scholarly journals Diabetic Nephropathy: a Concise Assessment of the Causes, Risk Factors and Implications in Diabetic Patients

2018 ◽  
Vol 69 (11) ◽  
pp. 3118-3121 ◽  
Author(s):  
Andra Elena Balcangiu Stroescu ◽  
Maria Daniela Tanasescu ◽  
Alexandru Diaconescu ◽  
Laura Raducu ◽  
Daniela Gabriela Balan ◽  
...  

Due to the increasing number of patients in recent years, diabetes represents one of the major medical concerns. This is owed to the meaningful impact this disease has on patients� quality of life and secondary to its complications over patient survival. Diabetic nephropathy epitomises one of the complications in these patients and plays a significant role in establishing their life expectancy.

Author(s):  
Christa Kingston ◽  
Aravindan J. ◽  
Srikumar Walsalam

Background: Diabetic neuropathy is one among the most common complication in diabetes mellitus. Diabetic peripheral neuropathy hinders the quality of life causing morbidity and mortality. The purpose of this study was to find the risk factors associated with diabetic neuropathy.Methods: This case control study involved 100 diabetic patients attending the Dohnavur fellowship hospital, Dohnavur from October 2019 to March 2020. Sociodemographic profile and diabetic characteristics of the study group were obtained and analysed. Diagnosis of Diabetic Neuropathy was done by using the diagnostic method proposed by American Diabetic Association.Results: Of the total study population with mean age 59.43 years, 63% had family history of diabetes. Almost 70% had poor diabetic control. Statistically significant relationships were found between neuropathy and duration of diabetes, glycaemic control, history of hypertension, monofilament test and pinprick sensation.Conclusions: In this study, glycemic control, dyslipidemia and hypertension were modifiable risk factors for diabetic neuropathy. Early interventional programs to sensitize diabetics on these factors could improve the quality of life of Diabetic patients. 


2021 ◽  
Vol 23 (4) ◽  
pp. 268-294
Author(s):  
Amina Badawy Othman ◽  
Seham Abd Elalem ◽  
Dalia Elsherbini ◽  
Neima Riad

2014 ◽  
Vol 8 (3) ◽  
pp. 371-379 ◽  
Author(s):  
Attasit Srisubat ◽  
Jiruth Sriratanaban ◽  
Sureerat Ngamkiatphaisan ◽  
Kriang Tungsanga

Abstract Background: Diabetes is a leading cause of end stage renal disease (ESRD), which impacts on treatment costs and patients’ quality of life. Microalbuminuria screening in patients with diabetes as an early intervention is beneficial in slowing the progression of diabetic nephropathy. Objectives: We aimed to assess the cost-effectiveness of annual microalbuminuria screening in type 2 diabetic patients. Methods: We compared screening by urine dipsticks with a “do nothing” scenario. To replicate the natural history of diabetic nephropathy, a Markov model based on a simulated cohort of 10,000 45-year-old normotensive diabetic patients was utilized. We calculated the cost and quality of life gathered from a cross-sectional survey. The costs of dialysis were derived from The National Health Security Office (NHSO). We also calculated the incremental cost-effectiveness ratio (ICER) for lifetime with a future discount rate of 3%. Results: The ICER was 3,035 THB per quality-adjusted life year (QALY) gained. One-way and probabilistic sensitivity analyses showed that all ICERs were less than the Thai Gross Domestic Product (GDP) per capita (150,000 THB in 2011) based on World Health Organization’s suggested criteria. Conclusions: Annual microalbuminuria screening using urine dipsticks in type 2 diabetic patients is very costeffective in Thailand based on World Health Organization’s recommendations. This finding has corroborated the benefit of this screening in the public health benefit package.


2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Jnadi M. Madkhali ◽  
Ammar A. Hakami ◽  
Ali H. Dallak ◽  
Ramzi M. Hakami ◽  
Abdullah A. Yatimi ◽  
...  

