Severity of Psoriasis Associated with Metabolic Syndrome

2019 ◽  
Vol 70 (6) ◽  
pp. 2072-2079
Author(s):  
Ana Maria Alexandra Stanescu ◽  
Constantin Stefani ◽  
Ioana Veronica Grajdeanu ◽  
Bogdan Serban ◽  
Gheorghe Ciobanu ◽  
...  

Although extensively studied, psoriasis still has negative consequences and is associated with multiple comorbidities, including metabolic syndrome. The severity of psoriasis seems to influence the occurrence of diagnostic criteria for metabolic syndrome. 208 patients diagnosed with psoriasis were identified, who were divided into lots depending on the severity of psoriasis, but also to the presence or absence of metabolic syndrome. Interpretation of statistical data was done with SPSS V21 (Statistical Package for Social Science) and MEDCALC (Statistical Software). The coexistence of severe psoriasis with metabolic syndrome increases the risk of developing cardiovascular diseases by 2.97 or greater, with a confidence interval of [1.60, 5.51], than that of patients with severe psoriasis who have no metabolic syndrome. The hypothesis was statistically confirmed by p = 0.003. Analyzing the total group with psoriasis by severity, we found the following distribution: from the total number of 208 patients, 39 (18.8%) had severe psoriasis, 83 (39.9%) moderate psoriasis and 86 (41.3%) mild psoriasis. The higher incidence of metabolic syndrome in patients with psoriasis is evidenced by the Pearson Chi-Square test, where p [0.001. The association of metabolic syndrome in patients with psoriasis is evident. The more severe the psoriasis, the more likely it is to develop metabolic syndrome.

Author(s):  
Matthew W Parker ◽  
Diana Sobieraj ◽  
Mary Beth Farrell ◽  
Craig I Coleman

Background: Little has been published on the practice of echocardiography (echo) in the United States. We used the Intersocietal Accreditation Commission-Echocardiography (IAC-Echo) applications database to describe the personnel in echo laboratories seeking accreditation. Methods: We used de-identified data provided on IAC-Echo applications to characterize facilities by hospital association, census region, annual volume, number of sites, previous accreditation, and numbers of physicians and sonographers as well as National Board of Echocardiography (NBE) testamur status of physicians and registered credential status of sonographers. We categorized Medical Directors by board certification in cardiovascular diseases, internal medicine, other specialty, or none. Medical Director echo training could be formal Level 2 or 3 or experiential by ≥3 years of practice. Frequencies, means, and medians were compared between groups using the chi-square test, t-test, or Mann Whitney test, respectively. Results: From 2011 to 2013, 1926 echo labs representing 10618 physicians and 6870 sonographers applied for IAC-Echo accreditation or re-accreditation. The majority of medical directors were board certified in cardiovascular diseases and 34.1% of medical directors and 27.2% of staff physicians held NBE testamur status; 79.5% of sonographers held registered credentials. Most echo labs were in the Northeast or South census regions, have an average of 1.75 sites, and are based outside of hospitals (Table). Compared to nonhospital echo labs, medical directors of hospital-based echo labs were more likely to be Level 3 trained (19.8% versus 30.8%, p<0.01) and be NBE testamurs (28.9% versus 45.6%, p<0.01). Markers of echo lab size, region, previous accreditation, and credentialed sonographers were associated with accreditation versus delay decisions; there was a trend toward accreditation among facilities with NBE medical directors. Conclusion: Among facilities seeking IAC-Echo accreditation, the minority of echo physicians hold NBE testamur status. Hospital and nonhospital facilities are different in the credentials of their personnel.


