scholarly journals Selected blood parameters altered by different doses of pesticide Malathion in albino rat (Rattus-norvegicus)

2020 ◽  
Vol 21 (3) ◽  
pp. 93-103
Author(s):  
C.D. Sharma ◽  
Neha Shukla ◽  
Geeta Bansal
Keyword(s):  
Body Weight ◽  
Hematological Parameters ◽  
Blood Parameters ◽  
Control Agent ◽  
The Body ◽  
Hematological Parameter ◽  
Albino Rats ◽  
Albino Rat ◽  
Toxicological Effects ◽  
Different Doses

Organophosphate pesticides Malathion used as pest control agent in agriculture, household, kitchen and other places. Malathion is found in market with different trade names. It is used with its action properties against various insects and pest. It is used with the largest group of poisonous substances that are widely broadcast today. Present study is based on the effects of different doses of Malathion on routine hematological parameters like RBCs, WBCs, Hb%, CT, PT, ESR, PCV, MCV, MCH, and MCHC. Four doses were selected according to the body weight of albino rats. The doses were selected as four types on the basis of per kilogram body weight of albino rat. They were 25, 50, 75,100 mg per Kg body weight for 7 and 15 days of treatment.The findings indicate that the above parameter fluctuates significantly as amount of dose increases. Hematological parameter indicates that the total body of the animals gets affected by the Malathion. It causes various other toxicological effects on the body of albino rats. There was a combined study of male and female albino rats.

Effect of Clomiphene Citrate and Letrozole on Body Weight of female Albino Rat for Consecutive 1-4 Estrous Cycles

2021 ◽  
Vol 15 (11) ◽  
pp. 2938-2941
Author(s):  
Fauzia Qureshi ◽  
Syeda Rizwana Jafri ◽  
Hafiza Sadia Ahmad ◽  
Uzma Waseem ◽  
Ursula Akif ◽  
...  
Keyword(s):  
Body Weight ◽  
Estrous Cycle ◽  
Ovulation Induction ◽  
Clomiphene Citrate ◽  
The Body ◽  
Control Group ◽  
Albino Rats ◽  
Albino Rat ◽  
Estrous Cycles ◽  
Experimental Group

Background: Ovulation induction with clomiphene citrate in women with infertility has been practiced more than 40% years but in infertile patients this treatment plan proved to be ineffective with multiple complication. Body weight plays an important role modulating reproductive development and functioning. Aim: To observe the effects on body weight of female albino rat after use of clomiphene citrate and letrozole for consecutive 1-4 estrous cycles Method: Eighty four adult female Albino rats were equally divided into three groups for this research. Body weight of each rat was measured before and after the experiment. Vaginal smear cytology of each rat was performed to study different phases of estrous cycle. Control group A was given normal saline orally , In Experimental group B rats were given letrozole (Femara) at dose 5mg/kg orally and in Experimental group C rats were given clomiphene citrate at dose 100ug/kg orally. Results: Significant weight gain is observed in rats taking clomiphene citrate as compared to letrozole Conclusion : Comiphene citrate directly affects the body weight which indirectly reduces the ovulation induction and pregnancy rate. Letrozole is good alternate for ovulation induction and for CC resistant patients. Keywords: Estrous cycle, body weight, citrate and letrozole

scholarly journals ORGAN WORK AND ORGAN WEIGHT

1939 ◽  
Vol 69 (3) ◽  
pp. 467-483 ◽  
Author(s):  
Florence Walter ◽  
T. Addis
Keyword(s):  
Body Weight ◽  
Organ Weight ◽  
The Body ◽  
Heart Weight ◽  
Albino Rats ◽  
Liver Protein ◽  
Kidney Weight ◽  
Albino Rat ◽  
Liver Size ◽  
Rate Of Growth

1. The ratios between the rates of growth of the body and of the heart, kidneys, and liver are approximately uniform between 40 gm. body weight and the body weight at maturity in the albino rat. The male and female hearts grow at 0.75 times the rate of growth of the body, the male kidneys at 0.717 times, the female kidneys at 0.648 times, and the liver at 0.838 times the rate of growth of the body as a whole. 2. Formulas for the prediction of organ weight from body weight were derived from the data on 1591 albino rats kept under constant conditions. 3. A series of experiments in which dietetic and metabolic variables were introduced into otherwise constant conditions showed that the heart weight was not affected by diet, and that both kidney weight and weight of liver protein (used as a measure of effective liver size) varied in the direction of change in the protein content of the diet. Decrease in rate of metabolism induced by thyroidectomy and increase in metabolism following the administration of thyroxin led to a corresponding fall and rise of heart, kidney, and liver protein weight. These results were confirmed in experiments on fasted rats with the exception that under these conditions thyroidectomy did not appreciably decrease liver protein weight relatively to fasted controls. Increase in organ metabolism due to dinitrophenol had no effect on organ weight. 4. When experimental changes alter the composition of the body with respect to fat or water, the comparison of experimental and control organ weights in terms of any one function of body weight is fallacious. 5. Conditions that change kidney weight usually change liver protein weight in the same direction and roughly to the same degree. The possible meaning of two exceptions to this rule is discussed. 6. The observations made are regarded as supporting the hypothesis that, after weaning, change in the weight of the heart, kidney, and liver protein is determined mainly by change in the amount of work done by these organs.

