scholarly journals The Effects of Different Exercise Types on Hematological Parameters in Sedentary Women

2018 ◽  
Vol 6 (8) ◽  
pp. 96 ◽  
Author(s):  
Güner Çiçek
Keyword(s):  
Heart Rate ◽  
Body Weight ◽  
Blood Cell ◽  
Aerobic Exercise ◽  
Hematological Parameters ◽  
Exercise Group ◽  
The Body ◽  
Strength Exercise ◽  
Strength Exercises ◽  
Sedentary Women

The purpose of this study is to investigate the effect of aerobic and strength exercises on hematological parameters in sedentary women. To achieve the purpose of this study, a total of 23 volunteers including aerobic exercise group (AE, n: 10), strength exercise group (SE, n:13) were selected as participants. Two different exercises were applied for 4 days a week, throughout 16 weeks, within 60 minutes for each exercise with the intensity of heart rate (HR) 60-70 percent. The HR was measured using a heart rate monitor for each subject.The women's white blood cell (WBC), thrombocyte (PLT), red blood cell (RBC), hemoglobin (HGB), hematocrit (HCT) and mean corpuscular volume (MCV) were measured before and after exercise. For statistical analysis, the Wilcoxon signed-rank test was used for intra-group evaluations, and the Mann Whitney U test was used for inter-group evaluations. After the exercise program, there were a meaningful decrease in the body weight and body mass index (BMI) the women in both intervention groups. In addition, in the hematological results of strength exercise group, some meaningful decreases were determined in the values of RBC, HGB, HCT and MCV (p<0.01). As a results, it was observed that regular aerobic and strength exercises can positively influence the body weight and BMI parameters of sedentary women. Along with this, a meaningful decrease has been found in the values of RBC, HGB, HCT and MCV of strength exercise group compared to aerobic exercise.

scholarly journals PO-148 Effect of Aerobic Exercise on the Expression of CaMKIIδ/MEF2 in Hypertensive and Physiological Cardiac Hypertrophy

2018 ◽  
Vol 1 (4) ◽  
Author(s):  
Man Zhu ◽  
Lijun Shi
Keyword(s):  
Body Weight ◽  
Cardiac Hypertrophy ◽  
Aerobic Exercise ◽  
Weight Ratio ◽  
Exercise Group ◽  
The Body ◽  
Expression Level ◽  
Heart Weight ◽  
Control Group ◽  
Body Weight Ratio

Objective The type II calcium/calmodulin-dependent protein kinase IIδ (CaMKIIδ) signal plays a key role in the development of cardiac hypertrophy. This study used CaMKIIδ as an entry point to investigate the mechanism of moderate-intensity aerobic exercise affecting myocardial function. Methods Male spontaneously hypertensive rats (SHRs) and Wistar-Kyoto rats (WKYs), 12 weeks age, were randomly divided into aerobic exercise group (SHR-EX/WKY-EX) and sedentary control group (SHR-SED/WKY-SED), with 12 rats in each group. The aerobic exercise group conducted an 8-week treadmill exercise training with a slope of 0°, 20m/min (about 55-65% of maximal aerobic velocity), 60min/day, and 5d/wk. The control group did not exercise. The body weight of each group of rats was measured weekly and the blood pressure of the rats was measured non-invasively. After 8 weeks, the hearts of SHR-EX group, WKY-EX group, SHR-SED group and WKY-SED group were weighed, and then myocardial tissue sections were taken for HE staining to observe the thickness of the ventricular wall and the morphology of myocardial cells. The expression of CaMKIIδ and MEF2 in each group was determined by Western blotting. Results (1) The body weight of SHR-SED group was significantly higher than that of SHR-EX group (p<0.01), and the heart weight of rats in exercise group changed significantly. The WKY-EX group had greater heart weight than the WKY-SED group, and the SHR-SED group was heavier than the SHR-EX group (p<0.05). The heart weight/body weight ratio of the WKY-EX group was significantly higher than that of the WKY-SED group (p<0.01). The heart weight/body weight ratio of SHR-EX group and SHR-SED group was higher than that of WKY-EX group and WKY-SED group (p<0.01). (2) Compared with the WKY-SED group, the SHR-SED group had loose interstitial cells and increased single cell area. The SHR-EX group is more compact than the SHR-SED group, and the cell cross-sectional area is reduced. (3) The expression of CaMKIIδ protein in SHR-EX group was significantly lower than that in SHR-SED group (p<0.01), but the expression level of CaMKIIδ in WKY-EX group was significantly higher than that in WKY-SED group (p<0.01). The expression level of CaMKIIδ was significantly higher in the SHR-SED group than in the WKY-SED group. In addition, the expression of MEF2 protein in SHR-EX group and WKY-SED group was significantly lower than that in SHR-SED group (p<0.01), while the MEF2 expression level in WKY-EX group was higher than WKY-SED group and SHR-EX group (p<0.05). Conclusions There is an interaction between aerobic exercise and hypertension. Aerobic exercise can effectively delay the development of hypertensive cardiac hypertrophy by regulating the expression of CaMKIIδ and MEF2 protein in the myocardium, but it can also cause cardiac hypertrophy in normal heart. It is one of the important mechanisms affecting the myocardial morphology and function.    

