In vitro Behaviour of Alumina-Hydroxiapatite Composites Coatings

2018 ◽  
Vol 69 (6) ◽  
pp. 1416-1418
Author(s):  
Alexandru Szabo ◽  
Ilare Bordeasu ◽  
Ion Dragos Utu ◽  
Ion Mitelea
Keyword(s):  
Pure Titanium ◽  
Titanium Substrate ◽  
High Strength ◽  
Biological Properties ◽  
Commercially Pure Titanium ◽  
Hvof Spraying ◽  
Before And After ◽  
Sbf Solution ◽  
Oxygen Fuel

Hydroxyapatite (HA) is a very common material used for biomedical applications. Usually, in order to improve its poor mechanical properties is combined or coated with other high-strength materials.The present paper reports the manufacturing and the biocompatibility behaviour of two different biocomposite coatings consisting of alumina (Al2O3) and hydroxyapatite (HA) using the high velocity oxygen fuel (HVOF) spraying method which were deposited onto the surface of a commercially pure titanium substrate. The biological properties of the Al2O3-HA materials were evaluated by in vitro studies. The morphology of the coatings before and after their immersing in the simulated body fluid (SBF) solution was characterized by scanning electron microscopy (SEM). The results showed an important germination of the biologic hydroxyapatite crystallite on the surface of both coatings.

Development and Characterization of Nano-TiO2/HA Composite Bioceramic Coating on Titanium Surface

2007 ◽  
Vol 336-338 ◽  
pp. 1802-1805 ◽  
Author(s):  
Gang He ◽  
Xia Deng ◽  
Yuan Kun Cen ◽  
Xiao Yu Li ◽  
En Luo ◽  
...  
Keyword(s):  
Surface Morphology ◽  
Sol Gel ◽  
Pure Titanium ◽  
Titanium Substrate ◽  
Commercially Pure Titanium ◽  
Nano Tio2 ◽  
Tio2 Anatase ◽  
Crystallization Surface

This research is aimed at the development and characterization of a novel bioceramic coating on the surface of pure titanium. Nano-TiO2/HA composite bioceramic coating was designed and developed on the surfaces of pure titanium discs by sol-gel route. The TiO2 anatase bioceramic coating was employed as the inner layer, which could adhere tightly to the titanium substrate. The porous HA bioceramic coating was employed as the outer layer, which has higher solubility and better short term bioactivity. Conventional HA coatings and commercially pure titanium (cpTi) were taken as control. XRD and SEM were employed to characterize the crystallization, surface morphology and thickness of the coatings. The bioactivities of the coatings were evaluated by the in vitro osteoblasts culture. Results show the nano-TiO2/HA composite bioceramic coating has good crystallization and homogeneous, nano-scale surface morphology. And it adheres tightly to the substrate. The in vitro osteoblasts culture exhibits satisfactory bioactivity.

scholarly journals Laser-Sustained Plasma (LSP) Nitriding of Titanium: A Review

Coatings ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 283 ◽  
Author(s):  
Amar M. Kamat ◽  
Stephen M. Copley ◽  
Albert E. Segall ◽  
Judith A. Todd
Keyword(s):  
Wear Resistance ◽  
Gas Flow ◽  
Pure Titanium ◽  
Titanium Substrate ◽  
Surface Hardness ◽  
Weight Ratio ◽  
High Strength ◽  
Nitrogen Plasma ◽  
Commercially Pure Titanium ◽  
Laser Nitriding

Titanium and its alloys possess several attractive properties that include a high strength-to-weight ratio, biocompatibility, and good corrosion resistance. However, due to their poor wear resistance, titanium components need to undergo surface hardening treatments before being used in applications involving high contact stresses. Laser nitriding is a thermochemical method of enhancing the surface hardness and wear resistance of titanium. This technique entails scanning the titanium substrate under a laser beam near its focal plane in the presence of nitrogen gas flow. At processing conditions characterized by low scan speeds, high laser powers, and small off-focal distances, a nitrogen plasma can be struck near the surface of the titanium substrate. When the substrate is removed, this plasma can be sustained indefinitely and away from any potentially interacting surfaces, by the laser power and a cascade ionization process. This paper presents a critical review of the literature pertaining to the laser nitriding of titanium in the presence of a laser-sustained plasma, with the ultimate objective of forming wide-area, deep, crack-free, wear-resistant nitrided cases on commercially pure titanium substrates.

scholarly journals Effect of Sintering and Concentration of Dymethylformamide on Surface Properties of Hydroxyapatite Coating on Titanium Substrate Fabricated by Electrophoretic Deposition

2020 ◽  
Vol 10 (2) ◽  
pp. 90
Author(s):  
Mochammad Dachyar Effendi ◽  
Razie Hanafi ◽  
Utari Pusparini ◽  
Sara Aisyah Syafira
Keyword(s):  
Surface Morphology ◽  
Electrophoretic Deposition ◽  
Pure Titanium ◽  
Titanium Substrate ◽  
Orthopaedic Implant ◽  
Commercially Pure Titanium ◽  
X Ray ◽  
Before And After ◽  
Grooved Surface ◽  
Cp Ti

