scholarly journals Association of ABO blood groups with dengue fever and its complications in a tertiary care hospital

2019 ◽  
Vol 11 (03) ◽  
pp. 265-269 ◽  
Author(s):  
Shivani Ravichandran ◽  
S. R. Ramya ◽  
Reba Kanungo
Keyword(s):  
Platelet Count ◽  
Dengue Fever ◽  
Blood Group ◽  
Clinical Laboratory ◽  
Tertiary Care ◽  
Blood Groups ◽  
Control Group ◽  
P Value ◽  
Care Hospital ◽  
Case Record

Abstract CONTEXT: Dengue fever (DF) has been steadily increasing in India with outbreaks in certain areas taking the proportion of epidemics. Along with secondary dengue, several risk factors predispose to dengue hemorrhagic fever and dengue shock syndrome. Very few studies associating the relationship between dengue and its severity with ABO blood group have been documented. AIMS: The aim of this study was to determine the association between distribution of ABO Rh blood groups and DF and DF with thrombocytopenia. SETTINGS AND DESIGN: This was a retrospective descriptive study conducted at the clinical laboratory of the department of microbiology. MATERIALS AND METHODS: Dengue patients whose case record contained information on blood group were screened for details of blood group and confirmed dengue diagnosis. Randomly 384 case records were selected. These were divided into two groups; Group 1 included DF cases (platelet count >20,000) and Group 2 included DF cases with thrombocytopenia (platelet count <20,000). Control group consisted of patients other than dengue, whose blood grouping had been done; randomly 390 were selected and analyzed. STATISTICAL ANALYSIS USED: P value was calculated using the Chi-square test. Odds ratio were calculated using the Fisher's exact test. RESULTS: DF was higher in 23% of individuals with AB blood group as compared to 8.5% of controls (P = 0.0004), whereas patients with blood group O were significantly less affected with DF (P = 0.0048). Disease severity was not associated with any of the blood groups. CONCLUSIONS: Individuals with AB blood group are more prone to DF, whereas individuals with blood group O are less prone.

scholarly journals CARICA PAPAYA LEAF EXTRACT FOR TREATING THROMBOCYTOPENIA IN DENGUE FEVER- AN EXPERIENCE FROM A TERTIARY CARE CENTRE IN EASTERN PART OF INDIA

2021 ◽  
pp. 38-41
Author(s):  
Satish Kr. Prasad ◽  
Sameer Kr. Mehta ◽  
Ankit Poddar
Keyword(s):  
Platelet Count ◽  
Dengue Fever ◽  
Leaf Extract ◽  
Carica Papaya ◽  
Tertiary Care ◽  
Control Group ◽  
P Value ◽  
Case Group ◽  
Study Group ◽  
And Control

Background: Dengue fever is the most common arboviral mosquito-borne tropical disease of humans caused by the dengue virus. The incidence has increased many fold in India due to unplanned urbanization and migration of population to urban areas. Aim -To study if Carica papaya leaf extract will significantly increase the platelet count in cases of thrombocytopenia associated with Dengue fever. Materials and Methods- The case control study was conducted in the Department of Medicine of Tata Main Hospital,Jamshedpur.All participants were randomised into two groups, study group (n=50) and control group (50); the study group was given papaya leaf extract capsule of 1100 mg thrice daily for five days but the control group did not receive it. The basic supportive treatment of dengue fever was provided to both the groups. Results- On the first day,platelet count of study group and control group was (63.68 ± 16.88, 3 and 57.07 ± 17.46×10 respectively, p value=0.0573). The mean platelet count on Day 2, Day 3, Day 4 of CPC 3 3 3 administration (mean± S.D) was 80.34 ± 18.54×10 ,104.14 ± 20.42×10 ,135.08 ± 19.91×10 in the case group and 64.48 ± 3 3 3 17.02×10 ,77.02 ± 16.88×10 ,100.70 ± 18.33×10 in the control group respectively.The mean duration of stay in the study group was 4.6± 0.67 days and 6.76±1.54 days in the control group (p<0.01). Conclusion- Carica papaya leaves extract capsules offer a cheap and possibly effective treatment for increasing the platelet count in dengue

scholarly journals Assessment of adverse drug reaction profile of the disease-modifying anti-rheumatic drugs at the department of orthopaedics in a tertiary care hospital, Silchar, Assam, India

