteins which are atherogenic. We review herein the clinical trial data on different pharmacological approaches to lowering blood cholesterol and propose that the mechanism of action of cholesterol lowering, as well as the amplitude of cholesterol reduction, are critically important in leading to improved clinical outcomes in ASCVD. The effects of bile acid sequestrants, fibrates, niacin, cholesteryl ester transfer protein (CETP) inhibitors, apolipoprotein A-I and HDL mimetics, apoB regulators, acyl coenzyme A: cholesterol acyltransferase (ACAT) inhibitors, cholesterol absorption inhibitors, statins, and proprotein convertase subtilisin kexin 9 (PCSK9) inhibitors, among other strategies are reviewed. Clinical evidence supports that different classes of cholesterol lowering or lipoprotein regulating approaches yielded variable effects on ASCVD outcomes, especially in cardiovascular and all-cause mortality. Statins are the most widely used cholesterol lowering agents and have the best proven cardiovascular event and survival benefits. Manipulating cholesterol levels by specific targeting of apoproteins or lipoproteins has not yielded clinical benefit. Understanding why lowering LDL-C by different approaches varies in clinical outcomes of ASCVD, especially in survival benefit, may shed further light on our evolving understanding of how cholesterol and its carrier lipoproteins are involved in ASCVD and aid in developing effective pharmacological strategies to improve the clinical outcomes of ASCVD.

scholarly journals Rapamycin: Drug Repurposing in SARS-CoV-2 Infection

2021 ◽  
Vol 14 (3) ◽  
pp. 217
Author(s):  
Jiri Patocka ◽  
Kamil Kuca ◽  
Patrik Oleksak ◽  
Eugenie Nepovimova ◽  
Martin Valis ◽  
...  
Keyword(s):  
Literature Review ◽  
Human Health ◽  
World Economy ◽  
Web Of Science ◽  
Drug Repurposing ◽  
Final Analysis ◽  
High Rate ◽  
Suitable Candidate ◽  
Promising Strategy ◽  
The World

Since December 2019, SARS-CoV-2 (COVID-19) has been a worldwide pandemic with enormous consequences for human health and the world economy. Remdesivir is the only drug in the world that has been approved for the treating of COVID-19. This drug, as well as vaccination, still has uncertain effectiveness. Drug repurposing could be a promising strategy how to find an appropriate molecule: rapamycin could be one of them. The authors performed a systematic literature review of available studies on the research describing rapamycin in association with COVID-19 infection. Only peer-reviewed English-written articles from the world’s acknowledged databases Web of Science, PubMed, Springer and Scopus were involved. Five articles were eventually included in the final analysis. The findings indicate that rapamycin seems to be a suitable candidate for drug repurposing. In addition, it may represent a better candidate for COVID-19 therapy than commonly tested antivirals. It is also likely that its efficiency will not be reduced by the high rate of viral RNA mutation.

scholarly journals Antibiotic Use at the End-of-Life in Patients with Advanced Dementia: A Systematic Literature Review

2020 ◽  
Vol 41 (S1) ◽  
pp. s120-s120
Author(s):  
Alexandre Marra ◽  
Mireia Puig-Asensio ◽  
Eli Perencevich
Keyword(s):  
Literature Review ◽  
Cohort Studies ◽  
End Of Life ◽  
Systematic Literature Review ◽  
End Of Life Care ◽  
Final Analysis ◽  
Antibiotic Use ◽  
Life Care ◽  
Advanced Dementia ◽  
Days Of Therapy

Background: Improving the use of antibiotics across the care continuum will be necessary as we strive to protect our patients from antimicrobial resistance. One potential target for antimicrobial stewardship is during end-of-life care of patients with advanced dementia. We aimed to perform a systematic literature review measuring the burden of antibiotic use during end-of-life care in patients with dementia. Methods: We searched PubMed, CINAHL, and Embase through July 2019 for studies with the following inclusion criteria in the initial analysis: (1) end-of-life patients (ie, dementia, cancer, organ failure, frailty or multi-morbidity); (2) antibiotic use in the end-of-life care; with the final analysis restricted to (3) patients with advanced dementia. Only randomized controlled trials (RCTs) and cohort studies were included. Results: Of the 93 full-text articles, 17 studies (18.3%) met the selection criteria for further analysis. Most of the included studies were retrospective (n = 8) or prospective (n = 8) cohort studies. These studies in combination included 2,501 patients with advanced dementia. Also, 5 studies (698 patients, [27.9%]) were restricted to patients with Alzheimer’s disease. In 5 studies in which data were available, fewer than one-quarter of patients (19.9%, 498) with advanced dementia were referred to palliative care. In 12 studies >50% of patients received antibiotics during the end-of-life period. Also, 15 studies did not report the duration of antimicrobial therapy. Only 2 studies reported the antimicrobial consumption in days of therapy per 1,000 resident days. Only 6 studies studied whether the use of antibiotics was associated with beneficial outcomes (survival or comfort), and none of them evaluated potential adverse effects associated with antibiotic use. Conclusions: There are significant gaps in the literature surrounding antimicrobial use at the end of life in patients with advanced dementia. Future studies are needed to evaluate the benefits and harms of using antibiotics for patients during end-of-life care in this patient population.Acknowledgement. We thank Jennifer Deberg from Hardin Library for the Health Sciences, University of Iowa Libraries on the search methods.Disclosures: NoneFunding: None

Alexithymia, fibromyalgia, and psychological distress among adolescents: literature review

2020 ◽  
Vol 32 (3) ◽  
Author(s):  
Eman Tariq Alslman ◽  
Shaher H. Hamaideh ◽  
Manar Ali Bani Hani ◽  
Huda Mohammad Atiyeh
Keyword(s):  
Psychological Distress ◽  
Literature Review ◽  
Theoretical Background ◽  
Mediating Effect ◽  
Google Scholar ◽  
The Relationship

AbstractThe purpose of this article is to review the literature regarding the relationships between alexithymia, fibromyalgia (FM), and psychological distress among adolescents. Google Scholar and databases were searched using alexithymia, fibromyalgia, psychological distress, and adolescent keywords. Studies that examine the relationship between alexithymia and fibromyalgia and the contribution of psychological distress on this relationship among adolescents are lacking. However, based on previous studies on adult samples and theoretical background, there are possible relationship between alexithymia and fibromyalgia as well as possible mediating effect of psychological distress on this relationship in adolescents. Further studies are recommended to examine the relationships between alexithymia, fibromyalgia, and psychological distress among adolescents.

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