Understand the Patients’ Attitude towards Presbyopia and the various Lenses Correction Options

2021 ◽  
Author(s):  
Aditya Tripathi
Keyword(s):  
Contact Lenses ◽  
Point Of View ◽  
North India ◽  
Aged Group ◽  
Age Related ◽  
Feedback Questionnaire ◽  
Progressive Addition Lenses ◽  
Bifocal Lenses ◽  
Presbyopia Correction ◽  
Selection Of

Aim: To reveal the patients point of view about the selection of different presbyopic correction options from ophthalmic lenses and awareness about presbyopia. Methodology: In this Prospective study, feedback questionnaire based study in North India, 126 subjects were enrolled and the offline questionnaire and responses were recorded. Participants’ age ranged between 37 -75 years (using near correction). Evaluated the responses to know the reasons of chosen of different options for pre-presbyopia and presbyopia correction by the subjects and attitudes about it, its importance, and present conventional correction opinions including bifocals, progressive addition lenses and contact lenses. Result: Among the all participants, number of participants between the age group 37- 45 (pre-presbyopes) were 35 (27.77%), between 45-55 years of aged group were 60 (47.61%) participants and rest of 31 (24.60%) participants were between 55-75 years of aged group. Forty eight participants (38.1%) were already wearing a near correction while seventy eight (61.9%) were not wear any near correction. Out of 126, the 6 (4.76%) subjects were chosen a near visual correction and separated glasses, 88 (69.84%) subjects were chosen the bifocal lenses, rest of all 32 (25.89%) subjects chosen the PALs. And no one was using contact lens for near correction. Few similarities were observed as age–related (75.38%), total unaware of word presbyopia (85.71%), comfort, convenience and appearance concerned (63%). Conclusion: The spectacles were most preferred for the correction of presbyopia. Bifocals are taken by majority of population. After educating about Presbyopia and advantages of PALs, it was revealed that most of the subjects wanted to choose PALs because of comfort and convenience to see all distances but most of them denied due to cost and 4-8 days adaptation time. So most of the subjects were chosen the bifocal lenses even they knew the disadvantages of it like image jump and segment line, while comfort, convenience and cosmetic appearance were seen as the preferred than cost. But cost also played role while finalize the lens and its coatings types.

Tauchnitz for Translators. The Circulation of English-language Literature in Finland

2019 ◽  
Vol 16 (2-3) ◽  
pp. 161-179
Author(s):  
Outi Paloposki
Keyword(s):  
Foreign Language ◽  
English Language ◽  
Book History ◽  
Language Skills ◽  
Point Of View ◽  
Book Production ◽  
German Publisher ◽  
Language Literature ◽  
Selection Of

The article looks at book production and circulation from the point of view of translators, who, as purchasers and readers of foreign-language books, are an important mediating force in the selection of literature for translation. Taking the German publisher Tauchnitz's series ‘Collection of British Authors’ and its circulation in Finland in the nineteenth and early twentieth century as a case in point, the article argues that the increased availability of English-language books facilitated the acquiring and honing of translators' language skills and gradually diminished the need for indirect translating. Book history and translation studies meet here in an examination of the role of the Collection in Finnish translators' work.

COMBINATORIAL POLYNOMIALLY COMPUTABLE CHARACTERISTICS OF SUBSTITUTIONS AND THEIR PROPERTIES

2020 ◽  
Vol 7 (2) ◽  
pp. 34-41
Author(s):  
VLADIMIR NIKONOV ◽  
◽  
ANTON ZOBOV ◽  
Keyword(s):  
Mathematical Expectation ◽  
Point Of View ◽  
Small Range ◽  
Computational Point ◽  
Wide Range ◽  
Bijective Function ◽  
The Difference ◽  
Element Base ◽  
Selection Of

