Study of Phenolic Composition and Biological Activities Assessment of Olive Leaves from different Varieties Grown in Tunisia

Aim: This study was designed to investigate the phytochemical profile and the cytotoxic activities of the eco-friendly extracts of olive leaves from Chemlali cultivar. Materials and Methods: The Phenolic composition of olive leaves extracts, the antioxidant activity and the cytotoxic effects against MCF-7 and HepG2 cells were determined. Results: Olive leaves extracts showed relevant total polyphenols contents. Oleuropein was the major detected phenolic compound reaching a concentration of 16.9 mg/ml. The antioxidant potential of the studied extracts varied from 23.7 to 46.5mM Trolox equivalents as revealed by DPPH and ABTS assays. Cytotoxicity experiments showed similar trends for both HepG2 and MCF-7 cells with the infusion extract being the most active. Conclusion: This study denotes that olive leaves may have great potential as endless bioresource of valuable bioactive compounds which may have a wide application.

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Phenolic Composition and Antioxidant Activity of Plants Belonging to the Cephalaria (Caprifoliaceae) Genus

Plants ◽

10.3390/plants10050952 ◽

2021 ◽

Vol 10 (5) ◽

pp. 952

Author(s):

Małgorzata Chrząszcz ◽

Barbara Krzemińska ◽

Rafał Celiński ◽

Katarzyna Szewczyk

Keyword(s):

Antioxidant Activity ◽

Lung Diseases ◽

Antioxidative Activity ◽

Biological Activities ◽

Natural Antioxidants ◽

Antioxidant Effect ◽

In Vivo Studies ◽

Phenolic Composition

The genus Cephalaria, belonging to the Caprifoliaceae family, is a rich source of interesting secondary metabolites, including mainly saponins which display a variety of biological activities, such as immunomodulatory, antimicrobial and hemolytic effects. Besides these compounds, flavonoids and phenolic acids were identified in Cephalaria species. Cephalaria is employed in traditional medicine e.g., to cure cardiac and lung diseases, rheumatism, and regulate menstruation. In this review we focus on the phenolic compound composition and antioxidative activity of Cephalaria species. The antioxidant effect can be explained by flavonoids present in all parts of these plants. However, future efforts should concentrate more on in vitro and in vivo studies and also on clinical trials in order to confirm the possibility of using these plants as natural antioxidants for the pharmacology, food or cosmetic industries.

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Study the Effects of Olive Leaves Extracts in the activity of the enzyme GOT and their Biological Activities

Baghdad Science Journal ◽

10.21123/bsj.14.1.48-59 ◽

2017 ◽

Vol 14 (1) ◽

pp. 48-59

Author(s):

Baghdad Science Journal

Keyword(s):

Aqueous Extract ◽

Large Scale ◽

Chemical Elements ◽

Biological Activities ◽

Olive Tree ◽

Food Preservation ◽

The Body ◽

Aqueous Extracts ◽

Olive Leaf ◽

Olive Leaves

The olive tree, has been used it is important plant for the time being some of their parts on a large scale in the treatment of gastrointestinal disorders and stimulate circulation . Moreover, it is used as antibacterial material and also to address some of the respiratory system, diabetes, food preservation osteoporosis. This study involved the collection of olive leaves from different areas in Baghdad / Iraq. These leaves have been harvested, wash it, then dried and crushed, where the study aimed to identify the active ingredients and chemical elements in the olive leaf as well as its effect on the action of GOT enzyme .The study showed that the aqueous extracts (cold and hot) of the olive leaves powder are acidic in nature pH values are of (5.74 and 5.40) for the aqueous extracts hot and cold respectively. Study revealed the extract contain the a collection of Glycosides, tannins, phenolic compounds, resins, flavonoids, alkaloids, terpenes and compound Alaolurobin. The study also showed ability to activate the enzyme GOT in cold aqueous extract (8.36%). and the percentage (27.35%) of hot aqueous extract. That can be analyzed to the presence of higher concentrations of the active compounds in hot aqueous extract compared with cold aqueous extract especially tannins working to activate enzymes carrier in the cell membrane in the body. The study showed that the analysis of thin layer chromatography, liquid high-performance, ( TLC, HPLC) in extract compounds of phenols olive leaf using a mixture (chloroform, acetic acid) and a 2:5 was more impact in the Gram-positive Staphylococcus aureus, while less impact in a negative Gram Salmonella typhimurium. As proved accurate analysis of the chemical elements in powder of plant leaf olive tree and at different concentrations contain of chemical elements Major estimated by (g /kg) and trace estimated by (mg/kg). Since the existence of these elements led to increasing of enzymatic effectiveness through an increase process of activity the enzyme (GOT), which plays role of important in our bodies being gives indication of the nature of the work and effectiveness of the activity of some members of the body (liver, kidney, pancreas, etc.).

