Bioactive Gelatin-Siloxane Hybrids as Tissue Engineering Scaffold

2006 ◽  
Vol 111 ◽  
pp. 13-18 ◽  
Author(s):  
Lei Ren ◽  
Akiyoshi Osaka ◽  
B. Yu ◽  
Wei Shi ◽  
Dong Tao Ge ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Freeze Drying ◽  
Ph Value ◽  
Sol Gel ◽  
Freezing Temperature ◽  
Structure Change ◽  
Pore Characteristics ◽  
Biodegradable Scaffolds ◽  
Antibiotic Drug ◽  
Sol Gel Process

Ca2+-containing porous gelatin-siloxane hybrids were prepared using sol-gel process, post-gelation soaking, and freeze-drying. The porosity and pore size of the hybrids could be well controlled by the freezing temperature and the pH value of the soaking solution. The pore characteristics were related to the structure change during the soaking treatment. A bone-like apatite layer was able to form in the Ca2+-containing porous gelatin-siloxane hybrids upon soaking in a stimulated body fluid. The porous gelatin-siloxane hybrids could release gentamicin sulfate which is an antibiotic drug in bone chemotherapy. Thus, those hybrid materials are proposed to find application as novel bioactive and biodegradable scaffolds in bone tissue engineering.

In vitro Apatite Deposition and Biodegradation of Porous Gelatin-Silicate Hybrids Derived from Sol-Gel Process

2000 ◽  
Vol 628 ◽  
Author(s):  
Lei Ren ◽  
Kanji Tsuru ◽  
Satoshi Hayakawa ◽  
Akiyoshi Osaka
Keyword(s):  
Freeze Drying ◽  
Sol Gel ◽  
Freezing Temperature ◽  
Biodegradation Rate ◽  
Buffer Solution ◽  
Bioactive Scaffolds ◽  
Sol Gel Process ◽  
Gel Processing ◽  
Tris Buffer Solution

ABSTRACTCa (II) containing porous hybrids of gelatin and 3-(glycidoxypropyl) trimethoxysilane (GPSM) were prepared with sol-gel processing and freeze-drying techniques. The freezing temperature could control porosity and pore size of the hybrids. The biodegradation rate of the hybrids in a Tris buffer solution decreased with an increase in GPSM content. The bone-like apatite layer could form on the Ca (II) containing porous gelatin-silicate hybrids when they were soaked in a stimulated body fluid (SBF), hence they were applicable to be the bioactive scaffolds for bone tissue engineering.

scholarly journals Fabrication Of Carbon Aerogels From Coir For Oil Adsorption

2022 ◽  
Vol 964 (1) ◽  
pp. 012033
Author(s):  
Hieu M Nguyen ◽  
Khoi A Tran ◽  
Tram T N Nguyen ◽  
Nga N H Do ◽  
Kien A Le ◽  
...  
Keyword(s):  
Freeze Drying ◽  
Oil Spills ◽  
Sol Gel ◽  
Urea Solution ◽  
Carbon Aerogels ◽  
Low Density ◽  
High Porosity ◽  
Motor Oil ◽  
Sol Gel Process ◽  
Oil Adsorption

Abstract Coir, known as coconut fibers, are an abundant cellulosic source in Vietnam, which are mostly discarded when copra and coconut water are taken, causing environmental pollution and waste of potential biomass. In this research, carbon aerogels from chemically pretreated coir were successfully synthesized via simple sol-gel process with NaOH-urea solution, economical freeze-drying, and carbonization. The samples, including pretreated coir, coir aerogels, and carbon aerogels, are characterized using FTIR spectroscopy, SEM, XRD spectroscopy, and TGA. The carbon aerogels exhibit low density (0.034–0.047 g/cm3), high porosity (97.63–98.32 %), and comparable motor oil sorption capacity (22.71 g/g). The properties of carbon aerogels are compared with those of coir aerogels, indicating such better values than those of coir aerogels. Coir-derived carbon aerogels is a potential replacement for the hydrophobically-coated cellulose aerogels in term of treating oil spills.

