scholarly journals Analisa Faktor Risiko Penyebab Kejadian Penyakit Gagal Ginjal Kronik (GGK) Di Ruang Hemodialisa RS Dr. Moewardi

2018 ◽  
Vol 3 (1) ◽  
Author(s):  
Siti Purwati

Background: Chronic renal failure is a disease that affects many people of Indonesia. CRF is caused by several risk factors such as age, sex, smoking history, history of hypertension, history of diabetes, history of consumption analgesic / NSAID, history of energy drink supplement consumption. Based on medical record data RS Dr. Moewardi Surakarta number of patients with chronic renal failure in 2015 was 1023 patients. The purpose of this research was to analyze the risk factors associated with disease occurrence of CRF in RS Dr. Moewardi. Method: Research design used in this study design was descriptive analytic with cross-sectional design. The total sample of 60 respondents from patients with CRF in Space Hemodialysis in RS Dr. Moewardi in March and April 2016 used univariate frequency distribution, bivariate chi-square, multivariate logistic regression. Result: this research showed the highest frequency distribution is equal to the age of more than 60 years of 91,7%, male gender 53,3%, 53,3% smoking history, history of hypertension of 75,0%, a history of DM 55 %, a history of consumption of analgesics/NSAIDs 53,3%, a history of consumption of 90,0% supplement drink. Bivariate analysis showed significant association between the occurrence of CRF stage 5 with age (p-value 0.039), gender (p-value 0.036), history of smoking (p-value 0.036), hypertension (p-value 0.021), DM (p-value 0.016), consumption of analgesics/ NSAID (p-value 0.001), supplement beverage consumption (p-value 0.008 ). Results of multivariate analysis found the most dominant factor in the incidence of CRF stage 5 is a history of consumption of supplement drink with OR = 35.791. risk factors most dominant factor is a history of consumption of beverage supplements.

2020 ◽  
Vol 10 (2) ◽  
pp. 80-88
Author(s):  
Sara Sara Tania Aprianty ◽  
Hani Siti Hanifatun Fajria

Chronic Renal Failure (CRF) is a disease that has occurred after various diseases that damage the kidney nephrons period up to the point the two are not capable of functioning regulatory and ekstetoriknya to maintain homeostasis. Number of patients with kidney failure in Indonesia is estimated to reach 300.000 people. As many as 12.804 patients with renal failure undergoing hemodialysis. To determine correlation family support patient compliance with chronic renal failure undergo hemodialysis therapy in RS PMI Bogor. This type of research is descriptive quantitative analytical research with cross sectional design. How sampling in this study with purposive sampling with a sample of 152 respondents. The instrument used is questionnaire while data analysis techniques using univariate and bivariate analysis using statistical test Chi-Square. Of the 152 respondents with a family to support as many as 139 respondents (91.4%), adherent patients as many as 128 respondents (84.2%) and family support with adherent patients as many as 121 respondents (79.6%). Statistical test results using Chi-square test p value value 0,007 (p <0.05) and the value of OR 5.762. The conclusion of this research that, There is a correlation between family support patient compliance with chronic renal failure through hemodialysis therapy in PMI Hospital Bogor, 2016. The researchers recommend that increased family support by distributing leaflets to the patients and families about the importance of family support for compliance patients undergo hemodialysis therapy.


Author(s):  
Prachi Dubey ◽  
Sanjay Varma ◽  
Bhuwan Sharma

Background: Patients with chronic kidney disease have impaired immunity due to disease per se and because of immunosuppressant treatment used for their disease. Catheters used for hemodialysis acts as conduit for microorganisms to cause infections. This leads to increase in morbidity and mortality.Methods: 100 patients of renal failure requiring hemodialysis were selected. Relevant pathological and radiological investigation done to rule out already existing infection, later on tests were repeated after catheter insertion and hemodialysis to check for infection and sepsis. Using appropriate statistical analysis was done and p value <0.05 was taken as significant.Results: Out of 100 patients underwent study, 15 developed catheter related blood stream infection. Older age, history of diabetes, male sex, diabetes, anemia, hypoalbuminemia, hyperphosphatemia, prolonged duration of hemodialysis and site of hemodialysis catheter were found to be risk factor for infection.Conclusions: Patients requiring hemodialysis, who are having non modifiable risk factors like age, sex other risk factors for infection should be controlled to reduce incidence of infection. 