Hydroxyapatite (HAp) coating on metallic implant was developed to increase bioactivity of orthopaedic implant. In this work, hydroxyapatite was successfully deposited on commercially pure titanium (CP-Ti) substrate by electrophoretic deposition (EPD). This work aims to determine the effect of dimethylformamide (DMF) as dispersant for EPD suspension followed by heat treatment, on the surface morphology of the HAp coating. HAp powder was suspended in an ethanol-DMF solution with the amount of DMF designed at 0, 5, 10, and 15% per 100 mL suspension. EPD was then performed successfully on all samples. After EPD, the specimens were sintered at 800 °C for 120 minutes in argon atmosphere. Surface morphology, composition, and phase of HAp coating before and after sintering were characterized by Scanning Electron Microscope, Fourier Transform Infrared Spectrometer, and X-ray Diffractometer. X-ray and IR spectra confirmed that sintering had a little effect on the chemical structure and the phase of the deposited HAp. The morphology of the surface is denser across all samples and shows distinguishable features as the amount of DMF in the system was increased. The 15% DMF sample exhibits the mostly grooved surface after sintering. Further analysis showed that sintering reduced the EPD-related shrinkage on the surface and enhanced the size of the pores. Microstructural indication referring to previous research suggested that this type of microscopic surface is very sought after in promoting a good biological interaction between the implant and the host. Further testing must be done to confirm the effect of DMF-modified structure in living tissue.

In vitro comparative analysis of the fit of gold alloy or commercially pure titanium implant-supported prostheses before and after electroerosion

2004 ◽  
Vol 92 (2) ◽  
pp. 132-138 ◽  
Author(s):  
Ivete Aparecida de Mattias Sartori ◽  
Ricardo Faria Ribeiro ◽  
Carlos Eduardo Francischone ◽  
Maria da Gloria Chiarello de Mattos
Keyword(s):  
Comparative Analysis ◽  
Gold Alloy ◽  
Pure Titanium ◽  
Titanium Implant ◽  
Commercially Pure Titanium ◽  
Commercially Pure ◽  
Before And After

Sliding Wear Behavior of Remelted Al2O3-TiO2 Plasma Sprayed Coatings on Titanium

2016 ◽  
Vol 254 ◽  
pp. 231-236 ◽  
Author(s):  
Ion Dragoş Uţu ◽  
Gabriela Marginean ◽  
Iosif Hulka ◽  
Viorel Aurel Şerban
Keyword(s):  
Sliding Wear ◽  
Wear Behavior ◽  
Pure Titanium ◽  
Titanium Substrate ◽  
Atmospheric Plasma ◽  
Wear Properties ◽  
Before And After ◽  
Sprayed Coating ◽  
Pin On Disk ◽  
Sprayed Coatings

Microstructure and wear properties of the Al2O3-13.wt% TiO2 thermally sprayed coatings before and after remelting were investigated in this study. The coatings were deposited on a pure titanium substrate using the atmospheric plasma spraying (APS) process. The as-sprayed coatings were electron beam (EB) modified in order to improve their compactness and bonding strength.The effect of EB remelting on the microstructure, phase constituents and wear properties was investigated using scanning electron microscopy (SEM), X-Ray diffraction technique and hardness measurements. The sliding wear behavior was tested using a pin on disk method.The results showed that the remelting process had a positive effect removing the lamellar defect of the as-sprayed coating and improving the compactness, hardness and wear behavior.

Solidification in Laser Cladding of a Ti-Si Graded Coating on Pure Titanium Substrate

2013 ◽  
Vol 739 ◽  
pp. 196-200 ◽  
Author(s):  
T.M. Yue ◽  
K.J. Huang ◽  
H. Xie
Keyword(s):  
Laser Cladding ◽  
Solid Solutions ◽  
Silicon Content ◽  
Pure Titanium ◽  
Titanium Substrate ◽  
Eutectic Growth ◽  
Commercially Pure Titanium ◽  
Commercially Pure ◽  
Graded Coating

A three-layer Ti-Si graded coating was fabricated on a commercially pure titanium substrate by laser cladding with Ti-5.8 at%Si, Ti-9.0 at%Si and Ti-13.5 at%Si mixed powders. The microstructure of the three layers comprised Ti-Si solid solutions (Ti) and the Ti5Si3 compound. As the silicon content was increased, the microstructure along the direction of deposition underwent a series of changes, including replacement of the (Ti) phase by the primary Ti5Si3 phase, and a change of the (Ti)/Ti5Si3 eutectic growth from lamellar to anomalous.