Effect of pH Value on Preparation of La2CuO4 Microcrystallites Synthesized by Sol-Gel Process

2012 ◽  
Vol 512-515 ◽  
pp. 231-234 ◽  
Author(s):  
Yi Feng Li ◽  
Jian Feng Huang ◽  
Li Yun Cao ◽  
Jian Peng Wu
Keyword(s):  
Optical Band Gap ◽  
Ph Value ◽  
Raw Materials ◽  
Sol Gel ◽  
Complexing Agent ◽  
Solution Ph ◽  
Crystallization Property ◽  
Water As Solvent ◽  
Sol Gel Process ◽  
Single Sphere

La2CuO4 crystallites were prepared via a sol-gel process using lanthanum nitrate and cupric nitrate as raw materials, distilled water as solvent, citric acid as complexing agent and ammonia to control the pH value. The as-prepared La2CuO4 crystallites were characterized by XRD, FESEM, TEM and UV-Vis spectra. Results show that the crystallization property of La2CuO4 crystallites increases firstly and then decreases with increasing of the solution pH value from 1.0 to 2.5, but all of the samples exhibit single sphere-like morphology. It is found that when the solution pH value is controlled at 2.0, the grains display uniform distribution and the size ranges from 100nm to120nm after sintering at 600°C for 2 hours. The optical band gap of the as-prepared La2CuO4 crystallites is calculated to be 1.38eV.

Synthesis and Characterization of Li-Ti-O Nano-Composites and Their Doped BaTiO3 Based X7R-Type Ceramics

2010 ◽  
Vol 148-149 ◽  
pp. 1575-1579
Author(s):  
Qing Zhang ◽  
Rui Yuan Niu ◽  
Min Wang ◽  
Bin Cui ◽  
Zhu Guo Chang
Keyword(s):  
Particle Size ◽  
Dielectric Properties ◽  
Ph Value ◽  
Sol Gel ◽  
Nano Composites ◽  
X Ray Diffraction ◽  
Transmission Electron ◽  
Minimum Particle Size ◽  
Sol Gel Process

Li-Ti-O (abbreviated as LTO) nano-composites were synthesized via sol-gel process, and then doped BaTiO3 based X7R type ceramics. The LTO nano-composites and their ceramics were characterized by means of thermaogravimetric, Fourier-transform infrared, X-ray diffraction methods, transmission electron microscopy. We also characterized the dielectric properties of the LTO doped BaTiO3 based ceramics of X7R type. The results indicated that LTO nano-composites were nanometer scale powders. The pH value and calcining temperature had an influence on particle size of LTO sintering aids. At pH about 3 and with calcining at 600 °C, the nano-composites attained minimum particle size (about 10 nm). By adding 0.10 wt% of the LTO nano-composites, the temperature permittivity achieved about 4200 when sintered at 1240 °C for 4 h, and the dielectric properties met X7R standard.

Effect of TiO2 addition on the preparation of β-spodumene powders by sol-gel process

1999 ◽  
Vol 14 (1) ◽  
pp. 196-203 ◽  
Author(s):  
Moo-Chin Wang ◽  
Ming-Hong Lin ◽  
Hok-Shing Liu
Keyword(s):  
Electron Microscopy ◽  
Ph Value ◽  
Sol Gel ◽  
Gelation Time ◽  
Glass Ceramics ◽  
X Ray Diffraction ◽  
Transmission Electron ◽  
Sol Gel Process ◽  
Fine Glass ◽  
A Minor