2019 ◽  
Vol 8 (5) ◽  
pp. 1007
Author(s):  
Vijoy S. Kairi ◽  
Pinaki Chakravarty ◽  
Arun Kumar Sipani
Keyword(s):  
Prospective Observational Study ◽  
Tertiary Care Hospital ◽  
Early Recognition ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Case Record ◽  
Medical College ◽  
Disease Modifying ◽  
Reaction Profile

Background: The mainstay of treatment of Rheumatoid Arthritis (RA) is the use of the disease-modifying anti-rheumatic drugs (DMARDs). Methotrexate, sulfasalazine and hydroxychloroquine are some of the DMARDs which are used in combination for the treatment of RA. The current study was undertaken to assess the adverse drug reactions (ADRs) of DMARDs that are commonly encountered with the treatment of RA.Methods: The present study was designed as a prospective, observational study on newly diagnosed patients with RA. Patients diagnosed with RA above 18 years (excluding pregnant women) of either sex who were prescribed DMARDs in combination were included. ADRs reported spontaneously by the patients and also responses obtained in a questionnaire related to likely ADRs from the patients was recorded in the case record form. Statistical analysis was done using graph pad and p value <0.05 was considered to be statistically significant.Results: A total of 47 patients attending the Outpatient Department of Orthopaedics, Silchar Medical College and Hospital, Silchar, Assam, India were screened for the study. ADRs were monitored up to the last visit on 41 patients excluding the patients who were lost and who were not able to adhere to the treatment. A total of 27 ADRs were reported from 19 ADR forms. Gastrointestinal manifestations were the most common adverse effects of combination DMARDs seen in 10 patients (24.39%). Severity assessment done using modified Hartwig and Siegel scale that showed majority of the ADRs were mild (74.07%).Conclusions: Present study showed that DMARDs are well-tolerated and have an acceptable toxicity profile as majority of ADRs seen were mild. It was however difficult to prevent the occurrence of ADRs. Proper monitoring of therapy is needed for early recognition of ADRs.

scholarly journals Biochemical parameters (lactate dehydrogenase, serum albumin) as early predictor of severe dengue

2017 ◽  
Vol 4 (2) ◽  
pp. 464
Author(s):  
Poornima Shankar ◽  
Prarthana B.
Keyword(s):  
Lactate Dehydrogenase ◽  
Dengue Virus ◽  
Serum Albumin ◽  
Dengue Fever ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Severe Dengue ◽  
P Value ◽  
Care Hospital ◽  
Biochemical Tests

Background: Dengue fever (DF) is the arboviral infection with the largest incidence worldwide. Clinical expression of dengue virus infection varies from no symptoms to severe dengue with shock. It is the most rapidly spreading vector borne disease in the world. Nearly 100 million cases of Dengue fever and between 250,000 and 500,000 cases of severe dengue are annually reported to the WHO. The objective of this study was to study aims at determining the LDH and serum albumin levels as early parameter to predict the severity of Dengue illness.Methods: A observational clinical study conducted at K.I.M.S hospital, Bangalore, Karnataka, a tertiary care hospital. Children admitted in KIMS Hospital, Bangalore, Karnataka, a tertiary care hospital, Serum LDH and serum albumin levels are measured using the blood sample taken on the 3rd day of fever after confirmation of dengue fever (NS1 Ag- positive).Results: Study enrolled 150 patients with confirmed infection of Dengue virus who were admitted to paediatric unit between July 2014 and December 2016. Serum samples taken 72-96 hours within onset of fever were used for biochemical tests. Of 150 patients, 40 developed Severe Dengue (SD). Cases of SD had higher levels of lactate dehydrogenase (LDH) and low levels of serum albumin. Multivariate analysis showed that early alterations of LDH levels i.e.  Out of 40 patients who developed severe dengue, 37 patients i.e. 92.7% had raised levels of LDH with levels more than >600 IU and<3 levels of serum albumin 13 patients i.e 32.5% of severe dengue cases with P value of < 0.001, which showed significant association.Conclusions: Early alterations of biochemical parameter like LDH and serum albumin can predict Severe Dengue in patients with acute dengue illness.

scholarly journals ABO Blood Groups and the Risk of Venous Thromboembolism (VTE) Among Saudi Patients at a Tertiary Care Hospital in Riyadh