Context. Patients with diabetes mellitus (DM) have a poorer quality of life when compared with patients without DM. In fact, one in every five diabetic patients suffers from comorbid depression, which can lead to poor management, poor compliance with treatment, and low quality of life. Therefore, we assessed the prevalence of depression and identified its associated factors among diabetic patients at Jazan Province, KSA. Methods and Materials. A cross-sectional study was conducted among 500 diabetic patients attending a diabetic center in addition to four primary healthcare centers. We used a simple Arabic translation of the Beck Depression Inventory (BDI II) tool to evaluate the depression level among the subjects. We also evaluated the frequencies of certain sociodemographic characteristics and clinical information. Moreover, we performed univariate and multivariate analyses to identify the potential risk factors using adjusted odds ratios (AORs). Results. The prevalence of depression among DM patients was 20.6%. The majority of patients showed no depression (N = 285, 59.4%), one-fifth had mild depression (N = 96, 20.0%), some (N = 55, 11.4%) had moderate depression, and some had severe depression (N = 44, 9.2%). Depression was significantly more prevalent among uneducated patients (N = 27, 31.8%) (X2 = 17.627, P = 0.001) and patients with low monthly income (< 2500 SR/month) (N = 33, 22.8%) (X2 = 9.920, P = 0.019). Hypertension (AOR = 2.531, 95% CI [1.454, 4.406]) and ischemic heart diseases (AOR = 3.892, 95% CI [1.995, 7.593]) were considered as risk factors for depression among diabetic patients. Conclusions. Almost one in every five patients with DM is affected by depression coexisting with cardiovascular diseases. Therefore, screening for psychological problems, proper treatment, and educating patients with diabetes about DM self-management should be routine components of DM care.


2020 ◽  
pp. 112067212091269
Author(s):  
Mohammed Ali Abu Ameerh ◽  
Ghada Ismail Hamad

Objectives: To investigate the prevalence of depressive symptoms among diabetic patients suffering from retinopathy, and to identify crucial risk factors that affect patients’ quality of life and whether social support mediates the relationship between retinopathy and depression. Methods: The sample comprises 155 participants with diabetic retinopathy recruited from the Jordan University Hospital during the year 2017. Arabic versions of all study tools were employed as follows: the Beck Depression Inventory; the short form of the health survey; the Berlin social support scale; ophthalmic examinations; patients’ records; and a demographic questionnaire. Analyses: Descriptive statistics, the Pearson correlation, linear regression using SPSS, and mediation analysis using the Sobel test were applied. In addition, the odds ratio analysis and qualitative analyses for the open-ended questions were included. Results: In general, 13 (8.9%) of our patients did not manifest any symptoms of depression while 42 (27.1%) had a mild mood disturbance, 26 (16.8%) were on the borderline of clinical depression, 47 (30.3%) had moderate depression, 22 (14.2%) with severe depression, and 5 (3.2%) had extreme depression. The results indicate a nonsignificant positive correlation between social support and health-related quality of life and a nonsignificant positive relationship between retinopathy severity and depression. Meanwhile, our results revealed a significant negative relationship between depression and social support and a nonsignificant negative relationship between retinopathy severity and social support. Conclusion: Our findings suggest that diabetic patients with retinopathy have a higher risk of developing depression. Hence, psychological interventions are highly needed to meet the mental health needs of these patients.


2014 ◽  
Vol 28 (1) ◽  
pp. 99 ◽  
Author(s):  
Duarte Pereira ◽  
Elisabete Ramos ◽  
Jaime Branco

<p>Osteoarthritis is nowadays one of the most frequent chronic diseases and, with the increase in life expectancy, both its prevalence and incidence is expected to rise. This condition is progressive and leads to functional decline and loss in quality of life, with important health care and society costs. A review of relevant and recent literature on osteoarthritis was performed in PubMed. The purpose of this study is to understand important aspects about osteoarthritis estimates, burden of disease, pathophysiology, risk factors, diagnosis<br />and treatment.<br /><strong>Keywords:</strong> Osteoarthritis/diagnosis; Osteoarthritis/epidemiology; Osteoarthritis/physiopathology; Osteoarthritis/therapy; Portugal; Risk Factors.</p>


