Identification of Sarcoptes scabiei by Clinical Examination and Follow-up Examination in Medan City, Indonesia

Background: Scabies is a disease caused by the mite Sarcoptes scabiei var. hominis. In Indonesia, scabies ranks third out of the 12 most common skin diseases. In terms of disease screening, direct visualization of dermatitis from mites and microscopy of skin scrapings is less sensitive. PCR and dermoscopy examinations have a high sensitivity value to Sarcoptes mites. Aims: This study aims to identify Sarcoptes scabiei mites between clinical symptoms and supporting examinations, namely PCR and dermoscopy methods. Methods: This research is a cross-sectional study, with descriptive analytics. The number of samples of 50 people who met the inclusion criteria was examined by microscopic examination, dermoscopy, and PCR. We state it to be positive if we found scabies mites or their eggs on microscopy, delta wing sign, or jet wet contrail on dermoscopy and there is a 135bp DNA band on PCR. Results: 50 samples diagnosed with scabies based on cardinal sign of scabies, gender were 80% male and 20% female with an average age of 14 years. Based on the location of the rash, the most rashes were between the fingers and toes, each 26% and the least on the head as much as 2%. Based examination tools, no Sarcoptes scabiei mites were found through microscopic and dermoscopic examination, while the PCR examination found 12 positive samples of scabies. Conclusion: PCR examination is very sensitive and specific even in very small quantities, with the fore primer SSUDF and the reverse primer SSUDR. Further research is needed to assess the sensitivity and specificity of dermoscopy and PCR in diagnosing scabies.

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Incidência de Interações Medicamentosas e Avaliação Clínica nos Pacientes de um Hospital Público Brasileiro

Ensaios e Ciência C Biológicas Agrárias e da Saúde ◽

10.17921/1415-6938.2020v24n3p202-210 ◽

2020 ◽

Vol 24 (3) ◽

pp. 202-210

Author(s):

Fabiana Cristina Furquim ◽

Cristina Eunice Okuyama ◽

Sandro Rostelato-Ferreira ◽

Carla Leticia Rivero-Wendt ◽

Helder Oliveira ◽

...

Keyword(s):

Clinical Symptoms ◽

Positive Association ◽

Signs And Symptoms ◽

Cross Sectional Study ◽

Documentary Evidence ◽

Potential Ddis ◽

Cross Sectional ◽

De Se ◽

Clinical Interactions

Interações droga-droga (IDDs) são responsáveis por problemas terapêuticos e as principais causas de reações adversas a medicamentos que levam a hospitalização. O objetivo do trabalho foi analisar a incidência de IDDs em pacientes admitidos em hospital público no Brasil, em 2015. Em um estudo transversal, 351pacientes foram selecionados com IDDs utilizando-se o banco de dados da Micromedex®, e as interações foram classificadas de acordo com a severidade e documentação. Os potenciais IDDs foram avaliados durante o acompanhamento farmacoterapêutico diário por anamnese farmacêutica e a análise dos exames laboratoriais foi realizada. Um total de 2.937 potenciais IDDs foram identificados e 28,42% deles tinham sinais e sintomas clínicos confirmados em 87 pacientes (29%). Entre os pacientes que apresentaram interações, 62,07% tinham mais que 60 anos. Neste grupo de idade, 61,27% de todos os sinais e sintomas clínicos observados foram também identificados, demonstrando uma associação positiva entre interações clínicas e idade. Além disso, uma correlação positiva entre o número de drogas prescritas e a ocorrência de sinais clínicos também foram observados. Muitos IDDs observados foram de severidade moderada e estavam relacionados a alterações das pressões arteriais e níveis glicêmicos. Este estudo demonstrou que IDDs estão diretamente relacionados a idade e número de drogas prescritas. E a grande frequência de IDDs com documentação fraca alertam para a necessidade de se analisar esse tipo de interação. Sendo assim, este estudo mostrou que potenciais IDDs e sinais e sintomas clínicos significantes em pacientes só reforçam a necessidade de se apoiar a farmácia clínica. Palavras-chave: Interação Droga-Droga (IDD). Pacientes Internados. Farmacoterapia, Poli Farmácia. Sinais e Sintomas. Abstract Drug-drug interactions (DDIs) are responsible for therapeutic problems and the main causes of adverse drug reactions that require hospitalization. The aim of this study was to analyze the incidence of DDIs in patients admitted in a Public Hospital in Brazil, in 2015. In a cross-sectional study, DDIs were screened in 351 patients, using Micromedex® database, that classify interactions according to severity and documentary evidence. Potential DDIs were assessed at the daily pharmacotherapeutic follow-up through pharmaceutical anamnesis and analysis of laboratory tests were performed. A total of 2,937 potential DDIs were identified and 28.42% of these had confirmed signs and symptoms clinical in 87 patients (29%). Among the patients that presented interactions, 62.07% were older than 60 years. In this age group, 61.27% of all signs and symptoms clinical observed in the study were also identified, demonstrating a positive association between the occurrence of clinical interactions and age. In addition, a positive correlation between the number of drugs prescribed and the occurrence of signs clinicals was also observed. Most DDIs observed were of moderate severity and were related to imbalance of blood pressure and glycemic levels. This study demonstrated that DDIs are directly related to the age and number of drugs prescribed. And the greater frequency of DDIs with fair documentary evidence alerts to the need to consider all the possible interactions. Thereafter, this study showed that potential DDIs and sign and clinical symptoms are significant in patients and reinforce the need to support Clinical Pharmacy. Keywords: Drug-Drug Interaction (DDI). Inpatients. Pharmacotherapy. Poly Pharmacy. Sign and Symptom.