Blood ◽  
2019 ◽  
Vol 134 (Supplement_1) ◽  
pp. 4926-4926
Author(s):  
Ghaydaa Juma Kullab ◽  
Abdul Rehman Z. Zaidi ◽  
Sultan Albaqmi ◽  
Haya Alajlan ◽  
Mohammed Abdullah Alsheef
Keyword(s):  
Venous Thromboembolism ◽  
Blood Group ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Blood Groups ◽  
Blood Type ◽  
Care Hospital ◽  
Abo Blood Groups ◽  
Blood Types ◽  
Obesity Status

Background: ABO blood types are scientifically proved to be associated with the risk of venous thromboembolism (VTE), but data is lacking in the Saudi population. Aims: We aimed to investigate the association between ABO blood types and VTE, to explore potential interactions between ABO blood type with sex and obesity status. Methods: This was a retrospective study with a total of 998 patients, who were admitted with venous thromboembolism at our tertiary care hospital, between January 2010 and January 2018. Demographic and clinical data were collected. We used chi-square tests to assess the association between ABO blood group and the development of VTE. It was decided that the test will be considered significant if the p-value is <0.05. Results: Out of 998 VTE patients, 506 of patients were excluded, because their ABO blood group was not tested. Therefore, 492 patients were qualified as study subjects, of whom 66% of patients had DVT, 23% of patients had pulmonary embolism. Most of them had provoked VTE. Female patients constituted the majority of the study subjects (82.5%). Sample distribution appeared that O blood group was present in 34.1% of all VTE patients, while non-O-blood groups were present in 66% of them. Overall, there was a non-significant difference between VTE in patients with non-O blood type compared to O blood type (p=0.268). Conclusions: Non-O-blood groups (A, B, AB) are the most common blood types in Saudi patients with VTE. There is no statistically significant association between ABO blood groups, gender, and obesity status. Disclosures No relevant conflicts of interest to declare.

scholarly journals A Structured Maternity Case Record to Improve Quality of Documentation in a Tertiary Care Hospital, Delhi

2021 ◽  
Author(s):  
AG Radhika ◽  
Chetna Dengri ◽  
Abhishek Kumar ◽  
Shalini Singh
Keyword(s):  
Tertiary Care ◽  
Intervention Group ◽  
Control Group ◽  
Care Hospital ◽  
Case Record ◽  
Hospital Case ◽  
Sequence Of Events ◽  
Significant Difference ◽  
Time Of Admission

Introduction: India contributes to about 18% of global maternal deaths and 22.6% of still births. Efforts to improve the quality of care are challenged by the lack of reliable documentation of data. Hence, a concise, structured maternity case sheet (PrasavRecord) was designed with the aim to bring about an improvement in documentation of treatment and events related to woman in labour from the time of admission till her discharge from the hospital. Aim: To study the improvement in quality of documentation from the time of admission till discharge of a woman in labour with the help of structured format i.e., PrasavRecord. Materials and Methods: The study was conducted in February 2017. A quasi experimental study design was used, and the completeness of data recorded by the resident doctors in the existing hospital case sheet (control group) with those recorded in PrasavRecord (intervention group) were assessed in a total of 65 deliveries in each arm. Details of the patient from admission to the labour room followed by the entire sequence of events during labour as well as hospital stay in postpartum period were recorded over 130 parameters under different sections in PrasavRecord. Statistical analysis was done by using SPSS version 21.0. Results: Completeness of the documentation in terms of history, investigations and findings at examination including those at labour, nearly, 92% of the doctors rated PrasavRecord as “good and very good” for appearance, recommended its routine use, and 75% agreed that the format will be useful for conversion to electronic medical record. There was highly significant difference between the average percentage of completeness in PrasavRecord 75.8 {95% CI (74.2-77.4)} and hospital case sheets 42.2 {95% CI (40.9-43.6)} i.e., z=5.38 p-value <0.001. Conclusion: PrasavRecord is a simple, acceptable and user-friendly data entry format which improves the quality of documentation of the processes and practices during childbirth. Larger trials are required to finetune it to facilitate its widespread use thereby, ensuring a uniform documentation process of labour and postpartum.

scholarly journals A STUDY TO ASSESS THE CONTRAST SENSITIVITY OF THE HUMAN VISUAL SYSTEM IN PATIENTS WITH OR WITHOUT DIABETES IN A TERTIARY CARE HOSPITAL