scholarly journals Potential role of probiotic species in ameliorating oxidative stress, effect on liver profile and hormones in male albino rat model

2021 ◽  
Vol 19 ◽  
pp. 205873922110161
Author(s):  
Haseeb Anwar ◽  
Ghulam Hussain ◽  
Azhar Rasul ◽  
Syed Muhammad Ali Shah ◽  
Syed Ali Raza Naqvi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Liver Enzymes ◽  
Strong Support ◽  
Blood Parameters ◽  
The Body ◽  
Male Rats ◽  
Albino Rats ◽  
Stress Effect ◽  
Indigenous Species ◽  
Albino Rat

Probiotics are living micro-organism preparations which can vigorously inhibit the probable pathogens colonization in the gut microbial ecology. Current experiment was designed to investigate the efficacy of imported probiotic species compared with the indigenous probiotics species on the oxidative stress, enzymes, and hormones in animal model. Thirty Albino rats were equally divided into three groups with 10 rats ( n = 10) in each group as Control (C), supplemented with imported probiotic species (IP), and supplemented with indigenous probiotics species (InP) for 21 days under controlled environment. The evaluation of treatments was done by testing the serum oxidative stress markers, liver enzymes (Aspartate transaminase and Alanine aminotransferase), lipid profile, and hormonal dynamics including Lutinizing hormone (LH), follicular stimulating hormone (FSH), and growth hormone (GH) in albino male rats. Results revealed that use of indigenous probiotic species significantly ( p < 0.05) reduces the oxidative stress and improves the antioxidant capacity; liver enzymes, total cholesterol, and LDL-Cholesterol were also reduced significantly ( p < 0.05) in InP as compared to IP group. Moreover, results of hormones including LH, FSH, and GH explored that indigenous probiotics have significant ( p < 0.05) potential to improve these hormones as compared to imported probiotics. Although, it could be concluded that InP have beneficial role in preventing the body from oxidative stress as well as in improving the blood parameters but comprehensive studies are required to investigate the detail gut ecology of the indigenous species which will definitely a strong support in preparing a more suitable local probiotic supplement.

scholarly journals Effect of COMBOzyme® and Renasol AD3E® on Body Weight and Hematological Parameters in Broiler Chicken

2013 ◽  
Vol 22 (1-2) ◽  
pp. 97-103
Author(s):  
A Mustari ◽  
S Rana ◽  
MM Rahman
Keyword(s):  
Body Weight ◽  
Broiler Chickens ◽  
Hematological Parameters ◽  
Research Work ◽  
The Body ◽  
Hematological Parameter ◽  
Control Group ◽  
Group A ◽  
Group B ◽  
Hb Concentration

The present research work was undertaken to study the effect of multi enzymes and vitamin AD3E on body weight and hematological parameter (TEC, Hb Concentration and ESR) in growing broilers fed with enzyme and vitamin AD3E with normal broiler ration. 20 broiler chickens of 10 (ten) days old “Hubbard Classic” were taken for study. The chicks were divided randomly into four groups with five chicks in each group. Group A designated as control group and was given normal broiler ration and rest of the groups were given enzyme and vitamin preparation. Group B was given enzyme only, group C was given vitamin only and group D was given both enzyme and vitamin as per schedule. It was observed that enzyme and vitamin AD3E preparation enhanced the growth rate of broilers. On the final day of experiment the body weight was significantly increased (P<0.01) in the treated groups in comparison to that of control group, TEC, Hb concentration and ESR values were significantly (P<0.01) increased in all treated  groups than the control group and among the treated groups vitamin AD3E showed lowest performance.DOI: http://dx.doi.org/10.3329/pa.v22i1-2.16471 Progress. Agric. 22(1 & 2): 97-103, 2011 

Significance of graded doses of aqueous seed extract of Moringa oleifera (L) on live body weight, gonadal, extragonadal dimensions and sperm reserves of Yankasa rams

2021 ◽  
pp. 33-40
Keyword(s):  
Body Weight ◽  
Moringa Oleifera ◽  
Seed Extract ◽  
The Body ◽  
Control Group ◽  
Live Body Weight ◽  
And Control ◽  
Standard Techniques ◽  
Different Doses ◽  
Apparently Healthy

