scholarly journals RESEARCH OF RHEOLOGICAL PROPERTIES OF MEDICINAL SYRUP FOR ORAL USE

2020 ◽  
Vol 73 (4) ◽  
pp. 696-699
Author(s):  
Lena L. Davtian ◽  
Galyna P. Kukhtenko ◽  
Alona S. Voronkina ◽  
Viktoria V. Kudria

The aim of the present research was to investigate the rheological properties of the medicinal syrup for oral administration with glucosamine hydrochloride and levocarnitine. Matherials and methods: Coefficient of the dynamic flow (at shear rates of 3,49 and 10,3 s -1, as well as at shear rates of 27.2 and 149.0 s-1), mechanical stability, the index of destruction and restoration were studied. The rheological (structural-mechanical) properties of the samples were determined using a Rheolab QC rotary viscometer (AntonPaar, Austria) with coaxial cylinders CC27 / S-SN29766. The rheological parameters were studied at the temperature 20±0,5 °С. Results: It is established that the syrup has weakly expressed plastic viscous and thixotropic properties (the hysteresis area for the syrupis 1710.19 Pas/s). Such results characterize the system as a reopex. Conclusions: The results of the study enables classification of the research object as system with a low degree of fluidity. Such dependence is typical for systems of the Newtonian type of flow and characterizes the syrup under investigation as a weakly structured disperse system.

2013 ◽  
Vol 19 (No. 4) ◽  
pp. 148-153 ◽  
Author(s):  
P. Novotná ◽  
A. Landfeld ◽  
K. Kýhos ◽  
M. Houška ◽  
J. Strohalm

Fruit pulps contain fine particles of the flesh of the original fruit that are suspended in the fruit juice. This suspension has a tendency to settling or separation during measurements of its rheological properties in the rotational rheometer with coaxial cylinders (especially if the greater gap is used). In this case the use of a mixer is convenient. The mixer can serve as a tool for measurement of rheological properties and at the same time it can prevent the settling and it is not sensitive to the occurrence of greater particles in the measured fluid. The helical ribbon mixer was used in this work for measurement of five samples of fruit pulp. The mixer was calibrated by the use of Newtonian fluid of known viscosity (honey). The radius of the inner cylinder of hypothetical rotational rheometer was predicted from the assumption that mixer and cylinder exhibit the same torque necessary for the rotation at the same rotational speed. The average shear rate in the mixed pulp was predicted by using the relation valid for power law fluids and rheometer with coaxial cylinders. The radius (where the average shear rate was calculated) was chosen by the requirement that the shear rate would be almost independent of changes in the flow behaviour index valid for measured pulps. Firstly the flow behaviour index was predicted as a slope of torque vs. rotational speed dependence in log-log co-ordinates. It was found that the flow behaviour index varies in the range 0.2–0.3. The radius was predicted from a graph where shear rates for 0.2 and 0.3 are the same. Then the average shear rates were calculated from rotational speeds for individual flow behaviour indexes. Rheological properties measured by using a mixer correspond to those measured with a rotational rheometer with coaxial cylinders satisfactorily only in the case that the creeping flow regime was kept in the mixed fluid. The fruit pulps are strongly non-Newtonian fluids with very low values of the flow behaviour index around 0.2.


2009 ◽  
Vol 419-420 ◽  
pp. 53-56
Author(s):  
Bao Yu Song ◽  
Qing Xiang Yang ◽  
Feng Zhang ◽  
Dai Zhong Su

The apparent viscosity of aircraft grease with different nano-particles content, temperature and shear rates were studied using a rotational viscometer. The rheological properties of two types of aircraft grease, the basic grease and the one with nano-particles additives, were investigated using a rheometer. The results indicated that the apparent viscosity increases with the increase of nanoparticle concentration with the given ratio of nano-particles added. It was also found that the grease with and without the nano-particles both have yield stresses and clear shear-thinning properties. The shear-thinning phenomenon of the grease containing nano-particles is more evident than that of the basic grease. The experimental results also reveal that the rheological characteristics of both types of grease fall in Herschel-Bulkley class, and the nano-particles have a significant influence on the rheological parameters. At the end, the rheology mechanism was discussed based on the entanglement and orientation theories.