2020 ◽  
pp. 24-26
Author(s):  
NIKITA RAJGADIA ◽  
BINDU BHASKARAN ◽  
N. DIVYA ◽  
V. PANIMALAR A. VEERAMANI ◽  
SYEDA SADIYA IKRAM
Keyword(s):  
Visual Acuity ◽  
Visual Impairment ◽  
Contrast Sensitivity ◽  
Tertiary Care ◽  
Dependent Diabetes Mellitus ◽  
Control Group ◽  
P Value ◽  
Care Hospital ◽  
Type Ii ◽  
Department Of Ophthalmology

Objective: The objective of our study was to assess the variations in contrast sensitivity values of normoglycemic subjects and that of type II diabetic subjects of the same age group. It was also aimed at finding the visual acuities and study the associations of it with contrast sensitivity if any. Methods: It was a hospital-based comparative cross-sectional descriptive study conducted in the out-patient department of the Department of Ophthalmology, Saveetha Medical College, Hospital, Chennai. Visual Acuity and Contrast Sensitivity of 50 Type II Diabetic individuals and 50 age-equivalent control group subjects were measured using the Snellen’s chart and Pelli-Robson chart, respectively, during the months of January to March 2020. Results: Contrast Sensitivity measurements from 50 subjects with Non-Insulin dependent Diabetes Mellitus (NIDDM) were obtained. The subjects were the ones who had minimal or no diabetic retinopathy. It was observed that there is a significant association between reduced contrast sensitivity and Diabetes (P value<.00008). We also noted that CS may be reduced without corresponding loss of Visual Acuity. Hence, both visual acuity and contrast sensitivity measurements are helpful in the assessment of visual impairment due to diabetic eye disease. Conclusion: The contrast sensitivity can be seen as an early marker for visual impairment in diabetic eye care.

scholarly journals Effect of Taping of Thoracic and Abdominal Muscles on Pelvic Alignment and Forward Reach Distance Among Stroke Subjects: A Randomized Controlled Trial

2019 ◽  
Vol 26 (3-4) ◽  
pp. 10-16
Author(s):  
Megha Mehta ◽  
Abraham M. Joshua ◽  
Suruliraj Karthikbabu ◽  
Zulkifli Misri ◽  
Bhaskaran Unnikrishnan ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Control Group ◽  
P Value ◽  
Abdominal Muscles ◽  
Care Hospital ◽  
Physiotherapy Treatment ◽  
Short Term ◽  
Randomized Controlled ◽  
Conventional Physiotherapy ◽  
Experimental Group

Introduction: The objective of this study was to find the immediate as well as short-term effect on pelvic alignment and forward arm reach distance in sitting among stroke patients following thoracic spine and abdominal muscles taping along with conventional therapy. Methods: Thirty subjects with stroke attending the physiotherapy programme at Department of Physiotherapy at a tertiary care hospital underwent this randomized controlled experimental study. Subjects in the experimental group received taping, along with conventional physiotherapy treatment, for restricting thoracic kyphosis and facilitating abdominal muscles. Subjects in the control group received only conventional physiotherapy treatment. To assess the change in pelvic alignment and forward arm reach distance while sitting, Palpation MeterTM (PALMTM) and sit and reach test were used, respectively. Results: In the experimental group, pelvic obliquity was corrected (4.1 ± 0.94) and anterior pelvic tilt revealed improvement (4.9 ± 2.1, p value < 0.001). In the control group, no improvement in pelvic alignment was recorded. Improvement in forward arm reach distance was similar in both groups ( p value = 0.804). Conclusion: Taping as an adjunctive treatment method to physiotherapy can cause immediate as well as short-term improvement of pelvic alignment in sitting, following stroke. It also, immediately improves the sit and reach distance in the same population.

“ASSOCIATION OF ABO & RH BLOOD GROUPS WITH HEPATITIS, HIV AND SYPHILIS INFECTIONS IN HEALTHY BLOOD DONORS AT TERTIARY CARE CENTRE”.

2021 ◽  
pp. 68-70
Author(s):  
Sonal Chitroda ◽  
Neha Patel ◽  
Pinal Solanki
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Tertiary Care ◽  
Blood Groups ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Group Type ◽  
Increased Risk ◽  
High Prevalence ◽  
Blood Group Type