The aim of the study was to investigate the effects of Moringa oleifera aqueous seed extract on live body weight, gonadal and extragonadal dimensions and sperm reserves of Yankasa rams. Twenty five apparently healthy Yankasa rams aged 1-2 years and weighing 19.0 ± 2.1 Kg were used for the study. The rams were randomly selected into five groups: A, B, C, D and E with five rams in each group as treatment and control groups respectively. Groups A - D were given oral dose of Moringa oleifera aqueous seed extract at a dose rate of 1000, 2000, 3000, 4000 (mg/kg), respectively while group E was given 10 ml/kg water orally, daily for five months. Live body weight, gonadal and extragonadal reserves were determined according to standard techniques. The results showed a significant increase in live body weight in the months of April to June among rams treated with different doses of Moringa oleifera aqueous seed extract compared with the control group. The control group showed no significant differences in the body weight, gonadal and extragonadal dimensions and sperm reserves. In conclusion, the treatment of Yankasa rams with Moringa oleifera aqueous seed extract increased live body weight, but had no significant effects on gonadal and extragonadal dimensions and sperm reserves in Yankasa rams. Therefore, it is recommended that M. oleifera aqueous seed extract can be used at doses of 2000mg/kg to 3000mg/kg in Yankasa rams for optimum gain in live body weight.

scholarly journals The Effects of Different Exercise Types on Hematological Parameters in Sedentary Women

2018 ◽  
Vol 6 (8) ◽  
pp. 96 ◽  
Author(s):  
Güner Çiçek
Keyword(s):  
Heart Rate ◽  
Body Weight ◽  
Blood Cell ◽  
Aerobic Exercise ◽  
Hematological Parameters ◽  
Exercise Group ◽  
The Body ◽  
Strength Exercise ◽  
Strength Exercises ◽  
Sedentary Women

The purpose of this study is to investigate the effect of aerobic and strength exercises on hematological parameters in sedentary women. To achieve the purpose of this study, a total of 23 volunteers including aerobic exercise group (AE, n: 10), strength exercise group (SE, n:13) were selected as participants. Two different exercises were applied for 4 days a week, throughout 16 weeks, within 60 minutes for each exercise with the intensity of heart rate (HR) 60-70 percent. The HR was measured using a heart rate monitor for each subject.The women's white blood cell (WBC), thrombocyte (PLT), red blood cell (RBC), hemoglobin (HGB), hematocrit (HCT) and mean corpuscular volume (MCV) were measured before and after exercise. For statistical analysis, the Wilcoxon signed-rank test was used for intra-group evaluations, and the Mann Whitney U test was used for inter-group evaluations. After the exercise program, there were a meaningful decrease in the body weight and body mass index (BMI) the women in both intervention groups. In addition, in the hematological results of strength exercise group, some meaningful decreases were determined in the values of RBC, HGB, HCT and MCV (p<0.01). As a results, it was observed that regular aerobic and strength exercises can positively influence the body weight and BMI parameters of sedentary women. Along with this, a meaningful decrease has been found in the values of RBC, HGB, HCT and MCV of strength exercise group compared to aerobic exercise.

scholarly journals The effect of Ricinus communis seeds extract on reproductive activity and blood values of male rabbits

2019 ◽  
Vol 12 (1) ◽  
pp. 97-106
Author(s):  
AL-Khafaji Nazar
Keyword(s):  
Estrogenic Activity ◽  
Ricinus Communis ◽  
Hematological Parameters ◽  
Abdominal Cavity ◽  
Hemoglobin Concentration ◽  
Reproductive Activity ◽  
Treated Group ◽  
Blood Parameters ◽  
The Body ◽  
Tropical Regions

Ricinus communis L. of Euphorbiaceae family is a widespread plant in tropical regions. It is used in traditional medicines as an anti- fertility agent in India and different parts of the world. The ether soluble portion of the methanol extract of R. communis var minor possesses anti-implantation, anti - conceptive and estrogenic activity in rats and mice when administered subcutaneously.The study was conducted on 10 local breed male rabbits, 1-2 years old, of 1-2 kg body weight. The animals were divided into two groups, control non – treated group and treated group in which animals were treated with single daily dose of 50 mg /kg b. wt. P.O. of decorticated and defatted castor seeds (DDCS) for 14 days. 28th day post treatment, animals were anesthetized by diethyl ether, sacrificed, abdominal cavity was open. The sexual organ (testes, epididymis, prostate and seminal vesical) weighed. In addition to take a biopsy from each one for histopathological changes. The study also included clinical and hematological parameters, in addition to sperm counts and the changes in sperm morphology.Body weight, body temperature increased significantly in treated males. While in non- treated group there were no significant changes. Respiratory rates and heart rate were none significantly changed in treated and non- treated males.Bleeding time none significantly increased in treated males, but increased significantly in none treated males. Clotting times decreased none significantly in treated and non- treated males. The blood parameters including, total erythrocytes count, hemoglobin concentration, PCV% , MCV, MCH, MCHC, total leucocyte and differential leucocyte counts were either increased or decreased none significantly in both groups. The results revealed that the effects of exposure to extract of ricin for 14 days on reproductive efficiency of rabbits, exhibited Significant decrease in weights of testes, epididymis, tails, heads of epididymis, seminal vesicles and prostate in treated males in comparison with those of non- treated males. While the body of epididymis did not show a significant changes.Significant decrease in live sperm numbers, number of sperms in epididymal head, in addition to deformities in high numbers of sperm, including enlarged or small sperms. breaks head, and its detachment, presence of two heads in one sperm, bifurcation of tail and its breaking, sperm coiling in samples from treated males in comparison with those from non-treated males.Histological changes were hyperplasia of lining epithelial cells and vacuolar degenerative changes, loss of spermatogenesis, and spermatocytes necrosis in those from treated males.