2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Eunsu Jang ◽  
Younghwa Baek ◽  
Kihyun Park ◽  
Siwoo Lee

The Sasang Constitutional Medicine is a traditional Korean customized medicine that classifies people into four types: Tae-eumin (TE), Soyangin (SY), Soeumin (SE), and Taeyangin. The aim of this study was to show whether the Sasang Constitution (SC) could be an independent risk factor for the metabolic syndrome (MS). Totally, 3,334 subjects from 24 Korean medicine clinics participated in this study. A one-way ANOVA for the continuous variables and a chi-square test for the prevalence of MS were conducted. A logistic regression was conducted to calculate the propensity score and the odds ratios (ORs). The prevalence for MS in TE, SY, and SE was 50.6%, 30.9%, and 17.7% (P<0.001) before matching, and 36.7%, 28.6% and 28.2% (P=0.042) after matching, respectively. The TE was associated with an increased OR for MS compared with the SE and SY in both crude (OR 4.773, 95% CI 3.889–5.859, and OR 2.292, 95% CI 1.942–2.704, resp.) and matched groups (OR 1.476, 95% CI 1.043–2.089, and OR 1.452, 95% CI 1.026–2.053, resp.). This study reveals that the SC, especially the TE type, could be considered as a risk element for MS even in people with otherwise similar physical characteristics.


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Inka Miñambres ◽  
Joan Sánchez-Hernández ◽  
Jose Luis Sánchez-Quesada ◽  
Jose Rodríguez ◽  
Alberto de Leiva ◽  
...  

Background. It remains uncertain whether the metabolic syndrome (MS) or insulin resistance contribute to the association between vitamin D deficiency and obesity. Methods. We conducted a cross-sectional survey of 343 subjects who were overweight or obese. We analyzed anthropometric data and the presence or absence of MS. Additionally, we determined 25-hydroxyvitamin D (25OHD) and insulin concentrations, and the HOMA index was calculated. Chi-square test,Mann-Whitney U test, Student's t-tests,and logistic regression analysis were used. Results. The mean age of the patients was 42±11 years, and 65.9% were women. The mean BMI was 34.7±8.3 kg/m2 and 25(OH)D levels were 53.7±29.8 nmol/L. Forty-six patients (13.4%) had MS. Vitamin D status was associated with the degree of obesity, especially with a BMI > 40 kg/m2. Patients with MS had lower levels of 25(OH)D than patients without (43.3±29.0 versus 55.3±29.6 mmol/L, resp.), and the odds ratio for hypovitaminosis D was 2.7 (confidence interval (CI), 1.14–6.4) (P=.023) for patients with MS versus patients without MS, irrespective of the degree of obesity. Conclusions. Our data confirm the association between vitamin D and MS and suggest that this association is independent of the degree of obesity.


2017 ◽  
Vol 13 (1) ◽  
pp. 16-25 ◽  
Author(s):  
Gregory J Tierney ◽  
Karl Denvir ◽  
Garreth Farrell ◽  
Ciaran K Simms

Tackling is a major component of rugby union and effective attacking and defensive play are essential for game outcomes. In this study, a number of pre-contact, contact and post-contact tackle characteristics that had an influence on tackle gainline success for the ball carrier and tackler were identified using match video evidence from European Rugby Champions Cup games. A total of 122 front-on tackles and 111 side-on tackles were analysed. For each ball carrier and tackler characteristic, the Odds Ratio and 95% Confidence Interval were calculated based on a gainline success outcome. A Chi-Square and Phi and Cramer’s V calculation was also conducted. A Chi-Square test then identified any statistically significant differences (p < 0.05) for proficiency characteristics between playing position. For both the ball carrier and tackler, tackle characteristics that were indicative of strong and powerful tackle technique such as ‘explosiveness on contact’ and ‘leg drive on contact’ were effective for achieving the desired gainline outcome. Playing position had an influence on only two proficiency characteristics that were statistically significant for gainline success: ‘fending into contact’ for ball carriers and ‘straight back, centre of gravity forward of support base’ for tacklers.