2017 ◽  
Vol 5 (1) ◽  
pp. 48-56
Author(s):  
Wayunah . ◽  
Neneng Ratnanengsih Puspitasari ◽  
Fatikhatul Jannah

Gagal ginjal kronik merupakan suatu kondisi dimana ginjal mengalami penurunan fungsi yang terjadi secara progresif dan irreversible. Banyak faktor yang dapat menyebabkan GGK pada pasien usia < 45 tahun. Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan kejadian GGK pada pasien usia < 45 tahun. Penelitian ini dilakukan dengan pendekatan case study. Sampel dipilih dengan tekhnik counsecutive sampling, dengan jumlah 98 responden. Alat pengumpul data dalam penelitian ini menggunakan kuesioner. Analisis data bivariat yang digunakan dalam penelitian ini adalah uji chi square. Hasil penelitian diketahui faktor yang berhubungan adalah faktor riwayat penyakit diabetes mellitus (p value = 0,002). Sedangkan faktor yang tidak berhubungan adalah faktor zat kimia (p value = 0,295), faktor kurang asupan cairan (p value = 0,366), faktor riwayat hipertensi (p value = 0,518) dan faktor riwayat obstruksi saluran kemih (p value = 0,312). Simpulan dalam penelitian ini faktor yang berhubungan adalah diabates mellitus dan faktor yang tidak berhubungan adalah konsumsi zat kimia, kurang asupan cairan, riwayat penyakit hipertensi dan riwayat penyakit obstruksi saluran kemih. Saran dalam penelitian ini ditujukan kepada perawat untuk meningkatkan edukasi kepada masyarakat tentang pencegahan terjadinya GGK. Abstrak Chronic Renal Failure is a condition that decreasing kidney function, occurning progresive and irreversible. Many factors causes CRF in patiens aged < 45 years. Purpose of this study was to determine the factors associated with the occurrence of CRF in patiens age < 45 years.This research was conducted with case study approach. Samples selected with counsecutive technique sampling with 98 respondents. Data collection, this study using a questionnaire. The bivariae data analysis used in this study is the chi square test. The results is known factors associacted with in a diabetes mellitus of history factor (p value = 0,002) while factor unrelated chemical substances is a factor ( p value = 0,925), less intake of fluids factor (p value = 0,366), hypertension of history factor ( p value = 0,518) and history of obstruction of tract urinary factor (p value = 0,312). Conclusions in this research that there is a relationship between the factors of history of diabetes mellitus with chronic renal failure event in patients aged < 45 years. Suggestions in this study was shown to the nurse to increase public education about the prevention of the occurance of CRF.


2019 ◽  
Vol 3 (12) ◽  
pp. 493-496
Author(s):  
Monitrya Nababan ◽  
Achmad Lefi ◽  
Djohar Nuswantoro

Objective: To determine the relationship of coronary heart disease traditional risk factors to the number of lesioned coronary arteries and calculate the relative risk. Methods: This study used an analytical research design with a retrospective cohort study design using patient catheterization report data. Data analysis was performed using the chi square test and relative risk in 449 individuals. Results: Based on the analysis results obtained p value 0.05 indicating no relationship between risk factors for coronary heart disease with the number of coronary arteries the lesions based on sex, history of hypertension and history of smoking. Conclusion: There is a relationship between age, history of diabetes mellitus, history of dyslipidemia and the number of coronary arteries that are lesions in patients with coronary heart disease and there is no relationship between sex, history of hypertension and smoking history with the number of coronary arteries that are lesions in patients with coronary heart disease. Keywords: single vessel disease; multivessel disease; coronary artery disease; risk factors CAD


Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 105-105 ◽  
Author(s):  
Sabarish Ram Ayyappan ◽  
Akiva Diamond ◽  
Vinita Gupta ◽  
Brenda Cooper ◽  
Ben K. Tomlinson ◽  
...  