The construction and selection of a suitable bijective function, that is, substitution, is now becoming an important applied task, particularly for building block encryption systems. Many articles have suggested using different approaches to determining the quality of substitution, but most of them are highly computationally complex. The solution of this problem will significantly expand the range of methods for constructing and analyzing scheme in information protection systems. The purpose of research is to find easily measurable characteristics of substitutions, allowing to evaluate their quality, and also measures of the proximity of a particular substitutions to a random one, or its distance from it. For this purpose, several characteristics were proposed in this work: difference and polynomial, and their mathematical expectation was found, as well as variance for the difference characteristic. This allows us to make a conclusion about its quality by comparing the result of calculating the characteristic for a particular substitution with the calculated mathematical expectation. From a computational point of view, the thesises of the article are of exceptional interest due to the simplicity of the algorithm for quantifying the quality of bijective function substitutions. By its nature, the operation of calculating the difference characteristic carries out a simple summation of integer terms in a fixed and small range. Such an operation, both in the modern and in the prospective element base, is embedded in the logic of a wide range of functional elements, especially when implementing computational actions in the optical range, or on other carriers related to the field of nanotechnology.

Der Sommer und Herbst 2003 aus phänologischer Sicht | Summer and autumn 2003 from a phenological point of view

2004 ◽  
Vol 155 (5) ◽  
pp. 142-145 ◽  
Author(s):  
Claudio Defila
Keyword(s):  
Time Series ◽  
New Record ◽  
Point Of View ◽  
Late Spring ◽  
Mean Deviation ◽  
Leaf Shedding ◽  
The Mean ◽  
Very High ◽  
Selection Of

The record-breaking heatwave of 2003 also had an impact on the vegetation in Switzerland. To examine its influences seven phenological late spring and summer phases were evaluated together with six phases in the autumn from a selection of stations. 30% of the 122 chosen phenological time series in late spring and summer phases set a new record (earliest arrival). The proportion of very early arrivals is very high and the mean deviation from the norm is between 10 and 20 days. The situation was less extreme in autumn, where 20% of the 103 time series chosen set a new record. The majority of the phenological arrivals were found in the class «normal» but the class«very early» is still well represented. The mean precocity lies between five and twenty days. As far as the leaf shedding of the beech is concerned, there was even a slight delay of around six days. The evaluation serves to show that the heatwave of 2003 strongly influenced the phenological events of summer and spring.

Design of Inhibitors for Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Enzyme of Leishmania mexicana

2020 ◽  
Vol 16 (6) ◽  
pp. 784-795
Author(s):  
Krisnna M.A. Alves ◽  
Fábio José Bonfim Cardoso ◽  
Kathia M. Honorio ◽  
Fábio A. de Molfetta
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulations ◽  
Binding Site ◽  
Point Of View ◽  
New Drugs ◽  
Leishmania Mexicana ◽  
Receptor Complexes ◽  
Starting Point ◽  
Dynamics Simulations ◽  
Selection Of

Background:: Leishmaniosis is a neglected tropical disease and glyceraldehyde 3- phosphate dehydrogenase (GAPDH) is a key enzyme in the design of new drugs to fight this disease. Objective:: The present study aimed to evaluate potential inhibitors of GAPDH enzyme found in Leishmania mexicana (L. mexicana). Methods: A search for novel antileishmanial molecules was carried out based on similarities from the pharmacophoric point of view related to the binding site of the crystallographic enzyme using the ZINCPharmer server. The molecules selected in this screening were subjected to molecular docking and molecular dynamics simulations. Results:: Consensual analysis of the docking energy values was performed, resulting in the selection of ten compounds. These ligand-receptor complexes were visually inspected in order to analyze the main interactions and subjected to toxicophoric evaluation, culminating in the selection of three compounds, which were subsequently submitted to molecular dynamics simulations. The docking results showed that the selected compounds interacted with GAPDH from L. mexicana, especially by hydrogen bonds with Cys166, Arg249, His194, Thr167, and Thr226. From the results obtained from molecular dynamics, it was observed that one of the loop regions, corresponding to the residues 195-222, can be related to the fitting of the substrate at the binding site, assisting in the positioning and the molecular recognition via residues responsible for the catalytic activity. Conclusion:: he use of molecular modeling techniques enabled the identification of promising compounds as inhibitors of the GAPDH enzyme from L. mexicana, and the results obtained here can serve as a starting point to design new and more effective compounds than those currently available.