The Predictive Role of Biochemical Plasma Factors in Patients with Severe Traumatic Brain Injuries

2019 ◽  
Vol 70 (5) ◽  
pp. 1754-1757
Author(s):  
Marius Toma Papacocea ◽  
Ioana Anca Badarau ◽  
Mugurel Radoi ◽  
Ioana Raluca Papacocea
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Blood Cell ◽  
Brain Injuries ◽  
Hematological Parameters ◽  
Group Versus ◽  
Public Health Problem ◽  
Traumatic Brain Injuries ◽  
High Rate ◽  
Control Group

Traumatic brain injuries (TBI) represent a high impact public health problem due to a high rate of death , long term disability and occurrence especially in young adults. Despite several promising animal studies, several parameters were proposed as biological markers and were assessed for this aim. Our study proposes the study of the early biochemical changes in association to hematological parameters for severe TBI patients prognosis. 43 patients with acute TBI were included in study based on clinical, laboratory and imagistic findings. The severity of the TBI was established by Glasgow Coma Scale GCS 3-8. In all patients were evaluated hematologic parameters (Red blood cell count - RBC, Hematocrit, blood Hemoglobin, White blood cell - WBC, Platelet count and biochemical parameters (glucose, urea, creatinine, electrolytes). Outcome was expressed as Glasgow Outcome Scale (GOS), between 1-5. Values were compared to control group -15 cases. Significant early differences in body temperature, heart rate, and systolic blood pressure were observed in TBI group versus control (p[0.05). After correlation, laboratory findings significantly associated to severe outcome - GOS = 1, 2 - (p[0.05) were plasma Na decrease and significant glucose increase. An early increase of temperature and decrease of Na may predict a severe outcome in patients with acute TBI; association with shifts in heart rate and blood pressure, imposes aggressive treatment measures.

scholarly journals Biochemical and Hematological Effect of Cordyla pinnata Following Acute and Sub-Acute Exposure to Rattus norvegicus

2020 ◽  
Vol 14 (1) ◽  
pp. 43-50
Author(s):  
Adenike R. Alawode ◽  
◽  
Muhammed Dauda ◽  
Adeyemi Gbolagade Adegbola ◽  
Olabode Richard Babatunde ◽  
...  
Keyword(s):  
Body Weight ◽  
Blood Cell ◽  
Methanol Extract ◽  
Hematological Parameters ◽  
Clinical Signs ◽  
Weight Ratio ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Significant Treatment