2021 ◽  
Vol 22 (4) ◽  
pp. 40-49
Author(s):  
A.N. Martekha ◽  
◽  
V.N. Andreev ◽  

Rheological properties are an important parameter for the quality of mayonnaise. This article in-vestigated the effect of adding olive oil on the rheological properties and color change of mayon-naise. The influence of the storage time of mayonnaise in the refrigerator on the change in rheo-logical properties was also investigated. Mayonnaise was prepared on a laboratory rotary disperser of the Turrex type with a rotor / stator system with a rotor speed range (10000-30000 rpm) at room temperature. Mayonnaise contains 75% oil with varying proportions of sunflower oil and ol-ive oil. Rheological measurements were carried out on a Brookfield rotary viscometer with con-centric cylinders at temperatures of 10 ° C and 25 ° C. Based on the data obtained, the consistency coefficient of the rheological parameters, the flow index and the apparent viscosity were calculat-ed. The color of the test samples of mayonnaise was measured using a three-color colorimeter. All mayonnaise samples exhibit non-Newtonian pseudoplastic flow with a defined thixotropic loop area. Research results have shown that the addition of olive oil affects the rheological properties and color of mayonnaise. The addition of olive oil to the oil phase of mayonnaise reduces shear stress, apparent viscosity, consistency factor and color change at 25 ° C and 10 ° C. When storing mayonnaise in the refrigerator for 15 days, the rheological parameters change. Sunflower oil may-onnaise (75%) has the highest value (L), which means it is measured instrumentally as the bright-est.


1964 ◽  
Vol 37 (2) ◽  
pp. 491-502
Author(s):  
F. E. Devine ◽  
J. A. Ross

Abstract The viscometer manufactured by A. Macklow-Smith Ltd., which operates at constant rate of extrusion, is a capillary instrument designed for the determination of flow properties of plastics. The instrument has been used for examining the rheological characteristics of rubber compounds and it has been possible to derive the shear stresses required to extrude material at various shear rates between 2 and 1050 sec−1. The general method of operation of the instrument for this purpose is discussed including the determination of preheat time before extrusion and the aspect of incipient vulcanization in the viscometer during extrusion. The effects of various lengths and diameters of dies on rheological parameters and entrance effects are discussed. An important aspect of the work is the observation of a piston height effect in the extruder barrel. Two different compounded polymers have been examined and in one case, the extrusion pressure was found to decrease with piston height whilst in the other highly elastic material, it was found that as the piston descended, the extrusion pressure increased to an equilibrium value. The importance of this effect in obtaining consistent shear stress data is discussed. Results of the work have been expressed in terms of apparent viscosity and also in terms of the parameters which describe a power law relating shear stress and shear rate within the capillary die. Rheological data have been obtained at various temperatures within the range of processing temperatures of the compounds. The effects on rheological properties of mastication and relaxation time after mastication have been examined. Results have been compared with figures obtained on conventional laboratory viscometers such as the Mooney Plastometer and the Wallace Rapid Plastimeter. A biconical, rotational viscometer has also been used at the lower range of shear rates and the results are compared with those obtained from the extrusion viscometer.


Author(s):  
Mariia Velia ◽  
Olena Ruban ◽  
Maryna Khalavka ◽  
Larisa Hohlova

The aim. To conduct the research on the choice of the basis for a mild drug with a semi-solid extract of feverfew for use in dermatology. Materials and methods. In the study of the solubility of a semi-solid extract of feverfew (SSFE) used the method of optical microscopy using a laboratory microscope “Konus Academy”. Determination of pH and homogeneity of the studied samples was performed according to the methods described in SPhU, Vol.1. The bioavailability of the model samples was investigated by diffusion in 3 % agar gel. Colloidal stability and thermal stability were determined according to the methods of GOST 29188.3-91. Measurements of rheological parameters were performed on a rotary viscometer “MYR 3000 V 2R” (Viskotech, Spain). Determination of particle distribution was performed using a laser diffraction analyzer of particle size Mastersizer 3000. Results. The best results in determining the organoleptic properties, stability and degree of release of biologically active substances (BAS) showed samples prepared on emulgel and gel bases. Structural and mechanical parameters of the samples on these bases proved the presence of a non-Newtonian type of flow with plastic and thixotropic properties. When determining the distribution of SSFE particles by optical diffraction, their smaller size was determined in the sample on an emulgel basis in comparison with the gel. Conclusions. Emulgel loaded with specific drugs has been found effective in some topical disorders, and it is emerging as potential drug delivery system in the area of dermatology. Since emu-lgel shows enhanced spreadability, adhesion, viscosity and extrusion. Based on the obtained results, an emulsion gel base was chosen as a carrier for a semi-solid drug with SSFE


Author(s):  
D. V. Efremov ◽  
◽  
I. A. Bannikova ◽  
Y. V. Bayandin ◽  
E. V. Krutikhin ◽  
...  