This study has shown the possibility of achieving two primary considerations for the advanced fabrication of spodumene with a composition of Li2O · Al2O3 · 4SiO2 · nTiO2 (LAST) glass-ceramics by a sol-gel process, namely, an enormous reduction of sintering temperature from 1600 to 1200 °C together with the appearance of simple phases of β-spodumene/rutile as opposed to products via the conventional melting-crystallization process. Fine glass-ceramic powders with a composition of Li2O · Al2O3 · 4SiO2 (LAS) have been synthesized by the sol-gel process using Si(OC2H5)4, Al(OC2H5)3, LiOCH3, and Ti(OC2H5)4 as the starting materials. The process included well-controlled hydrolysis polycondensation of the raw alkoxides. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and electron diffraction (ED) analysis were utilized to study the effect of TiO2 addition on the preparation of β-spodumene powders by the sol-gel process. The gelation time of the LAST solution increases as the TiO2 content increases. For the low (<3) or high (>11) pH value, the gelation time was shortened. At pH = 5, regardless of the TiO2 content, the gel has the longest time of gelation. When the dried gels of the LAST system are heated from 800 to 1200 °C, the crystallized samples are composed of the major phase of β-spodumene and a minor phase of rutile (TiO2).

Preparation and Characterization of ZrO2 Coating by Sol-Gel on Mullite Short Fiber

2013 ◽  
Vol 591 ◽  
pp. 66-69
Author(s):  
Ying Na Zhao ◽  
Meng Zhang ◽  
Jiang Ren ◽  
Xiong Feng Zeng
Keyword(s):  
Heat Treatment ◽  
Ph Value ◽  
Sol Gel ◽  
Ceramic Materials ◽  
Short Fiber ◽  
Material Strength ◽  
Mullite Ceramic ◽  
Mullite Fiber ◽  
Sol Gel Process

The modified mullite fiber was used to toughen the mullite ceramic, which can effectively overcome the brittleness of ceramic materials and improve the material strength and toughness. Using 8ZrOCl2•H2O as precursor, anhydrous ethanol as solvent, H2O2 as hydrolysis promoter and NH3·H2O as precipitant, the stable and transparent zirconium sol could be obtained by sol-gel process, which coated mullite short fiber. The results showed that the stable and transparent ZrO2 sol was obtained when pH value was 3.8~4.8 and reaction temperature was at 25°C. XRD results indicated that monoclinic ZrO2 particles grew up and formed after heat-treatment at 700°C. The coating ZrO2 film combined with mullite fiber homogeneously and closely, and the film thickness was about 1 μm.

scholarly journals Self-Healing Coating on Aluminium Alloy (AA2014) using a Sol - Gel Process

2021 ◽  
Vol 9 (VI) ◽  
pp. 293-300
Author(s):  
Saurabh Kumar Jha
Keyword(s):  
Aluminium Alloy ◽  
Electrochemical Impedance ◽  
Ph Value ◽  
Sol Gel ◽  
Low Frequency ◽  
Barrier Properties ◽  
Immersion Test ◽  
Self Healing ◽  
High Impedance ◽  
Sol Gel Process

In this paper, a new doping concept has been improved which shows self-healing properties by sustained release of corrosion inhibitors in a carrier system. The anti-corrosive properties of (AA2014) aluminium alloy was tested by electrochemical impedance spectroscopy. The sol-gel coating doped with both inorganic and organic inhibitors gives a satisfying result. Releasing the event of inhibitor depends on the pH value of the corrosion environment. The barrier properties of the best coating divulge by high pore resistance with having high impedance value at low frequency. The immersion test confirmed that double doping concept is valuable also for long immersion test.

Study on the Photocatalytic Degration of Diesel Pollutants in Seawater by Li+-Doped Nano-TiO2

2013 ◽  
Vol 785-786 ◽  
pp. 459-462
Author(s):  
Ji Yao Guo ◽  
Xiao Cai Yu ◽  
Xiao Xv ◽  
Jin Fang Chen ◽  
Yun Qing Liu
Keyword(s):  
Crystal Structure ◽  
Reaction Time ◽  
Calcination Temperature ◽  
Ph Value ◽  
Removal Rate ◽  
Sol Gel ◽  
Initial Concentration ◽  
Sol Gel Process ◽  
Diesel Degradation