Background: Cordyla pinnata (C. pinnata) is commonly used in traditional medicine for the treatment of various ailments. The aim of this study was to assess the toxic and safety potentials of the methanol extract of C. pinnata in rats.  Methods: The methanol extract of C. pinnata was administered to the rats orally once daily at a dose of 0, 150, 300 or 600 mg/kg, body weight for 21 days. The toxicity was assessed using mortality rate, clinical signs, body and organ weights, hematological and serum chemistry indices. Results: The extract at 150, 300 or 600 mg/kg significantly decreased (p<0.05) the serum alanine aminotransferase and sodium, but increased the urea concentration compared with those in the controls. There were no significant treatment-related alterations in the activities of aspartate aminotransferase, albumin, bilirubin, total proteins, chloride and creatinine. Also, the serum hematological parameters including Hemoglobin (HB), Packed Cell Volume (PCV), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentrations (MCHC) and Red Blood Cell (RBC) did not change significantly (p<0.05). However, there were significant increases (p<0.05) in White Blood Cell (WBC) and platelet counts, in weight gain and relative liver, kidney, lung and heart body weight ratio in the rats treated with 600 mg/kg of the extract compared with those in the controls.  Conclusion: The C. pinnata extract was safe and non-toxic to the rats’ liver and blood components at doses up to 600 mg/kg for a period of 21 days. However, alterations found in the markers of kidneys integrity call for exercising caution when using this extract orally as a long-term remedy.

scholarly journals Anti-arthritic Evaluation of Different Extracts of Boerhaavia diffusa Linn. in FCA Induced Arthritis In Rats

2018 ◽  
Vol 8 (5-s) ◽  
pp. 388-393 ◽  
Author(s):  
Deepika Parmar ◽  
Neetesh Kumar Jain ◽  
Vivek Tomar
Keyword(s):  
Body Weight ◽  
Phenolic Compounds ◽  
Methanolic Extract ◽  
Hematological Parameters ◽  
Extraction Methods ◽  
The Body ◽  
Haematological Parameters ◽  
Phytochemical Study ◽  
Methanolic Extracts ◽  
Boerhaavia Diffusa

The main aim of study is to evaluate the anti-arthritic effect of different extracts of Boerhaavia diffusa in arthritic rats. Different extracts were prepared by successive solvent extraction methods by using the various polar and non polar solvents and their % yields were calculated. Arthritis was induced by FCA induced arthritis model in rats and paw volume was measured on different days. Body weights of all animals were also measured simultaneously and at the end of experiment some haematological parameters were measured. On preliminary phytochemical studies extracts showed the presence of alkaloids, fatty acids, terpenoids, flavonoids and phenolic compounds. Among all extracts, methanolic extract significantly decreased the paw volume in all treated groups. Methanolic extracts also restored the body weight significantly. The results of our study revealed that all the extracts treated group’s causes significant alterations in the hematological parameters and maximal effects were observed at 400 mg/kg. Since methanolic extract showed best activity in arthritic model and its phytochemical study showed presence of flavonoids and phenolic compounds, so it may be possible that anti-arthritic activity of root extracts may be due to presence flavonoids.  Keywords: Arthritis, FCA induced arthritis, Boerhaavia diffusa, haematological parameters, and Body weight

Acute and sub-chronic toxicity of the aqueous extract of Ficus vogelii (Miq.) Miq. stem bark in rats

2021 ◽  
Vol 10 (2) ◽  
pp. 89-97
Author(s):  
EL Lappa ◽  
◽  
C Bogning Zangueu ◽  
EL Nguemfo ◽  
JJ Kojom Wanche ◽  
...  
Keyword(s):  
Body Weight ◽  
Aqueous Extract ◽  
Chronic Toxicity ◽  
Hematological Parameters ◽  
Lethal Dose ◽  
Relative Weight ◽  
Stem Bark ◽  
The Body ◽  
Female Rats ◽  
Male Rats