10.21149/8470 ◽  
2018 ◽  
Vol 60 (4, jul-ago) ◽  
pp. 395 ◽  
Author(s):  
Abelardo Ávila-Curiel ◽  
Carlos Galindo-Gómez ◽  
Liliana Juárez-Martínez ◽  
Mario Luis Osorio-Victoria

 Objective. To estimate the prevalence of Metabolic Syndrome (MS), its components and its association with obesity and cardiovascular risk in school age children. Materials and methods. A cross-sectional study of 1,017 children from 6 to 12 years of age. Anthropometric information, blood pressure, glucose, insulin, cholesterol, HDLc, LDLc and triglycerides were collected. The presence of MS and its components were determined by criteria of Cook et. al. (2003), modified for children and adolescents. In the analysis, the children were grouped by aged group of 6 to 9 and 10 to 12 years. The association between MS, obesity and cardiovascular risk was estimated using Student’s t-test and Mann-Whitney U test, Chi-square test and logistic regression. Results. The MS was present with 54.6% in obese children. Obesity was the characteristic of greater association to suffer from MS with an OR=8.62 p<0.001. Conclusions. MS is high among children with obesity, and is mostly associated with insulin resistance and atherogenic risk. 


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 653-658
Author(s):  
Malavika Pradeep ◽  
Sridevi G ◽  
Kavitha S

Snoring is a loud sound that can be produced when air across the relaxed tissues of the throat. The causes of snoring include age, being overweight or out of shape, the way you are built, nasal and sinus problems, sleep posture, alcohol, smoking and medications. The present study was performed to find the association between the habit of snoring and health problems like hypertension, breathlessness, fatigue and chest pain among genders. A self-developed questionnaire to assess the snoring habits of the participants with their underlying health problems. The study was conducted on an online platform and the responses were collected. The datas were collected and analysed with the help of statistical software SPSS version 22 and chi-square test was used as a statistical analysis to find how snoring habit affects the participants based on the gender. The results revealed that male respondents who have the habit of snoring are more related to problems like breathlessness, hypertension, fatigue and chest pain compared to females. This result can be justified by the fact that females have strong hormonal support offered by estrogen that protects them from cardiovascular and respiratory disorders.


Author(s):  
Dhanalakshmi Kathirvel ◽  
Vaishnavi Dhandapani ◽  
Baskaran R. ◽  
Gladius Jennifer H.

<p class="abstract"><strong>Background:</strong> Psoriasis is a chronic inflammatory skin disease that affects 1-3% of the population. Recent studies have reported that psoriasis is associated with metabolic disorders, including obesity, dyslipidaemia and diabetes. The aim of the present study was to investigate the prevalence of metabolic syndrome (MS) in psoriasis and to evaluate the association with severity and duration of psoriasis</p><p class="abstract"><strong>Methods:</strong> This was a hospital based cross sectional study that involved 60 patients with psoriasis evaluated for MS. Statistical analysis was done by SPSS version 16.0 software. Percentages, mean, standard deviation, correlation, chi-square test, t test were calculated at 5% level of significance.<strong></strong></p><p class="abstract"><strong>Results:</strong> 20% of patients had MS which is comparable to the normal population. 60% of the patients in our study are obese which is directly correlating with MS. There is significant increase in MS as age (p =0.01), duration of psoriasis (p =0.03), BMI (p =0.0001), waist circumference (p =0.0001) increases.</p><p><strong>Conclusions:</strong> There is 20% association of psoriasis with MS. There is no gender predisposition and no association between the severity of psoriasis and metabolic syndrome. There is minimal relationship between the duration of psoriasis and metabolic syndrome. Obesity is the commonest factor related to psoriasis, diabetes and MS which should be taken care of by diet, exercise and lifestyle modification. </p>


2021 ◽  
Vol 129 ◽  
pp. 01018
Author(s):  
Renáta Machová ◽  
Enikő Korcsmáros ◽  
Monika Esseová ◽  
Roland Marča