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Task shifting in dermatology: Are nurses prepared and willing?

Our Dermatology Online ◽

10.7241/ourd.20221.4 ◽

2022 ◽

Vol 13 (1) ◽

pp. 22-27

Author(s):

Kavita Kavita ◽

Hitaishi Mehta ◽

Sandhya Ghai ◽

Aarti Garg ◽

Tarun Narang

Keyword(s):

Skin Diseases ◽

Task Shifting ◽

Cross Sectional Study ◽

Attitude Scale ◽

Cross Sectional ◽

Low Level ◽

High Knowledge ◽

Common Skin ◽

Level Of Knowledge ◽

Skin Conditions

Background: The high burden of skin diseases and the shortage of dermatologists are significant challenges in providing care to millions of people with skin diseases. Task shifting to nurses is a viable option for the delivery of dermatologic care in resource-poor settings. Satisfactory knowledge and a positive attitude are crucial for nurses to undertake the task of managing common skin diseases. This study aimed to investigate the knowledge of registered nurses and their attitude toward common skin conditions. Methods: In this descriptive, cross-sectional study, a total of 187 nurses were included from a nurses training institute by total enumeration sampling. A knowledge questionnaire and five-point Likert type-attitude scale were developed, validated, and employed to collect data. Written informed consent was obtained from the participants after approval from the institute ethics committee. Results: The mean of the knowledge scores were 10.7 ± 2.2. Nearly two thirds (62%) of the subjects demonstrated a low level of knowledge, while the remaining 38% showed a moderate level. There was no participant in the high-knowledge category. A majority of the nurses demonstrated a favorable attitude toward learning and undertaking the task of managing common skin conditions. Conclusion: We observed a low level of knowledge on diagnosing and managing common skin conditions. We recommend incorporating the relevant concepts of common skin conditions in the nursing curriculum with an emphasis on continuing education.

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Prevalence of Scabies and Impetigo in Patients of Different Age Groups in a Tertiary Level Hospital

The Journal of Sylhet Women’s Medical College ◽

10.47648/jswmc2021v11-07 ◽

2021 ◽

Vol 11 (Number 1) ◽

pp. 53-59

Author(s):

Parveen Afroz Chowdhury ◽

Tahur Abdullah Choudhury

Keyword(s):

