Various Nanotube Scaffolds for Cell Proliferation

2009 ◽  
Vol 631-632 ◽  
pp. 181-186 ◽  
Author(s):  
Fumio Watari ◽  
T. Akasaka ◽  
K. Ishikawa ◽  
M. Matsuoka ◽  
E. Hirata ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Cell Proliferation ◽  
Body Fluid ◽  
Biomedical Applications ◽  
Cell Edge ◽  
The One ◽  
Single Walled Cnts ◽  
Cells Cultured ◽  
Walled Cnts ◽  
Multiwalled Cnts

Carbon nanotubes (CNT) and their derivatives with different structure and compositions have unique features. In the present study, cell proliferation was performed on various nanotubes such as single walled CNTs, multiwalled CNTs and imogolite which is nanotubes of aluminosilicate. SEM observation of the growth of osteoblast-like cells cultured on CNTs showed the morphology fully developed for the whole direction, which was different from that extended to the one direction on the usual scaffold. Numerous filopodia were grown from cell edge, extended far long and combined with CNT meshwork. Apatite precipitation in simulated body fluid, affinity for proteins and saccharides, and nanosize meshwork structure with large porosity would be the properties responsible for these cell adhesion and growth. Imogolite showed the similar properties to CNTs. Nanotubes could be the favorable materials for biomedical applications.

scholarly journals Dispersion of Carbon Nanotubes with “Green” Detergents

Molecules ◽  
2021 ◽  
Vol 26 (10) ◽  
pp. 2908
Author(s):  
Kazuo Umemura ◽  
Ryo Hamano ◽  
Hiroaki Komatsu ◽  
Takashi Ikuno ◽  
Eko Siswoyo
Keyword(s):  
Carbon Nanotubes ◽  
Sodium Dodecyl ◽  
Detergent Solution ◽  
Absorbance Spectroscopy ◽  
Fundamental Research ◽  
The Stability ◽  
Single Walled Cnts ◽  
Better Than ◽  
Walled Cnts ◽  
Cnt Suspensions

Solubilization of carbon nanotubes (CNTs) is a fundamental technique for the use of CNTs and their conjugates as nanodevices and nanobiodevices. In this work, we demonstrate the preparation of CNT suspensions with “green” detergents made from coconuts and bamboo as fundamental research in CNT nanotechnology. Single-walled CNTs (SWNTs) with a few carboxylic acid groups (3–5%) and pristine multi-walled CNTs (MWNTs) were mixed in each detergent solution and sonicated with a bath-type sonicator. The prepared suspensions were characterized using absorbance spectroscopy, scanning electron microscopy, and Raman spectroscopy. Among the eight combinations of CNTs and detergents (two types of CNTs and four detergents, including sodium dodecyl sulfate (SDS) as the standard), SWNTs/MWNTs were well dispersed in all combinations except the combination of the MWNTs and the bamboo detergent. The stability of the suspensions prepared with coconut detergents was better than that prepared with SDS. Because the efficiency of the bamboo detergents against the MWNTs differed significantly from that against the SWNTs, the natural detergent might be useful for separating CNTs. Our results revealed that the use of the “green” detergents had the advantage of dispersing CNTs as well as SDS.

In Situ Growth of Carbon Nanotubes in Hydroxyapatite Matrix by Chemical Vapor Deposition

2009 ◽  
Vol 79-82 ◽  
pp. 1671-1674 ◽  
Author(s):  
Xiao Ying Lu ◽  
Hao Wang ◽  
Sheng Yi Xia ◽  
Jian Xin Wang ◽  
Jie Weng
Keyword(s):  
Mechanical Properties ◽  
Carbon Nanotubes ◽  
Chemical Vapor Deposition ◽  
Vapor Deposition ◽  
Biomedical Applications ◽  
Chemical Vapor ◽  
Novel Method ◽  
Biomedical Fields ◽  
Walled Cnts