Analysis of the Most Valued Organization to Work for in Spain, According to Nationality and Location

2019 ◽  
Vol 5 (2) ◽  
pp. 83-99
Author(s):  
Francisco Jesús Ferreiro Seoane ◽  
Manuel Octavio Del Campo Villares
Keyword(s):  
Work Environment ◽  
Talent Management ◽  
Point Of View ◽  
Added Value ◽  
Quantitative Character ◽  
Autonomous Communities ◽  
Professional Performance ◽  
Significant Relationships ◽  
Pearson Correlations ◽  
Selection Of

Background: The objective of this article is to analyse if there are significant relationships between the most valuable companies operating in Spain regarding professional performance, according to nationality and location within their Autonomous Communities or any superior aggrupation. To do that, a sample of 100 companies has been selected. Methods: The methodology followed is based on the selection of the 100 highestvalued companies from the point of view of Human Resources’ policy for the period 2013-2016 and through the measurement of six factors: Talent Management, Retribution, Work environment, CSR, Training and Employees’ perception, and classified by nationality and location. The study was based on 12 hypotheses, using the Unifactorial Variance’s Analysis, Pearson correlations and regressions. One limitation could be the fact that this study refers to a particular period, focusing on Spain and the variables mentioned, based on questionnaires. The added value of this work lies on the newness as it has a quantitative character, and on the fact that most of the hypotheses do not comply. Results and Conclusion: This allows to deny certain beliefs that affirm that European and American companies operating in Spain are more attractive than the Spanish or the Mediterranean ones.

scholarly journals The Use of Statistical Functions for the Selection of Laser Texturing Parameters

2020 ◽  
Vol 10 (1) ◽  
pp. 454-461
Author(s):  
Piotr Sęk
Keyword(s):  
Surface Texturing ◽  
Point Of View ◽  
Laser Surface Texturing ◽  
Machining Parameters ◽  
Textured Surfaces ◽  
Surface Layers ◽  
Adhesion Properties ◽  
Machine Elements ◽  
Selection Of ◽  
Statistical Functions

AbstractLaser surface texturing is currently the most developed technique for producing fully reproducible microcavities on the surfaces of machine elements. From the point of view of texture technology, an important aspect is the proper selection of process parameters to obtain texture elements with desirable and repetitive geometries and physicochemical properties. Surface texturing improves mottling and fretting resistance and is also used wherever the adhesion properties of surface layers (printing techniques, bonding materials, biological and chemical activity, coatings, etc.) are important. The article shows the possibility of applying statistical functions to the selection of appropriate machining parameters to obtain microgeometry useful in the application of textured surfaces [1].

scholarly journals Influence of Patient Age on Streptococcus pneumoniae Serotypes Causing Invasive Disease

2001 ◽  
Vol 8 (3) ◽  
pp. 556-559 ◽  
Author(s):  
Jaime Inostroza ◽  
Ana Maria Vinet ◽  
Gloria Retamal ◽  
Pedro Lorca ◽  
Gonzalo Ossa ◽  
...  
Keyword(s):  
Age Groups ◽  
Invasive Disease ◽  
Bacterial Virulence ◽  
Host Factors ◽  
Invasive Infection ◽  
Age Group ◽  
Southern Chile ◽  
Age Related ◽  
Sterile Site ◽  
Selection Of