Skin Diseases ◽

Clinical Symptoms ◽

Age Groups ◽

Lower Extremities ◽

Cross Sectional Study ◽

Upper Extremities ◽

Tertiary Level ◽

Cross Sectional ◽

The Individual ◽

Level Hospital

Background:Scabies and impetigo are found as two common skin diseases in developing countries. Scabies affects the whole family and has more impact on children and elderly people. The present study aims to provide an update on the prevalence and severity of scabies and impetigo in individual of different ages visited a tertiary level hospital. Methods: This observational cross sectional study includes a total of 3680 subjects complaining the clinical symptoms of scabies and impetigo. The patients were selected randomly and examined in outpatient department of Sylhet Women’s Medical Hospital during the period January, 2019 to October, 2020. Results:Scabies and impetigo were observed in 65.76% (n=2420) and 34.23% (n=1260) patients, respectively. However, the majority of scabies patients (65.74%, n=1591) were associated with impetigo. Both diseases were prevalent in males (57.02% in scabies and 57.14% in impetigo) compared to females (42.98% in scabies and 42.86% in impetigo). The highest prevalence of scabies (33.63%, n=814) and impetigo (40.88%, n=515) was observed among the individual aged 1-10 years. However, prevalence of the both diseases decreased gradually with the increase of age from 11-20 years to 51-60 years and above. Scabies lesions were more prevalent in upper extremities in patients aged 10-30 years and above. However, lower extremities in patients aged 10 years were found as the more prevalent sites for scabies lesions. On the other hand, impetigo lesions were the most prevalent in lower extremities followed by upper extremities in patients of all age groups. Although scabies and impetigo lesions were mostly mild (>50%) to moderate (~20-35%), lesions were severe in 15.58% of scabies patients aged 10-30 years and 22.89% of impetigo patients aged 10 years. Conclusions: Results reported herein supports the notion that scabies and impetigo are prevalent in school going children.

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Pattern of skin diseases in patients attended OPD of Dermatology and Venereology in a tertiary care teaching hospital in Bangladesh

Bangladesh Journal of Physiology and Pharmacology ◽

10.3329/bjpp.v29i1-2.20061 ◽

2014 ◽

Vol 29 (1-2) ◽

pp. 8-11

Author(s):

Abul Kalam Mohammad Yousuf ◽

Yasmin Joarder ◽

Ayasha Aktar ◽

Md. Nazmul Hoq ◽

Mushfika Rahman ◽

...

Keyword(s):

Skin Diseases ◽

Acne Vulgaris ◽

Tertiary Care ◽

Cross Sectional Study ◽

Personal Hygiene ◽

College Hospital ◽

Cross Sectional ◽

Economic Class ◽

Medical College ◽

Common Skin

Background: Skin problems are one of the most common health problems seen in the developing countries. Objective: To assess the pattern of skin diseases most commonly encountered in Dermatology & Venereology Outdoor Patient Department (OPD) of Northern International Medical college Hospital (NIMCH). Materials and Methods: This cross sectional study was carried out in the Dermatology & Venereology OPD of NIMCH, Dhanmondi, Dhaka, Bangladesh, during the period of January 2012 to December 2012. A total of 1169 patients (511male and 658 female) aged 10-44 years, attended in the OPD in which 969 patients (450 male and 519 female) were found to have dermatological problems. Data were analyzed by using SPSS soft-ware version 18. Results: The pattern of skin diseases was higher in females (53.6%) than in males (46.4%). The most common disorders seen in outpatient department is eczema (23.7%) followed by fungal infection (15.5%), scabies (13.4%) and acne vulgaris (11.9%). A remarkable part (41.4%) of the patients was illiterate. Majority of the patients (67.6%) belonged to poor socio-economic class. 61.4 % patients were residing in overcrowded homes and 53% patients were not maintained personal hygienic standards Conclusion: This study gives a fair picture of pattern of common skin diseases in urban Dhanmondi and its surrounding locality, Dhaka. From this study, it can be concluded that better health education, maintaining personal hygiene, improvement in the standard of living, proper case diagnosis and proper treatment may remain of importance in managing common skin diseases. http://dx.doi.org/10.3329/bjpp.v29i1-2.20061 Bangladesh J Physiol Pharmacol 2013; 29(1&2) : 8-11

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Increased Serum Levels of IFN-γ, IL-1β, and IL-6 in Patients with Alopecia Areata and Nonsegmental Vitiligo

Oxidative Medicine and Cellular Longevity ◽

10.1155/2020/5693572 ◽

2020 ◽

Vol 2020 ◽

pp. 1-5

Author(s):

Katarzyna Tomaszewska ◽

Magdalena Kozłowska ◽

Andrzej Kaszuba ◽

Aleksandra Lesiak ◽

Joanna Narbutt ◽

...