Li+-doped nanoTiO2particles with various amounts of dopant Li+irons have been synthesized by a sol-gel process. The products were characterized by XRD and SEM.Which revealed that the crystal structure of Li+-doped nanoTiO2is anatase, and the nanoparticles diameter was 42nm. Five factous, including dosage of Li+-doped nanoTiO2, initial concentration of diesel, pH value , photocatalytic degradetion reaction time and the presence of H2O2, are considered in the diesel degradation experiments. The results manifest that Li+-doped nanoTiO2can be used as photocatalyst to removal diesel pollutants in seawater effectively. When the ratio of Li+doped into TiO2is 1%wt, the calcination temperature of Li-doped nanoTiO2is 500°C, the dosage of the Li+-doped nanometer TiO2is 0.4g/L, the initial concentration of diesel is 0.2g/L, pH value is 7.0, the reaction time is 2.5h and the H2O2dosage is 0.2g/L, the removal rate of diesel pollutants is up to 88.10%.

scholarly journals Physicochemical Characterization and Drug Release Properties of Methyl-Substituted Silica Xerogels Made Using Sol–Gel Process

2021 ◽  
Vol 22 (17) ◽  
pp. 9197
Author(s):  
Adél Len ◽  
Giuseppe Paladini ◽  
Loránd Románszki ◽  
Ana-Maria Putz ◽  
László Almásy ◽  
...  
Keyword(s):  
High Performance ◽  
Ph Value ◽  
Sol Gel ◽  
Physicochemical Characterization ◽  
Silica Xerogels ◽  
Silica Network ◽  
Characterization Methods ◽  
X Ray ◽  
Starting Point ◽  
Sol Gel Process

In this work, a multi-analytical approach involving nitrogen porosimetry, small angle neutron and X-ray scattering, Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopies, X-ray diffraction, thermal analysis and electron microscopy was applied to organically modified silica-based xerogels obtained through the sol–gel process. Starting from a tetraethoxysilane (TEOS) precursor, methyltriethoxysilane (MTES) was added to the reaction mixture at two different pH values (2.0 and 4.5) producing hybrid xerogels with different TEOS/MTES molar ratios. Significant differences in the structure were revealed in terms of the chemical composition of the silica network, hydrophilic/hydrophobic profile, particle dimension, pore shape/size and surface characteristics. The combined use of structural characterization methods allowed us to reveal a relation between the cavity dimensions, the synthesis pH value and the grade of methyl substitution. The effect of the structural properties on the controlled Captopril release efficiency has also been tested. This knowledge facilitates tailoring the pore network for specific usage in biological/medical applications. Knowledge on structural aspects, as reported in this work, represents a key starting point for the production of high-performance silica-based hybrid materials showing enhanced efficacy compared to bare silica prepared using only TEOS.

Effect of Different Reaction Solvents on the Hydrophobic and Structural Properties of Silica Cryogels

2010 ◽  
Vol 663-665 ◽  
pp. 1238-1241
Author(s):  
Li Fen Su ◽  
Lei Miao ◽  
Sakae Tanemura ◽  
Gang Xu
Keyword(s):  
Specific Surface ◽  
Surface Area ◽  
Specific Surface Area ◽  
Freeze Drying ◽  
Sol Gel ◽  
Base Catalysis ◽  
Molar Ratio ◽  
Nitrogen Absorption ◽  
Acid Base ◽  
Sol Gel Process

The experimental results on the microstructural and physical properties of the TEOS-based silica cryogels have been reported. The cryogels were produced by two-step sol-gel process followed by vacuum freeze drying. The wet gels were synthesized via acid-base catalysis using tetraethoxysilane (TEOS) as a silica precursor, the different solvents containing ethanol (EtOH), methanol (MeOH) and tert-butanol (TBA), the molar ratio of TEOS / solvent were varied from 1:6 to 1:13. Further, the microstructure and specific surface area of the cryogels were analysed by Scanning Electron Microscopy (SEM) and nitrogen absorption/desorption isotherms. The hydrophobicity of the cryogels was studied by contact angle. It was found that the highest specific surface area (1040.17 m2 / g) was obtained with the solvent of MeOH. The lowest density (0.074 g/cm3) was acquired with the solvent of EtOH.

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