Carbon nanotubes (CNTs)/hydroxyapatite (HA) nanocomposites have been successfully fabricated by a novel method for the biomedical applications, which is in situ growing CNTs in HA matrix in a chemical vapor deposition (CVD) system. The results show that it is feasible to in situ grow CNTs in HA matrix by CVD for the fabrication of CNTs/HA nanocomposites. Multi-walled CNTs with 50-80 nm in diameter have been grown in situ from HA matrix with the pretreatment of sintering at 1473K in air. The nanocomposites are composed with carbon crystals in CNTs form, HA crystallites and calcium phosphate crystallites, one of most important CaP bioceramics. And the CNTs content is about 1% proportion by weight among the composites in our experiments, which can enhance the HA mechanical properties and the CNTs content does not affect the HA performances. These CNTs/HA nanocomposites have the potential application in the biomedical fields.

scholarly journals Measurement and study of thermophysical properties of nanofluids with carbon nanotubes

2021 ◽  
Vol 2119 (1) ◽  
pp. 012117
Author(s):  
V Ya Rudyak ◽  
G R Dashapilov ◽  
A A Shupik
Keyword(s):  
Carbon Nanotubes ◽  
Electrical Conductivity ◽  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Thermophysical Properties ◽  
Weight Concentration ◽  
Multi Walled Carbon Nanotubes ◽  
Walled Carbon Nanotubes ◽  
Single Walled Cnts ◽  
Walled Cnts

Abstract This article is devoted to the study of the thermophysical properties of nanofluids with single-walled and multi-walled carbon nanotubes (CNT). Their weight concentration varied from 0.05 to 0.2%. Nanofluids, based on ethylene glycol and water, were studied. Dispersants were also used. The diffusion of CNT had been systematically investigated by the method of dynamic light scattering and their effective hydrodynamic dimensions were determined. The rheology and viscosity of all nanofluids were studied. It is shown that nanofluids are either pseu-doplastic or viscoplastic. Their rheology changes with increasing CNT concentration and temperature. However, in all cases, the viscosity of nanofluids with single-walled CNTs is signifi-cantly higher than that of nanofluids with multi-walled CNTs. In the last part, the electrical conductivity of all these nanofluids and the dispersants effect on it are investigated.

Controlled Deposition and Applied Field Alignment of Single Walled Carbon Nanotubes for CNT Device Fabrication.

2002 ◽  
Vol 739 ◽  
Author(s):  
Jan Smits ◽  
Buzz Wincheski ◽  
JoAnne Ingram ◽  
Neal Watkins ◽  
Jeff Jordan
Keyword(s):  
Carbon Nanotubes ◽  
Electronic Transport ◽  
Device Fabrication ◽  
Self Assembled Monolayer ◽  
Si Substrates ◽  
Metallic Contacts ◽  
Controlled Deposition ◽  
Walled Carbon Nanotubes ◽  
Single Walled Cnts ◽  
Walled Cnts

ABSTRACTCarbon nanotubes (CNTs) offer great potential for advanced sensing devices due to their unique electronic transport properties. However, a significant obstacle to the realization of practical CNT devices is the formation of controlled, reliable and reproducible CNT to metallic contacts. In this work, a procedure for the deposition and alignment of CNTs onto metallic electrodes using chemically functionalized lithographic patterns is reported. This method uses photo and electron beam lithography to pattern simple Cr/Au thin film circuits on oxidized Si substrates. The circuits are then re-patterned with a self-assembled monolayer (SAM) of 3-aminopropyltriethoxysilane (APTES) to specify desired CNT locations between electrodes. The application of an electric field to the metallic contacts during the deposition of solution suspended single walled CNTs causes alignment of the CNTs in the field direction. This method consistently produces aligned CNTs in the defined locations.

scholarly journals Safe Administration of Carbon Nanotubes by Intravenous Pathway in BALB/c Mice

Nanomaterials ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 400 ◽  
Author(s):  
José Jesús Guzmán-Mendoza ◽  
Silvia Lorena Montes-Fonseca ◽  
Ernesto Ramos-Martínez ◽  
Carmen González-Horta ◽  
Pilar del Carmen Hernández-Rodríguez ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Toxic Effect ◽  
Biomedical Applications ◽  
Fluorescein Isothiocyanate ◽  
Drug Carriers ◽  
In Vivo Models ◽  
Post Exposure ◽  
Pristine Cnts ◽  
Walled Cnts