Keyword(s):

Oxidative Stress ◽

Alopecia Areata ◽

Skin Diseases ◽

Serum Levels ◽

Cross Sectional Study ◽

Cross Sectional ◽

Cytokine Levels ◽

Common Skin ◽

Registration Number ◽

Ifn Γ

Alopecia areata (AA) and vitiligo are both common skin diseases of autoimmune origin. Both alopecia areata and vitiligo have shown to be affected by oxidative stress. The present work is aimed at evaluating and comparing the serum proinflammatory cytokine levels in AA and nonsegmental vitiligo (NSV). A cross-sectional study was conducted of 33 patients with AA, 30 patients with NSV, and 30 healthy controls. Serum levels of interferon γ (IFN-γ), interleukin- (IL-) 1β, and IL-6 were determined quantitatively by ELISA method. Our analysis identified a signature of oxidative stress associated with AA and NSV, characterized by elevated levels of IFN-γ (AA: p=0.007283; NSV: p=0.038467), IL-1β (AA; NSV: p≤0.001), and IL-6 (AA; NSV: p≤0.001). IL-6 was also significantly increased in NSV patients in comparison with AA patients (p=0.004485). Our results supported the hypothesis that oxidative stress may play a significant role in promoting and amplifying the inflammatory process both in AA and vitiligo. The complex understanding of both disease etiopathogenesis involves interrelationships between oxidative stress and autoimmunity. The clinical study registration number is RNN/266/16/KE.

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Profil penyakit kulit pada pelajar sekolah asrama di Kabupaten Magelang, Jawa Tengah

Journal of Community Empowerment for Health ◽

10.22146/jcoemph.38312 ◽

2019 ◽

Vol 1 (2) ◽

pp. 79

Author(s):

Tuntas Rayinda ◽

Devi Artami Susetiati ◽

Sri Awalia Febriana

Keyword(s):

Skin Diseases ◽

Acne Vulgaris ◽

Boarding Schools ◽

Cross Sectional Study ◽

Pityriasis Versicolor ◽

Hormonal Changes ◽

Sectional Study ◽

Cross Sectional ◽

Different Types ◽

Common Skin

Individuals who live in boarding schools often experience various skin diseases, both infection and non-infectious because of exposure to various risk factors such as hormonal changes, poor hygiene and sanitation, and dense living quarters. To date, data on the prevalence of disease in adolescents in boarding schools are still very limited. This study is an observational cross-sectional study that aims to describe skin diseases that often occur in adolescents who live in boarding schools. Surveys and clinical examinations are carried out by dermatologist. Based on a survey of 1,250 students aged 10 - 16 years, 1,073 students (85.8%) had at least one skin disease. A total of 1,073 cases from 27 different types of skin diseases were found in these students. The five most common skin diseases are dermatophytosis, scabies, acne vulgaris, ecthyma, and pityriasis versicolor. Education, periodic surveys, mass treatment, and interventions to improve hygiene and living conditions are key to success in the management of skin diseases in students living in boarding schools.