Abstract Diffuse large B cell lymphoma (DLBCL) is the most frequent non-Hodgkin lymphoma, with increasing incidence in the elderly population. Anthracycline-containing chemo immunotherapy can achieve high response rates and improved survival, but can result in cardiovascular toxicity, which can negatively affect short and long term survival, particularly in older patients. We conducted a retrospective analysis to determine the incidence of cardiovascular events after DLBCL and the effect these complications have on outcomes. Methods: The Hematologic Malignancies Database of University Hospitals Seidman Cancer Center was accessed to identify newly diagnosed DLBCL patients between 2002 and 2014. Data on patient characteristics including cardiovascular risk factors, disease characteristics, baseline cardiac function, treatment details, and outcomes including response, relapse and cardiovascular events was collected. Univariate Cox proportional hazards analysis was conducted on risk factors and those reaching statistical significance (p < 0.05) were selected for inclusion in multivariate proportional hazards model to help identify predictors for cardiovascular events. Cumulative incidence (with death as competing risk) was used to estimate the incidence of cardiovascular events. Overall survival (OS) and progression free survival (PFS) was calculated using the Kaplan-Meier method, and comparison between groups was done with the log rank test. Results: Four hundred DLBCL patients were included for analysis. Median age at diagnosis was 63 years, with 139 patients above the age of 70. 237 patients (59.3 %) had advanced disease (Ann Arbor stage III/IV) at diagnosis and 28 (7 %) patients had left ventricular ejection fraction less than 50 % at baseline. Other baseline characteristics are listed in Table 1. Treatment included an anthracycline-based regimen in 319 (86.3%) patients and 338 (92%) patients received rituximab. 274 (81%) patients achieved complete remission and 39 (11.5%) patients had progressive disease. After a median follow up of 33 months, 190 patients had relapsed and 140 died. The overall 3-year PFS for the cohort was 57.6 % (95 % CI 52.4- 62.7 %) and 3-year OS 69.8 % (95 % CI 65-74.7%). Seventy four patients developed cardiovascular events, with 1-year and 3-year cumulative incidence of 9.7% (95 % CI 7.1-13.2) and 14.7 % (95 % CI 11.5 -18.9), respectively. Fifty-two patients (13 %) developed congestive heart failure, nine (2.25 %) were diagnosed with new coronary artery disease requiring revascularization and six patients (1.5 %) suffered new cerebrovascular accident. Table 2 summarizes the results of Cox proportional hazards analysis. Univariate analysis showed age > 60 years, previous history of congestive heart failure, coronary artery disease, arterial hypertension, COPD, chronic renal failure and BMI > 30 were significantly associated with cardiovascular events (p<0.05). In multivariate analysis, only age > 60 years, BMI >30 and history of chronic renal failure showed statistical significance (p = 0.016, 0.002, 0.031 respectively). Patients who presented a cardiovascular event less than 1 year after DLBCL diagnosis had an estimated 3-year OS of 49.2% (95 % CI 31-67.5 %) vs. 71.7% (95 % CI 66.8-76.6 %) in patients who did not experience early cardiovascular events (p=0.002) (Figure 1). Conclusions. DLBCL patients have an elevated incidence of cardiovascular events after diagnosis. Most cardiac complications occur early, within 1 year of diagnosis and treatment, and have a significant effect on long-term survival. Identification of the patients at highest risk is important for guiding risk-adapted monitoring, preventive measures and early intervention. In addition to known history of cardiac disease, we identified advanced age, increased BMI and history of chronic renal failure as additional risk factors that should be incorporated in cardiac risk stratification of patients receiving therapy for DLBCL. Disclosures Caimi: Roche: Research Funding; Gilead: Consultancy; Genentech: Speakers Bureau; Novartis: Consultancy.