Carbon nanotubes (CNTs) are nanomaterials with multiple possible uses as drug carriers or in nanovaccine development. However, the toxicity of CNTs administered intravenously in in vivo models has not been fully described to date. This work aimed to evaluate the toxic effect of pristine multi-walled CNTs (UP-CNTs), purified (P-CNTs), or CNTs functionalized with fluorescein isothiocyanate (FITC-CNTs) administered by intravenous injection in BALB/c mice. Biochemical and histopathological parameters were analyzed at 1, 14, 29, and 60 days post-exposure. Pristine CNTs were the most toxic nanoparticles in comparison with P-CNTs or FITC-CNTs, increasing serum AST (≈ 180%), ALT (≈ 300%), and LDH (≈ 200%) levels at one day post-exposure. The urea/creatinine ratio suggested pre-renal injury at the 14th day accompanied of extensive lesions in kidneys, lungs, and liver. Biochemical and histological findings in mice exposed to P-CNTs had not significant differences compared to the controls. A lower toxic effect was detected in animals exposed to FITC-CNTs which was attributable to FITC toxicity. These results demonstrate that the purification process of CNTs reduces in vivo toxicity, and that toxicity in functionalized CNTs is dependent on the functionalized compound. Therefore, P-CNTs are postulated as potential candidates for safe biomedical applications using an intravenous pathway.

scholarly journals Antimicrobial Effect of Multilayered Carbon Nanotubes on Multi-Drug-Resistant Pseudomonas aeruginosa

2019 ◽  
Author(s):  
Hadis Mousavi ◽  
Hamideh Rouhani Nejad ◽  
Masoud Zandi ◽  
Amir Khodavirdi Pour
Keyword(s):  
Carbon Nanotubes ◽  
Pseudomonas Aeruginosa ◽  
Defense Mechanisms ◽  
Methicillin Resistance ◽  
Antimicrobial Effect ◽  
Inhibitory Effect ◽  
Drug Resistant ◽  
Minimal Inhibitory Concentrations ◽  
Single Walled Cnts ◽  
Walled Cnts

Background: Pseudomonas aeruginosa is the primary cause of infection with impaired defense mechanisms. P. aeruginosa commonly causes nosocomial infections and is the most common pathogen isolated from patients hospitalized for longer than 1 week. We examined the antimicrobial effect of multilayered carbon nanotubes on multi-drug-resistant. Materials and Methods: In this research, 20 clinical isolates collected at Motahari Hospital (Tehran, Iran) were compared with the standard (ATCC 27853) and identified as P. aeruginosa based on biochemical testing. Conventional disk diffusion assay demonstrated the methicillin resistance of the isolates. Minimal inhibitory concentrations for antibiotics and the multilayer CNTs were determined using the microdilution method. Single-walled CNTs were prepared and their efficacy and potential synergism with antibiotics was assessed. Results: Synergism against P. aeruginosa was evident for methicillin + single-walled CNTs. Conclusion: The inhibitory effect of single-walled CNTs and methicillin was synergistic against the growth of P. aeruginosa.

CMOS Compatible Growth of Carbon Nanotubes and Their Application in Field-Effect Transistors

2012 ◽  
Vol 1407 ◽  
Author(s):  
T. Uchino ◽  
G. N. Ayre ◽  
D. C. Smith ◽  
J. L. Hutchison ◽  
C. H. de Groot ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Field Effect ◽  
Defect Density ◽  
Field Effect Transistors ◽  
State Of The Art ◽  
Chemical Vapor ◽  
Radial Breathing Mode ◽  
Metal Catalyst ◽  
Single Walled Cnts ◽  
Walled Cnts

ABSTRACTThe metal-catalyst-free growth of carbon nanotubes (CNTs) using chemical vapor deposition and the application in field-effect transistors (FETs) is presented. The CNT growth process used a 3-nm-thick Ge layer on SiO2 that was subsequently annealed to produce Ge nanoparticles. Raman measurements show the presence of radial breathing mode (RBM) peaks and the absence of the disorder induced D-band, indicating single walled CNTs (SWNTs) with a low defect density. The synthesized CNTs are used to fabricate CNTFETs and the best device has a state-of-the-art on/off current ratio of 3×108 and a steep sub-threshold slope of 110 mV/decade.