scholarly journals Preliminary Phytochemical Analysis of Aqueous Extract of Leaf Psidium guajava and Its Effect on Some Haematological Parameters

2021 ◽  
pp. 16-24
Author(s):  
M. I. Uneze ◽  
D. N. Azionu
Keyword(s):  
Body Weight ◽  
Aqueous Extract ◽  
Hematological Parameters ◽  
Research Work ◽  
Psidium Guajava ◽  
Albino Rats ◽  
Phytochemical Analysis ◽  
Standard Procedures ◽  
Dose Dependent ◽  
Average Body

Various parts of psidium guajava linn are used in ethnomedicine in controls and treatments of different disorders such as liver, heart, and blood related disorders [11]. This research work investigate qualitative phytochemical composition of ethanol leaf extract of psidium guajava linn and its effect on some hematological parameters in albino rats. Qualitative phytochemical analysis of the extract was performed by standard procedures. A total of 20 adult male albino rats were used, they were randomly placed into 5 groups (A, B, C, D and E) each group containing 4 rats groups A, B, C, and D were administered, via oral intubation, the extract at doses of 200, 400, 600, and 800 mg/kg body weight respectively of the extract for 7 consecutive days. Phytochemical screening shows that the extract was rich in tannins anthraquinones, and flavonoid while alkaloids, saponins, terpenes and glycoside were slightly present. There was a decrease in the average body weight, physical activities, and feed and water intake of the rats in the test groups relative to the control hemoglobin concentrate, total white blood cell and packed cell volume recorded in the groups  administered the extract were significantly (p<0.05) higher than in the control this effect on  the haemotological parameters was found to be dose dependent. The findings of this study suggest that the aqueous extract of the fruit plants may be useful in control and treatment of blood related disorders.  These useful applications may be as a result of the phytochemical present in the extract.

scholarly journals Effects of Imidacloprid-Contaminated Feed Exposure on Hematological Parameters in Adult Rabbits (Oryctolagus Cuniculus)

2020 ◽  
Vol 7 (3) ◽  
pp. 439-444
Author(s):  
Md Alamgir Kobir ◽  
Latifa Akther ◽  
Imam Hasan ◽  
Md Ahosanul Haque Shahid ◽  
Ziaul Haque ◽  
...  
Keyword(s):  
Leukocyte Count ◽  
Hematological Parameters ◽  
Blood Parameters ◽  
The Body ◽  
Standard Diet ◽  
Cell Analysis ◽  
Differential Leukocyte Count ◽  
Once Daily ◽  
Important Index ◽  
Fresh Vegetables

Blood parameters are an important index to assess the body homeostasis in mammals. Here, the effect of pesticide (imidacloprid) contaminated feed exposure on the haematological parameters of adult rabbits (n=15) was studied. Pesticides (Imidacloprid, Bildor® 0.5ml (100mg)/L water spray on vegetables and green grass) exposed feed fed to rabbits with wash (washed feed rabbit) or without a wash (not washed feed rabbit) in the once-daily morning for every alternative day up to 15 days. Control rabbits have received a standard diet (fresh vegetables and green grass). The blood cell analysis showed that the total erythrocyte count, packed cell volume, and haemoglobin values were not changed significantly in pesticide exposed rabbit. For differential leukocyte count, the percentage of neutrophil and eosinophil was significantly decreased in the pesticide-exposed rabbit as compared to the control rabbit. The lymphocyte percentage was increased significantly in pesticide-exposed rabbits compared to control rabbits. Interestingly, the number of lymphocytes was significantly increased in not washed feed rabbits compared to wash feed rabbits. The results of the present study suggest that residue of agriculturally used pesticides may affect the body homeostasis of animals. Res. Agric., Livest. Fish.7(3): 439-444,  December 2020

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