2021 ◽  
Vol 15 (11) ◽  
pp. 3076-3077
Author(s):  
Fauzia Siraj ◽  
Rabbiah Manzoor Malik ◽  
Zafar Iqbal ◽  
Rifat Shamim ◽  
Attya Zaheer ◽  
...  

Aim: To study the frequency and factors associated with peritoneal involvement among patients operated for acute appendicitis in a tertiary care hospital. Place and duration of study: Department of Surgery, Benazir Bhutto Hospital Rawalpindi Pakistan from 1stJuly 2020 to 30thJune 2021. Methodology: This comparative cross-sectional study 500 patients diagnosed as acute appendicitis and operated by consultant surgeon were included. Peritoneal involvement was defined as signs of inflammation or infection on abdominal lining observed by operating surgeon during the time of surgery. Factors like age, gender, presence of comorbid illnesses and history of previous abdominal surgeries were associated with presence of peritoneal involvement. Results: There were 305 (61%) males while 195 (39%) were females with mean age was 32.331±4.544 years.Four hundred and forty two (88.4%) did not show any peritoneal involvement at the time of surgery while 58 (11.6%) had peritoneal involvement. Chi-square test revealed that history of previous abdominal surgeries and advancing age had statistically significant association with peritoneal involvement among the study participants (p-value<0.05). Conclusion: Peritoneal involvement was found in considerable number of patients operated as acute appendicitis by the treating surgeons. Patients with previous history of abdominal surgeries and advancing age were more at risk of having peritoneal involvement in our study. Keywords: Acuteappendicitis, Peritonitis, Risk factors, Frequency


2019 ◽  
Vol 11 (1) ◽  
pp. 9-18
Author(s):  
Abdul Wakhid ◽  
Ana Puji Astuti ◽  
Maya Kurnia Dewi

Logoterapi merupakan terapi untuk menemukan makna positif dibalik sebuah kejadian yang tidak diharapkan. Logoterapi dilaksanakan secara individu maupun berkelompok dalam bentuk konseling dan berorientasi pada pencarian makna hidup individu. Tujuan logoterapi meningkatkan makna pengalaman hidup individu yang diarahkan kepada pengambilan keputusan yang bertanggung jawab. Penelitian ini dilakukan dengan menggunakan rancangan pre-experiment dengan metode pre and post test group, artinya pengumpulan data dilakukan terhadap responden untuk membandingkan kualitas hidup sebelum dan sesudah dilakukan intervensi. Teknik pengambilan sampel dilakukan dengan metode total sampling yaitu pengambilan seluruh sampel dengan tetap memperhatikan kriteria yang telah ditetapkan. Jumlah pasien yang menjalani hemodialisis di RSUD Ungaran sebanyak 21 orang dan di RSUD Ambarawa sebanyak 25 pasien. Analisis data dilakukan dengan menggunakan uji t test dependent. Hasil penelitian didapatkan bahwa dari 46 responden didapatkan rata-rata skor kualitas hidup pasien yang mejalani hemodialisis sebesar 60.22 dengan skor terrendah 55 dan skor tertinggi 69. Bahwa dari 46 responden didapatkan rata-rata skor kualitas hidup pasien yang mejalani hemodialisis sebesar 88.72 dengan skor terrendah 79 dan skor tertinggi 103. Hasil uji statistik dengan uji t test dependent diketahui ada pengaruh logoterapi terhadap kemampuan memaknai hidup pada klien yang menjalani hemodialisis di RSUD Kabupaten Semarang (p value: 0,0001). Saran perlunya peningkatan kemampuan perawat dalam memberikan layanan kesehatan termasuk pemberian atau pemanduan penemuan makna hidup bagi pasien hemodialysis, agar selain dengan hemodialysis, ada faktor internal dari pasien yang dapat dijadikan sebagai motivasi untuk sembuh dari penyakit.   Kata Kunci: Logoterapi, kualitas hidup   IMPROVE THE QUALITY OF LIFE OF PATIENTS WITH RENAL FAILURE WHO UNDERWENT HEMODIALYSIS   ABSTRACT Logotherapy is a therapy to discover the positive meaning behind an unexpected event. Logotherapy is carried out individually or in groups in the form of counseling and oriented to the search for the meaning of individual life. This study aims to improve the quality of life of patients with renal failure who underwent hemodialysis. This research was conducted by using pre-experiment with pre-post test study. The sampling technique was done by the convenience sampling. The number of patients undergoing hemodialysis as many as 46 respondents. Data analysis was done by using test t test dependent. The result showed that from 46 respondents got the mean of quality of life of patients who had hemodialysis 60.22 with lowest score 55 and highest score 69. Whereas from 46 respondents got the mean score of life quality of patients who had hemodialysis 88.72 with score the lowest score 79 and the highest score 103. The result of statistical test with t test dependent is known there is influence of logoterapi to the ability of meaningful life on client who undergo hemodialysis at Semarang Regency hospitals (p value: 0.0001). Advice on the need to improve the nurse's ability to provide health services, including the provision or guidance of the discovery of the meaning of life for hemodialysis patients, in addition to hemodialysis, there are internal factors of the patient that can be used as a motivation to recover from illness.   Keywords: Logotherapy, quality of life, kidney failure.  