Ficus vogelii is a medicinal plant mainly found in tropical Africa and reported to treat inflammatory complaints. This study aims to evaluate the acute and sub-chronic toxicity of the aqueous extract of Ficus vogelii stem bark in wistar rats. For acute study, aqueous extract at a single dose of 5000 mg/kg body weight was administered to female rats and observed for 14 days. In the sub-chronic study, the extract was administered daily to both sex rats at the doses of 100, 200, 400, and 600 mg/kg body weight for 28 consecutive days. Body weight was measured weekly, while hematological, biochemical, and histopathological parameters were analyzed after euthanize. Aqueous extract of Ficus vogelii at all tested doses didn’t produced any mortality or significant change on the body weight and relative weight of rats on acute and sub-chronic studies. The lethal dose 50 was estimated greater than 5000 mg/kg (DL50˃5000 mg/kg). Hematological parameters were recorded non-significant in all treated rats. Aqueous extract at 600 mg/kg significantly changed transaminases and alkaline phosphatase activities, these changes were reversible in satellites. The concentrations of bilirubin was increased at 200 and 600 mg/kg in male rats, at 100, 400 mg/kg in female rats. The levels of lipids markers didn’t changed, except the significant decrease of LDL-cholesterol. Histological examination didn’t showed any change in the architecture of the liver and kidney of rats treated compared to control. Thus aqueous extract of Ficus vogelii stem bark didn’t produced adverse effects in rats after oral acute and sub-chronic treatment.

scholarly journals The Clinical and Hematological changes in Rabbits exposed to Melia azedarach fruits under experimental conditions

2015 ◽  
Vol 1 (1) ◽  
pp. 12 ◽  
Author(s):  
AL- Zubaedi Raad Mahmood
Keyword(s):  
Body Weight ◽  
Body Temperature ◽  
Bleeding Time ◽  
Hematological Parameters ◽  
The Body ◽  
Melia Azedarach ◽  
Control Group ◽  
Clotting Time ◽  
Experimental Conditions ◽  
Hb Concentration

The study was conducted on 10 local breed rabbits, of 1-2 years age, of 1- 1.5 kg body weight. They were feed concentrated and green food, and left ad libitum for water, and kept in room of 20- 25 oC. The animals divided into two groups of 5 each. First as treated group received the plant in powder form mixed with the food at a dose rate of 5 g/ animal / day for three weeks , while the second left without exposure as a control group .The main dependent parameters in the study were , clinical parameters ( body temperature , heartbeat , respiratory rate, body weight , in addition to monitor any abnormal signs appear on the animals . While the main hematological parameters were included , RBC count , WBC count , Hb concentration,PCV percentage , Red cell indices , Bleeding time and Clotting time. The body temperature, respiratory rates, heart rate were increased .The body weight decreased .The bleeding time and clotting time were prolonged. The erythrocyte count, Hb concentration, and MCV values were decreased; PCV and MCHC did not showed any significant changes. The MCH increased. The total leucocytes count and the basophiles percentage did not showed any significant changes. The Heterophils and monocytes percentage increased .The lymphocytic and Eosinophil percentage were decreased during the study.

scholarly journals The Effect of Aerobic and Core Exercises on Forced Vital Capacity

2018 ◽  
Vol 77 (1) ◽  
pp. 41-47 ◽  
Author(s):  
Güner Çiçek ◽  
Abdullah Güllü ◽  
Esin Güllü ◽  
Faruk Yamaner
Keyword(s):  
Forced Vital Capacity ◽  
Vital Capacity ◽  
Maximal Oxygen Consumption ◽  
Exercise Program ◽  
Exercise Group ◽  
T Test ◽  
Forced Expiration ◽  
Core Strength ◽  
Strength Exercises ◽  
Sedentary Women

Abstract The aim of the study was to investigate the effect of aerobic and core strength exercises on forced vital capacity in sedentary women. A total of 40 healthy sedentary women (20 in an aerobic-step group and 20 in a core strength exercise group) with a mean age of 34.4±2.4 years participated voluntarily in this study. Two different exercises were applied to the women for 12 weeks, 4 days a week, at the intensity of 70% for 60 minutes. The women's resting heart rate (RHR), maximal oxygen consumption (VO2max), forced vital capacity (FVC), and forced air volume in the first second of forced expiration (FEV1) were measured before and after exercise. For statistical analysis, the Paired Samples-t test was used for intra-group evaluations, and the Independent Samples-t test was used for inter-group evaluations. After the exercise program, significant increases were found in the VO2max, FVC, and FEV1 values, while both groups experienced a decreased RHR (p<0.01). Since the aerobic and forced vital capacities of the sedentary women show a parallel increase as a result of the applied 12-week aerobic and core strength exercises, it can be said that the RHR, VO2maxmax, FEV, and FEV1 respiratory parameters also improved in a positive manner. For this reason, it may be advisable to apply both exercise types for the development of the aerobic and vital capacities of sedentary women.