1999 ◽  
Vol 19 (2_suppl) ◽  
pp. 242-247 ◽  
Author(s):  
Theofanis Apostolou ◽  
Ram Gokal

Oiabetes mellitus is the commonest cause of end-stage renal failure and is associated with considerable morbidity. Neuropathy is one of the most serious complications of diabetes, linked to the incidence of nephropathy and retinopathy. The prevalence of neuropathy increases with age and duration of diabetes. Peripheral sensorimotor neuropathy is the main manifestation of neurological dam -age in diabetes, while autonomic neuropathy, a devastating complication, is also present in a large number of patients with long-term diabetes. Clinical features of autonomic neuropathy are mainly cardiovascular disorders and abnormal visceral function. One of the most important sequelae of neuropathy is the development of the insensitive foot at risk of ulceration, deformation, Charcot neuroarthropathy, and amputation. Prevention, education, and identification of the at-risk patient are the key elements in managing these severe complications. Oialysis, and mainly peritoneal dialysis, still remains the main renal replacement therapy for end-stage renal disease (ESRO) diabetic patients. It is obvious from many studies that diabetes and its complications are major risk factors associated with poorer survival rates, increased morbidity, and decreased quality of life. Few, if any, data are available specifically evaluating quality of life in continuous ambulatory peritoneal dialysis (CAPO) diabetic patients. Fewer data are available estimating the impact of neuropathy on the quality of life of such patients. Specific studies must be carried out to further investigate quality-of-life issues and neuropathy in this vulnerable group of patients.


2014 ◽  
Vol 17 (4) ◽  
pp. 16-24
Author(s):  
Nadezhda Viktorovna Maximova ◽  
Maria Vadimovna Amosova ◽  
Evdokiya Sergeevna Tsvetkova ◽  
Natalya Alexandrovna Chubrova ◽  
Galina Afanas'evna Mel’nichenko

Adhesive capsulitis (АС) has an incidence of 20% in diabetic patients. The tightening of the shoulder capsule ("freezing") can cause gradually increasing limitation in active and passive range of motion (ROM) of shoulder. Consequences of the increasing limitations are reduced quality of life and patient disability. It is thought that AC is a self-limiting disorder that resolves in 1?2.5 years in most cases. However, new clinical data indicate both long-term persistent pain and residual loss of motion in 10% of patients without diabetes and in 85% of patients with diabetes. In this review, we summarize the results from different clinical trials in which risk factors and pathogenesis of AC in diabetic patients as well as the diagnosis and efficacy of various methods for the treatment of AC were examined.


2021 ◽  
Vol 5 (4) ◽  
pp. 17-21
Author(s):  
Yuting Liu

Diabetes is a chronic disease recognized by the World Health Organization, which is harmful to human life and health. With the improvement of people’s quality of life, people’s diet structure has changed greatly, and the primary “three high” prevalence rate has risen sharply. The main reason for the impaired life expectancy of a large number of diabetic patients is the threat of a series of cardiovascular complications. According to statistics, the risk of cardiovascular disease in diabetic patients are 2-4 times higher than that in non-diabetic patients. More than 80% of patients with type 2 diabetes die of cardiovascular disease every year, and 75% of them have ischemic heart disease [1]. All kinds of data show that diabetes mellitus complicated with cardiovascular diseases have become a worldwide public health problem. We must try our best to find a cure mechanism and give patients a healthy life. In order to effectively curb the threat of diabetes complicated with cardiovascular disease patients, we should strengthen the research in this field. Through the analysis of the risk factors of diabetic cardiovascular disease, we can let the majority of medical workers understand the superficial and potential risk factors, to formulate scientific and reasonable treatment plan, for further improving the quality of life of patients. In the following, the author first introduces the basic situation of diabetes and cardiovascular complications, then introduces the main risk factors of diabetic cardiovascular disease one by one, hoping that this study can help to improve the cure rate of diabetes complicated with cardiovascular disease.


Sign in / Sign up

Export Citation Format

Share Document