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Isolation of hydroxytyrosol from olive leaves extract, radioiodination and investigation of bioaffinity using in vivo/in vitro methods

Radiochimica Acta ◽

10.1524/ract.2013.2068 ◽

2013 ◽

Vol 101 (9) ◽

pp. 585-593 ◽

Cited By ~ 1

Author(s):

M. Ozkan ◽

F. Z. Biber Muftuler ◽

A. Yurt Kilcar ◽

E. I. Medine ◽

P. Unak

Keyword(s):

Small Intestine ◽

Phenolic Compounds ◽

Biological Activities ◽

In Vivo Studies ◽

Flavonoid Content ◽

Olive Leaves ◽

In Vitro Methods ◽

Extraction And Purification

Summary It is known that medicinal plants like olive have biological activities due to their flavonoid content such as olueropein, tyrosol, hydroxytyrosol etc. In current study, hydroxytrosol (HT) which is one of the major phenolic compounds in olive, olive leaves and olive oil, was isolated after methanol extraction and purification of olive leaves which are grown in the northern Anatolia region of Turkey. The isolated HT was radiolabeled with 131I (131I-HT) and the bioaffinity of this radiolabeled component of olive leaves extract was investigated by using in vivo/in vitro methods. It was found that HT could be radiolabeled with 131I in yields of 95.6±4.4% (n = 8), and in vivo studies showed that 131I-HT is taken up by urinary bladder, stomach, small intestine, large intestine, breast and prostate. Significant incorporation of activity was observed in cell lines via in vitro studies.

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A First Approach to the Chemical Composition and Antioxidant Potential of Guinea-Bissau Propolis

Natural Product Communications ◽

10.1177/1934578x19844138 ◽

2019 ◽

Vol 14 (5) ◽

pp. 1934578X1984413 ◽

Cited By ~ 1

Author(s):

Soraia I. Falcão ◽

Mélissa Lopes ◽

Miguel Vilas-Boas

Keyword(s):

Antioxidant Activity ◽

Chemical Composition ◽

Physicochemical Properties ◽

Natural Product ◽

Broad Spectrum ◽

Biological Activities ◽

Chemical Diversity ◽

Antioxidant Potential ◽

Phenolic Composition ◽

First Time

Propolis is a natural product derived from plant resins collected by honeybees and used in the beehive as a construction and defensive material. The broad spectrum of biological activities is dependent on the chemical diversity of its composition which is determined by the floral sources at the site of collection. For the first time, the chemical composition of Guinean propolis as well as its physicochemical properties, phenolic composition, and antioxidant activity was assessed. Eight compounds were identified through LC/DAD/ESI-MS n , mostly isoflavonoids, resembling Nigerian and Brazilian red propolis from the genus Dalbergia.

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Microbiological and Antioxidant Activity of Phenolic Compounds in Olive Leaf Extract

Molecules ◽

10.3390/molecules25245946 ◽

2020 ◽

Vol 25 (24) ◽

pp. 5946

Author(s):

Dragana Borjan ◽

Maja Leitgeb ◽

Željko Knez ◽

Maša Knez Hrnčič

Keyword(s):