ABSTRACT All clinical S. pneumoniae specimens isolated from patients with invasive or sterile-site infections admitted to one regional general hospital in southern Chile were collected during a 5-year period (February 1994 to September 1999). A total of 247 strains belonging to 50 serotypes were isolated in this survey: 69 in patients under 5 years of age, 129 in patients 5 to 64 years old, and 49 from patients 65 years and older. Eight serotypes were identified in all age groups, while all other serotypes were found exclusively in one age group or in patients over 4 years of age. Serotype 3 was never found in patients under 5 years old, and serotype 14 was not found in patients >64 years of age. There was no difference in the serotypes causing infection in each one of the 5 years of the survey. Our results suggest that both bacterial virulence factors and host factors play an important role in the selection of S. pneumoniae serotypes causing invasive infection. Possible host factors include age-related differences in the immune response. Comparative studies with other areas of the world may help to further understanding of our observations in southern Chile.

The Comparison Between Therapeutic Effects of Different Classes of Antidepressant Drugs in Treatment of Genetical and Reactional Depression

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
P. Molavi ◽  
M. Karimollahi ◽  
M. Faridi
Keyword(s):  
Antidepressant Drugs ◽  
Response Speed ◽  
Point Of View ◽  
Block Type ◽  
Therapeutic Effects ◽  
Response Type ◽  
Analysis Method ◽  
Dsm Iv ◽  
Selection Of ◽  
Analyze Data

Background:Depression as a common psychiatric disorder can occur in two types: Endogenous or genetic and exogenous or Reactional. These two types of depression, from the point of view of response speed to treatment and type of appropriate drug for treatment are different. This study has been executed to compare therapeutic effects of different classes of anti-depressant drugs in treatment of genetic and Reactional depression.Materials and methods:Present survey is a clinical-trial study, a completely randomly block type, that has performed on 30 patients (male and female). Selection of study sample accomplished randomly among unipolar depressed patients that has referred to Ardabil’s psychiatry clinic diagnosed based on DSM-IV criteria. Researcher - Made questionnaire, Beck, and Catelle depression test were used to collect data. To analyze data, for completely randomly blocked designs, two-factor variance analysis method and F test were used.Results:This study showed that Genetical depression does not response treatment Rapidly and its response type is not good and persistent. From the point of view of time, Reactional depression has a delaying response but its response type is good and persistent. In addition, no difference was observed in efficacy of different classes of drugs for treatment of these two types of depression. The results of this research showed that there is no difference between treatment response of two types of depression (Genetical and Reactional).Conclusions:There is no preference in efficacy of different classes of drugs in treatment of these two types of depression.

LINGUOCULTURAL POTENTIAL OF EUPHEMISMS-AMULETS

2021 ◽  
pp. 68-74
Author(s):  
SERGEY I. ROMANOV ◽  
Keyword(s):  
Target Selection ◽  
Cultural Factors ◽  
Point Of View ◽  
Negative Consequences ◽  
Cultural Community ◽  
Magical Power ◽  
Selection For ◽  
Cultural Code ◽  
Russian Linguistic ◽  
Selection Of

The article deals with a special type of euphemisms-amulets, that is, linguocultural units endowed with the function of protection. There are two types of euphemisms-amulets from the point of view of relevance: obsolete and current units. Obsolete euphemisms- amulets have targets that are not recognized as dangerous by the modern linguistic and cultural community. Current euphemisms-amulets, although not always consciously, are used by representatives of the modern Russian linguistic and cultural community to protect against something bad. The paper establishes that the use of the euphemism-amulet is based on the transla- tion of the target's representation into another cultural code. The work reveals that the euphemisms-amulets are directed not to mitigate an unwanted nomination but how to replace it. An undesirable nomination is endowed with negative magical properties, which is why the linguocultural community imposes a ban on its use. A protective cultural function is superim- posed on the euphemism. The main pragmatic explanation for the use of the euphemism- amulet is the speaker's desire not to predict an encounter with an unwanted object, which is based on belief in the magical power of the word. The factors that determine the linguocultural specificity of euphemisms-amulets are revealed. The first factor is target selection. For the Russian linguocultural community, such targets include a totemic animal, evil forces representing another world, death. The second factor is the selection of nominations for the euphemistic function, which is determined by culturally marked background knowledge, ideas, and typical practices. The communicative- pragmatic platform for the use of euphemisms-amulets is the belief in the magical power of the word, in the fact that the use of the forbidden word can lead to negative consequences (in particular, to cause the appearance of something dangerous, undesirable). The work proves that the identified cultural factors are universal, based on universal archetypes: one's own / another's, permission / prohibition, life / death. At the same time, the fact of the appearance of the euphemism-amulet, the choice of its internal form is determined by national and cultural factors.