Comparative Evaluation of the Bioactive Behavior of HA and ZrO2 Reinforced Coatings

2011 ◽  
Vol 493-494 ◽  
pp. 447-452
Author(s):  
George Theodorou ◽  
Ourania Menti Goudouri ◽  
Lambrini Papadopoulou ◽  
Nikolaos Kantiranis ◽  
Subramaniam Yugeswaran ◽  
...  
Keyword(s):  
Steel Substrate ◽  
In Vitro Bioactivity ◽  
Biological Fixation ◽  
Metal Implants ◽  
Ha Coating ◽  
Biological Responses ◽  
Before And After ◽  
Sbf Solution ◽  
Plasma Sprayed

The clinical use of plasma-sprayed hydroxyapatite (HA) coatings on metal implants has been widely investigated as the HA coating can achieve the firm and direct biological fixation with the surrounding bone tissue. It is shown in previous studies that the mechanical properties of HA coatings are improved by the addition of ZrO2 particles during the deposition of the coating on the substrate. Subsequently, the cohesive and adhesive strengths of plasma-sprayed hydroxyapatite (HA) coatings were strengthened by the ZrO2 particles addition as a reinforcing agent in the HA coating (HA+ZrO2 composite coating). The aim of the present work is to investigate and evaluate the in vitro bioactivity assessment of HA and HA/ZrO2 coatings, on stainless steel substrate, soaked in c-SBF, in order to study and compare their biological responses. The coatings were produced using vapor plasma spraying (VPS). The characterization of the surface of the coatings before and after soaking in SBF solution was performed using Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM) and X-ray Diffraction analysis (XRD). All samples were smoothed before insertion in the medium and the in vitro bioactivity of all coating samples was tested in conventional Simulated Body Fluid (c-SBF) solution for various immersion times.

scholarly journals In vitro bioactivity of Polyurethane/85S Bioglass composite scaffolds

2013 ◽  
Vol 11 (9) ◽  
pp. 1439-1446 ◽  
Author(s):  
Lachezar Radev ◽  
Darina Zheleva ◽  
Irena Michailova
Keyword(s):  
Sol Gel ◽  
Spherical Particles ◽  
Polymerization Reaction ◽  
In Vitro Test ◽  
In Vitro Bioactivity ◽  
Before And After ◽  
Vitro Test ◽  
Sbf Solution ◽  
Static Conditions

AbstractIn the present work Polyurethane (PU)/Bioglass (BG) composite materials were synthesized with different content of BG (10 and 20 mol.%) as filler. The 85S Bioglass was synthesized via polystep sol-gel method. The chemical composition of BG is 85SiO2-10CaO-5P2O5 (wt.%). The synthesis of PU was carried out by a two-step polyaddition reaction. The 85S BG was added in situ during the polymerization reaction. In vitro bioactivity of the prepared composites was examined in the presence of 1.5 SBF for 7 days in static conditions. The structure of synthesized PU/BG composites before and after in vitro test was determined by XRD, FTIR and SEM. XRD of the samples before in vitro test proved that the phase of γCa2P2O7 in the PU/20BG is visible. FTIR revealed the presence of urethane bond between OH-(from BG) and NCO groups (from PU). Based on FTIR results after in vitro test in 1.5 SBF solutions, A/B-carbonate containing hydroxyapatite (CO3HA) was formed. XRD proved that HA was formed on the surface of the samples, but Ca2P2O7 does not undergo any changes in the 1.5 SBF solution. SEM depicted the nano-HA agglomerated in spherical particles after immersion in 1.5 SBF for 7 days.

scholarly journals Fabrication of High-Strength and Porous Hybrid Scaffolds Based on Nano-Hydroxyapatite and Human-Like Collagen for Bone Tissue Regeneration

Polymers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 61 ◽  
Author(s):  
Yannan Liu ◽  
Juan Gu ◽  
Daidi Fan
Keyword(s):  
Mechanical Properties ◽  
Enzymatic Hydrolysis ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Repair ◽  
Three Dimensional ◽  
High Strength ◽  
Biological Properties ◽  
Bone Tissue Regeneration

A novel, three-dimensional, porous, human-like collagen (HLC)/nano-hydroxyapatite (n-HA) scaffold cross-linked by 1,2,7,8-diepoxyoctane (DEO) was successfully fabricated, which showed excellent mechanical and superior biological properties for bone tissue regeneration in this study. The physicochemical characterizations of different n-HA/HLC/DEO (nHD) scaffolds were investigated by determining the morphology, compression stress, elastic modulus, Young’s modulus and enzymatic hydrolysis behavior in vitro. The results demonstrated that nHD-2 and nHD-3 scaffolds showed superior mechanical properties and resistance to enzymatic hydrolysis compared to nHD-1 scaffolds. The cell viability, live cell staining and cell adhesion analysis results demonstrated that nHD-2 scaffolds exhibited low cytotoxicity and excellent cytocompatibility compared with nHD-1 and nHD-3 scaffolds. Furthermore, subcutaneous injections of nHD-2 scaffolds in rabbits produced superior anti-biodegradation effects and histocompatibility compared with injections of nHD-1 and nHD-3 scaffolds after 1, 2 and 4 weeks. In addition, the repair of bone defects in rabbits demonstrated that nHD-2 scaffolds presented an improved ability for guided bone regeneration and reconstruction compared to commercially available bone scaffold composite hydroxyapatite/collagen (HC). Collectively, the results show that nHD-2 scaffolds show promise for application in bone tissue engineering due to their excellent mechanical properties, anti-biodegradation, anti-biodegradation, biocompatibility and bone repair effects.

Sign in / Sign up

Export Citation Format

Share Document