Phenolic Compounds ◽

Leaf Extract ◽

Biological Activities ◽

Olive Leaf ◽

Olive Leaves ◽

Olive Leaf Extract ◽

Antimicrobial Potential ◽

Isolation And Characterization ◽

Wide Range

According to many reports, phenolic compounds isolated from olive leaves have very good biological activities, especially antimicrobial. Presently, the resistance of microorganisms to antibiotics is greater than ever. Therefore, there are numerous recent papers about alternative solutions for inhibiting their influence on human health. Olive leaf is studied as an important source of antimicrobials with low cost and used in medicine. Numerous publications on involving green technologies for isolation of active compounds from olive leaves have appeared over the past few decades. The present review reports on current knowledge of the most isolated phenolic compounds from olive leaf extract as well as methods for their isolation and characterization. This paper uses recent research findings with a wide range of study models to describe the antimicrobial potential of phenolic compounds. It also describes the vast range of information about methods for determination of antimicrobial potential focusing on effects on different microbes. Additionally, it serves to highlight the role of olive leaf extract as an antioxidants and presents methods for determination of antioxidant potential. Furthermore, it provides an overview of presence of enzymes. The significance of olive leaves as industrial and agricultural waste is emphasized by means of explaining their availability, therapeutic and nutritional effects, and research conducted on this field.

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Contribution of the phenolic composition to the antioxidant, anti-inflammatory and antitumor potential of Equisetum giganteum L. and Tilia platyphyllos Scop.

Food & Function ◽

10.1039/c6fo01778a ◽

2017 ◽

Vol 8 (3) ◽

pp. 975-984 ◽

Cited By ~ 16

Author(s):

Inés Jabeur ◽

Natália Martins ◽

Lillian Barros ◽

Ricardo C. Calhelha ◽

Josiana Vaz ◽

...

Keyword(s):

Biological Activities ◽

Phenolic Composition ◽

Naturally Occurring ◽

Antitumor Potential ◽

Tilia Platyphyllos ◽

Anti Inflammatory

Naturally-occurring phytochemicals have received pivotal attention in the last few years, due to the increasing evidence of biological activities.

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Study the Effects of Olive Leaves Extracts in the activity of the enzyme GOT and their Biological Activities

Baghdad Science Journal ◽

10.21123/bsj.2017.14.1.0048 ◽

2017 ◽

Vol 14 (1) ◽

Keyword(s):

Biological Activities ◽

Olive Leaves

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Nutritional Content and Antioxidant Capacity of the Seed and the Epicarp in Different Ecotypes of Pistacia atlantica Desf. Subsp. atlantica

Plants ◽

10.3390/plants9091065 ◽

2020 ◽

Vol 9 (9) ◽

pp. 1065 ◽

Cited By ~ 2

Author(s):

Amina Labdelli ◽

Abdelkrim Rebiai ◽

Mohammed Tahirine ◽

Ahmed Adda ◽

Othmane Merah

Keyword(s):

Human Health ◽

High Performance ◽

Biological Activities ◽

Reversed Phase ◽

Essential Elements ◽

Phenolic Composition ◽

Nutritional Values ◽

Pistacia Atlantica ◽

Phenolic Contents ◽

Calcium Phosphorus

Phenolic compounds are secondary metabolites that occur naturally in all plants. Seeds are among the richest organs of plants in phytochemicals, vitamins and minerals. These compounds and their biological activities are of great importance for human health. This study aimed to analyze the phenolic composition and their antioxidant activity in the seeds and epicarps of six Algerian populations of Pistacia atlantica Desf. subsp. atlantica growing along an aridity gradient from semi-arid to Saharan environmental conditions. Higher phenolic contents were observed in epicarp compared to seeds whatever the ecotype. The highest phenolic content of seeds and epicarps was observed in ecotype of Djelfa and the lowest values in Tiaret (T-Z). Phenolic composition, measured by reversed-phase high-performance liquid chromatography (HPLC), showed that quercetin in epicarp, gallic and chlorogenic acids in seeds were the most present in all ecotypes. Large differences were observed between ecotypes for nutritional values. Seeds were rich in flavonoids, proteins, carbohydrates and essential elements such as potassium, calcium, phosphorus and iron. These results highlighted the potential importance of Atlas pistachio fruits as a source of essential compounds that contribute to human health. Moreover, this underused species may serve a potential source for antioxidant components for alimentation and cosmetics purposes.

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