Renal Failure ◽  
2007 ◽  
Vol 29 (7) ◽  
pp. 823-828 ◽  
Author(s):  
Beril Akman ◽  
Ayse Bilgic ◽  
Gulsah Sasak ◽  
Siren Sezer ◽  
Atilla Sezgin ◽  
...  

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Hossein Estiri ◽  
Zachary H. Strasser ◽  
Jeffy G. Klann ◽  
Pourandokht Naseri ◽  
Kavishwar B. Wagholikar ◽  
...  

AbstractThis study aims to predict death after COVID-19 using only the past medical information routinely collected in electronic health records (EHRs) and to understand the differences in risk factors across age groups. Combining computational methods and clinical expertise, we curated clusters that represent 46 clinical conditions as potential risk factors for death after a COVID-19 infection. We trained age-stratified generalized linear models (GLMs) with component-wise gradient boosting to predict the probability of death based on what we know from the patients before they contracted the virus. Despite only relying on previously documented demographics and comorbidities, our models demonstrated similar performance to other prognostic models that require an assortment of symptoms, laboratory values, and images at the time of diagnosis or during the course of the illness. In general, we found age as the most important predictor of mortality in COVID-19 patients. A history of pneumonia, which is rarely asked in typical epidemiology studies, was one of the most important risk factors for predicting COVID-19 mortality. A history of diabetes with complications and cancer (breast and prostate) were notable risk factors for patients between the ages of 45 and 65 years. In patients aged 65–85 years, diseases that affect the pulmonary system, including interstitial lung disease, chronic obstructive pulmonary disease, lung cancer, and a smoking history, were important for predicting mortality. The ability to compute precise individual-level risk scores exclusively based on the EHR is crucial for effectively allocating and distributing resources, such as prioritizing vaccination among the general population.


2018 ◽  
Vol 1 (2) ◽  
pp. 139-153
Author(s):  
Fitri Rahayu ◽  
Topan Fernandoz ◽  
Rafika Ramlis

The aim of this study was to determine whether there is a relationship between hemodialysis frequency stress levels in patients with chronic renal failure undergoing hemodialysis  at hemodialysis installation  of dr. M. Yunus hospital Bengkulu City 2016. The study design used was a descriptive analytic method to explain each variable studied. The results showed that there was a significant relationship between the frequency of hemodialysis with the level of stress in patients with chronic renal failure, almost all respondents often undergo hemodialysis in hemodialysis installation in dr. M.Yunus hospital in Bengkulu city, of a total of 67 respondents almost half of respondents suffered moderate stress levels and no significant association between HD frequency with the stress levels of patients with CKD in Haemodialysis installation with p value 0.041 smaller than 0.05. The results of this study are expected to add insight and knowledge about the disease of CKD, and and is expected to continue this research in the context of a deeper and broader variables. Keywords: Frequency, Hemodialysis, Stress Levels.  


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