A Geomorphological Approach to Geodiversity and Geotourism in Uttarakhand Himalaya, India: A Pilot Survey 

2021 ◽  
Author(s):  
Anita Pande
Keyword(s):  
The State ◽  
Point Of View ◽  
North India ◽  
Tethys Sea ◽  
Geomorphological Heritage ◽  
The World ◽  
Tectonic Boundaries ◽  
Geomorphological Features ◽  
Tectonic Origin ◽  
Uttarakhand Himalaya

<p>Himalaya is the greatest heritage of India. The objective of this paper is to present a view of the geomorphological heritage of the Himalaya.Uttarakhand<strong> </strong>state (77°35’5”-81°2’25” E and 28°43’45”-31°8’18’’N, Area: 53,066 sq.km.)<strong> </strong>lies almost wholly within the realm of the Himalaya and is a distinct geographical entity. The state is a land of vast geological and topographic diversities and a realm with rich geo-wealth and geoheritage. Geological and geomorphological features occurring in different parts of Uttarakhand Himalaya are part of the natural assets and are precious state heritage (geoheritage), worthy of conservation. Apart from rock monuments and fossil parks, geomorphological features or geomorphosites have great potential to exert a pull on tourists. These sites have noteworthy impact on the geoscience education and research. Geotourism is growing rapidly all over the world and Himalaya region is no exception to this. To promote geotourism in the Himalayan State of Uttarakhand, comprehensive information about geomorphosites should be made available to the tourists by way of websites. For this, first a peer-reviewed state inventory of geomorphosites and their classification, mapping and assessment is required. Geodiversity in Uttarakhand State can best be understood in the form of the rise of Himalayan mountains from the bed of Tethys Sea which gave rise to four distinct tectonic units largely varying in lithology and structure. The relief was fragmented into four major morphosculptural units which signify the mountainous part of the state: viz. i. the Tethys zone or the Trans-Himalaya ii. the Greater Himalaya iii. the Lesser Himalaya and iv. the Siwalik. Apart from this mountainous region of the State, there is  outlying region of the state, which incompasses : iv. Bhabhar and Tarai (a sub-montane tract) - a landscape feature along the foothills, v. Dun Valleys – valleys of tectonic origin and vi. Plains of North India - the lowest part in Uttarakhand with an altitude of 200 m. These geological units recognised on the basis of evolutionary history, stratigraphic sequences and component rock units and reveal identical topographic and climatic characteristics. These units are separated by various tectonic boundaries. Apart from geodiversity, the geomorphological diversity can be assessed in the form of towering snow peaks, awe-inspiring horned peaks with natural grandeur, widely distributed stretches of wide and fertile valleys, valleys of tectonic origin-canoe shaped longitudinal valleys, lofty snow capped peak surrounded by several small and big snowfields, glaciers and lakes, mountain passes and  elevated zones packed in a series of multi-level distinctive waterfalls. Thus, being the youngest mountain of the world, this Himalayan State has geotouristic potential from the point of view of its geomorphological heritage.</p><p><strong> </strong><strong>Keywords: </strong>Himalaya<strong>, </strong>geodiversity , geomorphological heritage, geomorphosites, geotourism.  </p>

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