Background: People from certain blood groups are more prone to develop infections transmitted by blood transfusion. In order to improve the management of such infections some hypothesis suggests that genetic predispositions like ABO and Rh blood groups would inuence the occurrence of such infections. Hence the present study aims to assess any possible associations of ABO & Rh blood groups with Hepatitis, HIV & syphilis infections in healthy blood donors. This was a retrospective study in heal Methods: thy blood donors of tertiary care hospital enrolled during years 2016 to 2020. Blood samples from total 34015 donors were screened for blood grouping & serology of HIV, Hepatitis & Syphilis. Result: Out of total donors only 171 donors were found positive for transfusion transmitted infections. Hepatitis B virus was found more prevalent compared to other infections. In ABO blood group type “B” and in Rh blood group type “Positive” was found more prevalent in donors. But it did not show any signicant association with transfusion transmitted infections. Conclusion: High prevalence of HBV infections in blood donors in present study point towards need of public health measures in general population. Undertaking further research to determine the special blood groups as increased risk for categorized donors is recommended.

scholarly journals FREQUENCY OF ABO AND RHESUS (D) BLOOD GROUPS IN DAKSHINA KANNADA DISTRICT OF KARNATAKA - A STUDY FROM RURAL TERTIARY CARE TEACHING HOSPITAL IN SOUTH INDIA

2014 ◽  
Vol 04 (03) ◽  
pp. 057-060
Author(s):  
Chandrika Rao ◽  
Jayaprakash Shetty
Keyword(s):  
Blood Group ◽  
Inventory Management ◽  
Tertiary Care ◽  
Blood Groups ◽  
Geographical Information ◽  
Blood Group System ◽  
Care Hospital ◽  
Human Beings ◽  
Group System ◽  
Group B

Abstract Background: ABO and Rh blood groups are most important blood groups in human beings. The frequency of four main blood group systems varies in population throughout the world and even in different parts of country. Objective if this study was to identify distribution of ABO and Rh blood group system. Materials and methods: The study was conducted in rural tertiary care hospital from January 2008 to December 2012. Data were collected from Blood Bank grouping records. All blood samples processed during period of observation were included in study. Results: During the period of observation total 43,103 numbers of blood groups were performed. Patient's samples were 28,305 and donor's samples were 14,798. The frequency of blood group O in our population was 42.0% (40.1% O Rh positive and 1.8% O Rh negative). The frequency of blood group B in our population was 27.3% (25.6% B Rh positive and 1.62% B Rh negative) followed by blood group A was 25.8% (24.3% A Rh positive and 1.4% A Rh negative) and blood group AB was 4.8% (4.4% AB Rh positive and 1.4% AB Rh negative) and a two Bombay blood group donors (0.0046%). Rh positive were 94.64% and Rh negative were 5.35%. Discussion: O positive blood group is significantly high in our population. Every transfusion centre should have a record of frequency of blood group system in their population. It helps in inventory management. Knowledge of blood group distribution is important for clinical studies, for reliable geographical information and for forensic studies in the population.

scholarly journals Association of microvascular complications of type 2 diabetes mellitus with ABO blood group

2019 ◽  
Vol 6 (3) ◽  
pp. 738
Author(s):  
Geetika Gupta ◽  
Bhavna Langer ◽  
Tabinda Shah ◽  
Anil K. Gupta ◽  
Mumtaz Goni
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Group ◽  
Tertiary Care ◽  
Blood Groups ◽  
Vascular Complication ◽  
Abo Blood Group ◽  
Care Hospital

Background: Micro vascular complications are the major outcome of Type 2 Diabetes Mellitus progression, which reduces the quality of life and increases diabetic morbidity & mortality. As the incidence of type 2 diabetes is growing day by day; our search for its aetiology and pathogenesis is also ever growing to predict its risk factors and early screening for better care and prevention of its complications. Many studies have tried to link susceptibility of type 2 diabetes with ABO blood group though results have been inconsistent. The present study aims to analyse association of micro vascular complication with different blood groups if any.Methods: A cross sectional study was conducted among patients of type 2 diabetes Mellitus in a tertiary care hospital. Determination of ABO and Rh status was done by standard slide method of agglutination. Detailed information about age, gender, BMI, duration of diabetes, age of onset of diabetes was noted with the help of a proforma. The records (clinical examination and investigations done by physician) were screened for type of micro vascular complications.Results: Out of a total of 319 patients suffering from type 2 diabetes, 209 subjects (65.15%) had one or the other complications. A statistically significant (p=0.00) difference was observed between the presence or absence of complications in different blood groups. In patients with Blood group B, 76.14% presented with complications. Though Nephropathy was the most common complication observed among different blood groups, none of the type of micro vascular complication was found to be significantly associated with different blood groups.Conclusions: The findings in our study suggest that although there was a significant association between presence or absence of complications and different blood groups, but this association was not significant for different types of complications.

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