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Hubungan Karakteristik Responden, Pengetahuan Dan Luas Ventilasi Dengan Kejadian Skabies Pada Santri Pondok Pesantren X Semarang

KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat ◽

10.24903/kujkm.v7i1.1167 ◽

2021 ◽

Vol 7 (1) ◽

pp. 150-158

Author(s):

Ana Novia Rahmawati ◽

Retno Hestiningsih ◽

Arie Wurjanto ◽

Martini Martini

Keyword(s):

Skin Diseases ◽

Sampling Technique ◽

Boarding School ◽

Sarcoptes Scabiei ◽

Cross Sectional Study ◽

P Value ◽

School Students ◽

Cross Sectional ◽

Level Of Education ◽

Gender Knowledge

Background: Scabies is a contagious skin disease caused by Sarcoptes scabiei. Scabies is still a neglected health problem in the world. In Indonesia, scabies ranks 3rd out of 12 of the most common skin diseases. Islamic boarding school students are generally prone to scabies because they live and sleep in the same place. Scabies can be caused by gender, level of education lack of knowledge and the extent of inadequate ventilation. Objectives: This study aims to analyze the relationship between gender, knowledge and extent of ventilation with the incidence of scabies at the Nurus Sunnah Islamic Boarding School Semarang. Research Metodes: This study is a quantitative study with an observational analytic approach and a cross-sectional study design. The sample in this study were 107 respondents with a purposive sampling technique. Data collection using google form and analyzed using chi square. Results: The results of this study indicate that there are 19.6% of respondents suffering from scabies. There was a sex relationship with the incidence of scabies (p-value = 0.001), there was no relationship between the level of education and the incidence of scabies (p-value = 0.557), there was a relationship between the level of knowledge and the incidence of scabies (p-value = 0.036), there was a relationship between the extent of ventilation. with the incidence of scabies (p-value = 0.023). Conclusion: There is a relationship between gender, knowledge and extent of ventilation with the incidence of scabies in students of the Nurus Sunnah Islamic Boarding School in Semarang in 2020. Keywords: scabies, knowledge, gender, area of ventilation, Islamic boarding school

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Prevalence of Common Skin Diseases and Their Associated Factors among Military Personnel in Korea: A Cross-sectional Study

Journal of Korean Medical Science ◽

10.3346/jkms.2012.27.10.1248 ◽

2012 ◽

Vol 27 (10) ◽

pp. 1248 ◽

Cited By ~ 20

Author(s):

Jung Min Bae ◽

Beomman Ha ◽

Hongsun Lee ◽

Chang Keun Park ◽

Hyun Joon Kim ◽

...

Keyword(s):

Military Personnel ◽

Associated Factors ◽

Skin Diseases ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Common Skin

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Pattern of skin diseases in patients attending OPD of selected upazilla health complex, Bangladesh

Z H Sikder Women’s Medical College Journal ◽

10.47648/zhswmcj.2020.v0202.01 ◽

2020 ◽

Vol 2 (Number 2) ◽

pp. 3-6

Author(s):

Chinmay Biswas ◽

Shila Rani Das

Keyword(s):

Skin Diseases ◽

Social Economic ◽

Parasitic Infection ◽

Cross Sectional Study ◽

Cross Sectional ◽

Different Types ◽

Common Skin ◽

Study Population ◽

Infectious Skin Diseases ◽

Diagnostic Importance

Skin diseases differ in different countries, and within various regions of a country depending on social, economic, racial and environmental factors. Many patients have reported various patterns of skin diseases in different countries. It was a descriptive type of cross sectional study conducted at outpatient department (OPD) of Dhamrai upazilla health complex to know the pattern of skin diseases during the period of June 2018 to December 2018. Total 2000 patients at any age and sex who attended in the OPD of the hospital with different types of skin disorders/diseases were selected as study population. Among the patients 27.05% were less than 10 years of age and 56.04% were female, 45.05% patients were illiterate, 57.03% had monthly family oncome more than Tk 15000 and 40.89% were housewife, 20.01% were students. The diagnosis was made on clinical basis as an expert dermatologist. Lab. investigations were restricted to the cases where they carried diagnostic importance. Majority (57%) were suffering from some infectious among them 33.02% had parasitic infection, 28.3% suffering from fungal infection, 20.1% bacterial infection and 43% from some non-infectious skin diseases among them 37.79% had eczema, 17.87% had papulosquamous disease, 14.25% had acne, 14.01% had urticaria, 8.7% had vitiligo. Infectious skin diseases were the most common skin disease seen in our study, followed by dermatological infections. The emerging challenges for dermatologists are to prevent and reduce these skin diseases.

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