The Combination of Aerobic and Resistance Exercise Induces Weight Loss via the PGC-1α/Irisin/UCP-1 Pathway

2019 ◽  
Vol 9 (10) ◽  
pp. 1388-1394
Author(s):  
Hong Deng ◽  
Wei Zhang ◽  
Dingguo Ruan ◽  
Dezhi Chen ◽  
Xiaoyang Xu ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Resistance Exercise ◽  
Aerobic Exercise ◽  
Human Subjects ◽  
Blood Lipid ◽  
The Body ◽  
Lipid Levels ◽  
Reduced Body ◽  
Blood Lipid Levels

Obesity is a modern disease and the cause is quite complicated. This study explores the effects of aerobic and resistance exercise on weight loss and their relationship with the PGC-1α/Irisin/UCP-1 signaling pathway. First, we selected 52 obese students for aerobic and resistance exercise. Second, we established an obesity rat model, and then subjected them to 12 weeks of aerobic and resistance exercise. The body weights and blood lipid contents of all the subjects were measured, and mRNA and protein expressions were determined via real-time PCR and western blot. In obese students, aerobic exercise and the combination of aerobic and resistance exercise significantly reduced body weight and blood lipid levels. In obese model rats, aerobic and resistance exercise significantly reduced the body weight, blood lipid levels, and increased the PGC-1, Irisin, and UCP-1 levels. Furthermore, the combined effects of aerobic and resistance exercise were similar to those of prolonged aerobic exercise in both human subjects and model rats. The mechanism of weight loss via aerobic and resistance exercise may be related to the PGC-1α/Irisin/UCP-1 pathway, and the combination of aerobic and resistance exercise may be a more suitable weight loss option for obese patients.

scholarly journals PO-221 Effects of different motor functional therapies on cognitive impairment in type 2 diabetes mellitus

2018 ◽  
Vol 1 (5) ◽  
Author(s):  
Yu Zhou
Keyword(s):  
Type 2 Diabetes ◽  
Body Weight ◽  
Cognitive Impairment ◽  
Oxygen Uptake ◽  
Elderly Patients ◽  
Resistance Exercise ◽  
Aerobic Exercise ◽  
Exercise Group ◽  
Control Group