The work is devoted to the study of the rheological behavior of proppant carrier fluids used for hydraulic fracturing (HF) technology in order to increase oil recovery, including from hard-torecover oil and gas reserves, in a wide range of deformation rates using viscometers of various designs. Rheological properties were studied for proppant carrier fluids based on guar and Surfogel grade D, (type 70–100, produced by JSC “Polyex”) with comparable shear rate 128 s–1. Quasistatic experiments to determine the values of the dynamic viscosity of the liquids under study were carried out using a falling ball viscometer (according to the Stokes method). Using an original viscometer, consisting of two coaxial cylinders (rotary rheometer), the dynamic viscosity of surfogel was investigated in a wide range of shear rates. The viscoelastic properties of surfactants were studied using a Physica MCR501 rheometer, which has a plane-to-plane measuring system and allows rheological studies in rotational and oscillatory modes. A comparison of the rheological properties of fluids based on the guar and the viscoelastic surfactant is carried out and it is established that a fluid based on the viscoelastic surfactant has a higher dynamic viscosity and does not lose its elastic properties, which is an certain advantage over a fluid based on the guar.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jun Kameda ◽  
Hamada Yohei

AbstractSubmarine debris flows are mass movement processes on the seafloor, and are geohazards for seafloor infrastructure such as pipelines, communication cables, and submarine structures. Understanding the generation and run-out behavior of submarine debris flows is thus critical for assessing the risk of such geohazards. The rheological properties of seafloor sediments are governed by factors including sediment composition, grain size, water content, and physico-chemical conditions. In addition, extracellular polymeric substances (EPS) generated by microorganisms can affect rheological properties in natural systems. Here we show that a small quantity of EPS (~ 0.1 wt%) can potentially increase slope stability and decrease the mobility of submarine debris flows by increasing the internal cohesion of seafloor sediment. Our experiments demonstrated that the flow behavior of sediment suspensions mixed with an analogue material of EPS (xanthan gum) can be described by a Herschel–Bulkley model, with the rheological parameters being modified progressively, but not monotonously, with increasing EPS content. Numerical modeling of debris flows demonstrated that the run-out distance markedly decreases if even 0.1 wt% of EPS is added. The addition of EPS can also enhance the resistivity of sediment to fluidization triggered by cyclic loading, by means of formation of an EPS network that binds sediment particles. These findings suggest that the presence of EPS in natural environments reduces the likelihood of submarine geohazards.


Forests ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 417
Author(s):  
Xingcong Lv ◽  
Xiaolong Hao ◽  
Rongxian Ou ◽  
Tao Liu ◽  
Chuigen Guo ◽  
...  

The rheological properties of wood–plastic composites (WPCs) with different wood fiber contents were investigated using a rotational rheometer under low shear rates. The flow field information was analyzed and simulated by Ansys Polyflow software. The results showed that the WPCs with different wood fiber contents behaved as typical power-law fluids. A higher wood fiber content increased the shear thinning ability and pseudoplasticity of the WPCs. The pressure, velocity, shear rate, and viscosity distributions of the WPC during extrusion could be predicted by computational fluid dynamics (CFD) Ansys Polyflow software to explore the effects of different components on the flow field of WPCs.


2012 ◽  
Vol 174-177 ◽  
pp. 579-587
Author(s):  
Ting Shu He ◽  
Zhu Kai Li ◽  
Xiao Yan Huang

Fixed the composition of matrix slurry in low cement castable, added different additives such as STPP, KS-JS70, GLENIUX, Rheoplus, LMS-P, determined the slurry viscosity by using the NXS-11A rotary viscometer, analysised the rheological properties of the different matrix paste.Studies have shown that: there is a certain influence on the slurry rheology for different species and dosage, and there is the appropriate dosage. Analyzed the mechanisms of different admixtures on the rheological properties of slurry on theoretical.


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