Research background: The coronavirus has impacted the global economy as many businesses had to close due to the restrictions, and people’s spending and saving behaviour have changed. According to the negative consequences of the COVID-19, people reconsider their expenditures and rearrange their savings. To avoid the spread of infection, several employers switched to a home office where it was possible. As a result of working from home in numerous cases, monthly housing expenditures have increased. To prevent the spread of the disease, a great number of people tried not to appear in crowded places. Therefore, online shopping came to the fore. Purpose of the article: The main purpose of the article is to give a comprehensive picture of the relationship between the respondents’ job losses and their attitudes towards savings. Furthermore, the association was analysed, and its strength and direction were measured between the increased monthly housing expenditures and the reconsideration of shopping intentions. Moreover, the association was examined between the decreased spendings on commuting and the frequency of online shopping. Methods: The research was conducted among residents in two neighbouring V4 countries, Slovakia and Hungary. To analyse the formulated hypotheses, a nonparametric Pearson's chi-square test and Somers’ delta tests were used. Findings & Value added: Thanks to the results, it can be declared for both countries that there is an association between job losses due to the pandemic and saving behaviour. Based on Somers‘d test, there is a positive correlation between spending less on commuting and online shopping frequency and increased housing expenditures and shopping reconsideration between the respondents.


2021 ◽  
Vol 42 ◽  
Author(s):  
Christefany Régia Braz Costa ◽  
Elizabete Santos Melo ◽  
Marcela Antonini ◽  
Priscila Silva Pontes ◽  
Elucir Gir ◽  
...  

ABSTRACT Objective To identify overweight and obesity and as associated variables in people living with HIV. Method Cross-sectional, quantitative and analytical study, developed in specialized services in southeastern Brazil. Individual specifics were carried out from 2014 to 2016. Pearson's Chi-Square test, Logistic Regression and OddsRatio (OR) were used. Results Of the 340 respondents, 47.7% were overweight. The highest abdominal circumferences and lipid changes were predominantly among the highest body mass index (BMI). The greatest chances of obtaining BMI values>25 kg/m² were among men (OR: 1.87; 95% CI: 1.02-2.42), having metabolic syndrome (OR: 5.66; 95% CI: 3.26-9.83) and the undue (OR: 3.89; 95% CI: 2.17-7.00). However, having self-reported hypertension was configured as a protective factor (OR: 0.18; 95% CI: 0.08-0.44). Conclusion The frequency of obesity and overweight between PLHIV was high. There was an association of male gender, metabolic syndrome and smoking with weight gain. The presence of self-reported hypertension was considered a protective factor.


2012 ◽  
Vol 02 (04) ◽  
pp. 22-27
Author(s):  
Sathyanarayana Rao K. N. ◽  
Subbalakshmi N. K.

Abstract Introduction: It is imperative that efforts are to be made to recognize individuals with metabolic syndrome from different sets of population so that they may be identified for intensive risk factor management to reduce cardiovascular risk. We evaluated the incidence and associated factors of metabolic syndrome in inmates of old age homes. Methods: This study involved 189 subjects aged between 55-75 years of either sex housed in old age homes. In every subject waist circumference, blood pressure, fasting blood sugar and plasma lipids were measured. Ongoing treatments were taken into account. Patients with metabolic syndrome were identified using IDF-2005 definition. Data analysis was done by Chi -square test. p value less than 0.05 was taken as significant. Result: Metabolic syndrome was found in 57.67% of study subjects. Prevalence of metabolic syndrome was higher in 55 - 60 years age group (x2 =17.06, p < 0.01) and in females (x2 = 4.33, p < 0.05). Disease load of dyslipidemia, diabetes mellitus and hypertension was higher in metabolic syndrome group compared to non-metabolic syndrome group (x2 = 11.40, p<0.001; x2 = 47.90, p<0.0001; x2 = 4.72, p<0.05 respectively). In patients receiving treatment for diabetes and hypertension, frequency of subjects with hyperglycemia and high blood pressure was higher in metabolic syndrome group compared to non-metabolic syndrome group (x2 = 10.69, p<0.01; x2 = 4.46, p<0.05 respectively). Conclusion: In this population it is found that, 55-60 years age group and females are at greater risk for metabolic syndrome. Subjects with metabolic syndrome are resistant to anti-diabetic and antihypertensive treatment.


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