scholarly journals Shielding effects in thin films of carbon nanotubes within microwave range

2016 ◽  
Vol 56 (2) ◽  
Author(s):  
Alesia Paddubskaya ◽  
Mikhail Shuba ◽  
Gintaras Valušis ◽  
Polina Kuzhir ◽  
Sergey Maksimenko ◽  
...  
Keyword(s):  
Thin Films ◽  
Carbon Nanotubes ◽  
Microwave Frequency ◽  
Microwave Range ◽  
Different Types ◽  
Em Field ◽  
Shielding Properties ◽  
Single Walled Cnts ◽  
Shielding Effects ◽  
Walled Cnts

The electromagnetic shielding properties of thin films comprising different types of carbon nanotubes (CNTs) were analysed in the microwave frequency range (26–36 GHz). A comparative analysis of the shielding properties was achieved for films based on long and short single-, double- and multi-walled CNTs. The experimental results proved that long-length single-walled CNTs demonstrate the highest interaction with the electromagnetic (EM) field, thereby providing the best shielding efficiency. At the same time, double-walled CNTs demonstrate a higher level of absorption ability (50%) along with the overall high EM shielding efficiency (88%), which makes them attractive for using in nanoelectronics screens as they produce the smallest secondary EM pollution.

FABRICATION OF CARBON NANOTUBE FIELD EFFECT TRANSISTORS WITH OCMC DISPERSED SINGLE-WALLED CARBON NANOTUBES

2010 ◽  
Vol 09 (04) ◽  
pp. 377-381
Author(s):  
KUMAR RAJ ◽  
QING ZHANG ◽  
LIANGYU YAN ◽  
MARY B. CHAN PARK
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Field Effect ◽  
Field Effect Transistors ◽  
Single Walled Carbon Nanotubes ◽  
Oxygen Adsorption ◽  
P Type ◽  
Walled Carbon Nanotubes ◽  
Single Walled Cnts ◽  
Walled Cnts

We report on the fabrication of carbon nanotube field effect transistors (CNTFETs) from dispersed single-walled CNTs using OCMC (O-Carboxymethylchitosan) as the surfactant. The as-prepared devices exhibit p-type as well as ambipolar characteristics due to oxygen adsorption at the metal/nanotube contacts. The Raman scattering from the SWCNTs shows that OCMC disperses CNTs efficiently. Rapid thermal annealing (RTA) at 400°C for 5 min is found to partially remove OCMC from the surface of SWCNTs.

scholarly journals In Vitro Cell Responses of MG-63 Osteoblast Cells on Bioactive Diopside and Wollastonite Nano-Bioceramics for Biomedical Applications

2020 ◽  
Author(s):  
Ruhollah Zamani Foroushani ◽  
Ebrahim Karamian ◽  
Mohammad Rafienia
Keyword(s):  
Cell Proliferation ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Biomedical Applications ◽  
Silicate Network ◽  
Osteoblast Cells ◽  
Alizarin Red ◽  
Cell Responses ◽  
The Stability

Abstract The present study aimed to synthesize and characterize diopside (CaMgSi2O6) and wollastonite (CaSiO3) nano-bioceramics via a combination of mechano-chemical and calcination processes. In vitro biomineralization and cell responses of wollastonite and diopside were performed on simulated body fluid (SBF) and MG-63 osteoblast cells. Results revealed proper tissue biomineralization of wollastonite and diopside through the generation of an apatite-like layer on the surface of nano-bioceramics. Cell responses of wollastonite and diopside eventuated non-cytotoxicity by MG-63 osteoblast cells, and their viability and cell proliferation were confirmed. Alizarin red staining of diopside and wollastonite evidenced great bioactivity and tissue biomineralization, and the ALP enzyme of diopside and wollastonite was enhanced in contact with the MG-63 osteoblast cells. Regarding the existence of Mg2+ in the calcium-silicate network and the stability network, diopside illustrated high biological and cell responses in comparison to wollastonite, and both of them were suggested as bioactive and biocompatible nano-bioceramics for biomedical applications.

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