Objective The clinical manifestations of diabetic cognitive dysfunction are decreased visual spatial ability, executive dysfunction, mental activity speed and attention, and decreased abstract logical reasoning. Cognitive dysfunction is irreversible. Timely and accurate assessment and diagnosis, early detection and intervention to delay disease progression are particularly critical. The Cognitive Assessment Scale plays an important role in screening for cognitive dysfunction in diabetes. To observe the effects of motor functional therapy on cognitive impairment and blood glucose, blood lipids, body weight, body composition, and maximal oxygen uptake in patients with type 2 diabetes. Methods A total of 63 elderly patients with type 2 diabetes mellitus in Chengdu community aged ≥65 years and educated for ≥12 years were enrolled in the motor function therapy group according to the simple mental state examination (MMSE) score (diabetes cognitive impairment, MMSE total score) ≥ 20 points, aerobic exercise group, n = 21) and functional function therapy group (diabetes cognitive impairment, MMSE total score ≥ 20 points, resistance exercise group, n = 21). The adult community of diabetes in Chengdu (normal cognitive function) with age ≥ 65 years, education time ≥ 12 years, and MMSE total score ≥ 24 points was used as the control group (n=21). Montreal Cognitive Assessment Scale (MOCA): MOCA is an assessment tool developed by Nasreddine and clinically proven to be used for rapid screening of MCI. There were no statistical differences in baseline data (age, gender, and hypertension incidence) among the 3 groups of patients. The LOTCA scale was used to evaluate the cognitive function of the subjects and to compare between groups. Sixty-three patients with type 2 diabetes were randomly divided into aerobic exercise intensity group (50% VO2max) (n=21), resistance exercise intensity group and control group (n=21). Both the aerobic exercise group and the resistance exercise group underwent a 12-week moderate-intensity exercise three times a week. The resistance middle strength group was trained 2 groups each time, each group was 25 minutes, the group rested for 5 minutes, 55 minutes in total, and the aerobic medium intensity group continued to exercise for 55 minutes. All patients underwent fasting blood glucose (FPG), glycosylated hemoglobin (HbA1c), total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), body weight, and fat weight (FW) before and after training. , lean body mass (LBM), maximal oxygen uptake (VO2max) determination; measure the energy expenditure of word movement and the total energy expenditure of the entire exercise process. Results There were no significant differences among the three groups before the test (P>0.05). All the indexes of the medium-intensity resistance exercise group and the medium-intensity aerobic exercise group were significantly different from the control group (P<0.05). After the MOCA score test There was an improvement in the score before the trial, and the total score of LOTCA was significantly different among the three groups. In addition to perceptual sub-items (item identification), the aerobic exercise group and the resistance exercise group LOTCA scale in perceptual sub-projects (incomplete object recognition), visual motion organization and its sub-projects (copying two-dimensional graphics, building blocks) The design and puzzle) project scores were higher than before the test, close to the control group score. The scores of the two groups of exercise therapy in the thinking operation and its sub-projects (Riska organized shape classification, picture arrangement B and geometric reasoning) and attention-focused items were lower than the control group. Compared with the resistance exercise, there was a significant difference in the maximum oxygen uptake between aerobic exercise and resistance exercise (P<0.05). Compared with the total exercise energy consumption in the first 6 weeks, the aerobic exercise group was superior to the resistance exercise group. The total exercise energy expenditure was compared in the last 6 weeks, and the resistance exercise group was superior to the aerobic exercise group. Conclusions Elderly patients with type 2 diabetes may have cognitive impairment earlier. In the absence of differences in exercise, the aerobic exercise group and the resistance exercise group improve cognitive impairment, blood sugar, blood fat, body weight, and body composition in patients with type 2 diabetes. There is no significant difference. Compared with MMSE, LOTCA has the advantage of identifying early cognitive impairment in elderly patients with type 2 diabetes and distinguishing the severity of the damage.  

scholarly journals Load progression in strength exercises through a physical combined training program for elderly people

2019 ◽  
Author(s):  
Victor Bueno Gadelha ◽  
Mara Patricia Traina Chacon Mikahil ◽  
Amanda Veiga Sardeli ◽  
Wellington M. Santos ◽  
Daisa F. G. Moraes ◽  
...  
Keyword(s):  
Strength Training ◽  
Aerobic Exercise ◽  
Training Session ◽  
Knee Extension ◽  
Strength Exercise ◽  
Combined Training ◽  
Strength Exercises ◽  
Muscle Groups ◽  
And Gender ◽  
Training Protocol

The objective of this study was to investigate how many strength training sessions would be necessary to achieve significant increase in load. A group of 7 men and 14 women over 60 years old were recruited for the survey. The participants underwent combined training (strength and aerobic exercise), with 2 sessions of strength exercise and 3 sessions of aerobic exercise per week during 16 weeks. The strength exercise was composed of 5 exercises for the main muscle groups (knee extension, knee curl, leg press, bench press, high pull), 1 set of 15 repetitions was performed for each exercise. The aerobic exercise consisted of continuous walking/running on a treadmill, at 60% of the VO2 reserve, for 50 minutes. The loads were recorded at each training session. Participants were encouraged to always score between 7 and 8 on the effort perception scale (0 to 10). In the present study we observed that both genders had an increase in the amount of load used. The combined training protocol is capable of increase the load in the strength training in the first 8 training sessions differentianting between exercises and gender.

Sign in / Sign up

Export Citation Format

Share Document